JP2017524725A5 - - Google Patents
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- JP2017524725A5 JP2017524725A5 JP2017514958A JP2017514958A JP2017524725A5 JP 2017524725 A5 JP2017524725 A5 JP 2017524725A5 JP 2017514958 A JP2017514958 A JP 2017514958A JP 2017514958 A JP2017514958 A JP 2017514958A JP 2017524725 A5 JP2017524725 A5 JP 2017524725A5
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- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antibody
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004605P | 2014-05-29 | 2014-05-29 | |
| US62/004,605 | 2014-05-29 | ||
| US201462082681P | 2014-11-21 | 2014-11-21 | |
| US62/082,681 | 2014-11-21 | ||
| PCT/EP2015/061777 WO2015181267A1 (en) | 2014-05-29 | 2015-05-28 | Anti-b7-h3 antibodies and diagnostic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524725A JP2017524725A (ja) | 2017-08-31 |
| JP2017524725A5 true JP2017524725A5 (enExample) | 2018-07-12 |
| JP6636016B2 JP6636016B2 (ja) | 2020-01-29 |
Family
ID=53267378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514958A Active JP6636016B2 (ja) | 2014-05-29 | 2015-05-28 | 抗ｂ７−ｈ３抗体及びその診断用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10501544B2 (enExample) |
| EP (1) | EP3149040A1 (enExample) |
| JP (1) | JP6636016B2 (enExample) |
| AU (1) | AU2015265976B2 (enExample) |
| CA (1) | CA2947660C (enExample) |
| WO (1) | WO2015181267A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015181267A1 (en) * | 2014-05-29 | 2015-12-03 | Spring Bioscience Corporation | Anti-b7-h3 antibodies and diagnostic uses thereof |
| JP2019526529A (ja) * | 2016-06-08 | 2019-09-19 | アッヴィ・インコーポレイテッド | 抗ｂ７−ｈ３抗体及び抗体薬物コンジュゲート |
| BR112019019111A2 (pt) * | 2017-03-31 | 2020-05-05 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo de b7-h3, seu fragmento de ligação ao antígeno e seu uso médico |
| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
| WO2020051275A1 (en) * | 2018-09-05 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Monoclonal antibodies against endotrophin and the use thereof |
| CA3115082A1 (en) * | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | B7h3 single domain antibodies and therapeutic compositions thereof |
| CN113330034A (zh) * | 2018-11-16 | 2021-08-31 | 阿尔伯特爱因斯坦医学院 | 针对B7-H3的IgV结构域的单克隆抗体及其用途 |
| CN109851673B (zh) * | 2019-01-22 | 2023-07-25 | 苏州旭光科星抗体生物科技有限公司 | 一种抗人b7-h3单克隆抗体的制备方法及其免疫组化检测方法及其应用及其试剂盒 |
| EP3962493A2 (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor |
| EP4039702A1 (en) * | 2019-09-16 | 2022-08-10 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Anti-b7-h3 antibody and application thereof |
| CN110642948B (zh) * | 2019-10-09 | 2021-06-29 | 达石药业(广东)有限公司 | B7-h3纳米抗体、其制备方法及用途 |
| EP4076434A1 (en) | 2019-12-17 | 2022-10-26 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| CN113754766A (zh) * | 2020-06-02 | 2021-12-07 | 明慧医药（上海）有限公司 | 抗b7-h3抗体及其制备和应用 |
| US20230355804A1 (en) | 2020-06-29 | 2023-11-09 | Flagship Pioneering Innovations V, Inc. | Viruses engineered to promote thanotransmission and their use in treating cancer |
| KR20230145038A (ko) | 2021-02-09 | 2023-10-17 | 메디링크 테라퓨틱스 (쑤저우) 컴퍼니, 리미티드 | 생물활성 물질 접합체, 이의 제조방법 및 이의 용도 |
| WO2022203414A1 (ko) * | 2021-03-26 | 2022-09-29 | 세라노틱스(주) | B7-h3 항체 또는 이의 항원 결합 단편 및 이의 용도 |
| CA3214085A1 (en) | 2021-03-31 | 2022-10-06 | Darby Rye Schmidt | Thanotransmission polypeptides and their use in treating cancer |
| EP4363059A1 (en) | 2021-06-29 | 2024-05-08 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| US20250230244A1 (en) * | 2021-10-05 | 2025-07-17 | Board Of Regents, The University Of Texas System | Methods and compositions comprising b7-h3 binding polypetides |
| US20230151095A1 (en) | 2021-11-12 | 2023-05-18 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| CN114380910B (zh) * | 2022-01-07 | 2023-04-28 | 苏州旭光科星抗体生物科技有限公司 | 靶向人b7-h3分子的人源化单克隆抗体及其应用 |
| EP4480499A1 (en) | 2022-02-16 | 2024-12-25 | Medilink Therapeutics (Suzhou) Co., Ltd. | Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof |
| WO2023177232A1 (ko) * | 2022-03-18 | 2023-09-21 | 세종대학교산학협력단 | 항 b7-h3 단일클론항체 및 이의 용도 |
| JP2025516873A (ja) | 2022-05-18 | 2025-05-30 | ▲蘇▼州宜▲聯▼生物医▲薬▼有限公司 | タンパク質分解剤クラスの生物学的活性化合物を含む抗体薬物複合体及びその調製方法並びに使用 |
| CN114773477B (zh) * | 2022-06-23 | 2022-09-09 | 上海优替济生生物医药有限公司 | 抗b7-h3抗体及其用途 |
| EP4598946A1 (en) | 2022-10-05 | 2025-08-13 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024102636A1 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and mica/b |
| WO2024102693A2 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Il-18-fc fusion proteins |
| CN120787161A (zh) * | 2023-01-30 | 2025-10-14 | 德克萨斯大学体系董事会 | 对B7-H3的4Ig同种型具有选择性的抗体及其使用方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060154313A1 (en) * | 2000-04-13 | 2006-07-13 | Immunex Corporation | Human B7 polypeptide B7-H3A |
| CA2463464A1 (en) * | 2003-04-28 | 2004-10-28 | Auckland Uniservices Limited | Methods of treatment and compositions therefor |
| ES2259270B1 (es) * | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| EP2399130A4 (en) * | 2009-02-20 | 2012-06-06 | Wayne John Cancer Inst | ASSAY OF B7-H3 ANTIBODY-COUPLED BEADS FOR THE ISOLATION AND DETECTION OF CIRCULATING TUMOR CELLS IN THE BODILY FLUIDS OF MELANOMA AND BREAST CANCER PATIENTS |
| CN101959216B (zh) | 2009-07-20 | 2014-06-18 | 电信科学技术研究院 | 一种分载波配置增强cell_fach的方法、系统和设备 |
| PH12012501751A1 (en) * | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| DK2542256T3 (da) * | 2010-03-04 | 2019-08-26 | Macrogenics Inc | Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf |
| KR20130043104A (ko) * | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| US20140148350A1 (en) * | 2010-08-18 | 2014-05-29 | David Spetzler | Circulating biomarkers for disease |
| ES2667568T3 (es) * | 2011-04-25 | 2018-05-11 | Daiichi Sankyo Company, Limited | Anticuerpo anti-B7-H3 |
| WO2015181267A1 (en) * | 2014-05-29 | 2015-12-03 | Spring Bioscience Corporation | Anti-b7-h3 antibodies and diagnostic uses thereof |
-
2015
- 2015-05-28 WO PCT/EP2015/061777 patent/WO2015181267A1/en not_active Ceased
- 2015-05-28 EP EP15724692.7A patent/EP3149040A1/en not_active Withdrawn
- 2015-05-28 CA CA2947660A patent/CA2947660C/en active Active
- 2015-05-28 JP JP2017514958A patent/JP6636016B2/ja active Active
- 2015-05-28 AU AU2015265976A patent/AU2015265976B2/en active Active
-
2016
- 2016-11-29 US US15/363,992 patent/US10501544B2/en active Active
-
2019
- 2019-10-28 US US16/665,359 patent/US11525003B2/en active Active
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