JP2017514868A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017514868A5 JP2017514868A5 JP2016566811A JP2016566811A JP2017514868A5 JP 2017514868 A5 JP2017514868 A5 JP 2017514868A5 JP 2016566811 A JP2016566811 A JP 2016566811A JP 2016566811 A JP2016566811 A JP 2016566811A JP 2017514868 A5 JP2017514868 A5 JP 2017514868A5
- Authority
- JP
- Japan
- Prior art keywords
- concentration
- composition
- polysorbate
- present
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14167405 | 2014-05-07 | ||
| EP14167405.1 | 2014-05-07 | ||
| US201461994319P | 2014-05-16 | 2014-05-16 | |
| US61/994,319 | 2014-05-16 | ||
| US201462043636P | 2014-08-29 | 2014-08-29 | |
| US62/043,636 | 2014-08-29 | ||
| PCT/EP2015/059709 WO2015169742A1 (en) | 2014-05-07 | 2015-05-04 | Liquid formulation comprising gm-csf neutralizing compound |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017514868A JP2017514868A (ja) | 2017-06-08 |
| JP2017514868A5 true JP2017514868A5 (enExample) | 2018-06-14 |
| JP6769879B2 JP6769879B2 (ja) | 2020-10-14 |
Family
ID=50721582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016566811A Expired - Fee Related JP6769879B2 (ja) | 2014-05-07 | 2015-05-04 | Ｇｍ−ｃｓｆ中和化合物を含む液体製剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11173208B2 (enExample) |
| EP (1) | EP3139960B1 (enExample) |
| JP (1) | JP6769879B2 (enExample) |
| KR (1) | KR102385802B1 (enExample) |
| CN (1) | CN106659785B (enExample) |
| AR (1) | AR100268A1 (enExample) |
| AU (1) | AU2015257798C1 (enExample) |
| BR (1) | BR112016025126B1 (enExample) |
| EA (1) | EA201691883A1 (enExample) |
| ES (1) | ES2974895T3 (enExample) |
| MX (1) | MX387451B (enExample) |
| PH (1) | PH12016502100A1 (enExample) |
| TW (1) | TWI682788B (enExample) |
| WO (1) | WO2015169742A1 (enExample) |
| ZA (1) | ZA201607097B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3615066T3 (pl) | 2017-04-28 | 2024-04-29 | Amgen Inc. | Formulacje ludzkich przeciwciał anty-RANKL i sposoby ich zastosowania |
| CN107167613B (zh) * | 2017-06-22 | 2018-10-02 | 深圳清华大学研究院 | 用于等离子体金芯片的蛋白点样缓冲液 |
| WO2020072306A1 (en) * | 2018-10-01 | 2020-04-09 | Amgen Inc. | Methods for reducing aggregation of bispecific antibodies |
| US11267858B2 (en) | 2019-05-31 | 2022-03-08 | Spectrum Pharmaceuticals, Inc. | Methods of treatment using G-CSF protein complex |
| US11684655B2 (en) | 2019-05-31 | 2023-06-27 | Spectrum Pharmaceuticals, Inc. | Methods of treating neutorpenia using G-CSF protein complex |
| AU2020370372A1 (en) * | 2019-10-25 | 2022-05-12 | Amgen Inc. | Compositions and methods for minimizing protein loss at low protein concentrations |
| CA3183934A1 (en) * | 2020-05-29 | 2021-12-02 | Amgen Inc. | Antibody formulations and uses thereof |
| JP2023551549A (ja) * | 2020-12-04 | 2023-12-08 | シーエスエル イノベーション プロプライアタリー リミティド | 炎症性皮膚状態を治療する方法 |
| JP2024501659A (ja) * | 2020-12-21 | 2024-01-15 | シーエスエル イノベーション プロプライアタリー リミティド | 急性呼吸窮迫症候群を治療又は防止するための方法 |
| CN117062609A (zh) * | 2020-12-21 | 2023-11-14 | Csl创新私人有限公司 | 用于治疗或预防急性呼吸窘迫综合征的方法 |
| KR102375269B1 (ko) * | 2021-01-27 | 2022-03-17 | 한미약품 주식회사 | 단백질 액상 제제 및 이의 제조방법 |
| EP4337257A1 (en) * | 2021-05-12 | 2024-03-20 | AnaptysBio, Inc. | Antibody composition |
| CN119095584A (zh) * | 2022-12-01 | 2024-12-06 | 天境生物科技(杭州)有限公司 | 抗gm-csf抗体的液体药物配制品及其用途 |
| WO2025217676A1 (en) * | 2024-04-15 | 2025-10-23 | CSL Innovation Pty Ltd | Protein formulations and uses thereof |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2916711A1 (de) | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
| US4783441A (en) | 1979-04-30 | 1988-11-08 | Hoechst Aktiengesellschaft | Aqueous protein solutions stable to denaturation |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0158487B1 (en) | 1984-04-09 | 1991-08-28 | Takeda Chemical Industries, Ltd. | Stable composition of interleukin-2 |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| GB8903593D0 (en) | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| WO1994009149A1 (en) | 1990-08-10 | 1994-04-28 | Amrad Corporation Limited | Monoclonal antibody |
| US5580856A (en) | 1994-07-15 | 1996-12-03 | Prestrelski; Steven J. | Formulation of a reconstituted protein, and method and kit for the production thereof |
| US6685940B2 (en) | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| CA2226575C (en) * | 1995-07-27 | 2011-10-18 | Genentech, Inc. | Stabile isotonic lyophilized protein formulation |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| CA2326389C (en) | 1998-04-21 | 2007-01-23 | Micromet Gesellschaft Fur Biomedizinische Forschung Mbh | Novel cd19xcd3 specific polypeptides and uses thereof |
| US20030138417A1 (en) * | 2001-11-08 | 2003-07-24 | Kaisheva Elizabet A. | Stable liquid pharmaceutical formulation of IgG antibodies |
| CA2476934C (en) | 2002-02-27 | 2009-06-16 | Immunex Corporation | Stabilized tnfr-fc composition comprising arginine |
| US7511476B2 (en) * | 2005-01-04 | 2009-03-31 | Digisensors, Inc. | Electromagnetic sensor systems and methods of use thereof |
| MX2007012569A (es) * | 2005-04-18 | 2007-12-06 | Micromet Ag | Neutralizadores de anticuerpos del factor estimulante de la colonia de macrofagos-granulocitos humanos. |
| ES2918209T3 (es) | 2005-05-18 | 2022-07-14 | Morphosys Ag | Anticuerpos anti-GM-CSF y usos a partir de los mismos |
| JP4736037B2 (ja) | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| KR101395515B1 (ko) | 2006-02-08 | 2014-05-14 | 모르포테크, 인크. | 항원성 ｇｍ-ｃｓｆ 펩티드 및 ｇｍ-ｃｓｆ에 대한 항체 |
| KR101481844B1 (ko) | 2006-03-27 | 2015-01-13 | 메디뮨 리미티드 | Ｇｍ-ｃｓｆ 수용체에 대한 결합 성분 |
| EP1970384A1 (en) * | 2007-03-14 | 2008-09-17 | Ganymed Pharmaceuticals AG | Monoclonal antibodies for treatment of cancer |
| AU2008269086B2 (en) | 2007-06-25 | 2014-06-12 | Amgen Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| TW200918553A (en) * | 2007-09-18 | 2009-05-01 | Amgen Inc | Human GM-CSF antigen binding proteins |
| US8679502B2 (en) | 2007-11-13 | 2014-03-25 | Evec Inc. | Monoclonal antibodies that bind to HGM-CSF and medical compositions comprising same |
| KR101824512B1 (ko) | 2008-04-28 | 2018-02-02 | 휴머니건, 아이엔씨. | 과립구-대식세포 콜로니 자극 인자에 대한 항체 |
| RU2481824C2 (ru) * | 2008-10-29 | 2013-05-20 | Аблинкс Н.В | Препараты однодоменных антигенсвязывающих молекул |
| US20110158987A1 (en) | 2009-12-29 | 2011-06-30 | F. Hoffmann-Laroche Ag | Novel antibody formulation |
| CN104995210A (zh) * | 2012-09-20 | 2015-10-21 | 莫弗系统股份公司 | 类风湿关节炎的治疗 |
| AR093297A1 (es) * | 2012-10-31 | 2015-05-27 | Amgen Res Munich Gmbh | Formulacion liquida que comprende un compuesto neutralizante de gm-csf |
-
2015
- 2015-05-04 US US15/307,214 patent/US11173208B2/en active Active
- 2015-05-04 BR BR112016025126-1A patent/BR112016025126B1/pt active IP Right Grant
- 2015-05-04 WO PCT/EP2015/059709 patent/WO2015169742A1/en not_active Ceased
- 2015-05-04 JP JP2016566811A patent/JP6769879B2/ja not_active Expired - Fee Related
- 2015-05-04 MX MX2016014411A patent/MX387451B/es unknown
- 2015-05-04 KR KR1020167031014A patent/KR102385802B1/ko active Active
- 2015-05-04 EP EP15720968.5A patent/EP3139960B1/en active Active
- 2015-05-04 CN CN201580037108.0A patent/CN106659785B/zh active Active
- 2015-05-04 AR ARP150101336A patent/AR100268A1/es not_active Application Discontinuation
- 2015-05-04 AU AU2015257798A patent/AU2015257798C1/en active Active
- 2015-05-04 EA EA201691883A patent/EA201691883A1/ru unknown
- 2015-05-04 ES ES15720968T patent/ES2974895T3/es active Active
- 2015-05-07 TW TW104114614A patent/TWI682788B/zh active
-
2016
- 2016-10-14 ZA ZA2016/07097A patent/ZA201607097B/en unknown
- 2016-10-20 PH PH12016502100A patent/PH12016502100A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20120903T1 (hr) | Tekuä†a formulacija koja sadrži visoku koncentraciju protutijela | |
| PH12017500844A1 (en) | Stable protein solution formulation containing high concentration of an anti-vegf antibody | |
| JP2014129360A5 (enExample) | ||
| JP2015231997A5 (enExample) | ||
| JOP20210152A1 (ar) | صياغة محلول بروتيني محتوية على تركيز عالٍ من جسم مضاد لـ vegf | |
| HRP20241131T1 (hr) | Visokokoncentrirane formulacije inhibitornih antitijela masp-2 niske viskoznosti, pribori i metode | |
| JP2016534052A5 (enExample) | ||
| TW201422235A (zh) | 抗－泌乳素受器抗體配方 | |
| JP2023126930A (ja) | 治療用タンパク質の凍結乾燥医薬配合物のためのプロセス | |
| EA201892446A1 (ru) | Фармацевтическая композиция | |
| EP4527403A3 (en) | Dual function proteins and pharmaceutical composition comprising same | |
| JP2013543505A5 (enExample) | ||
| AR079836A1 (es) | Formulaciones estabilizadas que contienen anticuerpos anti-receptor de interleuquina-6 (il-6r) | |
| JP2017531682A5 (enExample) | ||
| JP2012515221A5 (enExample) | ||
| JP2016520075A5 (enExample) | ||
| JP2019501920A5 (enExample) | ||
| JP2013531679A5 (enExample) | ||
| JP2019509311A5 (enExample) | ||
| AR100268A1 (es) | Formulación líquida que comprende compuesto neutralizante de gm-csf | |
| HRP20220011T1 (hr) | Nova stabilna formulacija za fxia protutijela | |
| JP2020015742A5 (enExample) | ||
| US20170112903A1 (en) | Lyophilized pharmaceutical composition of fc-peptide fusion protein | |
| JP2015517484A5 (enExample) | ||
| CN115803055A (zh) | 一种抗pd-1单克隆抗体液体制剂 |