JP2017514812A5 - - Google Patents
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- JP2017514812A5 JP2017514812A5 JP2016563404A JP2016563404A JP2017514812A5 JP 2017514812 A5 JP2017514812 A5 JP 2017514812A5 JP 2016563404 A JP2016563404 A JP 2016563404A JP 2016563404 A JP2016563404 A JP 2016563404A JP 2017514812 A5 JP2017514812 A5 JP 2017514812A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410174890.8 | 2014-04-29 | ||
| CN201410174890 | 2014-04-29 | ||
| PCT/CN2015/077887 WO2015165413A1 (zh) | 2014-04-29 | 2015-04-29 | 一种新型的稳定型抗体药物耦联物及其制备方法和用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019215918A Division JP7100617B2 (ja) | 2014-04-29 | 2019-11-29 | 新規安定型抗体薬物複合体の作製およびその応用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017514812A JP2017514812A (ja) | 2017-06-08 |
| JP2017514812A5 true JP2017514812A5 (https=) | 2017-07-20 |
| JP6666264B2 JP6666264B2 (ja) | 2020-03-13 |
Family
ID=54358190
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016563404A Active JP6666264B2 (ja) | 2014-04-29 | 2015-04-29 | 新規安定型抗体薬物複合体の作製およびその応用 |
| JP2019215918A Active JP7100617B2 (ja) | 2014-04-29 | 2019-11-29 | 新規安定型抗体薬物複合体の作製およびその応用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019215918A Active JP7100617B2 (ja) | 2014-04-29 | 2019-11-29 | 新規安定型抗体薬物複合体の作製およびその応用 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US11040084B2 (https=) |
| EP (2) | EP3138568B1 (https=) |
| JP (2) | JP6666264B2 (https=) |
| KR (1) | KR102511249B1 (https=) |
| CN (2) | CN106856656B (https=) |
| AU (2) | AU2015252518B2 (https=) |
| ES (1) | ES2736505T3 (https=) |
| WO (1) | WO2015165413A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6666264B2 (ja) | 2014-04-29 | 2020-03-13 | ジーンクアンタム ヘルスケア （スーチョウ） シーオー．， エルティーディー．Ｇｅｎｅｑｕａｎｔｕｍ Ｈｅａｌｔｈｃａｒｅ （Ｓｕｚｈｏｕ）Ｃｏ．， Ｌｔｄ． | 新規安定型抗体薬物複合体の作製およびその応用 |
| CN109843327B (zh) | 2016-07-07 | 2022-05-13 | 小利兰·斯坦福大学托管委员会 | 抗体佐剂缀合物 |
| WO2020190725A1 (en) | 2019-03-15 | 2020-09-24 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
| CN115175917A (zh) * | 2019-12-31 | 2022-10-11 | 启德医药科技（苏州）有限公司 | 药物缀合物及其应用 |
| US20230101266A1 (en) * | 2019-12-31 | 2023-03-30 | Genequantum Healthcare (Suzhou) Co., Ltd. | Anti-trop2 antibodies, antibody-drug conjugates, and application of the same |
| US20230399616A1 (en) * | 2020-10-30 | 2023-12-14 | Westlake Therapeutics (Hangzhou) Co. Limited | Modified Red Blood Cells and Uses Thereof for Delivering Agents |
| CN115867283A (zh) * | 2020-12-23 | 2023-03-28 | 启德医药科技（苏州）有限公司 | 包含开环硫代琥珀酰亚胺基团、寡肽片段和手性部分的新型异构化合物 |
| KR20230147105A (ko) | 2021-01-28 | 2023-10-20 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 리가제 융합 단백질 및 그 응용 |
| AU2022232674B2 (en) * | 2021-03-08 | 2025-08-28 | Brightgene Bio-Medical Technology Co., Ltd. | Anti-her2 antibody-immune agonist conjugate and applications thereof |
| KR102917231B1 (ko) | 2021-03-08 | 2026-01-26 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 항체 면역 작용제 접합체 및 이의 적용 |
| CN117177775A (zh) * | 2021-04-14 | 2023-12-05 | 启德医药科技（苏州）有限公司 | 连接子、缀合物及其应用 |
| TW202308700A (zh) * | 2021-04-29 | 2023-03-01 | 大陸商上海匯連生物醫藥有限公司 | 抗體偶聯藥物的製備方法及應用 |
| US11814394B2 (en) * | 2021-11-16 | 2023-11-14 | Genequantum Healthcare (Suzhou) Co., Ltd. | Exatecan derivatives, linker-payloads, and conjugates and thereof |
| WO2023104134A1 (en) * | 2021-12-09 | 2023-06-15 | Genequantum Healthcare (Suzhou) Co., Ltd. | Antibody-cytokine fusion proteins and applications thereof |
| WO2023185907A1 (en) * | 2022-03-29 | 2023-10-05 | Genequantum Healthcare (Suzhou) Co., Ltd. | A freeze-drying process for an ADC |
| EP4534090A1 (en) | 2022-06-02 | 2025-04-09 | Genequantum Healthcare (Suzhou) Co., Ltd. | Oligosaccharide linker, linker-supported material comprising oligosaccharide linker, antibody-drug conjugate having sugar chain remodeling, preparation method therefor and use thereof |
| CN119630427A (zh) * | 2022-06-28 | 2025-03-14 | 启德医药科技（苏州）有限公司 | 抗fgfr3抗体缀合物及其医疗用途 |
| AU2023296781A1 (en) | 2022-07-01 | 2025-02-13 | Genequantum Healthcare (Suzhou) Co., Ltd. | Immobilized endoglycosidase fusion protein and use thereof |
| AU2023305694A1 (en) * | 2022-07-15 | 2025-02-20 | Genequantum Healthcare (Suzhou) Co., Ltd. | Linkers, conjugates and applications thereof |
| IL318296A (en) | 2022-07-15 | 2025-03-01 | Genequantum Healthcare Suzhou Co Ltd | Anti-TROP2 antibody and its conjugate |
| AU2023328010A1 (en) | 2022-08-25 | 2025-03-20 | Genequantum Healthcare (Suzhou) Co., Ltd. | Pharmaceutical composition of antibody drug conjugate |
| WO2024078612A1 (en) * | 2022-10-14 | 2024-04-18 | Genequantum Healthcare (Suzhou) Co., Ltd. | Linker-payload compound, conjugates and applications thereof |
| CN120957726A (zh) * | 2023-03-21 | 2025-11-14 | 启德医药科技（苏州）有限公司 | 抗体-药物偶联物与癌症疗法的组合及其用途 |
| WO2024199432A1 (en) * | 2023-03-30 | 2024-10-03 | Genequantum Healthcare (Suzhou) Co., Ltd. | Site-speicfic orthogonal bioconjugate modality and application thereof |
| KR20260027874A (ko) | 2023-04-13 | 2026-03-03 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 항체-약물 접합체와 항-pd-1 항체의 조합물 및 이의 용도 |
| WO2025149014A1 (en) | 2024-01-12 | 2025-07-17 | Genequantum Healthcare (Suzhou) Co., Ltd. | Pharmaceutical composition |
| WO2025255054A1 (en) * | 2024-06-03 | 2025-12-11 | Darbix Llc | Methods and compositions for oligonucleotide bioconjugation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2478912B1 (en) | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| US7241020B2 (en) * | 2003-11-20 | 2007-07-10 | Mirror Lite | High definition vehicular mirror |
| NZ579482A (en) * | 2004-06-01 | 2011-02-25 | Genentech Inc | Antibody drug conjugates and methods |
| SG189817A1 (en) * | 2008-04-30 | 2013-05-31 | Immunogen Inc | Potent conjugates and hydrophilic linkers |
| WO2010087994A2 (en) | 2009-01-30 | 2010-08-05 | Whitehead Institute For Biomedical Research | Methods for ligation and uses thereof |
| US9504756B2 (en) | 2012-05-15 | 2016-11-29 | Seattle Genetics, Inc. | Self-stabilizing linker conjugates |
| RU2661083C2 (ru) * | 2012-10-04 | 2018-07-11 | Иммуноджен, Инк. | Использование пвдф-мембраны для очистки конъюгатов клеточно-связывающий агент - цитотоксический агент |
| EP2777714A1 (en) | 2013-03-15 | 2014-09-17 | NBE-Therapeutics LLC | Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme |
| CN105722851A (zh) * | 2013-04-28 | 2016-06-29 | 秦刚 | 一种新型的连接子及其制备方法和用途 |
| JP6666264B2 (ja) | 2014-04-29 | 2020-03-13 | ジーンクアンタム ヘルスケア （スーチョウ） シーオー．， エルティーディー．Ｇｅｎｅｑｕａｎｔｕｍ Ｈｅａｌｔｈｃａｒｅ （Ｓｕｚｈｏｕ）Ｃｏ．， Ｌｔｄ． | 新規安定型抗体薬物複合体の作製およびその応用 |
| CN107828351B (zh) | 2016-09-15 | 2021-07-27 | E·I·内穆尔杜邦公司 | 用于粘合的导电糊料 |
| EP3821005A4 (en) | 2018-07-09 | 2022-10-26 | Genequantum Healthcare (Suzhou) Co., Ltd. | AGAINST TROPHOBLAST ANTIGEN 2 (TROP2) SPECIFIC ANTIBODIES |
| US20230101266A1 (en) | 2019-12-31 | 2023-03-30 | Genequantum Healthcare (Suzhou) Co., Ltd. | Anti-trop2 antibodies, antibody-drug conjugates, and application of the same |
| KR20230147105A (ko) | 2021-01-28 | 2023-10-20 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 리가제 융합 단백질 및 그 응용 |
| KR102942648B1 (ko) | 2021-02-09 | 2026-03-20 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 결합 장치 및 결합 화합물을 생성하는 방법 |
| KR102917231B1 (ko) | 2021-03-08 | 2026-01-26 | 진콴텀 헬스케어 (쑤저우) 씨오., 엘티디. | 항체 면역 작용제 접합체 및 이의 적용 |
| CN117177775A (zh) | 2021-04-14 | 2023-12-05 | 启德医药科技（苏州）有限公司 | 连接子、缀合物及其应用 |
-
2015
- 2015-04-29 JP JP2016563404A patent/JP6666264B2/ja active Active
- 2015-04-29 ES ES15786402T patent/ES2736505T3/es active Active
- 2015-04-29 CN CN201580023609.3A patent/CN106856656B/zh active Active
- 2015-04-29 EP EP15786402.6A patent/EP3138568B1/en active Active
- 2015-04-29 WO PCT/CN2015/077887 patent/WO2015165413A1/zh not_active Ceased
- 2015-04-29 AU AU2015252518A patent/AU2015252518B2/en active Active
- 2015-04-29 KR KR1020167033391A patent/KR102511249B1/ko active Active
- 2015-04-29 US US15/307,738 patent/US11040084B2/en active Active
- 2015-04-29 EP EP19157398.9A patent/EP3517114A1/en not_active Withdrawn
- 2015-10-09 CN CN202110225700.0A patent/CN112999362B/zh active Active
-
2019
- 2019-11-29 JP JP2019215918A patent/JP7100617B2/ja active Active
-
2020
- 2020-02-11 AU AU2020200975A patent/AU2020200975B2/en active Active
-
2021
- 2021-02-19 US US17/180,645 patent/US11911435B2/en active Active
- 2021-02-19 US US17/180,412 patent/US11911434B2/en active Active
-
2024
- 2024-01-10 US US18/408,826 patent/US20240156894A1/en active Pending
- 2024-01-11 US US18/410,200 patent/US20240165192A1/en active Pending
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