JP2017504011A - 代謝物質パネルに基づく被験体において膵臓癌を診断するための手段および方法 - Google Patents

代謝物質パネルに基づく被験体において膵臓癌を診断するための手段および方法 Download PDF

Info

Publication number
JP2017504011A
JP2017504011A JP2016541297A JP2016541297A JP2017504011A JP 2017504011 A JP2017504011 A JP 2017504011A JP 2016541297 A JP2016541297 A JP 2016541297A JP 2016541297 A JP2016541297 A JP 2016541297A JP 2017504011 A JP2017504011 A JP 2017504011A
Authority
JP
Japan
Prior art keywords
pancreatic cancer
biomarker
sample
subject
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016541297A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017504011A5 (enExample
Inventor
カムラゲ，ビエテ
レスツカ，レジーナ
ペーター，エーリク
カストラー，ユルゲン
シャッツ，フィリップ
カルトホフ，ホルガー
シュニーヴィント，ボドー
マイヤール，ユリア
レルヒ，マルクス
ピラルスキ，クリスティアン
グリュッツマン，ロベルト
Original Assignee
メタノミクス ヘルス ゲーエムベーハー
メタノミクス ヘルス ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メタノミクス ヘルス ゲーエムベーハー, メタノミクス ヘルス ゲーエムベーハー filed Critical メタノミクス ヘルス ゲーエムベーハー
Publication of JP2017504011A publication Critical patent/JP2017504011A/ja
Publication of JP2017504011A5 publication Critical patent/JP2017504011A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08—Sphingolipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016541297A 2013-12-20 2014-12-19 代謝物質パネルに基づく被験体において膵臓癌を診断するための手段および方法 Pending JP2017504011A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13198959 2013-12-20
EP13198959.2 2013-12-20
PCT/EP2014/078765 WO2015091962A1 (en) 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Publications (2)

Publication Number Publication Date
JP2017504011A true JP2017504011A (ja) 2017-02-02
JP2017504011A5 JP2017504011A5 (enExample) 2018-02-08

Family

ID=49885030

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016541297A Pending JP2017504011A (ja) 2013-12-20 2014-12-19 代謝物質パネルに基づく被験体において膵臓癌を診断するための手段および方法

Country Status (7)

Country Link
US (1) US10168333B2 (enExample)
EP (2) EP3084443B1 (enExample)
JP (1) JP2017504011A (enExample)
AU (1) AU2014368412A1 (enExample)
CA (1) CA2934012A1 (enExample)
ES (1) ES2698374T3 (enExample)
WO (1) WO2015091962A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018518683A (ja) * 2015-06-25 2018-07-12 メタノミクス ヘルス ゲーエムベーハー バイオマーカーパネルに基づいて対象における膵癌を診断するための手段および方法
WO2018143336A1 (ja) * 2017-02-03 2018-08-09 住友化学株式会社 膵臓癌の検査方法

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160146727A (ko) * 2014-03-26 2016-12-21 메타노믹스 헬스 게엠베하 대사물 패널에 기초하여 혈액 샘플의 품질을 결정하기 위한 수단 및 방법
JP2017067510A (ja) * 2015-09-29 2017-04-06 花王株式会社 脂質の質量分析方法
KR101937531B1 (ko) 2016-09-28 2019-01-10 국립암센터 대장암 진단 장치와 대장암 진단 정보 제공 방법
CN110121647A (zh) * 2016-12-15 2019-08-13 得克萨斯大学体系董事会 用于检测和治疗胰腺导管腺癌的方法
EP3502699A1 (en) * 2017-12-20 2019-06-26 Metanomics Health GmbH Methods for diagnosing pancreatic cancer
US11181524B2 (en) * 2018-06-14 2021-11-23 Metabolomycs, Inc Metabolomic signatures for predicting, diagnosing, and prognosing various diseases including cancer
CN109288827B (zh) * 2018-09-29 2020-05-26 桂林医学院附属医院 神经酰胺酶抑制剂D-e-MAPP在制备改善急性胰腺炎的药物中的应用
ES2799973A1 (es) * 2019-06-19 2020-12-22 Univ Granada Panel de metabolitos como biomarcadores para el diagnostico de cancer de pancreas
WO2022140380A1 (en) * 2020-12-21 2022-06-30 Pancreomics Llc Metabolomic signatures for predicting, diagnosing, and prognosing chronic pancreatitis
WO2024059549A2 (en) * 2022-09-12 2024-03-21 Board Of Regents, The University Of Texas System Methods for the detection and treatment of pancreatic ductal adenocarcinoma
TWI859033B (zh) 2023-12-18 2024-10-11 安益藥業股份有限公司 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013079594A1 (en) * 2011-11-30 2013-06-06 Metanomics Health Gmbh Device and methods to diagnose pancreatic cancer
JP2013529784A (ja) * 2010-06-23 2013-07-22 ユニバーシティ オブ ルーイビル リサーチ ファウンデーション，インコーポレーテッド 癌を検出するための方法
WO2013172105A1 (ja) * 2012-05-18 2013-11-21 日東紡績株式会社 膵臓癌を検出するためのマーカー

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
AU2003218649B2 (en) 2002-02-28 2007-09-06 Metanomics Gmbh & Co. Kgaa Mass spectrometry method for analysing mixtures of substances
SG10201405975VA (en) * 2009-10-01 2014-11-27 Phenomenome Discoveries Inc Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis
EP2415877A3 (en) * 2010-02-17 2012-02-15 Deutsches Krebsforschungszentrum Means and methods for diagnosing pancreatic cancer
EP3355057A3 (en) 2010-06-01 2018-12-12 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013529784A (ja) * 2010-06-23 2013-07-22 ユニバーシティ オブ ルーイビル リサーチ ファウンデーション，インコーポレーテッド 癌を検出するための方法
WO2013079594A1 (en) * 2011-11-30 2013-06-06 Metanomics Health Gmbh Device and methods to diagnose pancreatic cancer
WO2013172105A1 (ja) * 2012-05-18 2013-11-21 日東紡績株式会社 膵臓癌を検出するためのマーカー

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018518683A (ja) * 2015-06-25 2018-07-12 メタノミクス ヘルス ゲーエムベーハー バイオマーカーパネルに基づいて対象における膵癌を診断するための手段および方法
WO2018143336A1 (ja) * 2017-02-03 2018-08-09 住友化学株式会社 膵臓癌の検査方法
JPWO2018143336A1 (ja) * 2017-02-03 2019-11-21 住友化学株式会社 膵臓癌の検査方法

Also Published As

Publication number Publication date
US10168333B2 (en) 2019-01-01
EP3084443B1 (en) 2018-08-22
ES2698374T3 (es) 2019-02-04
WO2015091962A1 (en) 2015-06-25
AU2014368412A1 (en) 2016-07-07
US20160313338A1 (en) 2016-10-27
EP3084443A1 (en) 2016-10-26
CA2934012A1 (en) 2015-06-25
EP3431998A1 (en) 2019-01-23

Similar Documents

Publication Publication Date Title
JP6286475B2 (ja) 対象において膵臓がんを診断する手段及び方法
JP6219300B2 (ja) 膵臓癌を診断するための装置及び方法
US10168333B2 (en) Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel
US20180180619A1 (en) Means and Methods for Diagnosing Pancreatic Cancer in a Subject Based on a Biomarker Panel
WO2019121942A1 (en) Methods for diagnosing pancreatic cancer
ES2717458T3 (es) Dispositivo y procedimientos para diagnosticar cáncer de páncreas

Legal Events

Date Code Title Description
RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20161118

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20161118

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171219

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20171219

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180912

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180925

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20190514

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20200107