JP2017528158A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017528158A5 JP2017528158A5 JP2017524110A JP2017524110A JP2017528158A5 JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5 JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017524110 A JP2017524110 A JP 2017524110A JP 2017528158 A5 JP2017528158 A5 JP 2017528158A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- lentiviral vector
- vector
- antigen receptor
- chimeric antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156063A JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462028889P | 2014-07-25 | 2014-07-25 | |
| US62/028,889 | 2014-07-25 | ||
| US201562155811P | 2015-05-01 | 2015-05-01 | |
| US62/155,811 | 2015-05-01 | ||
| EP15306036.3 | 2015-06-29 | ||
| EP15306036 | 2015-06-29 | ||
| PCT/EP2015/067090 WO2016012623A1 (en) | 2014-07-25 | 2015-07-24 | Lentiviral vectors for regulated expression of a chimeric antigen receptor molecule |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Division JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528158A JP2017528158A (ja) | 2017-09-28 |
| JP2017528158A5 true JP2017528158A5 (cg-RX-API-DMAC7.html) | 2018-08-30 |
| JP6940406B2 JP6940406B2 (ja) | 2021-09-29 |
Family
ID=53514131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524110A Expired - Fee Related JP6940406B2 (ja) | 2014-07-25 | 2015-07-24 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020156063A Active JP7341110B2 (ja) | 2014-07-25 | 2020-09-17 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
| JP2023078059A Withdrawn JP2023113656A (ja) | 2014-07-25 | 2023-05-10 | キメラ抗原レセプター分子の制御的発現のためのレンチウイルスベクター |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10752668B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3511413B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6940406B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN107531800B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2956385A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016012623A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10228312B2 (en) | 2012-02-23 | 2019-03-12 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| WO2017068419A2 (en) * | 2015-10-22 | 2017-04-27 | Juno Therapeutics Gmbh | Methods, kits, agents and apparatuses for transduction |
| EP3443001B1 (en) | 2016-04-11 | 2025-04-30 | Obsidian Therapeutics, Inc. | REGULATED BIOCIRCUIT SYSTEMS |
| CN108276493B (zh) * | 2016-12-30 | 2023-11-14 | 南京传奇生物科技有限公司 | 一种嵌合抗原受体及其应用 |
| WO2018197949A1 (en) | 2017-04-27 | 2018-11-01 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| WO2018204352A1 (en) | 2017-05-01 | 2018-11-08 | The Trustees Of The University Of Pennsylvania | Monoclonal antibodies against alpha-synuclein fibrils |
| US20200283485A1 (en) | 2017-10-20 | 2020-09-10 | Institut Curie | Hook fusion protein for regulating the cellular trafficking of a target protein |
| US20200331975A1 (en) | 2017-10-20 | 2020-10-22 | Institut Curie | Dap10/12 based cars adapted for rush |
| CA3080109A1 (en) | 2017-11-03 | 2019-05-09 | Sorrento Therapeutics, Inc. | Cd38-directed chimeric antigen receptor constructs |
| EP3740199B1 (en) | 2018-01-17 | 2024-08-14 | Ixaka France | Polymer-encapsulated viral vectors for genetic therapy |
| EP3549597A1 (en) * | 2018-04-06 | 2019-10-09 | Heinrich-Heine-Universität Düsseldorf | Synthetic signalling constructs and its use |
| WO2019199689A1 (en) * | 2018-04-09 | 2019-10-17 | The Trustees Of The University Of Pennsylvania | Methods and compositions comprising a viral vector for expression of a transgene and an effector |
| US12215337B2 (en) | 2018-04-12 | 2025-02-04 | Umoja Biopharma, Inc. | Viral vectors and packaging cell lines |
| US12319745B2 (en) | 2019-07-16 | 2025-06-03 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Antibodies having specificity for CD38 and uses thereof |
| AU2020345943A1 (en) | 2019-09-10 | 2022-03-31 | Obsidian Therapeutics, Inc. | CA2-IL15 fusion proteins for tunable regulation |
| GB201914611D0 (en) * | 2019-10-09 | 2019-11-20 | Autolus Ltd | Engineered immune cell |
| US20230085724A1 (en) | 2020-03-05 | 2023-03-23 | Neotx Therapeutics Ltd. | Methods and compositions for treating cancer with immune cells |
| AU2021337534A1 (en) * | 2020-09-01 | 2023-03-16 | The Trustees Of The University Of Pennsylvania | Improved generation of lentiviral vectors for T cell transduction using cocal envelope |
| JP2023554542A (ja) | 2020-11-13 | 2023-12-27 | ホーニング バイオサイエンシズ | 目的の分泌性タンパク質または細胞膜固定タンパク質の細胞内輸送を制御するための手段および方法 |
| IT202100011576A1 (it) * | 2021-05-06 | 2022-11-06 | Univ Degli Studi Padova | Nuova sequenza promotore per terapia genica |
| KR20240124919A (ko) | 2021-11-15 | 2024-08-19 | 떼라벡띠스 | 인유두종 바이러스 항원의 발현을 위한 렌티바이러스 벡터 및 이의 hpv 유발 암 치료에 대한 구현 |
| CA3256704A1 (en) * | 2022-05-23 | 2023-11-30 | The Broad Institute, Inc. | METHODS AND COMPOSITIONS FOR CRISPR SCREENING OF IMMUNE CELLS |
| WO2024023135A1 (en) | 2022-07-27 | 2024-02-01 | Theravectys | Lentiviral vectors for expression of human papillomavirus (hpv) antigens and its implementation in the treatment of hpv induced cancers |
| US20250025168A1 (en) | 2023-07-21 | 2025-01-23 | Cilag Gmbh International | Systems and subsystems for firing a surgical instrument |
| EP4624494A1 (en) | 2024-03-29 | 2025-10-01 | Institut Curie | Her2 single domain antibody and uses thereof |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| WO1987002671A1 (en) | 1985-11-01 | 1987-05-07 | International Genetic Engineering, Inc. | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE68927933T2 (de) | 1988-09-02 | 1997-08-14 | Dyax Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| AU665190B2 (en) | 1990-07-10 | 1995-12-21 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1992003918A1 (en) | 1990-08-29 | 1992-03-19 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| DK0564531T3 (da) | 1990-12-03 | 1998-09-28 | Genentech Inc | Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber |
| DK1279731T3 (da) | 1991-03-01 | 2007-09-24 | Dyax Corp | Fremgangsmåde til udvikling af bindende miniproteiner |
| DK1471142T3 (da) | 1991-04-10 | 2009-03-09 | Scripps Research Inst | Heterodimere receptor-biblioteker under anvendelse af fagemider |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| DE4135543A1 (de) | 1991-10-28 | 1993-04-29 | Boehringer Mannheim Gmbh | Rekombinantes core-streptavidin |
| JP2003517274A (ja) * | 1998-10-05 | 2003-05-27 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | 癌関連抗原およびその使用 |
| EP2169073B1 (en) | 1999-10-11 | 2013-11-13 | Institut Pasteur | Vector for the preparation of immunotherapeutical compositions |
| US6841359B2 (en) * | 2000-10-31 | 2005-01-11 | The General Hospital Corporation | Streptavidin-binding peptides and uses thereof |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| JP2005507236A (ja) * | 2001-04-03 | 2005-03-17 | キュラジェン コーポレイション | 抗原性ポリペプチドに結合する新規抗体、抗原をコードする核酸、および使用方法 |
| AU2002307625A1 (en) * | 2002-03-08 | 2003-09-22 | Cueros Industrializados Del Bajio | Method of incorporating heat-stable particles into leather |
| US20050032173A1 (en) * | 2003-08-05 | 2005-02-10 | Mauricio Rojas | Fusion proteins with a membrane translocating sequence and methods of using same to inhibit an immune response |
| US20130266551A1 (en) * | 2003-11-05 | 2013-10-10 | St. Jude Children's Research Hospital, Inc. | Chimeric receptors with 4-1bb stimulatory signaling domain |
| US7265205B2 (en) * | 2005-02-11 | 2007-09-04 | Uti Limited Partnership | Monomeric streptavidin muteins |
| JP2009529917A (ja) * | 2006-03-22 | 2009-08-27 | ヴァイラル ロジック システムズ テクノロジー コーポレーション | 標的ポリペプチドの同定方法および免疫学的疾患の治療のためのその使用 |
| JP2010509233A (ja) * | 2006-11-03 | 2010-03-25 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 新規ｓＥＨ阻害剤およびそれらの使用 |
| EP2147683A1 (en) | 2008-07-25 | 2010-01-27 | DKFZ Deutsches Krebsforschungszentrum | Construct and method for the internalization of cargo molecules into a cell |
| WO2010142785A1 (en) * | 2009-06-11 | 2010-12-16 | Institut Curie | Methods and kits for regulating intracellular trafficking of a target protein |
| EP2651442B1 (en) * | 2010-12-14 | 2020-04-22 | University of Maryland, Baltimore | Universal anti-tag chimeric antigen receptor-expressing t cells and methods of treating cancer |
| SG194099A1 (en) * | 2011-04-15 | 2013-11-29 | Compugen Ltd | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| SG11201404769UA (en) * | 2012-02-22 | 2014-11-27 | Univ Pennsylvania | Use of icos-based cars to enhance antitumor activity and car persistence |
| SMT202100005T1 (it) * | 2012-08-20 | 2021-05-07 | Hutchinson Fred Cancer Res | Metodo e composizioni per immunoterapia cellulare |
| CA2886684C (en) | 2012-10-10 | 2023-09-19 | Sangamo Biosciences, Inc. | T cell modifying compounds and uses thereof |
| CA2933707A1 (en) * | 2013-12-20 | 2015-06-25 | Fred Hutchinson Cancer Research Center | Tagged chimeric effector molecules and receptors thereof |
| GB2592821B (en) * | 2015-07-31 | 2022-01-12 | Univ Minnesota | Modified cells and methods of therapy |
-
2015
- 2015-07-24 WO PCT/EP2015/067090 patent/WO2016012623A1/en not_active Ceased
- 2015-07-24 CN CN201580051938.9A patent/CN107531800B/zh active Active
- 2015-07-24 CA CA2956385A patent/CA2956385A1/en active Pending
- 2015-07-24 EP EP19159129.6A patent/EP3511413B1/en active Active
- 2015-07-24 US US15/327,517 patent/US10752668B2/en active Active
- 2015-07-24 CN CN202110939899.3A patent/CN113846062B/zh active Active
- 2015-07-24 EP EP15742027.4A patent/EP3172228B1/en active Active
- 2015-07-24 JP JP2017524110A patent/JP6940406B2/ja not_active Expired - Fee Related
-
2020
- 2020-07-17 US US16/931,986 patent/US20210009653A1/en not_active Abandoned
- 2020-09-17 JP JP2020156063A patent/JP7341110B2/ja active Active
-
2023
- 2023-05-10 JP JP2023078059A patent/JP2023113656A/ja not_active Withdrawn