CA2934012A1 - Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel - Google Patents

Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel Download PDF

Info

Publication number
CA2934012A1
CA2934012A1 CA2934012A CA2934012A CA2934012A1 CA 2934012 A1 CA2934012 A1 CA 2934012A1 CA 2934012 A CA2934012 A CA 2934012A CA 2934012 A CA2934012 A CA 2934012A CA 2934012 A1 CA2934012 A1 CA 2934012A1
Authority
CA
Canada
Prior art keywords
sphingomyelin
sample
biomarkers
plasma
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2934012A
Other languages
English (en)
French (fr)
Inventor
Beate Kamlage
Regina Reszka
Erik Peter
Jurgen Kastler
Philipp Schatz
Holger Kalthoff
Bodo Schniewind
Julia Mayerle
Markus Lerch
Christian Pilarsky
Robert Grutzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metanomics Health GmbH
Original Assignee
Metanomics Health GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metanomics Health GmbH filed Critical Metanomics Health GmbH
Publication of CA2934012A1 publication Critical patent/CA2934012A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08—Sphingolipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2934012A 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel Abandoned CA2934012A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13198959 2013-12-20
EP13198959.2 2013-12-20
PCT/EP2014/078765 WO2015091962A1 (en) 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Publications (1)

Publication Number Publication Date
CA2934012A1 true CA2934012A1 (en) 2015-06-25

Family

ID=49885030

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2934012A Abandoned CA2934012A1 (en) 2013-12-20 2014-12-19 Means and methods for diagnosing pancreatic cancer in a subject based on a metabolite panel

Country Status (7)

Country Link
US (1) US10168333B2 (enExample)
EP (2) EP3084443B1 (enExample)
JP (1) JP2017504011A (enExample)
AU (1) AU2014368412A1 (enExample)
CA (1) CA2934012A1 (enExample)
ES (1) ES2698374T3 (enExample)
WO (1) WO2015091962A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160146727A (ko) * 2014-03-26 2016-12-21 메타노믹스 헬스 게엠베하 대사물 패널에 기초하여 혈액 샘플의 품질을 결정하기 위한 수단 및 방법
JP2018518683A (ja) * 2015-06-25 2018-07-12 メタノミクス ヘルス ゲーエムベーハー バイオマーカーパネルに基づいて対象における膵癌を診断するための手段および方法
JP2017067510A (ja) * 2015-09-29 2017-04-06 花王株式会社 脂質の質量分析方法
KR101937531B1 (ko) 2016-09-28 2019-01-10 국립암센터 대장암 진단 장치와 대장암 진단 정보 제공 방법
CN110121647A (zh) * 2016-12-15 2019-08-13 得克萨斯大学体系董事会 用于检测和治疗胰腺导管腺癌的方法
US20190353659A1 (en) * 2017-02-03 2019-11-21 Sumitomo Chemical Company, Limited Pancreatic cancer detection method
EP3502699A1 (en) * 2017-12-20 2019-06-26 Metanomics Health GmbH Methods for diagnosing pancreatic cancer
US11181524B2 (en) * 2018-06-14 2021-11-23 Metabolomycs, Inc Metabolomic signatures for predicting, diagnosing, and prognosing various diseases including cancer
CN109288827B (zh) * 2018-09-29 2020-05-26 桂林医学院附属医院 神经酰胺酶抑制剂D-e-MAPP在制备改善急性胰腺炎的药物中的应用
ES2799973A1 (es) * 2019-06-19 2020-12-22 Univ Granada Panel de metabolitos como biomarcadores para el diagnostico de cancer de pancreas
WO2022140380A1 (en) * 2020-12-21 2022-06-30 Pancreomics Llc Metabolomic signatures for predicting, diagnosing, and prognosing chronic pancreatitis
WO2024059549A2 (en) * 2022-09-12 2024-03-21 Board Of Regents, The University Of Texas System Methods for the detection and treatment of pancreatic ductal adenocarcinoma
TWI859033B (zh) 2023-12-18 2024-10-11 安益藥業股份有限公司 一種診斷犬科動物胰臟炎的方法與試劑組與一種使用醯基肉鹼作為診斷犬科動物胰臟炎之用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
US5397894A (en) 1993-05-28 1995-03-14 Varian Associates, Inc. Method of high mass resolution scanning of an ion trap mass spectrometer
AU2003218649B2 (en) 2002-02-28 2007-09-06 Metanomics Gmbh & Co. Kgaa Mass spectrometry method for analysing mixtures of substances
SG10201405975VA (en) * 2009-10-01 2014-11-27 Phenomenome Discoveries Inc Serum-based biomarkers of pancreatic cancer and uses thereof for diseasedetection and diagnosis
EP2415877A3 (en) * 2010-02-17 2012-02-15 Deutsches Krebsforschungszentrum Means and methods for diagnosing pancreatic cancer
EP3355057A3 (en) 2010-06-01 2018-12-12 Metanomics Health GmbH Means and methods for diagnosing pancreatic cancer in a subject
EP3955004B1 (en) * 2010-06-23 2024-05-29 University of Louisville Research Foundation, Inc. Use of fatty acids in methods for detecting cancer
WO2013079594A1 (en) * 2011-11-30 2013-06-06 Metanomics Health Gmbh Device and methods to diagnose pancreatic cancer
WO2013172105A1 (ja) * 2012-05-18 2013-11-21 日東紡績株式会社 膵臓癌を検出するためのマーカー

Also Published As

Publication number Publication date
US10168333B2 (en) 2019-01-01
EP3084443B1 (en) 2018-08-22
JP2017504011A (ja) 2017-02-02
ES2698374T3 (es) 2019-02-04
WO2015091962A1 (en) 2015-06-25
AU2014368412A1 (en) 2016-07-07
US20160313338A1 (en) 2016-10-27
EP3084443A1 (en) 2016-10-26
EP3431998A1 (en) 2019-01-23

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20210309

FZDE Discontinued

Effective date: 20210309