AU2015320230B2 - Uses of neuregulin in preventing, treating or delaying ventricular arrhythmia, and composition thereof - Google Patents

Uses of neuregulin in preventing, treating or delaying ventricular arrhythmia, and composition thereof Download PDF

Info

Publication number
AU2015320230B2
AU2015320230B2 AU2015320230A AU2015320230A AU2015320230B2 AU 2015320230 B2 AU2015320230 B2 AU 2015320230B2 AU 2015320230 A AU2015320230 A AU 2015320230A AU 2015320230 A AU2015320230 A AU 2015320230A AU 2015320230 B2 AU2015320230 B2 AU 2015320230B2
Authority
AU
Australia
Prior art keywords
ventricular
nrg
treating
pharmaceutical preparation
preventing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2015320230A
Other languages
English (en)
Other versions
AU2015320230A1 (en
Inventor
Mingdong Zhou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zensun Shanghai Science and Technology Ltd
Original Assignee
Zensun Shanghai Science and Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55580273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2015320230(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zensun Shanghai Science and Technology Ltd filed Critical Zensun Shanghai Science and Technology Ltd
Publication of AU2015320230A1 publication Critical patent/AU2015320230A1/en
Assigned to ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY CO., LTD. reassignment ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY CO., LTD. Alteration of Name(s) of Applicant(s) under S113 Assignors: ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY LIMITED
Application granted granted Critical
Publication of AU2015320230B2 publication Critical patent/AU2015320230B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AU2015320230A 2014-09-24 2015-09-06 Uses of neuregulin in preventing, treating or delaying ventricular arrhythmia, and composition thereof Active AU2015320230B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410529437.4 2014-09-24
CN201410529437.4A CN105497876B (zh) 2014-09-24 2014-09-24 神经调节蛋白用于预防、治疗或延迟心脏室性心律失常的方法和组合物
PCT/CN2015/088972 WO2016045493A1 (zh) 2014-09-24 2015-09-06 神经调节蛋白预防、治疗或延迟室性心律失常的用途及其组合物

Publications (2)

Publication Number Publication Date
AU2015320230A1 AU2015320230A1 (en) 2017-03-30
AU2015320230B2 true AU2015320230B2 (en) 2021-06-24

Family

ID=55580273

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015320230A Active AU2015320230B2 (en) 2014-09-24 2015-09-06 Uses of neuregulin in preventing, treating or delaying ventricular arrhythmia, and composition thereof

Country Status (9)

Country Link
US (1) US10441633B2 (enExample)
EP (1) EP3199174B1 (enExample)
JP (1) JP2017530127A (enExample)
KR (1) KR20170055492A (enExample)
CN (2) CN105497876B (enExample)
AU (1) AU2015320230B2 (enExample)
CA (1) CA2961813A1 (enExample)
RU (1) RU2017113775A (enExample)
WO (1) WO2016045493A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2822705C1 (ru) * 2023-11-03 2024-07-11 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ лечения некоронарогенной желудочковой парасистолии, регистрирующейся в покое

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0620819A2 (pt) 2005-12-30 2011-11-22 Zensun Shangai Science & Technology Ltd uso de uma neuregulina (nrg) de liberação prolongada, nrg em uma liberação prolongada de uma dosagem baixa constante, e, composição de liberação prolongada para prevenir, tratar ou retardar uma doença ou distúrbio em um mamìfero
JP6096262B2 (ja) 2009-08-25 2017-03-15 ゼンサン (シャンハイ) サイエンス アンド テクノロジー,シーオー.,エルティーディー. ニューレグリンに基づく心不全の治療方法
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun (Shanghai)Science & Technology Limited Compositions and methods for treating heart failure
JP6475623B2 (ja) 2012-10-08 2019-02-27 ゼンスン(シャンハイ)サイエンス アンド テクノロジー カンパニー リミテッド 糖尿病患者における心不全の治療用組成物
CA2911848A1 (en) 2013-05-22 2014-11-27 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for treating heart failure
CN110946993A (zh) 2014-01-03 2020-04-03 上海泽生科技开发股份有限公司 纽兰格林制剂的配方
CN105561298A (zh) 2014-10-17 2016-05-11 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
WO2020037076A1 (en) * 2018-08-14 2020-02-20 Emory University Inducing proliferation of cardiomyocytes and therapeutic uses related thereto
AR121035A1 (es) 2019-04-01 2022-04-13 Lilly Co Eli Compuestos de neuregulina-4 y métodos de uso
JP2022547335A (ja) * 2019-09-16 2022-11-11 ゼンサン (シャンハイ) サイエンス アンド テクノロジー,シーオー.,エルティーディー. 組換えヒトニューレグリン誘導体及びその使用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130196911A1 (en) * 2010-03-24 2013-08-01 Massachusetts Institute Of Technology Methods and compositions for cardioprotection and cardioregeneration

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7115554B1 (en) 1993-05-06 2006-10-03 Acorda Therapeutics, Inc. Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5834229A (en) 1991-05-24 1998-11-10 Genentech, Inc. Nucleic acids vectors and host cells encoding and expressing heregulin 2-α
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
CA2306228A1 (en) 1997-10-14 1999-04-22 Cambridge Neuroscience, Inc. Therapeutic methods comprising use of a neuregulin
AUPP785098A0 (en) 1998-12-21 1999-01-21 Victor Chang Cardiac Research Institute, The Treatment of heart disease
US6635249B1 (en) 1999-04-23 2003-10-21 Cenes Pharmaceuticals, Inc. Methods for treating congestive heart failure
CN1138785C (zh) 1999-06-04 2004-02-18 周明东 生长因子神经调节蛋白及其类似物的新应用
AUPQ105799A0 (en) 1999-06-18 1999-07-08 Victor Chang Cardiac Research Institute, The Cell growth inhibition
WO2003099320A1 (en) 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
CN1498656A (zh) * 2002-11-08 2004-05-26 上海泽生科技开发有限公司 神经调节蛋白用于心肌梗死治疗的方法和组合物
AU2006206778A1 (en) 2005-01-20 2006-07-27 Schuchean Chien Methods for QT interval control
US20070213264A1 (en) 2005-12-02 2007-09-13 Mingdong Zhou Neuregulin variants and methods of screening and using thereof
BRPI0620819A2 (pt) 2005-12-30 2011-11-22 Zensun Shangai Science & Technology Ltd uso de uma neuregulina (nrg) de liberação prolongada, nrg em uma liberação prolongada de uma dosagem baixa constante, e, composição de liberação prolongada para prevenir, tratar ou retardar uma doença ou distúrbio em um mamìfero
US9580515B2 (en) 2006-08-21 2017-02-28 Zensun (Shanghai) Science & Technology, Co., Ltd. Neukinase, a downstream protein of neuregulin
CN101310766B (zh) * 2007-05-25 2014-04-16 上海泽生科技开发有限公司 神经调节蛋白的新用途
US20090156488A1 (en) 2007-09-12 2009-06-18 Zensun (Shanghai) Science & Technology Limited Use of neuregulin for organ preservation
US8603817B2 (en) * 2008-11-03 2013-12-10 University Of Washington Induction of human embryonic stem cell derived cardiac pacemaker or chamber-type cardiomyocytes by manipulation of neuregulin signaling
EP2808339B1 (en) 2008-11-28 2017-02-15 Zensun (Shanghai) Science & Technology, Co., Ltd. Neuregulin peptides and their use
WO2010060266A1 (en) 2008-11-28 2010-06-03 Zensun (Shanghai) Science & Technology Limited Neuregulin and cardiac stem cells
CN102470161A (zh) 2009-06-09 2012-05-23 上海泽生科技开发有限公司 神经调节蛋白用于治疗心力衰竭的有效剂量
WO2010142141A1 (en) 2009-06-09 2010-12-16 Zensun (Shanghai) Science & Technology Limited Neuregulin based methods for treating heart failure
CN102139095A (zh) 2010-01-29 2011-08-03 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物
US20120028992A1 (en) * 2010-08-02 2012-02-02 Brown Arthur M Pharmaceutical compositions for terminating acute episodes of cardiac arrhythmia, restoring sinus rhythm, preventing recurrence of cardiac arrhythmia and/or maintaining normal sinus rhythm in mammals
WO2012054718A2 (en) 2010-10-22 2012-04-26 The General Hospital Corporation Treating long qt syndrome
CN102302552A (zh) * 2011-08-31 2012-01-04 朱明军 一种治疗心律失常的胶囊及其制备方法
WO2013053076A1 (en) 2011-10-10 2013-04-18 Zensun (Shanghai)Science & Technology Limited Compositions and methods for treating heart failure
JP6475623B2 (ja) 2012-10-08 2019-02-27 ゼンスン(シャンハイ)サイエンス アンド テクノロジー カンパニー リミテッド 糖尿病患者における心不全の治療用組成物
CA2911848A1 (en) 2013-05-22 2014-11-27 Zensun (Shanghai) Science & Technology, Ltd. Extended release of neuregulin for treating heart failure
SG11201600119PA (en) 2013-08-01 2016-02-26 Gilead Sciences Inc Compound and methods for treating long qt syndrome
CN104758300A (zh) 2014-01-02 2015-07-08 上海泽生科技开发有限公司 维生素d及其组合物的抗菌用途
CN110946993A (zh) 2014-01-03 2020-04-03 上海泽生科技开发股份有限公司 纽兰格林制剂的配方
CN105561298A (zh) 2014-10-17 2016-05-11 上海泽生科技开发有限公司 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130196911A1 (en) * 2010-03-24 2013-08-01 Massachusetts Institute Of Technology Methods and compositions for cardioprotection and cardioregeneration

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2822705C1 (ru) * 2023-11-03 2024-07-11 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ лечения некоронарогенной желудочковой парасистолии, регистрирующейся в покое

Also Published As

Publication number Publication date
AU2015320230A1 (en) 2017-03-30
CN105497876A (zh) 2016-04-20
EP3199174A1 (en) 2017-08-02
WO2016045493A1 (zh) 2016-03-31
CA2961813A1 (en) 2016-03-31
US10441633B2 (en) 2019-10-15
EP3199174B1 (en) 2022-04-13
RU2017113775A (ru) 2018-10-26
JP2017530127A (ja) 2017-10-12
EP3199174A4 (en) 2018-06-06
CN110337304A (zh) 2019-10-15
US20170368140A1 (en) 2017-12-28
RU2017113775A3 (enExample) 2019-04-04
KR20170055492A (ko) 2017-05-19
CN105497876B (zh) 2021-01-15

Similar Documents

Publication Publication Date Title
AU2015320230B2 (en) Uses of neuregulin in preventing, treating or delaying ventricular arrhythmia, and composition thereof
AU2021258063B2 (en) Methods and compositions of neuregulins for preventing, treating or delaying preserved ejection fraction cardiac failure
JP7761964B2 (ja) 心不全の治療用組成物
US20130079281A1 (en) Neuregulin based methods for treating heart failure
US20250262275A1 (en) Neuregulin based methods for treating heart failure
AU2021225283A1 (en) Method for preventing, treating or delaying heart failure by using neuregulin, and composition
CN117797243A (zh) 神经调节蛋白及其应用
HK40086556A (en) Method for preventing, treating or delaying heart failure by using neuregulin, and composition
HK1241737A1 (en) Compositions of a neuregulin for preventing, treating or delaying preserved ejection fraction cardiac failure
HK1241737B (en) Compositions of a neuregulin for preventing, treating or delaying preserved ejection fraction cardiac failure

Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY CO., LTD.

Free format text: FORMER NAME(S): ZENSUN (SHANGHAI) SCIENCE & TECHNOLOGY LIMITED

FGA Letters patent sealed or granted (standard patent)