JP2017524689A5 - - Google Patents

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Publication number
JP2017524689A5
JP2017524689A5 JP2017500864A JP2017500864A JP2017524689A5 JP 2017524689 A5 JP2017524689 A5 JP 2017524689A5 JP 2017500864 A JP2017500864 A JP 2017500864A JP 2017500864 A JP2017500864 A JP 2017500864A JP 2017524689 A5 JP2017524689 A5 JP 2017524689A5
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JP
Japan
Prior art keywords
antibody
snap25
bont
seq
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2017500864A
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English (en)
Japanese (ja)
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JP2017524689A (ja
JP6630717B2 (ja
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Priority claimed from PCT/US2015/039372 external-priority patent/WO2016007508A1/en
Publication of JP2017524689A publication Critical patent/JP2017524689A/ja
Publication of JP2017524689A5 publication Critical patent/JP2017524689A5/ja
Application granted granted Critical
Publication of JP6630717B2 publication Critical patent/JP6630717B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017500864A 2014-07-07 2015-07-07 組織試料における切断ｓｎａｐ２５の検出方法 Expired - Fee Related JP6630717B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462021379P 2014-07-07 2014-07-07
US62/021,379 2014-07-07
US201562158900P 2015-05-08 2015-05-08
US62/158,900 2015-05-08
US201562163829P 2015-05-19 2015-05-19
US62/163,829 2015-05-19
PCT/US2015/039372 WO2016007508A1 (en) 2014-07-07 2015-07-07 Method of detecting cleaved snap25 in tissue samples

Publications (3)

Publication Number Publication Date
JP2017524689A JP2017524689A (ja) 2017-08-31
JP2017524689A5 true JP2017524689A5 (https=) 2018-08-16
JP6630717B2 JP6630717B2 (ja) 2020-01-15

Family

ID=55016834

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017500864A Expired - Fee Related JP6630717B2 (ja) 2014-07-07 2015-07-07 組織試料における切断ｓｎａｐ２５の検出方法

Country Status (6)

Country Link
US (2) US10527620B2 (https=)
EP (2) EP3567055A1 (https=)
JP (1) JP6630717B2 (https=)
KR (1) KR20170026624A (https=)
CN (1) CN107001451A (https=)
CA (1) CA2954504A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2271670E (pt) * 2008-03-14 2014-11-28 Allergan Inc Ensaio imunobaseado da atividade do serotipo a da toxina botulínica
EP3825689A3 (en) 2018-11-29 2021-09-15 Hugel Inc. A cell-based method for determining an activity of botulinum toxin
KR101983216B1 (ko) * 2018-11-29 2019-05-29 주식회사 에이비바이오 보툴리눔 독소 활성을 결정하기 위한 항체, 및 이를 이용한 활성 측정방법
WO2022043924A1 (en) * 2020-08-28 2022-03-03 Galderma Holding SA Novel x-aptamers for the use in detection of snap25
CN119044508B (zh) * 2024-10-31 2025-01-28 兰州生物技术开发有限公司 检测肉毒毒素活性或突触体相关蛋白的试剂盒及检测方法
CN119044510B (zh) * 2024-10-31 2025-01-28 兰州生物技术开发有限公司 一种测定肉毒毒素活性或snap25的试剂盒、抗体及方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5962637A (en) 1994-06-03 1999-10-05 Microbiological Research Authority Toxin assay
GB9411138D0 (en) 1994-06-03 1994-07-27 Microbiological Res Authority Toxin assay
GB9508204D0 (en) 1995-04-21 1995-06-07 Speywood Lab Ltd A novel agent able to modify peripheral afferent function
US20040219619A1 (en) 2000-07-21 2004-11-04 Ester Fernandez-Salas Methods of identifying compounds that alter toxin persistence and/or protease activity
WO2003011902A1 (en) * 2001-07-27 2003-02-13 Kenton S.R.L. Identification of specific tumour antigens by selection of cdna libraries with sera
US7208285B2 (en) 2001-08-28 2007-04-24 Allergan, Inc. Fret protease assays for botulinum serotype A/E toxins
US7332567B2 (en) 2001-08-28 2008-02-19 Allergan, Inc. Fret protease assays for clostridial toxins
US7183066B2 (en) 2002-09-27 2007-02-27 Allergan, Inc. Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins
ES2374822T3 (es) 2004-02-24 2012-02-22 Allergan, Inc. Ensayo de selección de toxinas botul�?nicas.
US7399607B2 (en) 2004-09-22 2008-07-15 Allergan, Inc. Fluorescence polarization assays for determining clostridial toxin activity
US20070258992A1 (en) 2004-10-06 2007-11-08 Atassi M Zouhair Determining and Reducing Immunoresistance to Botulinum Toxin Therapy Using Botulinum Toxin a Peptides
EP2293064B1 (en) 2005-04-05 2012-04-04 Allergan, Inc. Lipophilic dye-based FRET assays for clostridial toxin activity
US20100227868A1 (en) 2007-09-20 2010-09-09 Johnson Brent A Treatment methods with brimonidine
KR101604515B1 (ko) * 2008-03-14 2016-03-17 알러간, 인코포레이티드 면역-기반 보툴리눔 독소 세로타입 ａ 활성 검정
PT2271670E (pt) 2008-03-14 2014-11-28 Allergan Inc Ensaio imunobaseado da atividade do serotipo a da toxina botulínica
BRPI1008940A2 (pt) 2009-03-13 2020-10-27 Allergan, Inc. linhagem de célula clonal estabelecida suscetível à intoxicação por bont/a
KR101923847B1 (ko) * 2009-03-13 2018-11-29 알러간, 인코포레이티드 면역 기반 재표적화된 엔도펩티다제 활성 검정
SG10201405069QA (en) * 2009-08-25 2014-10-30 Berg Llc Methods for treatment of a sarcoma using an epimetabolic shifter (coenzyme q10)
CN105683212B (zh) * 2013-08-21 2020-03-17 香港理工大学 高催化活性的基因改造梭菌属神经毒素

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