JP2017519778A5 - - Google Patents
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- Publication number
- JP2017519778A5 JP2017519778A5 JP2016575106A JP2016575106A JP2017519778A5 JP 2017519778 A5 JP2017519778 A5 JP 2017519778A5 JP 2016575106 A JP2016575106 A JP 2016575106A JP 2016575106 A JP2016575106 A JP 2016575106A JP 2017519778 A5 JP2017519778 A5 JP 2017519778A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- migraine
- compound
- composition according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 26
- 208000019695 Migraine disease Diseases 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 17
- 206010027599 migraine Diseases 0.000 claims 17
- 150000003839 salts Chemical class 0.000 claims 15
- 230000005764 inhibitory process Effects 0.000 claims 4
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 4
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims 4
- 239000001961 anticonvulsive agent Substances 0.000 claims 3
- 208000006561 Cluster Headache Diseases 0.000 claims 2
- 206010052784 Retinal migraine Diseases 0.000 claims 2
- 208000030886 Traumatic Brain injury Diseases 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims 2
- 239000000935 antidepressant agent Substances 0.000 claims 2
- 229940005513 antidepressants Drugs 0.000 claims 2
- 229960003965 antiepileptics Drugs 0.000 claims 2
- 230000001054 cortical effect Effects 0.000 claims 2
- 230000002354 daily effect Effects 0.000 claims 2
- 230000003203 everyday effect Effects 0.000 claims 2
- 230000007774 longterm Effects 0.000 claims 2
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 229940076279 serotonin Drugs 0.000 claims 2
- 230000001052 transient effect Effects 0.000 claims 2
- 230000009529 traumatic brain injury Effects 0.000 claims 2
- 230000003442 weekly effect Effects 0.000 claims 2
- KRQUFUKTQHISJB-YYADALCUSA-N 2-[(E)-N-[2-(4-chlorophenoxy)propoxy]-C-propylcarbonimidoyl]-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-one Chemical compound CCC\C(=N/OCC(C)OC1=CC=C(Cl)C=C1)C1=C(O)CC(CC1=O)C1CCCSC1 KRQUFUKTQHISJB-YYADALCUSA-N 0.000 claims 1
- 206010049714 Abdominal migraine Diseases 0.000 claims 1
- 208000004454 Hyperalgesia Diseases 0.000 claims 1
- 208000000060 Migraine with aura Diseases 0.000 claims 1
- 206010053552 allodynia Diseases 0.000 claims 1
- 230000001430 anti-depressive effect Effects 0.000 claims 1
- -1 anti-seizure drugs Substances 0.000 claims 1
- 229940125681 anticonvulsant agent Drugs 0.000 claims 1
- 208000018912 cluster headache syndrome Diseases 0.000 claims 1
- 239000002934 diuretic Substances 0.000 claims 1
- 229940030606 diuretics Drugs 0.000 claims 1
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 claims 1
- 229940005483 opioid analgesics Drugs 0.000 claims 1
- 230000000737 periodic effect Effects 0.000 claims 1
- 239000002243 precursor Substances 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462015727P | 2014-06-23 | 2014-06-23 | |
| US62/015,727 | 2014-06-23 | ||
| US201562109386P | 2015-01-29 | 2015-01-29 | |
| US62/109,386 | 2015-01-29 | ||
| PCT/US2015/037177 WO2015200322A1 (en) | 2014-06-23 | 2015-06-23 | Methods of treating or ameliorating migraine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020068289A Division JP2020114863A (ja) | 2014-06-23 | 2020-04-06 | 片頭痛の治療または改善方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017519778A JP2017519778A (ja) | 2017-07-20 |
| JP2017519778A5 true JP2017519778A5 (https=) | 2018-08-02 |
| JP6688748B2 JP6688748B2 (ja) | 2020-04-28 |
Family
ID=54938737
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016575106A Active JP6688748B2 (ja) | 2014-06-23 | 2015-06-23 | 片頭痛の治療または改善方法 |
| JP2020068289A Pending JP2020114863A (ja) | 2014-06-23 | 2020-04-06 | 片頭痛の治療または改善方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020068289A Pending JP2020114863A (ja) | 2014-06-23 | 2020-04-06 | 片頭痛の治療または改善方法 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3157943A4 (https=) |
| JP (2) | JP6688748B2 (https=) |
| KR (1) | KR20170018072A (https=) |
| CN (1) | CN106661085A (https=) |
| AU (1) | AU2015280108B2 (https=) |
| BR (1) | BR112016030375A8 (https=) |
| CA (1) | CA2953170A1 (https=) |
| MX (1) | MX2016017388A (https=) |
| RU (1) | RU2721401C2 (https=) |
| WO (1) | WO2015200322A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7476229B2 (ja) * | 2019-04-15 | 2024-04-30 | フェリン・ファーマシューティカルズ・インコーポレイテッド | 片頭痛の治療 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995006468A1 (en) * | 1993-09-01 | 1995-03-09 | Smithkline Beecham Corporation | Method for treating migraine headaches |
| DE60131032T2 (de) * | 2000-08-25 | 2008-08-14 | Research Corp. Technologies, Inc., Tucson | Verwendung von antikonvulsiven Aminosäure zur Behandlung von Migräne |
| EP1337559A2 (en) * | 2000-11-17 | 2003-08-27 | Bayer Ag | Regulation of human nmda receptor |
| ES2381091T3 (es) * | 2003-03-06 | 2012-05-23 | Botulinum Toxin Research Associates, Inc. | Tratamiento del dolor facial crónico y cefalea relacionados con la sinusitis con toxina botulínica |
| NZ590793A (en) * | 2008-07-23 | 2012-07-27 | Kyowa Hakko Kirin Co Ltd | Therapeutic agent for migraine |
| WO2011003064A2 (en) * | 2009-07-02 | 2011-01-06 | Naurex, Inc. | Methods of treating neuropathic pain |
| US8951968B2 (en) * | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
| PL2485751T3 (pl) * | 2009-10-05 | 2014-10-31 | Univ Northwestern | GLYX-13 do stosowania w sposobie leczenia depresji opornej na leczenie |
| CN105037492A (zh) * | 2010-02-11 | 2015-11-11 | 西北大学 | 二级结构稳定化的nmda受体调节剂及其用途 |
| US20140107037A1 (en) * | 2011-04-27 | 2014-04-17 | Northwestern University | Methods of treating alzheimer's disease, huntington's disease, autism, or other disorders |
| US20150253305A1 (en) * | 2012-10-12 | 2015-09-10 | Northwestern University | Methods of identifying compounds for treating depression and other related diseases |
-
2015
- 2015-06-23 CN CN201580033913.6A patent/CN106661085A/zh active Pending
- 2015-06-23 WO PCT/US2015/037177 patent/WO2015200322A1/en not_active Ceased
- 2015-06-23 CA CA2953170A patent/CA2953170A1/en not_active Abandoned
- 2015-06-23 JP JP2016575106A patent/JP6688748B2/ja active Active
- 2015-06-23 AU AU2015280108A patent/AU2015280108B2/en not_active Ceased
- 2015-06-23 BR BR112016030375A patent/BR112016030375A8/pt not_active IP Right Cessation
- 2015-06-23 EP EP15811633.5A patent/EP3157943A4/en not_active Withdrawn
- 2015-06-23 MX MX2016017388A patent/MX2016017388A/es unknown
- 2015-06-23 KR KR1020177001848A patent/KR20170018072A/ko not_active Ceased
- 2015-06-23 RU RU2017101410A patent/RU2721401C2/ru active
-
2020
- 2020-04-06 JP JP2020068289A patent/JP2020114863A/ja active Pending
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