JP2017506506A - 抗血管新生薬への応答およびがんの予後の予測のための分子診断試験 - Google Patents

抗血管新生薬への応答およびがんの予後の予測のための分子診断試験 Download PDF

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JP2017506506A
JP2017506506A JP2016550631A JP2016550631A JP2017506506A JP 2017506506 A JP2017506506 A JP 2017506506A JP 2016550631 A JP2016550631 A JP 2016550631A JP 2016550631 A JP2016550631 A JP 2016550631A JP 2017506506 A JP2017506506 A JP 2017506506A
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sample
biomarker
expression
subject
score
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Japanese (ja)
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JP2017506506A5 (cg-RX-API-DMAC7.html
Inventor
デニス・ポール・ハーキン
リチャード・ケネディ
キャサリン・イー・キーティング
アンドリーナ・マッキャビガン
ローラ・エイ・ヒル
スティーブ・デハロ
ティモシー・デイビソン
フィオヌアラ・パターソン
シニード・ドネガン
ゲラ・ジェレマ
チャーリー・ゴウリー
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Almac Diagnostics Ltd
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Almac Diagnostics Ltd
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Publication of JP2017506506A publication Critical patent/JP2017506506A/ja
Publication of JP2017506506A5 publication Critical patent/JP2017506506A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2016550631A 2014-02-07 2015-02-09 抗血管新生薬への応答およびがんの予後の予測のための分子診断試験 Pending JP2017506506A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461937224P 2014-02-07 2014-02-07
US61/937,224 2014-02-07
GB1409479.1 2014-05-28
GBGB1409479.1A GB201409479D0 (en) 2014-05-28 2014-05-28 Molecular diagnostic test for cancer
PCT/GB2015/050352 WO2015118353A1 (en) 2014-02-07 2015-02-09 Molecular diagnostic test for predicting response to anti-angiogenic drugs and prognosis of cancer

Publications (2)

Publication Number Publication Date
JP2017506506A true JP2017506506A (ja) 2017-03-09
JP2017506506A5 JP2017506506A5 (cg-RX-API-DMAC7.html) 2018-03-15

Family

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JP2016550631A Pending JP2017506506A (ja) 2014-02-07 2015-02-09 抗血管新生薬への応答およびがんの予後の予測のための分子診断試験

Country Status (10)

Country Link
US (1) US10280468B2 (cg-RX-API-DMAC7.html)
EP (1) EP3102700A1 (cg-RX-API-DMAC7.html)
JP (1) JP2017506506A (cg-RX-API-DMAC7.html)
KR (1) KR20160117606A (cg-RX-API-DMAC7.html)
CN (1) CN106164296A (cg-RX-API-DMAC7.html)
AU (1) AU2015213844A1 (cg-RX-API-DMAC7.html)
BR (1) BR112016018044A2 (cg-RX-API-DMAC7.html)
CA (1) CA2938807A1 (cg-RX-API-DMAC7.html)
GB (1) GB201409479D0 (cg-RX-API-DMAC7.html)
WO (1) WO2015118353A1 (cg-RX-API-DMAC7.html)

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JP6899848B2 (ja) * 2016-12-28 2021-07-07 公益財団法人がん研究会 抗ｖｅｇｆｒ−２抗体医薬品の治療効果を予測するバイオマーカー、検査方法、及び検査キット
CN107301328B (zh) * 2017-05-19 2021-04-06 浙江工业大学 基于数据流聚类的癌症亚型精准发现与演化分析方法
KR102396784B1 (ko) 2017-06-13 2022-05-13 보스턴진 코포레이션 분자 기능적 프로파일을 생성하고, 시각화하고, 분류하는 시스템 및 방법
CN110880356A (zh) * 2018-09-05 2020-03-13 南京格致基因生物科技有限公司 对卵巢癌进行筛查、诊断或风险分级的方法和装置
US12325879B2 (en) * 2018-10-31 2025-06-10 Regents Of The University Of Minnesota Methods for predicting a response to bevacizumab or platinum-based chemotherapy or both in patients with ovarian cancer
US11610679B1 (en) 2020-04-20 2023-03-21 Health at Scale Corporation Prediction and prevention of medical events using machine-learning algorithms
CN112164474B (zh) * 2020-07-14 2024-05-24 中国矿业大学 一种基于自表达模型的药物敏感性预测方法
US12094582B1 (en) 2020-08-11 2024-09-17 Health at Scale Corporation Intelligent healthcare data fabric system
US12080428B1 (en) 2020-09-10 2024-09-03 Health at Scale Corporation Machine intelligence-based prioritization of non-emergent procedures and visits
AU2022245322A1 (en) * 2021-03-25 2023-10-05 Oncxerna Therapeutics, Inc. Targeted therapies in cancer
US20240115699A1 (en) * 2021-06-04 2024-04-11 Cedars-Sinai Medical Center Use of cancer cell expression of cadherin 12 and cadherin 18 to treat muscle invasive and metastatic bladder cancers
CN113667752A (zh) * 2021-09-09 2021-11-19 菲思特(上海)生物科技有限公司 一种用于柔红霉素代谢标志物的检测试剂盒及其检测方法和应用

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Publication number Priority date Publication date Assignee Title
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Also Published As

Publication number Publication date
US10280468B2 (en) 2019-05-07
US20170073761A1 (en) 2017-03-16
CA2938807A1 (en) 2015-08-13
CN106164296A (zh) 2016-11-23
BR112016018044A2 (pt) 2018-02-20
AU2015213844A1 (en) 2016-09-15
WO2015118353A1 (en) 2015-08-13
GB201409479D0 (en) 2014-07-09
EP3102700A1 (en) 2016-12-14
KR20160117606A (ko) 2016-10-10

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