JP2017527557A5 - - Google Patents

Download PDF

Info

Publication number
JP2017527557A5
JP2017527557A5 JP2017510880A JP2017510880A JP2017527557A5 JP 2017527557 A5 JP2017527557 A5 JP 2017527557A5 JP 2017510880 A JP2017510880 A JP 2017510880A JP 2017510880 A JP2017510880 A JP 2017510880A JP 2017527557 A5 JP2017527557 A5 JP 2017527557A5
Authority
JP
Japan
Prior art keywords
seq
protein
mva vector
recombinant
recombinant mva
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017510880A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017527557A (ja
JP6823586B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2015/070161 external-priority patent/WO2016034678A2/en
Publication of JP2017527557A publication Critical patent/JP2017527557A/ja
Publication of JP2017527557A5 publication Critical patent/JP2017527557A5/ja
Application granted granted Critical
Publication of JP6823586B2 publication Critical patent/JP6823586B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017510880A 2014-09-03 2015-09-03 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン Active JP6823586B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462045538P 2014-09-03 2014-09-03
US62/045,538 2014-09-03
US201462055154P 2014-09-25 2014-09-25
US62/055,154 2014-09-25
PCT/EP2015/070161 WO2016034678A2 (en) 2014-09-03 2015-09-03 Recombinant modified vaccinia virus ankara (mva) filovirus vaccine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021000975A Division JP7113924B2 (ja) 2014-09-03 2021-01-06 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン

Publications (3)

Publication Number Publication Date
JP2017527557A JP2017527557A (ja) 2017-09-21
JP2017527557A5 true JP2017527557A5 (https=) 2018-10-11
JP6823586B2 JP6823586B2 (ja) 2021-02-03

Family

ID=54145734

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017510880A Active JP6823586B2 (ja) 2014-09-03 2015-09-03 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン
JP2021000975A Active JP7113924B2 (ja) 2014-09-03 2021-01-06 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021000975A Active JP7113924B2 (ja) 2014-09-03 2021-01-06 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン

Country Status (14)

Country Link
US (2) US10576141B2 (https=)
EP (1) EP3188752A2 (https=)
JP (2) JP6823586B2 (https=)
KR (2) KR102736868B1 (https=)
CN (2) CN106999565B (https=)
AU (2) AU2015310909B2 (https=)
CA (1) CA2959105C (https=)
IL (2) IL250552B (https=)
MX (1) MX2017002791A (https=)
MY (1) MY193417A (https=)
SG (2) SG11201701506PA (https=)
UA (1) UA126848C2 (https=)
WO (1) WO2016034678A2 (https=)
ZA (1) ZA201701077B (https=)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10130697B2 (en) 2010-03-23 2018-11-20 Wisconsin Alumni Research Foundation (Warf) Vaccines comprising mutant attenuated influenza viruses
ES2655051T3 (es) 2011-08-26 2018-02-16 Wisconsin Alumni Research Foundation Virus de la gripe con segmento génico PB2 mutante como vacunas vivas atenuadas
WO2015196150A2 (en) 2014-06-20 2015-12-23 Wisconsin Alumni Research Foundation (Warf) Mutations that confer genetic stability to additional genes in influenza viruses
HUE040440T2 (hu) 2014-11-04 2019-03-28 Janssen Vaccines & Prevention Bv Terápiás HPV16-oltóanyagok
EP3223723B1 (en) * 2014-11-26 2020-01-08 Neuravi Limited A clot retrieval device for removing occlusive clot from a blood vessel
US11701418B2 (en) * 2015-01-12 2023-07-18 Geovax, Inc. Replication-deficient modified vaccinia Ankara (MVA) expressing Ebola virus glycoprotein (GP) and matrix protein (VP40)
EP4122492A1 (en) * 2015-02-25 2023-01-25 Memorial Sloan Kettering Cancer Center Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors
EP3283508B1 (en) 2015-04-17 2021-03-17 Alpine Immune Sciences, Inc. Immunomodulatory proteins with tunable affinities
EP3402802B1 (en) * 2016-01-08 2023-04-12 Geovax, Inc. Compositions and methods for generating an immune response to a tumor associated antigen
BR112018015696A2 (pt) 2016-02-03 2018-12-26 Geovax Inc composições e métodos para gerar uma resposta imune para um flavivírus
CA3014435C (en) 2016-02-19 2023-04-18 Wisconsin Alumni Research Foundation (Warf) Improved influenza b virus replication for vaccine development
EP4706777A2 (en) 2016-04-15 2026-03-11 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
IL262365B2 (en) 2016-04-15 2024-11-01 Alpine Immune Sciences Inc Immunomodulatory proteins ICOS ligand variants and uses thereof
EP3452087A1 (en) * 2016-05-02 2019-03-13 Janssen Vaccines & Prevention B.V. Therapeutic hpv vaccine combinations
EP3484507A1 (en) 2016-07-15 2019-05-22 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against a marburg virus infection
US11834490B2 (en) 2016-07-28 2023-12-05 Alpine Immune Sciences, Inc. CD112 variant immunomodulatory proteins and uses thereof
CA3040296A1 (en) * 2016-10-20 2018-04-26 Alpine Immune Sciences, Inc. Secretable variant immunomodulatory proteins and engineered cell therapy
JP2020511144A (ja) 2017-03-16 2020-04-16 アルパイン イミューン サイエンシズ インコーポレイテッド Pd−l2バリアント免疫調節タンパク質及びその使用
EP3596114A2 (en) 2017-03-16 2020-01-22 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
US11173204B2 (en) 2017-04-06 2021-11-16 Janssen Vaccines & Prevention B.V. MVA-BN and Ad26.ZEBOV or Ad26.filo prime-boost regimen
CN110603058A (zh) 2017-05-15 2019-12-20 扬森疫苗与预防公司 含有病毒的稳定组合物
KR102658198B1 (ko) 2017-05-15 2024-04-16 얀센 백신스 앤드 프리벤션 비.브이. 안정한 바이러스 함유 조성물
WO2019018501A1 (en) * 2017-07-18 2019-01-24 Geovax Inc. COMPOSITIONS AND METHODS FOR GENERATING LASV IMMUNE RESPONSE
US11311612B2 (en) 2017-09-19 2022-04-26 Geovax, Inc. Compositions and methods for generating an immune response to treat or prevent malaria
GB201716181D0 (en) * 2017-10-04 2017-11-15 Univ Cape Town Recombinant mva with modified hiv-1 env
KR102813968B1 (ko) 2017-10-10 2025-05-29 알파인 이뮨 사이언시즈, 인코포레이티드 Ctla-4 변이체 면역조절 단백질 및 이의 용도
SMT202600062T1 (it) 2017-10-18 2026-03-09 Alpine Immune Sciences Inc Proteine immunomodulatrici del ligando di icos variante e composizioni e metodi correlati
WO2019084310A1 (en) 2017-10-25 2019-05-02 Yoshihiro Kawaoka HAS RECOMBINANT INFLUENZA VIRUSES STABILIZED FOR EGG REPLICATION
SG11202006148UA (en) 2018-01-03 2020-07-29 Alpine Immune Sciences Inc Multi-domain immunomodulatory proteins and methods of use thereof
US12343390B2 (en) * 2018-08-07 2025-07-01 Wisconsin Alumni Research Foundation (Warf) Recombinant biologically contained filovirus vaccine
JP7655849B2 (ja) 2018-08-20 2025-04-02 ウィスコンシン アルムニ リサーチ ファンデイション ヘマグルチニン(ha)タンパク質内の非ドミナントエピトープに対する免疫応答を誘起するためのベクター
EP3847246A1 (en) 2018-09-06 2021-07-14 Bavarian Nordic A/S Storage improved poxvirus compositions
CN121499810A (zh) * 2018-09-28 2026-02-10 剑桥企业有限公司 疫苗和方法
WO2020113141A2 (en) 2018-11-30 2020-06-04 Alpine Immune Sciences, Inc. Cd86 variant immunomodulatory proteins and uses thereof
WO2020163804A1 (en) 2019-02-08 2020-08-13 Wisconsin Alumni Research Foundation (Warf) Humanized cell line
US11390649B2 (en) 2019-05-01 2022-07-19 Wisconsin Alumni Research Foundation (Warf) Influenza virus replication for vaccine development
US11807872B2 (en) 2019-08-27 2023-11-07 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized HA for replication in eggs
WO2021150874A1 (en) 2020-01-24 2021-07-29 Wisconsin Alumni Research Foundation (Warf) Recombinant influenza viruses with stabilized na
JP2023513611A (ja) 2020-02-14 2023-03-31 ゲオバックス インコーポレイテッド Sars-cov2に対する免疫応答を誘導するためのワクチン及びその利用
US20230114464A1 (en) 2020-03-12 2023-04-13 Bavarian Nordic A/S Conditions Improving Poxvirus Stability
US12290562B2 (en) 2020-03-25 2025-05-06 Wisconsin Alumni Research Foundation (Warf) Recombinant multivalent influenza viruses
CN115819616B (zh) * 2021-07-28 2025-04-11 江苏瑞科生物技术股份有限公司 一种基因重组vzv融合蛋白及其制备方法和应用
EP4677076A1 (en) 2023-03-10 2026-01-14 Bavarian Nordic A/S Methods of isolating poxviruses from avian cell cultures
AU2024234386A1 (en) 2023-03-10 2025-08-28 Bavarian Nordic A/S Production of poxviruses from quail cell cultures
WO2024188801A1 (en) 2023-03-10 2024-09-19 Bavarian Nordic A/S Use of quail cell lines for poxvirus production
WO2026006679A1 (en) * 2024-06-28 2026-01-02 The Regents Of The University Of California Retroviral vectors
CN120795167A (zh) * 2025-04-15 2025-10-17 佰芮慷(广州)细胞医药科技有限公司 一种靶向人eb病毒的嵌合抗原受体car、car-nk细胞及用途
CN120843742A (zh) * 2025-09-09 2025-10-28 军事科学院军事医学研究院军事兽医研究所 一种泛哺乳动物丝状病毒检测用引物组及其检测试剂盒和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003028632A2 (en) * 2001-10-01 2003-04-10 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Development of a preventive vaccine for filovirus infection in primates
EP1586331B1 (en) * 2001-10-01 2008-05-28 The Government of the U.S.A., as repr. by the Secretary, Dept. of Health & Human Services, the Nat. Inst. of Health Development of a preventive vaccine for filovirus infection in primates
WO2004042001A2 (en) * 2002-05-17 2004-05-21 Emory University Virus-like particles, methods of preparation, and immonogenic compositions
AU2005289439B2 (en) * 2004-09-27 2011-12-01 Crucell Holland B.V. Optimized vaccines to provide protection against Ebola and other viruses
GB0706912D0 (en) * 2007-04-10 2007-05-16 Isis Innovation Novel viral vaccines
CA2741523C (en) * 2008-10-24 2022-06-21 Jonathan S. Towner Human ebola virus species and compositions and methods thereof
CN102325888B (zh) 2008-11-21 2016-09-07 巴法里安诺迪克有限公司 包含多个同源核苷酸序列的载体
US9097713B2 (en) * 2009-09-02 2015-08-04 The United States Of America As Represented By The Secretary Of The Army On Behalf Of Usamrmc Monoclonal antibodies against glycoprotein of Ebola sudan boniface virus
EP2560680B1 (en) * 2010-04-16 2018-11-28 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Chimpanzee adenoviral vector-based filovirus vaccines
CA3194125A1 (en) * 2012-04-12 2013-10-17 The Trustees Of The University Of Pennsylvania Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
WO2014037124A1 (en) * 2012-09-04 2014-03-13 Bavarian Nordic A/S Methods and compositions for enhancing vaccine immune responses
GB201303406D0 (en) 2013-02-26 2013-04-10 Health Prot Agency Crimean-Congo Haemorrhagic Fever Virus Antigenic Composition

Similar Documents

Publication Publication Date Title
JP2017527557A5 (https=)
JP7113924B2 (ja) 組み換え改変ワクシニアウイルスアンカラ(mva)フィロウイルスワクチン
Vrba et al. Development and applications of viral vectored vaccines to combat zoonotic and emerging public health threats
Lauer et al. Multivalent and multipathogen viral vector vaccines
Sánchez-Sampedro et al. The evolution of poxvirus vaccines
Liniger et al. Use of viral vectors for the development of vaccines
Tatsis et al. Adenoviruses as vaccine vectors
Kittel et al. Generation of an influenza A virus vector expressing biologically active human interleukin-2 from the NS gene segment
US11896657B2 (en) Replication-deficient modified vaccinia Ankara (MVA) expressing Marburg virus glycoprotein (GP) and matrix protein (VP40)
Kaynarcalidan et al. Vaccinia virus: from crude smallpox vaccines to elaborate viral vector vaccine design
HRP20221474T1 (hr) Cjepiva protiv virusa hepatitisa b
JP2017515508A5 (https=)
Khattar et al. Mucosal immunization with Newcastle disease virus vector coexpressing HIV-1 Env and Gag proteins elicits potent serum, mucosal, and cellular immune responses that protect against vaccinia virus Env and Gag challenges
WO2012053646A1 (ja) ワクシニアウイルスベクターおよびセンダイウイルスベクターからなるプライム/ブーストワクチン用ウイルスベクター
US20240392257A1 (en) Utilization of Micro-RNA for Downregulation of Cytotoxic Transgene Expression by Modified Vaccinia Virus Ankara (MVA)
Nakaya et al. Induction of cellular immune responses to simian immunodeficiency virus gag by two recombinant negative-strand RNA virus vectors
JP5675789B2 (ja) 免疫接種のための発現ベクターとしての水疱性口内炎ウイルスの異なる複数の抗原型
Medina et al. Virulence and immune evasion strategies of FMDV: implications for vaccine design
Allen et al. mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020
Lawrence et al. Comparison of heterologous prime-boost strategies against human immunodeficiency virus type 1 Gag using negative stranded RNA viruses
Di et al. The self-assembled nanoparticle-based multi-epitope influenza mRNA vaccine elicits protective immunity against H1N1 and B influenza viruses in mice
US20230126396A1 (en) Compositions and Administration of Chimeric Glycoprotein Lyssavirus Vaccines for Coverage Against Rabies
Mayrhofer et al. Nonreplicating vaccinia virus vectors expressing the H5 influenza virus hemagglutinin produced in modified Vero cells induce robust protection
RU2020125098A (ru) Рекомбинантные вирусоподобные частицы (vlp) с использованием протеина группового антигена (gag) вируса бычьего иммунодефицита
WO2009090594A2 (en) Alphavirus based vectors