JP2017527299A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017527299A5 JP2017527299A5 JP2017514828A JP2017514828A JP2017527299A5 JP 2017527299 A5 JP2017527299 A5 JP 2017527299A5 JP 2017514828 A JP2017514828 A JP 2017514828A JP 2017514828 A JP2017514828 A JP 2017514828A JP 2017527299 A5 JP2017527299 A5 JP 2017527299A5
- Authority
- JP
- Japan
- Prior art keywords
- curved
- inlet
- microfluidic system
- microchannel
- outlets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051497P | 2014-09-17 | 2014-09-17 | |
| US62/051,497 | 2014-09-17 | ||
| PCT/US2015/050604 WO2016044537A1 (en) | 2014-09-17 | 2015-09-17 | Microfluidic system and method for perfusion bioreactor cell retention |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017527299A JP2017527299A (ja) | 2017-09-21 |
| JP2017527299A5 true JP2017527299A5 (enExample) | 2018-10-25 |
Family
ID=55533830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514828A Pending JP2017527299A (ja) | 2014-09-17 | 2015-09-17 | 灌流バイオリアクター細胞保持のためのマイクロ流体システム及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170292104A1 (enExample) |
| EP (1) | EP3194560A4 (enExample) |
| JP (1) | JP2017527299A (enExample) |
| CN (1) | CN107250341A (enExample) |
| WO (1) | WO2016044537A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6265508B2 (ja) | 2012-09-21 | 2018-01-24 | マサチューセッツ インスティテュート オブ テクノロジー | マイクロ流体装置およびその使用 |
| US10047344B2 (en) | 2014-02-18 | 2018-08-14 | National University Of Singapore | Biophysically sorted osteoprogenitors from culture expanded bone marrow derived mesenchymal stromal cells (MSCs) |
| WO2016044555A1 (en) | 2014-09-17 | 2016-03-24 | Massachusetts Institute Of Technology | System and method for inertial focusing microfiltration for intra-operative blood salvage autotransfusion |
| JP6912161B2 (ja) * | 2016-02-25 | 2021-07-28 | 株式会社神戸製鋼所 | 流路装置及び液滴形成方法 |
| CN109475868B (zh) * | 2016-07-21 | 2021-08-17 | 新加坡科技研究局 | 用于高体积分数颗粒微滤的外壁聚焦的设备及其制造方法 |
| US10697871B2 (en) | 2016-10-07 | 2020-06-30 | Massachusetts Institute Of Technology | Particle isolation/enrichment using continuous closed-loop micro-fluidics |
| WO2018093475A1 (en) * | 2016-11-15 | 2018-05-24 | Massachusetts Institute Of Technology | Liquid biopsy detection of leukemia using closed-loop microfluidics |
| TWI728225B (zh) * | 2017-01-25 | 2021-05-21 | 英屬開曼群島商鴻騰精密科技股份有限公司 | 微流體盒及其堆疊測試組件 |
| KR101901672B1 (ko) | 2017-01-25 | 2018-10-25 | 주식회사 디오스템스 | 줄기세포 배양기 및 배양 방법, 줄기세포 연속 배양, 추출 및 분리 시스템 및 방법 |
| JP2020513798A (ja) * | 2017-03-17 | 2020-05-21 | イスタンブール・テクニック・ユニヴェルシテシＩｓｔａｎｂｕｌ Ｔｅｋｎｉｋ Ｕｎｉｖｅｒｓｉｔｅｓｉ | ガン細胞の血液からの連続的分離および循環系でのその豊富化のための非対称カールにより構成されるらせん形状を有するマイクロチャネル |
| CN106994369A (zh) * | 2017-05-22 | 2017-08-01 | 东南大学 | 通量可调控的微流控集成器件及其制作方法 |
| JP7124475B2 (ja) * | 2018-01-17 | 2022-08-24 | 株式会社Ihi | 細胞培養システム及び細胞培養方法 |
| CN108517284A (zh) * | 2018-03-19 | 2018-09-11 | 复旦大学 | 一种用于研究藻类生长和生殖的微流控芯片 |
| TWI846694B (zh) | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| WO2019226618A1 (en) * | 2018-05-22 | 2019-11-28 | Nantkwest, Inc. | Methods and systems for cell bed formation during bioprocessing |
| EP4477315A3 (en) | 2018-05-31 | 2025-03-05 | Donaldson Company, Inc. | Droplet sensors for fuel systems |
| JP7087704B2 (ja) * | 2018-06-13 | 2022-06-21 | 株式会社Ihi | 細胞培養システム及び細胞培養方法 |
| WO2019245070A1 (ko) * | 2018-06-20 | 2019-12-26 | 주식회사 디오스템스 | 줄기세포 증식기 및 증식 방법, 줄기세포 연속 증식, 추출 및 분리 시스템 및 방법 |
| US12042792B2 (en) | 2018-11-15 | 2024-07-23 | Massachusetts Institute Of Technology | Multi-dimensional double spiral device and methods of use thereof |
| JP2021013333A (ja) * | 2019-07-12 | 2021-02-12 | 株式会社Ihi | 微生物選別システム及び微生物選別方法 |
| ES3009703T3 (en) * | 2019-11-29 | 2025-03-31 | Donaldson Co Inc | Systems and methods for separating particles in fluids |
| CN111774103B (zh) * | 2020-06-01 | 2021-09-07 | 东南大学 | 一种高通量血浆分离的多核螺旋惯性分选微流控器件 |
| SE544733C2 (en) * | 2020-07-20 | 2022-10-25 | Javier Cruz | Microfluidic device and method for manipulation of particles in fluids |
| US20240002772A1 (en) * | 2020-10-13 | 2024-01-04 | Boehringer Ingelheim International Gmbh | Systems and methods for producing a biologic molecule with hydrocyclone cell retention device |
| KR102474060B1 (ko) * | 2020-10-14 | 2022-12-05 | 한국과학기술연구원 | 미세유체칩 유동에 의한 세포입자의 크기별 분리 장치와 방법 |
| KR20230108294A (ko) * | 2020-11-25 | 2023-07-18 | 도날드슨 컴파니, 인코포레이티드 | 최적의 미세채널 길이를 갖는 수리동력학적 분리기 |
| US12478899B2 (en) | 2021-06-02 | 2025-11-25 | Donaldson Company, Inc. | Maintenance of hydrodynamic separators |
| US12252678B2 (en) | 2021-12-01 | 2025-03-18 | Microfluidx Ltd | Systems and methods for bioprocessing |
| CN114260037B (zh) * | 2021-12-27 | 2023-02-03 | 杭州电子科技大学 | 一种3d堆叠式多级惯性微流控分选芯片及其制备方法 |
| WO2023211901A1 (en) | 2022-04-28 | 2023-11-02 | Massachusetts Institute Of Technology | Spiral inertial microfluidic devices and methods to remove contaminants |
| CN114813466B (zh) * | 2022-05-05 | 2025-02-18 | 山东大学 | 一种预测水力旋流器分选细胞活性的方法及系统 |
| EP4591989A1 (en) * | 2022-09-21 | 2025-07-30 | Canon Kabushiki Kaisha | Microchannel device, separation device, and separation method |
| CN120586947A (zh) * | 2025-04-28 | 2025-09-05 | 华北理工大学 | 收集汗液的微流控平台 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8931644B2 (en) * | 2006-11-30 | 2015-01-13 | Palo Alto Research Center Incorporated | Method and apparatus for splitting fluid flow in a membraneless particle separation system |
| US9486812B2 (en) * | 2006-11-30 | 2016-11-08 | Palo Alto Research Center Incorporated | Fluidic structures for membraneless particle separation |
| US8186913B2 (en) * | 2007-04-16 | 2012-05-29 | The General Hospital Corporation | Systems and methods for particle focusing in microchannels |
| WO2010115025A2 (en) * | 2009-04-01 | 2010-10-07 | University Of Louisville Research Foundation, Inc. | Device and methods for isolating cells |
| SG183468A1 (en) * | 2010-03-04 | 2012-09-27 | Univ Singapore | Microfluidics sorter for cell detection and isolation |
| CA2861270C (en) * | 2012-01-18 | 2021-08-03 | Bayer Healthcare Llc | Perfusion bioreactor systems comprising a cell aggregate trap and methods of operating the same |
| WO2013116696A1 (en) * | 2012-02-03 | 2013-08-08 | University Of Cincinnati | Microfluidic methods for passive separation of cells and particles |
| US9416344B2 (en) * | 2012-03-15 | 2016-08-16 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| WO2013144253A1 (en) * | 2012-03-29 | 2013-10-03 | Arizona Board Of Regents On Behalf University Of Arizona | Cell culture apparatus and culture methods using same |
| JP6265508B2 (ja) * | 2012-09-21 | 2018-01-24 | マサチューセッツ インスティテュート オブ テクノロジー | マイクロ流体装置およびその使用 |
| JP6501709B2 (ja) * | 2012-09-28 | 2019-04-17 | キヤノン ユー．エス． ライフ サイエンシズ， インコーポレイテッドＣａｎｏｎ Ｕ．Ｓ． Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． | スパイラル慣性濾過を使用する粒子分離及び濃縮 |
| US20140093952A1 (en) * | 2012-10-02 | 2014-04-03 | David Serway | Bioreactor Tangential Flow Perfusion Filter System |
| CN103981093B (zh) * | 2014-04-24 | 2017-01-04 | 上海泰因生物技术有限公司 | 一种用生物反应器进行细胞特性筛选的装置与方法 |
-
2015
- 2015-09-17 JP JP2017514828A patent/JP2017527299A/ja active Pending
- 2015-09-17 CN CN201580062211.0A patent/CN107250341A/zh active Pending
- 2015-09-17 WO PCT/US2015/050604 patent/WO2016044537A1/en not_active Ceased
- 2015-09-17 US US15/512,003 patent/US20170292104A1/en not_active Abandoned
- 2015-09-17 EP EP15841214.8A patent/EP3194560A4/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017527299A5 (enExample) | ||
| US10502668B2 (en) | Method of collecting target cells | |
| Warkiani et al. | Large-volume microfluidic cell sorting for biomedical applications | |
| US10583438B2 (en) | Combined sorting and concentrating particles in a microfluidic device | |
| CN108495809B (zh) | 使用微流体装置的多段式靶细胞富集 | |
| KR101662808B1 (ko) | 나선형 분지채널을 이용한 미세유체칩 여과 장치 및 방법 | |
| WO2019117800A1 (en) | Microfluidic device and method for cell separation of a blood sample | |
| JP2015529155A5 (enExample) | ||
| CN102743974A (zh) | 海水淡化系统及能量交换腔 | |
| WO2012097450A1 (en) | Apparatus and method for particle separation | |
| US20200238217A1 (en) | Peristaltic Pump Microfluidic Separator | |
| ES2918374T3 (es) | Dispositivo de filtración de fluidos y ensamblaje | |
| JP2020099256A (ja) | 分離方法 | |
| Yin et al. | Highly efficient capture of circulating tumor cells with low background signals by using pyramidal microcavity array | |
| CN106794423B (zh) | 海水淡化系统及能量回收装置 | |
| EP2196253A3 (en) | Membrane container | |
| EP2809417B1 (en) | Wastewater treatment plant | |
| Bayareh et al. | Cancer cell separation using passive mechanisms: A review | |
| CN214781742U (zh) | 一种微流控芯片盒 | |
| CN104388299B (zh) | 一种用于细胞捕获的微流控芯片 | |
| EP3897982B1 (en) | Microfluidic device | |
| CN102989256B (zh) | 一种多级过滤器 | |
| JP2012194047A (ja) | 液体クロマトグラフィー装置及び充填剤の充填方法 | |
| CN112385645A (zh) | 一种多级添加细胞低温保护剂的上层芯片和微装置 | |
| CN106552444B (zh) | 一种t型双液相分离装置及其使用方法 |