JP2016508026A5 - - Google Patents
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- JP2016508026A5 JP2016508026A5 JP2015542310A JP2015542310A JP2016508026A5 JP 2016508026 A5 JP2016508026 A5 JP 2016508026A5 JP 2015542310 A JP2015542310 A JP 2015542310A JP 2015542310 A JP2015542310 A JP 2015542310A JP 2016508026 A5 JP2016508026 A5 JP 2016508026A5
- Authority
- JP
- Japan
- Prior art keywords
- pca
- category
- composite value
- biomarker
- snppc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000090 biomarker Substances 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 18
- 102100038358 Prostate-specific antigen Human genes 0.000 claims description 16
- 102100040896 Growth/differentiation factor 15 Human genes 0.000 claims description 7
- 102100025142 Beta-microseminoprotein Human genes 0.000 claims description 6
- 101710194460 Growth/differentiation factor 15 Proteins 0.000 claims description 3
- 206010060862 Prostate cancer Diseases 0.000 claims description 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims description 3
- 239000002131 composite material Substances 0.000 claims 18
- 239000013068 control sample Substances 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 3
- 239000012472 biological sample Substances 0.000 claims 3
- XRIWLEWQNCECEP-UHFFFAOYSA-N 3-methyl-3-nitrososulfanyl-2-(propanoylamino)butanoic acid Chemical compound CCC(=O)NC(C(O)=O)C(C)(C)SN=O XRIWLEWQNCECEP-UHFFFAOYSA-N 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 102100026436 Regulator of MON1-CCZ1 complex Human genes 0.000 claims 1
- 101710180672 Regulator of MON1-CCZ1 complex Proteins 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 108010072866 Prostate-Specific Antigen Proteins 0.000 description 12
- 108010044434 Alpha-methylacyl-CoA racemase Proteins 0.000 description 4
- 102100040410 Alpha-methylacyl-CoA racemase Human genes 0.000 description 4
- 108010041834 Growth Differentiation Factor 15 Proteins 0.000 description 4
- 108010020169 beta-microseminoprotein Proteins 0.000 description 4
- 108010043671 prostatic acid phosphatase Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102100038356 Kallikrein-2 Human genes 0.000 description 3
- 101710176220 Kallikrein-2 Proteins 0.000 description 3
- 102100035703 Prostatic acid phosphatase Human genes 0.000 description 3
- 102000001708 Protein Isoforms Human genes 0.000 description 3
- 108010029485 Protein Isoforms Proteins 0.000 description 3
- 108010007355 Glutathione S-Transferase pi Proteins 0.000 description 2
- 102000007648 Glutathione S-Transferase pi Human genes 0.000 description 2
- 102100030943 Glutathione S-transferase P Human genes 0.000 description 2
- 101001010139 Homo sapiens Glutathione S-transferase P Proteins 0.000 description 2
- 101001001272 Homo sapiens Prostatic acid phosphatase Proteins 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 102000009732 beta-microseminoprotein Human genes 0.000 description 2
- 238000012217 deletion Methods 0.000 description 2
- 230000037430 deletion Effects 0.000 description 2
- 210000002307 prostate Anatomy 0.000 description 2
- 102000001399 Kallikrein Human genes 0.000 description 1
- 108060005987 Kallikrein Proteins 0.000 description 1
- 230000001689 kallikreinlike Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1251310-7 | 2012-11-20 | ||
| SE1251310 | 2012-11-20 | ||
| SE1350602 | 2013-05-16 | ||
| SE1350602-7 | 2013-05-16 | ||
| PCT/EP2013/074270 WO2014079874A1 (en) | 2012-11-20 | 2013-11-20 | Prognostic method for individuals with prostate cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016508026A JP2016508026A (ja) | 2016-03-17 |
| JP2016508026A5 true JP2016508026A5 (enExample) | 2017-01-05 |
Family
ID=49713059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015542310A Pending JP2016508026A (ja) | 2012-11-20 | 2013-11-20 | 前立腺癌を有する個体の予後診断方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10428385B2 (enExample) |
| EP (1) | EP2922970B1 (enExample) |
| JP (1) | JP2016508026A (enExample) |
| AU (1) | AU2013349721B2 (enExample) |
| CA (1) | CA2891394C (enExample) |
| ES (1) | ES2694409T3 (enExample) |
| RU (1) | RU2669809C2 (enExample) |
| WO (1) | WO2014079874A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102150771B1 (ko) | 2012-03-05 | 2020-09-01 | 오와이 아크틱 파트너스 에이비 | 전립선 암의 위험성 및 전립선 부피를 예측하는 방법 및 장치 |
| BR112015011359B1 (pt) | 2012-11-20 | 2022-12-06 | Phadia Ab | Método baseado em uma combinação redundantemente designada de dados para indicar uma presença ou não presença de câncer de próstata agressivo (pca) em um indivíduo, dispositivo de ensaio e kit de teste |
| AU2015230017B2 (en) * | 2014-03-11 | 2021-06-17 | A3P Biomedical Ab | Method for detecting a solid tumor cancer |
| EA201691952A1 (ru) | 2014-03-28 | 2017-05-31 | Опкоу Дайагностикс, Ллк. | Композиции и методы, имеющие отношение к диагностике рака предстательной железы |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| MX392040B (es) | 2015-03-27 | 2025-03-21 | Opko Diagnostics Llc | Estandares de antigeno prostatico y sus usos. |
| TWI766836B (zh) * | 2015-04-29 | 2022-06-11 | 美商Ｏｐｋｏ診斷法有限責任公司 | 用於主動監測前列腺癌之方法、電腦、系統及電腦可讀儲存媒體 |
| JP6570929B2 (ja) * | 2015-09-08 | 2019-09-04 | 国立研究開発法人農業・食品産業技術総合研究機構 | 特性推定モデル生成装置および方法、解析対象の特性推定装置および方法 |
| EP3577237B1 (en) * | 2017-02-01 | 2023-07-19 | Phadia AB | Method for indicating a presence or non-presence of prostate cancer in individuals with particular characteristics |
| WO2019144112A1 (en) * | 2018-01-22 | 2019-07-25 | Phadia Ab | Method for the harmonization of assay results |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582908B2 (en) * | 1990-12-06 | 2003-06-24 | Affymetrix, Inc. | Oligonucleotides |
| EP2522743A3 (en) | 2007-02-07 | 2013-08-07 | Decode Genetics EHF. | Genetic variants contributing to risk of prostate cancer |
| EP2611943B1 (en) * | 2010-09-03 | 2017-01-04 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| US20120202888A1 (en) | 2010-10-08 | 2012-08-09 | The Brigham And Women's Hospital, Inc. | Biomarkers of prostate cancer and predicting mortality |
| US20120150032A1 (en) * | 2010-12-13 | 2012-06-14 | Julius Gudmundsson | Sequence Variants Associated with Prostate Specific Antigen Levels |
| JP2015524052A (ja) | 2012-05-16 | 2015-08-20 | ファディア・アクチボラゲットＰｈａｄｉａ ＡＢ | 前立腺癌の存在または不存在の提示方法 |
| BR112015011359B1 (pt) | 2012-11-20 | 2022-12-06 | Phadia Ab | Método baseado em uma combinação redundantemente designada de dados para indicar uma presença ou não presença de câncer de próstata agressivo (pca) em um indivíduo, dispositivo de ensaio e kit de teste |
-
2013
- 2013-11-20 US US14/443,974 patent/US10428385B2/en active Active
- 2013-11-20 RU RU2015124008A patent/RU2669809C2/ru active
- 2013-11-20 WO PCT/EP2013/074270 patent/WO2014079874A1/en not_active Ceased
- 2013-11-20 EP EP13799501.5A patent/EP2922970B1/en active Active
- 2013-11-20 CA CA2891394A patent/CA2891394C/en active Active
- 2013-11-20 ES ES13799501.5T patent/ES2694409T3/es active Active
- 2013-11-20 AU AU2013349721A patent/AU2013349721B2/en active Active
- 2013-11-20 JP JP2015542310A patent/JP2016508026A/ja active Pending
-
2019
- 2019-09-19 US US16/575,940 patent/US20200010912A1/en not_active Abandoned
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