JP2017525972A - グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価 - Google Patents

グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価 Download PDF

Info

Publication number
JP2017525972A
JP2017525972A JP2017511664A JP2017511664A JP2017525972A JP 2017525972 A JP2017525972 A JP 2017525972A JP 2017511664 A JP2017511664 A JP 2017511664A JP 2017511664 A JP2017511664 A JP 2017511664A JP 2017525972 A JP2017525972 A JP 2017525972A
Authority
JP
Japan
Prior art keywords
globin
glucosylated
diabetes
hemoglobin
glycosylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017511664A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017525972A5 (enExample
Inventor
クルーゼ アイルズ,レイモンド
クルーゼ アイルズ,レイモンド
Original Assignee
マップ アイピー ホールディング リミテッド
マップ アイピー ホールディング リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マップ アイピー ホールディング リミテッド, マップ アイピー ホールディング リミテッド filed Critical マップ アイピー ホールディング リミテッド
Publication of JP2017525972A publication Critical patent/JP2017525972A/ja
Publication of JP2017525972A5 publication Critical patent/JP2017525972A5/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/723Glycosylated haemoglobin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/042Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2017511664A 2014-08-29 2015-08-27 グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価 Pending JP2017525972A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1415369.6 2014-08-29
GBGB1415369.6A GB201415369D0 (en) 2014-08-29 2014-08-29 Rapid screening and evaluation of diabetes and prediabetes by glycated haemoglobin mass spectrometry
PCT/GB2015/052487 WO2016030687A1 (en) 2014-08-29 2015-08-27 Rapid screening and evaluation of diabetes and prediabetes by glycated hemoglobin mass spectrometry.

Publications (2)

Publication Number Publication Date
JP2017525972A true JP2017525972A (ja) 2017-09-07
JP2017525972A5 JP2017525972A5 (enExample) 2018-10-04

Family

ID=51752373

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017511664A Pending JP2017525972A (ja) 2014-08-29 2015-08-27 グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価

Country Status (6)

Country Link
US (1) US10161941B2 (enExample)
EP (1) EP3186641B1 (enExample)
JP (1) JP2017525972A (enExample)
CN (1) CN107209189B (enExample)
GB (1) GB201415369D0 (enExample)
WO (1) WO2016030687A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021535380A (ja) * 2018-08-22 2021-12-16 クエスト ダイアグノスティクス インベストメンツ エルエルシー 糖尿病におけるマイクロサンプリング検出

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019074954A1 (en) * 2017-10-09 2019-04-18 Lifestory Health, Inc. SELECTING BIOMARKERS IN BODY FLUIDS FOR PATIENT STRATIFICATION AND APPLICATION OF A PRECISION MEDICAMENT THROUGH NOVEL DIAGNOSTIC BIOMARKERS
WO2019099948A1 (en) * 2017-11-17 2019-05-23 Bio-Rad Laboratories, Inc. Smart advisor for blood test evaluation
CN110133280B (zh) * 2019-04-29 2022-05-20 融智生物科技(青岛)有限公司 一种β链变异的血红蛋白糖化率的测定方法
CN110658251A (zh) * 2019-10-01 2020-01-07 长沙湘华质谱医学科技有限公司 表征地中海贫血症的特征蛋白组合物或质谱模型的用途
CN111638261B (zh) * 2020-04-17 2023-04-07 融智生物科技(青岛)有限公司 一种计算设备、存储介质和地中海贫血筛查装置及系统
CN114527190A (zh) * 2022-01-14 2022-05-24 融智生物科技(青岛)有限公司 一种糖化血红蛋白检测试剂盒及其检测方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007263896A (ja) * 2006-03-29 2007-10-11 Univ Nagoya 肺癌患者の術後予後予測のための生物マーカー及びその方法
US20080108144A1 (en) * 2004-05-27 2008-05-08 Alam Muhammad A Method for the Rapid Analysis of Polypeptides
US20120107859A1 (en) * 2009-07-07 2012-05-03 Petrotchenko Evgeniy V Methods for early detection of blood disorders
WO2014118634A1 (en) * 2013-01-31 2014-08-07 Eustache Paramithiotis Type 2 diabetes biomarkers and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847209A (en) * 1987-11-09 1989-07-11 Miles Inc. Latex agglutination immunoassay in the presence of hemoglobin
US20040171026A1 (en) * 2001-09-05 2004-09-02 Hochstrasser Denis Francois Diagnostic method for transmissible spongiform encephalopathies
TW200538738A (en) * 2004-02-20 2005-12-01 Univ California Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity
WO2007117794A2 (en) * 2006-03-06 2007-10-18 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Glycated peptides and methods of use
US7951776B2 (en) * 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
US9250248B2 (en) * 2006-11-01 2016-02-02 The Johns Hopkins University Early detection of diabetes
JP2011515680A (ja) * 2008-03-17 2011-05-19 ネルソン,ランドール,ダブリュ. 糖尿病のためのバイオマーカーおよびアッセイ
WO2009144229A1 (en) * 2008-05-27 2009-12-03 F. Hoffmann-La Roche Ag Method for risk reduction in glycemic control
SG195180A1 (en) 2011-05-31 2013-12-30 Singapore Health Serv Pte Ltd Method for detecting disease biomarkers

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080108144A1 (en) * 2004-05-27 2008-05-08 Alam Muhammad A Method for the Rapid Analysis of Polypeptides
JP2007263896A (ja) * 2006-03-29 2007-10-11 Univ Nagoya 肺癌患者の術後予後予測のための生物マーカー及びその方法
US20120107859A1 (en) * 2009-07-07 2012-05-03 Petrotchenko Evgeniy V Methods for early detection of blood disorders
WO2014118634A1 (en) * 2013-01-31 2014-08-07 Eustache Paramithiotis Type 2 diabetes biomarkers and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A.BIROCCIO ET AL.: "A quantitative method for the analysis of glycated and glutathionylated hemoglobin by matrix-assiste", ANALYTICAL BIOCHEMISTRY, vol. 336 (2005), JPN6019018743, 2005, pages 279 - 288, ISSN: 0004040900 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021535380A (ja) * 2018-08-22 2021-12-16 クエスト ダイアグノスティクス インベストメンツ エルエルシー 糖尿病におけるマイクロサンプリング検出

Also Published As

Publication number Publication date
US10161941B2 (en) 2018-12-25
US20170254814A1 (en) 2017-09-07
WO2016030687A1 (en) 2016-03-03
CN107209189A (zh) 2017-09-26
EP3186641B1 (en) 2019-07-17
CN107209189B (zh) 2019-06-14
GB201415369D0 (en) 2014-10-15
EP3186641A1 (en) 2017-07-05

Similar Documents

Publication Publication Date Title
JP2017525972A (ja) グルコシル化ヘモグロビン質量分析法による糖尿病および前糖尿病の迅速なスクリーニングと評価
Stoop et al. Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples
EP1996923B1 (en) Methods for distinguishing isomers using mass spectrometry
Zhao Metabolomics in chronic kidney disease
CN107110873B (zh) 检测血红蛋白中异常的方法
Jensen et al. Quantitation of 25-hydroxyvitamin D in dried blood spots by 2D LC-MS/MS without derivatization and correlation with serum in adult and pediatric studies
CN112903885B (zh) 一种筛查糖尿病的联合型代谢标志物的应用及其试剂盒
KR20170002318A (ko) 대사체 분석을 이용한 당뇨병 조기 진단용 조성물
KR20190045841A (ko) 소변 대사체 분석을 이용한 베체트병의 진단방법
US8691515B2 (en) Methods for early detection of blood disorders
Lapolla et al. Direct evaluation of glycated and glyco‐oxidized globins by matrix‐assisted laser desorption/ionization mass spectrometry
Helmich et al. Rapid phenotype hemoglobin screening by high-resolution mass spectrometry on intact proteins
CN110133280B (zh) 一种β链变异的血红蛋白糖化率的测定方法
KR102100158B1 (ko) N-당사슬 크로마토그램 피크의 상대정량에 의한 질병 스크리닝 방법
JP7748053B2 (ja) 修飾ヌクレオシド分析方法
Pang et al. Technical evaluation of MALDI-TOF mass spectrometry for quantitative proteomic profiling matrix formulation and application
EP2697655A2 (en) Method and apparatus for the analysis of biological samples
Wu et al. A metabolomics approach for predicting the response to intravenous iron therapy in peritoneal dialysis patients with anemia
CA2875331C (en) Methods for diagnosing chronic valvular disease
KR100995496B1 (ko) 가스크로마토그래피-질량분석을 통한 뇨 중의 폴리올 농도 측정방법 및 이를 이용한 유방암 진단용 마커
Bischoff et al. Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples
CN117924412A (zh) 诊断银屑病的分子标志物及其应用
WO2025243982A1 (ja) 尿中修飾ヌクレオシドを用いた補正方法
JP2022068788A (ja) 軽度認知障害における酸化ストレスの評価
Abdel-Hamid et al. Use of Stable Labeled Internal Standards LC-MS/MS Method for the Detection and Confirmation of Inherited Metabolic Diseases in Sick Infants

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170602

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180824

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180824

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20190522

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190528

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20191224