JP2017513473A5 - - Google Patents
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- JP2017513473A5 JP2017513473A5 JP2016561787A JP2016561787A JP2017513473A5 JP 2017513473 A5 JP2017513473 A5 JP 2017513473A5 JP 2016561787 A JP2016561787 A JP 2016561787A JP 2016561787 A JP2016561787 A JP 2016561787A JP 2017513473 A5 JP2017513473 A5 JP 2017513473A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cells
- derived
- hydrogel composition
- induced pluripotent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000017 hydrogel Substances 0.000 claims 15
- 239000000203 mixture Substances 0.000 claims 15
- 210000001671 embryonic stem cell Anatomy 0.000 claims 14
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 210000002889 endothelial cell Anatomy 0.000 claims 7
- 102000004196 processed proteins & peptides Human genes 0.000 claims 7
- 239000011230 binding agent Substances 0.000 claims 6
- 230000015572 biosynthetic process Effects 0.000 claims 6
- 230000021164 cell adhesion Effects 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 210000005239 tubule Anatomy 0.000 claims 5
- 210000002237 B-cell of pancreatic islet Anatomy 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 210000001130 astrocyte Anatomy 0.000 claims 4
- 210000004413 cardiac myocyte Anatomy 0.000 claims 4
- 210000000274 microglia Anatomy 0.000 claims 4
- 210000005155 neural progenitor cell Anatomy 0.000 claims 4
- 210000002569 neuron Anatomy 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 210000000844 retinal pigment epithelial cell Anatomy 0.000 claims 4
- XQQUSYWGKLRJRA-RABCQHRBSA-N (2s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s,3s)-2-amino-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-3-methylbutanoic acid Chemical compound CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(O)=O XQQUSYWGKLRJRA-RABCQHRBSA-N 0.000 claims 3
- MWOGMBZGFFZBMK-LJZWMIMPSA-N (2s)-2-[[(2s)-2-[[2-[[(2s,3s)-2-[[(2s)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid Chemical compound NC(N)=NCCC[C@@H](C(O)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1 MWOGMBZGFFZBMK-LJZWMIMPSA-N 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 108010069848 AG 73 Proteins 0.000 claims 3
- 108010045325 cyclic arginine-glycine-aspartic acid peptide Proteins 0.000 claims 3
- 108010088381 isoleucyl-lysyl-valyl-alanyl-valine Proteins 0.000 claims 3
- JFNLZVQOOSMTJK-KNVOCYPGSA-N norbornene Chemical compound C1[C@@H]2CC[C@H]1C=C2 JFNLZVQOOSMTJK-KNVOCYPGSA-N 0.000 claims 3
- 108010052768 tyrosyl-isoleucyl-glycyl-seryl-arginine Proteins 0.000 claims 3
- 201000008808 Fibrosarcoma Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 230000002491 angiogenic effect Effects 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 239000006143 cell culture medium Substances 0.000 claims 2
- 210000001612 chondrocyte Anatomy 0.000 claims 2
- 230000003511 endothelial effect Effects 0.000 claims 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 210000003494 hepatocyte Anatomy 0.000 claims 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 2
- 210000003668 pericyte Anatomy 0.000 claims 2
- 210000001626 skin fibroblast Anatomy 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 210000003606 umbilical vein Anatomy 0.000 claims 2
- 238000004132 cross linking Methods 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461978032P | 2014-04-10 | 2014-04-10 | |
| US61/978,032 | 2014-04-10 | ||
| PCT/US2015/025473 WO2015157732A1 (en) | 2014-04-10 | 2015-04-10 | Hydrogel compositions for use in promoting tubulogenesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020002977A Division JP2020078309A (ja) | 2014-04-10 | 2020-01-10 | 細管形成を促進するためのヒドロゲル組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017513473A JP2017513473A (ja) | 2017-06-01 |
| JP2017513473A5 true JP2017513473A5 (enExample) | 2018-05-17 |
Family
ID=54264594
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561787A Pending JP2017513473A (ja) | 2014-04-10 | 2015-04-10 | 細管形成を促進するためのヒドロゲル組成物 |
| JP2016561792A Pending JP2017513474A (ja) | 2014-04-10 | 2015-04-10 | 細胞伸長および分化における使用のためのヒドロゲル組成物 |
| JP2020002977A Ceased JP2020078309A (ja) | 2014-04-10 | 2020-01-10 | 細管形成を促進するためのヒドロゲル組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561792A Pending JP2017513474A (ja) | 2014-04-10 | 2015-04-10 | 細胞伸長および分化における使用のためのヒドロゲル組成物 |
| JP2020002977A Ceased JP2020078309A (ja) | 2014-04-10 | 2020-01-10 | 細管形成を促進するためのヒドロゲル組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (4) | US10195313B2 (enExample) |
| EP (2) | EP3129494B1 (enExample) |
| JP (3) | JP2017513473A (enExample) |
| WO (2) | WO2015157737A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10150948B2 (en) * | 2013-12-11 | 2018-12-11 | The Regents Of The University Of California | Compositions and methods for producing and administering brown adipocytes |
| JP7297408B2 (ja) | 2015-02-06 | 2023-06-26 | セル アイディーエックス， インコーポレイテッド | 抗原をカップリングさせた免疫試薬 |
| WO2017036533A1 (en) | 2015-09-03 | 2017-03-09 | Ecole Polytechnique Federale De Lausanne (Epfl) | Three-dimensional hydrogels for culturing adult epithelial stem cells and organoids |
| JP6714343B2 (ja) * | 2015-11-04 | 2020-06-24 | 田畑 泰彦 | 多能性幹細胞の培養方法 |
| US20200292944A1 (en) | 2015-11-18 | 2020-09-17 | Massachusetts Institute Of Technology | Method of making a patterned hydrogel and kit to make it |
| CN108368481A (zh) * | 2015-12-28 | 2018-08-03 | 日本瑞翁株式会社 | 培养细胞的分化促进方法以及培养细胞分化促进剂 |
| JP7130919B2 (ja) * | 2016-03-11 | 2022-09-06 | 三菱瓦斯化学株式会社 | 生体物質固定化方法 |
| US20190298851A1 (en) * | 2016-06-01 | 2019-10-03 | The Texas A&M University System | Sequential click reactions for the synthesis and functionalization of hydrogel microspheres and substrates |
| CN109716130B (zh) * | 2016-07-18 | 2023-05-23 | 赛尔伊迪克斯公司 | 抗原偶联的杂交试剂 |
| KR102350656B1 (ko) * | 2017-02-17 | 2022-01-12 | (주)옵토레인 | 면역진단 카트리지 |
| WO2018168955A1 (ja) * | 2017-03-15 | 2018-09-20 | メカノジェニック株式会社 | 細胞のｉｎ ｖｉｖｏでの特性を反映した細胞の反応の評価 |
| EP3630151B1 (en) * | 2017-05-30 | 2025-12-17 | Stem Pharm, Incorporated | Visible light polymerization of polyethylene glycol (peg) hydrogels |
| US10927148B2 (en) * | 2017-11-06 | 2021-02-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Wet adhesive peptide materials and their use |
| WO2019094389A1 (en) * | 2017-11-08 | 2019-05-16 | The Regents Of The University Of Colorado, A Body Corporate | Biodegradable biomimetics of growth plate cartilage for the treatment of physeal injuries |
| JP2021506319A (ja) * | 2017-12-22 | 2021-02-22 | アンスティテュ・パストゥール | ヒドロゲル型の生体機能チップマイクロ流体デバイス |
| WO2019195256A1 (en) * | 2018-04-04 | 2019-10-10 | Board Of Regents, The University Of Texas System | Biodegradable elastic hydrogels for bioprinting |
| US10875891B2 (en) * | 2018-05-13 | 2020-12-29 | Mackay Memorial Hospital | Short synthetic peptide and uses thereof |
| US11090651B2 (en) | 2018-05-31 | 2021-08-17 | University Of Washington | Fluidic patterning of hydrogel partitions |
| JP7384167B2 (ja) * | 2018-09-28 | 2023-11-21 | 日本ゼオン株式会社 | 心毒性評価方法 |
| CN109593704B (zh) * | 2019-01-31 | 2022-02-11 | 北京华龛生物科技有限公司 | 一种三维微载体细胞吸附培养的方法 |
| US12123026B2 (en) * | 2019-04-02 | 2024-10-22 | Wisconsin Alumni Research Foundation | Human pluripotent stem cell-derived brain organoids for cancer modeling and drug screening |
| US12454108B2 (en) | 2019-11-06 | 2025-10-28 | Innovega, Inc. | Apparatuses and methods for multistage molding of lenses |
| US11426959B2 (en) * | 2019-11-06 | 2022-08-30 | Innovega, Inc. | Apparatuses and methods for multistage molding of lenses |
| WO2021247749A1 (en) * | 2020-06-02 | 2021-12-09 | Cornell University | Methods for expanding hematopoietic stem cells |
| CN115043969B (zh) * | 2021-03-08 | 2024-03-29 | 中国科学院理化技术研究所 | 一种具有表面图案化的凝胶、制备方法和用途 |
| US11813604B2 (en) * | 2021-05-10 | 2023-11-14 | Trustees Of Boston University | Printed biogel nanosensors |
| CN116650728B (zh) * | 2023-05-26 | 2025-09-16 | 浙江大学 | 一种具有可加快内皮细胞迁移的拓扑微结构的产品及其制备方法和应用 |
| WO2025165903A1 (en) * | 2024-01-29 | 2025-08-07 | Wisconsin Alumni Research Foundation | Bioinspired synthetic hydrogel for gastrointestinal cancer organoid modeling |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7902121B2 (en) * | 2001-07-02 | 2011-03-08 | The Board Of Trustees Of The Leland Stanford Junior University | MHC-antigen arrays for detection and characterization of immune responses |
| US20060134781A1 (en) * | 2004-12-07 | 2006-06-22 | Bacterin International, Inc. | Three-dimensional cell culture system |
| US8062890B2 (en) * | 2005-08-15 | 2011-11-22 | Wisconsin Alumni Research Foundation | Defined surfaces of self-assembled monolayers and stem cells |
| US20100015709A1 (en) * | 2006-02-10 | 2010-01-21 | Trustees Of The University Of Pennsylvania | Regulating Stem Cell Differentiation By Controlling 2D and 3D Matrix Elasticity |
| US20070217019A1 (en) * | 2006-03-16 | 2007-09-20 | Wen-Kuei Huang | Optical components array device, microlens array and process of fabricating thereof |
| US9297005B2 (en) * | 2009-04-13 | 2016-03-29 | President And Fellows Of Harvard College | Harnessing cell dynamics to engineer materials |
| US20100291045A1 (en) * | 2009-05-15 | 2010-11-18 | University Of Delaware | Dynamic vibrational method and device for vocal fold tissue growth |
| CA2780490C (en) | 2009-11-10 | 2021-01-26 | The Johns Hopkins University | Hydrogel-based vascular lineage cell growth media and uses thereof |
| KR101067827B1 (ko) * | 2010-03-19 | 2011-09-27 | 포항공과대학교 산학협력단 | 3차원 인공 지지체 및 그 제조방법 |
| US20110269231A1 (en) * | 2010-04-22 | 2011-11-03 | Wisconsin Alumni Research Foundation | Proteoglycan-binding peptides that modulate stem cell behavior |
| US8778869B2 (en) * | 2010-06-09 | 2014-07-15 | Wisconsin Alumni Research Foundation | Tissue regeneration system |
| WO2011156686A2 (en) | 2010-06-11 | 2011-12-15 | The Regents Of The University Of Colorado, A Body Corporate | Method for synthesizing a cyclic multivalent peptide using a thiol-mediated reaction |
| US9315772B2 (en) | 2010-06-22 | 2016-04-19 | Universite De Rouen | Crosslinked hyaluronan hydrogels for 3D cell culture |
| WO2012045824A1 (en) | 2010-10-08 | 2012-04-12 | Solvay (Société Anonyme) | A bioactive amino acid sequence and use therefrom |
| US9234171B2 (en) | 2010-12-08 | 2016-01-12 | Rutgers, The State University Of New Jersey | Stem cell differentiation using novel light-responsive hydrogels |
| CN103146572B (zh) * | 2011-12-07 | 2016-01-06 | 清华大学 | 一种实现细胞集落均质性生长的装置和方法 |
| US8642516B2 (en) | 2012-05-07 | 2014-02-04 | Wisconsin Alumni Research Foundation | Chemically-defined arrays for screening cell-substrate interactions |
| EP2666486A1 (en) * | 2012-05-25 | 2013-11-27 | Université de Mons | Micro-engineered hydrogels |
| EP2684601B1 (en) * | 2012-07-13 | 2019-11-20 | Karlsruher Institut für Technologie | Formation of droplet or hydrogel arrays using hydrophilic-hydrophobic patterned surfaces for high-throughput screening applications |
| US9402710B2 (en) | 2012-07-16 | 2016-08-02 | The Board Of Trustees For The Leland Stanford Junior University | Macroporous 3-D scaffolds for tissue engineering |
| WO2014027042A2 (en) * | 2012-08-17 | 2014-02-20 | Amsilk Gmbh | Use of self-assembling polypeptides as tissue adhesives |
| KR101311325B1 (ko) * | 2012-09-13 | 2013-09-30 | 이상재 | 합성 디자인된 3차원 미세환경 구조물 |
| WO2014052458A1 (en) * | 2012-09-25 | 2014-04-03 | Yale University | Differentiation of human ips cells to human alveolar type ii via definitive endoderm |
| CN103864900A (zh) * | 2014-03-28 | 2014-06-18 | 甘少磊 | 一种诱导成骨短肽及其制备方法和用途 |
-
2014
- 2014-07-24 US US14/339,938 patent/US10195313B2/en active Active
-
2015
- 2015-04-10 WO PCT/US2015/025479 patent/WO2015157737A1/en not_active Ceased
- 2015-04-10 EP EP15775947.3A patent/EP3129494B1/en active Active
- 2015-04-10 JP JP2016561787A patent/JP2017513473A/ja active Pending
- 2015-04-10 EP EP15777338.3A patent/EP3129465B1/en active Active
- 2015-04-10 WO PCT/US2015/025473 patent/WO2015157732A1/en not_active Ceased
- 2015-04-10 US US14/684,120 patent/US9683213B2/en active Active
- 2015-04-10 US US14/684,062 patent/US9688957B2/en active Active
- 2015-04-10 JP JP2016561792A patent/JP2017513474A/ja active Pending
-
2017
- 2017-05-16 US US15/596,529 patent/US20170246357A1/en not_active Abandoned
-
2020
- 2020-01-10 JP JP2020002977A patent/JP2020078309A/ja not_active Ceased
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