JP2017513812A5 - - Google Patents
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- Publication number
- JP2017513812A5 JP2017513812A5 JP2016554400A JP2016554400A JP2017513812A5 JP 2017513812 A5 JP2017513812 A5 JP 2017513812A5 JP 2016554400 A JP2016554400 A JP 2016554400A JP 2016554400 A JP2016554400 A JP 2016554400A JP 2017513812 A5 JP2017513812 A5 JP 2017513812A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- compound
- antigen
- combination
- structural formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461945922P | 2014-02-28 | 2014-02-28 | |
| US61/945,922 | 2014-02-28 | ||
| PCT/CA2015/000131 WO2015127548A1 (en) | 2014-02-28 | 2015-02-27 | Tc-ptp inhibitors as apc activators for immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017513812A JP2017513812A (ja) | 2017-06-01 |
| JP2017513812A5 true JP2017513812A5 (enExample) | 2018-04-12 |
Family
ID=54008089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554400A Pending JP2017513812A (ja) | 2014-02-28 | 2015-02-27 | 免疫療法用のａｐｃ活性剤としてのｔｃ−ｐｔｐ阻害剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9828399B2 (enExample) |
| EP (1) | EP3110824A4 (enExample) |
| JP (1) | JP2017513812A (enExample) |
| CN (1) | CN106471004A (enExample) |
| CA (1) | CA2977839C (enExample) |
| WO (1) | WO2015127548A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| JP2017524348A (ja) * | 2014-06-10 | 2017-08-31 | モナッシュ ユニバーシティ | 養子細胞移入のためのｐｔｐｎ２阻害を用いた白血球の産生方法 |
| JP7653759B2 (ja) | 2016-01-20 | 2025-03-31 | フェイト セラピューティクス，インコーポレイテッド | 養子免疫療法における免疫細胞調節のための組成物および方法 |
| AU2017210031C1 (en) * | 2016-01-20 | 2020-11-26 | Fate Therapeutics, Inc. | Compositions and methods for immune cell modulation in adoptive immunotherapies |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| AU2018219226B2 (en) | 2017-02-07 | 2024-12-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| JP2020517259A (ja) | 2017-04-19 | 2020-06-18 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 操作された抗原受容体を発現する免疫細胞 |
| CN107652277A (zh) * | 2017-08-09 | 2018-02-02 | 江苏工程职业技术学院 | 一种依帕列净的制备方法 |
| WO2019036815A1 (en) * | 2017-08-24 | 2019-02-28 | The Royal Institution For The Advancement Of Learning/Mcgill University | ENHANCEMENT OF CD8 + T LYMPHOCYTES FOR ADOPTIVE CELL THERAPY BY INHIBITING PTPN1 (PTP1B) AND PTPN2 (TC-PTP)) |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP2021512875A (ja) * | 2018-02-02 | 2021-05-20 | カースゲン セラピューティクス カンパニー リミテッドＣａｒｓｇｅｎ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｃｏ．， Ｌｔｄ． | 細胞免疫療法の組み合わせ |
| AU2019218729B2 (en) | 2018-02-06 | 2025-12-04 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific CARs exhibiting optimal T cell function against FL-PLE labelled tumors |
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| EP3765094A4 (en) | 2018-03-15 | 2021-12-22 | KSQ Therapeutics, Inc. | GENE REGULATORY COMPOSITIONS AND PROCEDURES FOR IMPROVED IMMUNOTHERAPY |
| TWI888352B (zh) | 2018-06-21 | 2025-07-01 | 美商嘉來克生命科學有限責任公司 | 蛋白質酪胺酸磷酸酯酶抑制劑及其使用方法 |
| WO2019243537A1 (en) * | 2018-06-21 | 2019-12-26 | Universiteit Gent | Method for the in vitro differentiation and maturation of dendritic cells for therapeutic use |
| US20220081691A1 (en) * | 2018-08-07 | 2022-03-17 | Dana-Farber Cancer Institute, Inc | Modulating ptpn2 to increase immune responses and perturbing gene expression in hematopoietic stem cell lineages |
| SG11202105190SA (en) * | 2018-11-19 | 2021-06-29 | 11949098 Canada Inc | 4,5,6,7-tetrahydro-l-benzothiophene modulators of retinoic acid receptor related (rar) orphan nuclear receptors (rors) |
| KR102983496B1 (ko) | 2019-03-14 | 2026-06-29 | 칼리코 라이프 사이언시스 엘엘씨 | 단백질 티로신 포스파타제 억제제 및 이의 사용 방법 |
| KR20220009941A (ko) * | 2019-03-26 | 2022-01-25 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | Stat3의 저분자 분해제 |
| WO2020205467A1 (en) | 2019-03-29 | 2020-10-08 | The Regents Of The University Of Michigan | Stat3 protein degraders |
| AU2020401376A1 (en) * | 2019-12-12 | 2022-06-30 | Kumquat Biosciences Inc. | Compositions and methods for potentiating immune activity |
| IL295063A (en) | 2020-02-04 | 2022-09-01 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Chimeric antigen receptors (car) against dinitrophenol |
| WO2024243441A1 (en) | 2023-05-24 | 2024-11-28 | Kumquat Biosciences Inc. | Heterocyclic compounds and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9919673D0 (en) * | 1999-08-20 | 1999-10-20 | Cancer Res Campaign Tech | 2-Arlybenzazole compounds |
| EP1542997B1 (en) * | 2002-07-24 | 2012-02-29 | Dermira (Canada), Inc. | Pyrazolylbenzothiazole derivatives and their use as therapeutic agents |
| NZ554783A (en) | 2004-11-15 | 2010-12-24 | Ceptyr Inc | Protein tyrosine phosphatase inhibitors and methods of use thereof |
| EP1676834A1 (en) * | 2004-12-30 | 2006-07-05 | Sanofi-Aventis Deutschland GmbH | Fused bicyclic carboxamide derivates for use as CXCR2 inhibitors in the treatment of inflammation |
| WO2007081755A2 (en) * | 2006-01-09 | 2007-07-19 | Metabasis Therapeutics, Inc. | Indole-benzimidazole and indazole inhibitors of tyrosine phosphatases |
| US8168815B2 (en) * | 2007-01-26 | 2012-05-01 | Kaneq Pharma Inc. | Fused aromatic PTP-1B inhibitors |
| MX359399B (es) * | 2011-04-28 | 2018-09-27 | Novartis Ag | Inhibidores de 17alfa-hidroxilasa/c17-20-liasa. |
-
2015
- 2015-02-27 CA CA2977839A patent/CA2977839C/en active Active
- 2015-02-27 WO PCT/CA2015/000131 patent/WO2015127548A1/en not_active Ceased
- 2015-02-27 EP EP15755646.5A patent/EP3110824A4/en not_active Withdrawn
- 2015-02-27 JP JP2016554400A patent/JP2017513812A/ja active Pending
- 2015-02-27 US US15/122,031 patent/US9828399B2/en not_active Expired - Fee Related
- 2015-02-27 CN CN201580023358.9A patent/CN106471004A/zh active Pending
-
2017
- 2017-09-20 US US15/709,688 patent/US10005804B2/en active Active
-
2018
- 2018-05-22 US US15/986,313 patent/US10150787B2/en active Active
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