JP2017503749A5 - - Google Patents
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- Publication number
- JP2017503749A5 JP2017503749A5 JP2016519779A JP2016519779A JP2017503749A5 JP 2017503749 A5 JP2017503749 A5 JP 2017503749A5 JP 2016519779 A JP2016519779 A JP 2016519779A JP 2016519779 A JP2016519779 A JP 2016519779A JP 2017503749 A5 JP2017503749 A5 JP 2017503749A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- cyclic
- acyclic
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361885384P | 2013-10-01 | 2013-10-01 | |
| US61/885,384 | 2013-10-01 | ||
| US201461934618P | 2014-01-31 | 2014-01-31 | |
| US61/934,618 | 2014-01-31 | ||
| PCT/US2014/058680 WO2015051030A2 (en) | 2013-10-01 | 2014-10-01 | Stabilized polypeptides and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017503749A JP2017503749A (ja) | 2017-02-02 |
| JP2017503749A5 true JP2017503749A5 (cg-RX-API-DMAC7.html) | 2018-08-30 |
Family
ID=52779285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016519779A Pending JP2017503749A (ja) | 2013-10-01 | 2014-10-01 | 安定化されたポリペプチドおよびその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160244494A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3052520A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2017503749A (cg-RX-API-DMAC7.html) |
| CN (1) | CN106103472A (cg-RX-API-DMAC7.html) |
| IL (1) | IL244810A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015051030A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
| CA2677045C (en) | 2007-01-31 | 2016-10-18 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
| CA2682174C (en) | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| WO2012021875A1 (en) | 2010-08-13 | 2012-02-16 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles with triazole linkers |
| CN108929375A (zh) | 2011-10-18 | 2018-12-04 | 爱勒让治疗公司 | 拟肽大环化合物 |
| CA2864120A1 (en) | 2012-02-15 | 2013-08-22 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| CN112500466B (zh) | 2012-02-15 | 2022-05-03 | 艾瑞朗医疗公司 | 拟肽大环化合物 |
| WO2014138429A2 (en) | 2013-03-06 | 2014-09-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating hif1alpha |
| JP6564369B2 (ja) | 2013-12-09 | 2019-08-21 | デュレクト コーポレイション | 薬学的活性剤複合体、ポリマー複合体、ならびにこれらを伴う組成物及び方法 |
| US10905739B2 (en) | 2014-09-24 | 2021-02-02 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| EP3197478A4 (en) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| SG11201707750YA (en) | 2015-03-20 | 2017-10-30 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| WO2017004548A1 (en) | 2015-07-01 | 2017-01-05 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| WO2018089648A2 (en) | 2016-11-09 | 2018-05-17 | Ohio State Innovation Foundation | Di-sulfide containing cell penetrating peptides and methods of making and using thereof |
| US11352394B2 (en) | 2016-11-22 | 2022-06-07 | Ohio State Innovation Foundation | Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof |
| US10913773B2 (en) | 2016-11-22 | 2021-02-09 | Ohio State Innovation Foundation | Bicyclic peptidyl inhibitor of tumor necrosis factor-alpha |
| BR112020004555A2 (pt) | 2017-09-07 | 2020-09-24 | Fog Pharmaceuticals, Inc. | agentes que modulam funções de beta-catenina e métodos dos mesmos |
| WO2019070962A1 (en) | 2017-10-04 | 2019-04-11 | Ohio State Innovation Foundation | BICYCLIC PEPTIDE INHIBITORS |
| AU2018385697B2 (en) | 2017-12-15 | 2023-11-09 | Dana-Farber Cancer Institute, Inc. | Stabilized peptide-mediated targeted protein degradation |
| WO2019136209A1 (en) * | 2018-01-05 | 2019-07-11 | President And Fellows Of Harvard College | Stabilized polypeptides and uses thereof |
| WO2019148195A2 (en) | 2018-01-29 | 2019-08-01 | Ohio State Innovation Foundation | Cyclic peptidyl inhibitors of cal-pdz binding domain |
| EP3749678A1 (en) | 2018-02-07 | 2020-12-16 | Dana Farber Cancer Institute, Inc. | Cell-permeable stapled peptide modules for cellular delivery |
| US11987647B2 (en) | 2018-05-09 | 2024-05-21 | Ohio State Innovation Foundation | Cyclic cell-penetrating peptides with one or more hydrophobic residues |
| US11091522B2 (en) | 2018-07-23 | 2021-08-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| CA3110082A1 (en) | 2018-08-20 | 2020-02-27 | Fog Pharmaceuticals, Inc. | Collections of peptides, peptide agents, and methods of use thereof |
| US20230174576A1 (en) * | 2020-10-30 | 2023-06-08 | Xeno-Interface Inc. | Beta-strand bridge peptide |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1282722B1 (en) * | 1999-10-15 | 2011-06-15 | Avatar Medical, L.L.C. | Stabilized proteins |
| WO2005044839A2 (en) * | 2003-11-05 | 2005-05-19 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| DK1689863T3 (da) * | 2003-11-15 | 2014-08-25 | Polyphor Ltd | Template-fikserede beta-hairpinloopmimetika og deres anvendelse i fag-display |
| US7202332B2 (en) * | 2004-05-27 | 2007-04-10 | New York University | Methods for preparing internally constrained peptides and peptidomimetics |
| US20060148715A1 (en) * | 2004-12-20 | 2006-07-06 | Baylor College Of Medicine | Structural requirements for STAT3 binding and recruitment to phosphotyrosine ligands |
| CA2682174C (en) * | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| US20110144306A1 (en) * | 2008-07-23 | 2011-06-16 | President And Fellows Of Harvard College | Ligation of stapled polypeptides |
| CA2768299C (en) * | 2009-07-13 | 2018-03-20 | President And Fellows Of Harvard College | Bifunctional stapled polypeptides and uses thereof |
| US20130177979A1 (en) * | 2010-06-22 | 2013-07-11 | University Of Central Florida Research Foundation, Inc. | Methods and compositions for cell permeable stat3 inhibitor |
-
2014
- 2014-10-01 WO PCT/US2014/058680 patent/WO2015051030A2/en not_active Ceased
- 2014-10-01 CN CN201480065507.3A patent/CN106103472A/zh active Pending
- 2014-10-01 US US15/026,473 patent/US20160244494A1/en not_active Abandoned
- 2014-10-01 EP EP14850442.6A patent/EP3052520A4/en not_active Withdrawn
- 2014-10-01 JP JP2016519779A patent/JP2017503749A/ja active Pending
-
2016
- 2016-03-29 IL IL244810A patent/IL244810A0/en unknown
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