JP2017508970A5 - - Google Patents
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- JP2017508970A5 JP2017508970A5 JP2016556777A JP2016556777A JP2017508970A5 JP 2017508970 A5 JP2017508970 A5 JP 2017508970A5 JP 2016556777 A JP2016556777 A JP 2016556777A JP 2016556777 A JP2016556777 A JP 2016556777A JP 2017508970 A5 JP2017508970 A5 JP 2017508970A5
- Authority
- JP
- Japan
- Prior art keywords
- biomarker
- biological sample
- time point
- psa
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 206010028980 Neoplasm Diseases 0.000 claims 33
- 239000000090 biomarker Substances 0.000 claims 33
- 239000012472 biological sample Substances 0.000 claims 22
- 238000000034 method Methods 0.000 claims 22
- 108010072866 Prostate-Specific Antigen Proteins 0.000 claims 19
- 102100038358 Prostate-specific antigen Human genes 0.000 claims 19
- 239000002131 composite material Substances 0.000 claims 19
- 201000011510 cancer Diseases 0.000 claims 15
- 206010060862 Prostate cancer Diseases 0.000 claims 13
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 13
- 102000000597 Growth Differentiation Factor 15 Human genes 0.000 claims 5
- 108010041834 Growth Differentiation Factor 15 Proteins 0.000 claims 5
- 238000005259 measurement Methods 0.000 claims 5
- 102100025142 Beta-microseminoprotein Human genes 0.000 claims 4
- 101000576812 Homo sapiens Beta-microseminoprotein Proteins 0.000 claims 4
- 101001050577 Homo sapiens Kinesin-like protein KIF2A Proteins 0.000 claims 3
- 102100023426 Kinesin-like protein KIF2A Human genes 0.000 claims 3
- 239000013068 control sample Substances 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000011156 evaluation Methods 0.000 claims 3
- 238000012360 testing method Methods 0.000 claims 3
- 238000001574 biopsy Methods 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000002405 diagnostic procedure Methods 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- RGJOEKWQDUBAIZ-IBOSZNHHSA-N CoASH Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS)O[C@H]1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 0.000 claims 1
- 108010007355 Glutathione S-Transferase pi Proteins 0.000 claims 1
- 102000007648 Glutathione S-Transferase pi Human genes 0.000 claims 1
- 102100030943 Glutathione S-transferase P Human genes 0.000 claims 1
- 101001010139 Homo sapiens Glutathione S-transferase P Proteins 0.000 claims 1
- 102100038356 Kallikrein-2 Human genes 0.000 claims 1
- 101710176220 Kallikrein-2 Proteins 0.000 claims 1
- 102000004879 Racemases and epimerases Human genes 0.000 claims 1
- 108090001066 Racemases and epimerases Proteins 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 102000009732 beta-microseminoprotein Human genes 0.000 claims 1
- 108010020169 beta-microseminoprotein Proteins 0.000 claims 1
- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 claims 1
- 239000005516 coenzyme A Substances 0.000 claims 1
- 229940093530 coenzyme a Drugs 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 108010043671 prostatic acid phosphatase Proteins 0.000 claims 1
- 238000012502 risk assessment Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1450274 | 2014-03-11 | ||
| SE1450274-4 | 2014-03-11 | ||
| SE1450420-3 | 2014-04-04 | ||
| SE1450420 | 2014-04-04 | ||
| PCT/SE2015/050272 WO2015137870A1 (en) | 2014-03-11 | 2015-03-11 | Method for detecting a solid tumor cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017508970A JP2017508970A (ja) | 2017-03-30 |
| JP2017508970A5 true JP2017508970A5 (enExample) | 2018-04-19 |
| JP6625061B2 JP6625061B2 (ja) | 2019-12-25 |
Family
ID=52829276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016556777A Expired - Fee Related JP6625061B2 (ja) | 2014-03-11 | 2015-03-11 | 固形腫瘍癌を検出する方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10451626B2 (enExample) |
| EP (2) | EP4220170A3 (enExample) |
| JP (1) | JP6625061B2 (enExample) |
| AU (2) | AU2015230017B2 (enExample) |
| CA (2) | CA3134289A1 (enExample) |
| DK (1) | DK3117216T3 (enExample) |
| FI (1) | FI3117216T3 (enExample) |
| RU (1) | RU2720148C9 (enExample) |
| WO (1) | WO2015137870A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101933752B1 (ko) | 2012-03-05 | 2018-12-28 | 오와이 아크틱 파트너스 에이비 | 전립선 암의 위험성 및 전립선 부피를 예측하는 방법 및 장치 |
| ES2964706T3 (es) | 2014-03-28 | 2024-04-09 | Opko Diagnostics Llc | Composiciones y métodos relacionados con el diagnóstico de cáncer de próstata |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| HUE055020T2 (hu) | 2015-03-27 | 2021-11-29 | Opko Diagnostics Llc | Prosztata-antigén szabványok és azok felhasználása |
| US11479878B2 (en) | 2016-03-16 | 2022-10-25 | Dana-Farber Cancer Institute, Inc. | Methods for genome characterization |
| EP3270163B1 (en) * | 2016-07-15 | 2018-09-05 | ProteoMediX AG | Method of detecting proteins in human samples and uses of such methods |
| CN110382718A (zh) * | 2017-02-01 | 2019-10-25 | 法迪亚股份有限公司 | 用于指示具有特定特征的个体中的前列腺癌的存在或不存在的方法 |
| US20210333265A1 (en) * | 2017-02-03 | 2021-10-28 | The Johns Hopkins University | Mini-cancers utilization for personalized cancer drug regimens |
| RU2664706C2 (ru) * | 2017-06-02 | 2018-08-21 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) | Способ прогнозирования клинического статуса рака предстательной железы |
| JP7127422B2 (ja) * | 2017-08-30 | 2022-08-30 | 東ソー株式会社 | 癌を検出する方法及び検出試薬 |
| WO2020205204A1 (en) * | 2019-04-03 | 2020-10-08 | Opko Diagnostics, Llc | Methods for the detection of prostate cancer |
| IT202000029948A1 (it) * | 2020-12-04 | 2022-06-04 | Nib Biotec S R L | Metodo per la diagnosi di tumore alla prostata in pazienti in differente fascia di età |
| KR20250107193A (ko) * | 2022-10-27 | 2025-07-11 | 마이옴, 인크. | 다수의 데이터 소스들을 조합하여 질병들의 조기 검출을 하기 위한 접근법 |
| WO2024092136A2 (en) * | 2022-10-28 | 2024-05-02 | Memorial Sloan-Kettering Cancer Center | Machine learning modeling for inpatient prediction |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030219840A1 (en) | 2002-05-24 | 2003-11-27 | Mikolajczyk Stephen D. | Method of analyzing proenzyme forms of prostate specific antigen in serum to improve prostate cancer detection |
| US20050277137A1 (en) | 2003-08-15 | 2005-12-15 | University Of Pittsburgh | Diagnostic multimarker serological profiling |
| KR100830811B1 (ko) * | 2006-09-18 | 2008-05-20 | 충북대학교 산학협력단 | 종양표시인자 검출용 바이오센서 |
| FR2934698B1 (fr) | 2008-08-01 | 2011-11-18 | Commissariat Energie Atomique | Procede de prediction pour le pronostic ou le diagnostic ou la reponse therapeutique d'une maladie et notamment du cancer de la prostate et dispositif permettant la mise en oeuvre du procede. |
| CA2750062A1 (en) | 2009-01-19 | 2010-07-22 | Katrin Stedronsky | Diagnostic assays for prostate cancer using psp94 and psa biomarkers |
| WO2010093939A2 (en) | 2009-02-12 | 2010-08-19 | Dana-Farber Cancer Institute, Inc. | Predicting and treating prostate cancer |
| EP2407555A1 (en) * | 2010-07-14 | 2012-01-18 | Fundació Institut de Recerca Hospital Universitari Vall d'Hebron, Fundació Privada | Methods and kits for the diagnosis of prostate cancer |
| WO2012031207A2 (en) | 2010-09-03 | 2012-03-08 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US20120202888A1 (en) | 2010-10-08 | 2012-08-09 | The Brigham And Women's Hospital, Inc. | Biomarkers of prostate cancer and predicting mortality |
| US20120150032A1 (en) | 2010-12-13 | 2012-06-14 | Julius Gudmundsson | Sequence Variants Associated with Prostate Specific Antigen Levels |
| AU2011352167A1 (en) | 2010-12-28 | 2013-07-11 | Caris Mpi, Inc. | Molecular profiling for cancer |
| CA2799163C (en) * | 2011-12-18 | 2025-01-07 | 20/20 Genesystems Inc | METHODS AND ALGORITHMS TO AID IN CANCER DETECTION |
| US20150094221A1 (en) | 2012-05-16 | 2015-04-02 | Phadia Ab | Method for Indicating the Presence or Non-Presence of Prostate Cancer |
| AU2013349801B2 (en) * | 2012-11-20 | 2019-03-07 | A3P Biomedical Ab | Method for indicating a presence or non-presence of aggressive prostate cancer |
| AU2013349721B2 (en) * | 2012-11-20 | 2019-03-28 | A3P Biomedical Ab | Prognostic method for individuals with prostate cancer |
-
2015
- 2015-03-11 EP EP23150294.9A patent/EP4220170A3/en active Pending
- 2015-03-11 CA CA3134289A patent/CA3134289A1/en active Pending
- 2015-03-11 CA CA2940445A patent/CA2940445C/en active Active
- 2015-03-11 FI FIEP15716168.8T patent/FI3117216T3/fi active
- 2015-03-11 WO PCT/SE2015/050272 patent/WO2015137870A1/en not_active Ceased
- 2015-03-11 JP JP2016556777A patent/JP6625061B2/ja not_active Expired - Fee Related
- 2015-03-11 AU AU2015230017A patent/AU2015230017B2/en active Active
- 2015-03-11 EP EP15716168.8A patent/EP3117216B1/en active Active
- 2015-03-11 DK DK15716168.8T patent/DK3117216T3/da active
- 2015-03-11 US US15/124,769 patent/US10451626B2/en active Active
- 2015-03-11 RU RU2016139491A patent/RU2720148C9/ru active
-
2021
- 2021-09-15 AU AU2021232712A patent/AU2021232712B2/en active Active
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