JP2017524725A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017524725A5 JP2017524725A5 JP2017514958A JP2017514958A JP2017524725A5 JP 2017524725 A5 JP2017524725 A5 JP 2017524725A5 JP 2017514958 A JP2017514958 A JP 2017514958A JP 2017514958 A JP2017514958 A JP 2017514958A JP 2017524725 A5 JP2017524725 A5 JP 2017524725A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antibody
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462004605P | 2014-05-29 | 2014-05-29 | |
| US62/004,605 | 2014-05-29 | ||
| US201462082681P | 2014-11-21 | 2014-11-21 | |
| US62/082,681 | 2014-11-21 | ||
| PCT/EP2015/061777 WO2015181267A1 (en) | 2014-05-29 | 2015-05-28 | Anti-b7-h3 antibodies and diagnostic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017524725A JP2017524725A (ja) | 2017-08-31 |
| JP2017524725A5 true JP2017524725A5 (enExample) | 2018-07-12 |
| JP6636016B2 JP6636016B2 (ja) | 2020-01-29 |
Family
ID=53267378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514958A Active JP6636016B2 (ja) | 2014-05-29 | 2015-05-28 | 抗ｂ７−ｈ３抗体及びその診断用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10501544B2 (enExample) |
| EP (1) | EP3149040A1 (enExample) |
| JP (1) | JP6636016B2 (enExample) |
| AU (1) | AU2015265976B2 (enExample) |
| CA (1) | CA2947660C (enExample) |
| WO (1) | WO2015181267A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3149040A1 (en) * | 2014-05-29 | 2017-04-05 | Spring Bioscience Corporation | Anti-b7-h3 antibodies and diagnostic uses thereof |
| JP2019526529A (ja) * | 2016-06-08 | 2019-09-19 | アッヴィ・インコーポレイテッド | 抗ｂ７−ｈ３抗体及び抗体薬物コンジュゲート |
| CA3056474A1 (en) * | 2017-03-31 | 2018-10-04 | Jiangsu Hengrui Medicine Co., Ltd. | B7-h3 antibody, antigen-binding fragment thereof and medical use thereof |
| WO2019241730A2 (en) | 2018-06-15 | 2019-12-19 | Flagship Pioneering Innovations V, Inc. | Increasing immune activity through modulation of postcellular signaling factors |
| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
| US12331110B2 (en) | 2018-09-05 | 2025-06-17 | The Board Of Regents Of The University Of Texas System | Monoclonal antibodies against endotrophin and the use thereof |
| CN113166261A (zh) * | 2018-10-11 | 2021-07-23 | 印希比股份有限公司 | B7h3单域抗体及其治疗性组合物 |
| CN113330034A (zh) | 2018-11-16 | 2021-08-31 | 阿尔伯特爱因斯坦医学院 | 针对B7-H3的IgV结构域的单克隆抗体及其用途 |
| CN109851673B (zh) * | 2019-01-22 | 2023-07-25 | 苏州旭光科星抗体生物科技有限公司 | 一种抗人b7-h3单克隆抗体的制备方法及其免疫组化检测方法及其应用及其试剂盒 |
| MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
| EP4039702A1 (en) * | 2019-09-16 | 2022-08-10 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Anti-b7-h3 antibody and application thereof |
| CN110642948B (zh) | 2019-10-09 | 2021-06-29 | 达石药业(广东)有限公司 | B7-h3纳米抗体、其制备方法及用途 |
| KR20220115572A (ko) | 2019-11-18 | 2022-08-17 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 항-b7-h3 단클론성 항체 및 이의 사용 방법 |
| JP2023509359A (ja) | 2019-12-17 | 2023-03-08 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | 鉄依存性細胞分解の誘導物質との併用抗癌療法 |
| CN113754766A (zh) * | 2020-06-02 | 2021-12-07 | 明慧医药（上海）有限公司 | 抗b7-h3抗体及其制备和应用 |
| CN116096906A (zh) | 2020-06-29 | 2023-05-09 | 旗舰创业创新五公司 | 工程化以促进萨诺传递的病毒及其在治疗癌症中的用途 |
| CN120093941A (zh) | 2021-02-09 | 2025-06-06 | 苏州宜联生物医药有限公司 | 生物活性物偶联物及其制备方法和用途 |
| WO2022203414A1 (ko) * | 2021-03-26 | 2022-09-29 | 세라노틱스(주) | B7-h3 항체 또는 이의 항원 결합 단편 및 이의 용도 |
| EP4313109A1 (en) | 2021-03-31 | 2024-02-07 | Flagship Pioneering Innovations V, Inc. | Thanotransmission polypeptides and their use in treating cancer |
| US20240316104A1 (en) | 2021-06-29 | 2024-09-26 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| CN118715242A (zh) * | 2021-10-05 | 2024-09-27 | 得克萨斯州大学系统董事会 | 包含b7-h3结合多肽的组合物和方法 |
| US20230151095A1 (en) | 2021-11-12 | 2023-05-18 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| CN114380910B (zh) * | 2022-01-07 | 2023-04-28 | 苏州旭光科星抗体生物科技有限公司 | 靶向人b7-h3分子的人源化单克隆抗体及其应用 |
| EP4480499A1 (en) | 2022-02-16 | 2024-12-25 | Medilink Therapeutics (Suzhou) Co., Ltd. | Conjugate of antibody-eribulin or derivative thereof, intermediate thereof, preparation method therefor, pharmaceutical composition thereof and use thereof |
| WO2023177232A1 (ko) * | 2022-03-18 | 2023-09-21 | 세종대학교산학협력단 | 항 b7-h3 단일클론항체 및 이의 용도 |
| EP4527415A1 (en) | 2022-05-18 | 2025-03-26 | Medilink Therapeutics (Suzhou) Co., Ltd. | Antibody-drug conjugate containing protein degradation agent bioactive compound, method for preparing same, and use thereof |
| CN114773477B (zh) * | 2022-06-23 | 2022-09-09 | 上海优替济生生物医药有限公司 | 抗b7-h3抗体及其用途 |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024102636A1 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and mica/b |
| WO2024102693A2 (en) | 2022-11-07 | 2024-05-16 | Xencor, Inc. | Il-18-fc fusion proteins |
| WO2024163499A1 (en) * | 2023-01-30 | 2024-08-08 | Board Of Regents, The University Of Texas System | Antibodies with selectivity for the 4ig isoform of b7-h3 and methods of use thereof |
| CN119454937A (zh) | 2023-11-13 | 2025-02-18 | 苏州宜联生物医药有限公司 | 抗b7h3抗体-药物偶联物治疗癌症的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060154313A1 (en) * | 2000-04-13 | 2006-07-13 | Immunex Corporation | Human B7 polypeptide B7-H3A |
| US20050070474A1 (en) * | 2003-04-28 | 2005-03-31 | Krissansen Geoffrey Wayne | Methods of treatment and compositions therefor |
| ES2259270B1 (es) * | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| EP2399130A4 (en) * | 2009-02-20 | 2012-06-06 | Wayne John Cancer Inst | ASSAY OF B7-H3 ANTIBODY-COUPLED BEADS FOR THE ISOLATION AND DETECTION OF CIRCULATING TUMOR CELLS IN THE BODILY FLUIDS OF MELANOMA AND BREAST CANCER PATIENTS |
| CN101959216B (zh) | 2009-07-20 | 2014-06-18 | 电信科学技术研究院 | 一种分载波配置增强cell_fach的方法、系统和设备 |
| PH12012501751A1 (en) * | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| DK2542256T3 (da) * | 2010-03-04 | 2019-08-26 | Macrogenics Inc | Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf |
| KR20130043104A (ko) * | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| WO2012024543A1 (en) * | 2010-08-18 | 2012-02-23 | Caris Life Sciences Luxembourg Holdings | Circulating biomarkers for disease |
| EP2703486B1 (en) * | 2011-04-25 | 2018-03-07 | Daiichi Sankyo Company, Limited | Anti-b7-h3 antibody |
| EP3149040A1 (en) * | 2014-05-29 | 2017-04-05 | Spring Bioscience Corporation | Anti-b7-h3 antibodies and diagnostic uses thereof |
-
2015
- 2015-05-28 EP EP15724692.7A patent/EP3149040A1/en not_active Withdrawn
- 2015-05-28 AU AU2015265976A patent/AU2015265976B2/en active Active
- 2015-05-28 JP JP2017514958A patent/JP6636016B2/ja active Active
- 2015-05-28 WO PCT/EP2015/061777 patent/WO2015181267A1/en not_active Ceased
- 2015-05-28 CA CA2947660A patent/CA2947660C/en active Active
-
2016
- 2016-11-29 US US15/363,992 patent/US10501544B2/en active Active
-
2019
- 2019-10-28 US US16/665,359 patent/US11525003B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017518366A5 (enExample) | ||
| RU2010117018A (ru) | Антитела к gdf8 и их применения | |
| RU2015103228A (ru) | Антитела против тау | |
| RU2015155552A (ru) | Путеспецифические способы прогнозирования диагноза синдрома раздраженного кишечника | |
| AU2015265976A1 (en) | Anti-B7-H3 antibodies and diagnostic uses thereof | |
| CN113891746A (zh) | 焦谷氨酸淀粉样蛋白-β的抗体及其用途 | |
| JP2016500659A5 (enExample) | ||
| JP7557023B2 (ja) | 多発性骨髄腫におけるｍタンパク質反応の臨床評価 | |
| JP2016516008A5 (enExample) | ||
| JP2017524362A5 (enExample) | ||
| EP2870178A1 (en) | Anti-c-met antibodies | |
| JP2018527895A5 (enExample) | ||
| JP2018515071A5 (enExample) | ||
| CN121219584A (zh) | 针对nr1的自身抗体的检测 | |
| Lee et al. | Identification of secreted and membrane-bound bat immunoglobulin using a Microchiropteran-specific mouse monoclonal antibody | |
| JP2018520366A5 (enExample) | ||
| CN110997727A (zh) | 用于确定微型猪样品中抗药物抗体的方法 | |
| US12449421B1 (en) | Anti-CD79B protein monoclonal antibody, products containing the same, and uses thereof | |
| US20230242636A1 (en) | Monoclonal antibodies targeted to human taxilin alpha and methods for use of same | |
| KR102688094B1 (ko) | Cobll1 단백질 특이 항체 또는 이의 항원 결합 단편, 및 이의 용도 | |
| CA3016098C (en) | Clinical assessment of m-protein response in multiple myeloma | |
| WO2020010304A2 (en) | BCl-2 Antibodies and Immunoassay for Diagnosis of Cancer | |
| WO2014073653A1 (ja) | 腎炎の病変部位の検査方法およびそのための試薬 |