JP2017529355A5 - - Google Patents
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- Publication number
- JP2017529355A5 JP2017529355A5 JP2017514874A JP2017514874A JP2017529355A5 JP 2017529355 A5 JP2017529355 A5 JP 2017529355A5 JP 2017514874 A JP2017514874 A JP 2017514874A JP 2017514874 A JP2017514874 A JP 2017514874A JP 2017529355 A5 JP2017529355 A5 JP 2017529355A5
- Authority
- JP
- Japan
- Prior art keywords
- hiv
- antibody
- molecule
- blood
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102100036011 T-cell surface glycoprotein CD4 Human genes 0.000 claims 3
- 108010041397 CD4 Antigens Proteins 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051200P | 2014-09-16 | 2014-09-16 | |
| US62/051,200 | 2014-09-16 | ||
| PCT/US2014/065048 WO2016043788A1 (en) | 2014-09-16 | 2014-11-11 | Treatment and functional cure of hiv infection by monoclonal antibodies to cd4 mediating competitive hiv entry inhibition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019199493A Division JP2020097569A (ja) | 2014-09-16 | 2019-11-01 | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017529355A JP2017529355A (ja) | 2017-10-05 |
| JP2017529355A5 true JP2017529355A5 (enExample) | 2017-12-21 |
| JP6716544B2 JP6716544B2 (ja) | 2020-07-01 |
Family
ID=55533661
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514874A Active JP6716544B2 (ja) | 2014-09-16 | 2014-11-11 | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
| JP2019199493A Pending JP2020097569A (ja) | 2014-09-16 | 2019-11-01 | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019199493A Pending JP2020097569A (ja) | 2014-09-16 | 2019-11-01 | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11180555B2 (enExample) |
| EP (1) | EP3194442A4 (enExample) |
| JP (2) | JP6716544B2 (enExample) |
| KR (1) | KR20170054478A (enExample) |
| CN (1) | CN107074944B (enExample) |
| AU (2) | AU2014406462A1 (enExample) |
| BR (1) | BR112017005134A2 (enExample) |
| CA (1) | CA2961464A1 (enExample) |
| MX (1) | MX2017003546A (enExample) |
| RU (1) | RU2762315C2 (enExample) |
| SG (1) | SG11201702056YA (enExample) |
| TW (1) | TWI695720B (enExample) |
| WO (1) | WO2016043788A1 (enExample) |
| ZA (1) | ZA201701856B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6716544B2 (ja) * | 2014-09-16 | 2020-07-01 | ユナイテッド・バイオメディカル・インコーポレーテッドUnited Biomedical Incorporated | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
| SG11201901203PA (en) * | 2016-08-13 | 2019-03-28 | United Biopharma Inc | Treatment and sustained virologic remission of hiv infection by antibodies to cd4 in haart stabilized patients |
| JP2021523929A (ja) * | 2018-03-05 | 2021-09-09 | オンコイミューン, インコーポレイテッド | 後天性免疫不全症候群(hiv/aids)の治療のための可溶性cd24の使用方法 |
| WO2021146272A1 (en) * | 2020-01-13 | 2021-07-22 | The Regents Of The University Of California | Methods for treating viral infections |
| CN116063506A (zh) * | 2022-09-02 | 2023-05-05 | 华道(上海)生物医药有限公司 | 一种分离的抗体及其用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4381295A (en) | 1979-04-26 | 1983-04-26 | Ortho Pharmaceutical Corporation | Monoclonal antibody to human helper T cells and methods of preparing same |
| DE3828582A1 (de) | 1988-08-23 | 1990-03-01 | Max Planck Gesellschaft | Monoklonaler antikoerper zur inhibierung der infektion von zellen durch hiv-viren |
| EP0365209A3 (en) | 1988-10-17 | 1990-07-25 | Becton, Dickinson and Company | Anti-leu 3a amino acid sequence |
| JPH0725794B2 (ja) | 1990-03-23 | 1995-03-22 | 呉羽化学工業株式会社 | 新規なペプチド |
| WO1992009305A1 (en) | 1990-11-27 | 1992-06-11 | Biogen, Inc. | Anti cd-4 antibodies blocking hiv-induced syncytia |
| CA2124967C (en) | 1991-12-17 | 2008-04-08 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| JPH06125783A (ja) | 1991-12-28 | 1994-05-10 | Chemo Sero Therapeut Res Inst | 組換え抗hiv抗体およびその調製方法 |
| EP0746613B1 (en) | 1994-03-08 | 2006-05-24 | Memorial Sloan-Kettering Cancer Center | Recombinant humanized anti-fb5 antibodies |
| US5961976A (en) | 1996-06-03 | 1999-10-05 | United Biomedical, Inc. | Antibodies against a host cell antigen complex for pre- and post-exposure protection from infection by HIV |
| JP3231262B2 (ja) | 1996-06-05 | 2001-11-19 | 株式会社ビー・エム・エル | ヒトTh1特異的タンパク質及びこれをコードする遺伝子、並びにこれに関連する形質転換体、組換えベクター及び抗体 |
| US5962319A (en) | 1997-05-19 | 1999-10-05 | Bml, Inc. | Human-Th1-specific protein, gene encoding the protein, transformants, recombinant vectors, and antibodies related to the gene |
| JPH10155489A (ja) | 1996-11-27 | 1998-06-16 | Asahi Chem Ind Co Ltd | 組換え抗体及びそれをコードする核酸 |
| GB2339430A (en) | 1997-05-21 | 2000-01-26 | Biovation Ltd | Method for the production of non-immunogenic proteins |
| US6051228A (en) * | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
| CN1307640A (zh) | 1998-05-25 | 2001-08-08 | 旭化成株式会社 | 细胞分离装置和分离方法 |
| US6090388A (en) | 1998-06-20 | 2000-07-18 | United Biomedical Inc. | Peptide composition for prevention and treatment of HIV infection and immune disorders |
| JP2000256211A (ja) | 1999-03-02 | 2000-09-19 | Schering Plough Corp | Hiv治療薬 |
| ES2301716T3 (es) | 2001-12-11 | 2008-07-01 | Biotectid Gmbh | Utilizacion de un ligando marcado con especificidad para la molecula de cd4 humana, para la preparacion de un agente de diagnostico destinado al analisis de modelos de migracion y/o distribucion de poblaciones de celulas. |
| JP2003327536A (ja) | 2002-03-07 | 2003-11-19 | Kitasato Inst:The | ヒト免疫不全症候群ウイルスの感染、増殖抑制剤 |
| US20030211470A1 (en) | 2002-03-15 | 2003-11-13 | Olson William C. | CD4-IgG2-based salvage therapy of HIV-1 infection |
| US7501494B2 (en) * | 2003-01-15 | 2009-03-10 | United Biomedical, Inc. | Designed deimmunized monoclonal antibodies for protection against HIV exposure and treatment of HIV infection |
| KR100633856B1 (ko) * | 2005-07-08 | 2006-10-13 | 조통래 | 산소와 오존을 함유한 미세기포가 녹아 있는 작물의병해충방제제 |
| WO2007094983A2 (en) * | 2006-02-03 | 2007-08-23 | Tanox, Inc. | Methods and compositions for the inhibition of hiv infection of t cells |
| US20130195881A1 (en) * | 2007-04-27 | 2013-08-01 | Sanjaya Singh | Potent, stable and non-immunosuppressive anti-cd4 antibodies |
| JP6716544B2 (ja) * | 2014-09-16 | 2020-07-01 | ユナイテッド・バイオメディカル・インコーポレーテッドUnited Biomedical Incorporated | 競合的hiv侵入阻害を媒介するcd4に対するモノクローナル抗体によるhiv感染の処置および機能的治癒 |
-
2014
- 2014-11-11 JP JP2017514874A patent/JP6716544B2/ja active Active
- 2014-11-11 US US15/512,043 patent/US11180555B2/en active Active
- 2014-11-11 CA CA2961464A patent/CA2961464A1/en active Pending
- 2014-11-11 BR BR112017005134A patent/BR112017005134A2/pt not_active IP Right Cessation
- 2014-11-11 CN CN201480081992.3A patent/CN107074944B/zh active Active
- 2014-11-11 MX MX2017003546A patent/MX2017003546A/es unknown
- 2014-11-11 EP EP14902149.5A patent/EP3194442A4/en not_active Ceased
- 2014-11-11 AU AU2014406462A patent/AU2014406462A1/en not_active Abandoned
- 2014-11-11 RU RU2017112967A patent/RU2762315C2/ru not_active Application Discontinuation
- 2014-11-11 KR KR1020177009857A patent/KR20170054478A/ko not_active Ceased
- 2014-11-11 WO PCT/US2014/065048 patent/WO2016043788A1/en not_active Ceased
- 2014-11-11 SG SG11201702056YA patent/SG11201702056YA/en unknown
-
2015
- 2015-09-16 TW TW104130548A patent/TWI695720B/zh active
-
2017
- 2017-03-15 ZA ZA2017/01856A patent/ZA201701856B/en unknown
-
2019
- 2019-11-01 JP JP2019199493A patent/JP2020097569A/ja active Pending
-
2021
- 2021-05-13 AU AU2021203071A patent/AU2021203071B2/en active Active
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