JP2017512829A5 - - Google Patents
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- Publication number
- JP2017512829A5 JP2017512829A5 JP2017500412A JP2017500412A JP2017512829A5 JP 2017512829 A5 JP2017512829 A5 JP 2017512829A5 JP 2017500412 A JP2017500412 A JP 2017500412A JP 2017500412 A JP2017500412 A JP 2017500412A JP 2017512829 A5 JP2017512829 A5 JP 2017512829A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- aryl
- groups
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 32
- 125000003118 aryl group Chemical group 0.000 claims 23
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 18
- 125000000217 alkyl group Chemical group 0.000 claims 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 12
- 125000003545 alkoxy group Chemical group 0.000 claims 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 10
- 125000005843 halogen group Chemical group 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
- 125000004432 carbon atom Chemical group C* 0.000 claims 9
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 8
- 125000002877 alkyl aryl group Chemical group 0.000 claims 8
- 125000001072 heteroaryl group Chemical group 0.000 claims 8
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 229910052757 nitrogen Inorganic materials 0.000 claims 7
- 239000012453 solvate Substances 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 239000001257 hydrogen Substances 0.000 claims 6
- 125000005309 thioalkoxy group Chemical group 0.000 claims 5
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical group C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 claims 4
- 125000005213 alkyl heteroaryl group Chemical group 0.000 claims 4
- 229910052799 carbon Inorganic materials 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 3
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 3
- 229910052731 fluorine Chemical group 0.000 claims 3
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 2
- 230000003712 anti-aging effect Effects 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 238000009938 salting Methods 0.000 claims 2
- 230000036560 skin regeneration Effects 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 239000012620 biological material Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- -1 cyclic acetal Chemical class 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 125000000879 imine group Chemical group 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 125000005545 phthalimidyl group Chemical group 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 0 *C1*COCC1 Chemical compound *C1*COCC1 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14305374.2 | 2014-03-17 | ||
| EP14305374 | 2014-03-17 | ||
| PCT/EP2015/055577 WO2015140178A1 (en) | 2014-03-17 | 2015-03-17 | Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017512829A JP2017512829A (ja) | 2017-05-25 |
| JP2017512829A5 true JP2017512829A5 (https=) | 2018-05-10 |
| JP6629285B2 JP6629285B2 (ja) | 2020-01-15 |
Family
ID=50397079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500412A Active JP6629285B2 (ja) | 2014-03-17 | 2015-03-17 | 生体材料及び微生物の保存及び保護のためのグリコペプチド誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10100088B2 (https=) |
| EP (1) | EP3119800B9 (https=) |
| JP (1) | JP6629285B2 (https=) |
| KR (1) | KR102335943B1 (https=) |
| CN (1) | CN106459122B (https=) |
| CA (1) | CA2942731C (https=) |
| WO (1) | WO2015140178A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3011449A1 (en) | 2016-01-27 | 2017-08-03 | Protokinetix Inc. | Use of anti-aging glycoprotein for enhancing survival of neurosensory precursor cells |
| US10744181B2 (en) | 2017-01-30 | 2020-08-18 | Tfchem | Glycopeptide derivatives for use in the treatment and/or prevention and/or attenuation of fibrosis diseases |
| EP3999024A1 (en) * | 2019-07-17 | 2022-05-25 | Tfchem | Glycopeptides increasing lipid synthesis |
| KR102274195B1 (ko) | 2019-12-04 | 2021-07-08 | 고려대학교 산학협력단 | 자기 조립 화합물을 포함하는 항-동결 조성물 |
| WO2021179081A1 (en) * | 2020-03-10 | 2021-09-16 | Protokinetix Inc. | Use of anti-aging glycopeptides for treatment of dry eye disease, retinal degenerative diseases, or occular inflammation |
| CN117222655A (zh) * | 2021-01-20 | 2023-12-12 | Tf化学公司 | 环状糖氨基酸衍生物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2117640T3 (es) | 1990-01-17 | 1998-08-16 | Univ California | Composicion para mejorar la supervivencia de materiales biologicos. |
| FR2842810B1 (fr) | 2002-07-25 | 2006-01-27 | Inst Nat Sciences Appliq | Nouveaux composes gem difluores, leur procedes de preparation et leurs applications. |
| FR2878851B1 (fr) * | 2004-12-02 | 2007-02-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation en cryochirurgie et/ou cryopreservation |
| FR2900154B1 (fr) | 2006-04-25 | 2008-07-04 | Inst Nat Sciences Appliq | Nouveaux composes c-glycosides gem-difluores derives de la podophyllotoxine, leur preparation et leurs applications. |
| FR2900405B1 (fr) * | 2006-04-27 | 2013-11-29 | Inst Nat Sciences Appliq | Nouveaux composes c-glycosides monofluores, leurs procedes de preparation et leurs applications |
| FR2900656A1 (fr) * | 2006-05-03 | 2007-11-09 | Inst Nat Sciences Appliq | Composes c-glycopeptides gem-difluores, leur preparation et leur utilisation notamment pour la preservation de materiaux biologiques |
| CA2653153A1 (en) | 2008-02-07 | 2009-08-07 | University Of Ottawa | Antifreeze glycoprotein analogues and uses thereof |
| NZ613333A (en) | 2010-12-22 | 2015-01-30 | Tfchem | Derivatives of glyco-cf2-serine and glyco-cf2-threonine |
-
2015
- 2015-03-17 JP JP2017500412A patent/JP6629285B2/ja active Active
- 2015-03-17 WO PCT/EP2015/055577 patent/WO2015140178A1/en not_active Ceased
- 2015-03-17 US US15/125,725 patent/US10100088B2/en active Active
- 2015-03-17 CA CA2942731A patent/CA2942731C/en active Active
- 2015-03-17 EP EP15711716.9A patent/EP3119800B9/en active Active
- 2015-03-17 KR KR1020167028862A patent/KR102335943B1/ko active Active
- 2015-03-17 CN CN201580020405.4A patent/CN106459122B/zh active Active
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