JP2017505822A5 - - Google Patents

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Publication number
JP2017505822A5
JP2017505822A5 JP2016569114A JP2016569114A JP2017505822A5 JP 2017505822 A5 JP2017505822 A5 JP 2017505822A5 JP 2016569114 A JP2016569114 A JP 2016569114A JP 2016569114 A JP2016569114 A JP 2016569114A JP 2017505822 A5 JP2017505822 A5 JP 2017505822A5
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JP
Japan
Prior art keywords
group
psoriasis
pharmaceutically acceptable
complex according
complex
Prior art date
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Application number
JP2016569114A
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English (en)
Japanese (ja)
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JP2017505822A (ja
JP6445591B2 (ja
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Publication date
Priority claimed from HU1400075A external-priority patent/HUP1400075A2/hu
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Publication of JP2017505822A publication Critical patent/JP2017505822A/ja
Publication of JP2017505822A5 publication Critical patent/JP2017505822A5/ja
Application granted granted Critical
Publication of JP6445591B2 publication Critical patent/JP6445591B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016569114A 2014-02-14 2015-02-13 シロリムス及びその誘導体の複合体、それらの調製方法ならびにそれらを含有する医薬組成物 Expired - Fee Related JP6445591B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU1400075A HUP1400075A2 (hu) 2014-02-14 2014-02-14 Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói
HUP1400075 2014-02-14
PCT/IB2015/051086 WO2015121836A1 (en) 2014-02-14 2015-02-13 Complexes of sirolimus and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
JP2017505822A JP2017505822A (ja) 2017-02-23
JP2017505822A5 true JP2017505822A5 (OSRAM) 2018-04-05
JP6445591B2 JP6445591B2 (ja) 2018-12-26

Family

ID=89991398

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016569114A Expired - Fee Related JP6445591B2 (ja) 2014-02-14 2015-02-13 シロリムス及びその誘導体の複合体、それらの調製方法ならびにそれらを含有する医薬組成物

Country Status (14)

Country Link
US (1) US20170165237A1 (OSRAM)
EP (1) EP3104844B1 (OSRAM)
JP (1) JP6445591B2 (OSRAM)
CN (1) CN106456780A (OSRAM)
AU (1) AU2015216631B2 (OSRAM)
CA (1) CA2939602A1 (OSRAM)
ES (1) ES2784843T3 (OSRAM)
HK (1) HK1231416A1 (OSRAM)
HU (2) HUP1400075A2 (OSRAM)
IL (1) IL247239A0 (OSRAM)
PL (1) PL3104844T3 (OSRAM)
RU (1) RU2016136697A (OSRAM)
UA (1) UA120508C2 (OSRAM)
WO (1) WO2015121836A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008063563A2 (en) 2006-11-16 2008-05-29 Transderm, Inc. Methods of treating keratin hyperproliferation disorders using mtor inhibitors
WO2014117035A1 (en) 2013-01-24 2014-07-31 Transderm, Inc. COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS
US10383865B2 (en) 2016-04-25 2019-08-20 Druggability Technologies Ip Holdco Limited Pharmaceutical combination composition comprising complex formulations of Ivacaftor and Lumacaftor and their salts and derivatives, process for their preparation thereof and pharmaceutical compositions containing them
HUP1600270A2 (hu) * 2016-04-25 2017-10-30 Druggability Tech Ip Holdco Ltd Ivacaftornak, sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyszerészetileg elfogadott készítményei
HUP1600271A2 (hu) * 2016-04-25 2017-10-30 Druggability Tech Ip Holdco Ltd Ivacaftor és Lumacaftor sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyszerészetileg elfogadható készítményei
HUP1600269A2 (hu) * 2016-04-25 2017-10-30 Druggability Tech Ip Holdco Ltd Lumacaftornak, sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyászati készítményei
US10376501B2 (en) 2016-04-25 2019-08-13 Druggability Technologies Ip Holdco Limited Complexes of lumacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US20190167649A1 (en) * 2016-08-10 2019-06-06 The Board Of Regents Of The University Of Texas System Topical rapamycin therapy
CA3049402A1 (en) * 2017-01-06 2018-07-12 Palvella Therapeutics Llc Anhydrous compositions of mtor inhibitors and methods of use
CN110352062B (zh) * 2017-03-07 2024-04-02 豪夫迈·罗氏有限公司 免疫调节性大环内酯类的稳定制剂
US11000513B2 (en) 2018-07-02 2021-05-11 Palvella Therapeutics, Inc. Anhydrous compositions of mTOR inhibitors and methods of use
EP3927319A1 (en) * 2019-02-20 2021-12-29 AI Therapeutics, Inc. Topical rapamycin formulations and their use in treating facial angiofibromas and other skin disorders
AU2020277132B1 (en) * 2020-11-24 2021-11-04 Aft Pharmaceuticals Limited A Rapamycin Composition

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826689A (en) 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
AU5559890A (en) 1989-06-05 1991-01-07 Eric William Delf Improvements relating to exercise apparatus for the human body
US5286730A (en) 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory disease
ZA935110B (en) 1992-07-17 1994-02-04 Smithkline Beecham Corp Rapamycin derivatives
CH686761A5 (de) 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
CA2230748C (en) 1997-03-14 2010-08-03 American Home Products Corporation Rapamycin formulations for oral administration
GB9723669D0 (en) 1997-11-07 1998-01-07 Univ Aberdeen Skin penetration enhancing components
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US20030054042A1 (en) 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
GB0126253D0 (en) 2001-10-31 2002-01-02 Metris Therapeutics Ltd Treatment method
US7083802B2 (en) 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
AR045957A1 (es) 2003-10-03 2005-11-16 Novartis Ag Composicion farmaceutica y combinacion
AR050374A1 (es) 2004-08-20 2006-10-18 Wyeth Corp Forma polimorfica de rafampicina
JP2008530145A (ja) * 2005-02-15 2008-08-07 ワイス 経口投与可能なｃｃｉ−７７９製剤
US20080275076A1 (en) * 2005-03-08 2008-11-06 Per Holm Pharmaceutical Compositions Comprising Sirolimus and/or an Analogue Thereof
WO2006101972A2 (en) 2005-03-17 2006-09-28 Elan Pharma International Limited Injectable compositions of nanoparticulate immunosuppressive compounds
KR20080009196A (ko) 2005-04-12 2008-01-25 위스콘신 얼럼나이 리서어치 화운데이션 중합체 및 패신저 약물의 마이셀 조성물
WO2006123226A2 (en) 2005-05-18 2006-11-23 De Villiers, Malan An inhibitor of mtor for inhibiting the formation of scar tissue
US20070048350A1 (en) * 2005-08-31 2007-03-01 Robert Falotico Antithrombotic coating for drug eluting medical devices
BRPI0600285C1 (pt) 2006-01-13 2011-10-11 Brz Biotecnologia Ltda compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas
GB0602632D0 (en) 2006-02-08 2006-03-22 Pliva Istrazivacki Inst D O O Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus
US7812032B2 (en) 2006-07-25 2010-10-12 Abbott Laboratories Crystalline forms of rapamycin analogs
CN1919194A (zh) 2006-08-17 2007-02-28 刘瑜玲 西罗莫司的液体组合物
EP1938800A1 (en) 2006-12-06 2008-07-02 Ranbaxy Laboratories Limited Sirolimus nanodispersion
EP1952807A1 (en) * 2007-01-24 2008-08-06 LEK Pharmaceuticals D.D. Sirolimus formulation
CA3201293A1 (en) 2007-03-07 2008-09-12 Abraxis Bioscience, Llc Nanoparticle comprising rapamycin and albumin as anticancer agent
US20090130210A1 (en) 2007-09-11 2009-05-21 Raheja Praveen Pharmaceutical compositions of sirolimus
US20090068266A1 (en) 2007-09-11 2009-03-12 Raheja Praveen Sirolimus having specific particle size and pharmaceutical compositions thereof
HU230862B1 (hu) 2008-04-28 2018-10-29 DARHOLDING Vagyonkezelő Kft Berendezés és eljárás nanorészecskék folyamatos üzemű előállítására
US20100098770A1 (en) 2008-10-16 2010-04-22 Manikandan Ramalingam Sirolimus pharmaceutical formulations
GB0908129D0 (en) 2009-05-12 2009-06-24 Innovata Ltd Composition
WO2010146406A1 (en) 2009-06-19 2010-12-23 Nanoform Hungary Ltd. Nanoparticulate telmisartan compositions and process for the preparation thereof
HUP0900384A2 (en) 2009-06-19 2011-01-28 Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag Nanoparticulate olmesartan medoxomil compositions
HUP0900376A2 (en) * 2009-06-19 2011-01-28 Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag Nanoparticulate candesartan cilexetil composition
SG177281A1 (en) 2009-06-19 2012-02-28 Nanoform Hungary Ltd Nanostructured sildenafil base, its pharmaceutically acceptable salts and co-crystals, compositions of them, process for the preparation thereof and pharmaceutical compositions containing them
EP2480207B1 (en) 2009-09-25 2016-11-09 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
KR101267813B1 (ko) 2009-12-30 2013-06-04 주식회사 삼양바이오팜 향상된 수용해도를 갖는 라파마이신 함유 고분자나노입자 주사제형 조성물 및 그 제조방법, 및 방사선 요법과 병용하기 위한 항암 조성물
WO2011128910A2 (en) 2010-03-02 2011-10-20 Rpg Life Sciences Limited A drug delivery solid dosage formulation of sirolimus
WO2011135580A2 (en) * 2010-04-28 2011-11-03 Cadila Healthcare Limited Pharmaceutical compositions of sirolimus
EP2575889B1 (en) 2010-06-02 2015-04-22 Fresenius Kabi Oncology Ltd Stable pharmaceutical compositions of rapamycin esters
HUP1000325A2 (en) 2010-06-18 2012-01-30 Druggability Technologies Ip Holdco Jersey Ltd Nanostructured aprepitant compositions and process for their preparation
US20120022095A1 (en) 2010-06-24 2012-01-26 Teng Joyce M C Topical rapamycin for treatment of facial angiofibromas in tuberous sclerosis
IT1400977B1 (it) 2010-07-01 2013-07-05 Euticals Spa Nuovi complessi di inclusione farmaceutici, solidi, solubili in acqua e le loro soluzioni acquose per uso orale, oftalmico, topico o parenterale, contenenti un macrolide ed alcune ciclodestrine.
US20130102572A1 (en) 2011-04-12 2013-04-25 Dow Pharmaceutical Sciences Methods of treating skin conditions exhibiting telangiectasia
WO2013022201A1 (en) 2011-08-11 2013-02-14 Dong-A Pharm. Co., Ltd. Process of preparing a stabilized and solubilized formulation of sirolimus derivatives
KR101151890B1 (ko) * 2011-08-11 2012-05-31 동아제약주식회사 안정화 및 가용화된 시롤리무스 유도체 조성물의 제조방법
US8912215B2 (en) 2011-12-13 2014-12-16 Everon Biosciences, Inc. Rapamycin composition

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