JP2017503623A - 誘導血栓分散カテーテル - Google Patents
誘導血栓分散カテーテル Download PDFInfo
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- JP2017503623A JP2017503623A JP2016554544A JP2016554544A JP2017503623A JP 2017503623 A JP2017503623 A JP 2017503623A JP 2016554544 A JP2016554544 A JP 2016554544A JP 2016554544 A JP2016554544 A JP 2016554544A JP 2017503623 A JP2017503623 A JP 2017503623A
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Abstract
Description
本出願は、2013年11月18日に出願された米国仮出願第61/905,430号の優先権の利益を主張し、この仮出願は、参照により本明細書に援用される。
冠動脈血流予備能、冠血流予備量比、及びP−Vループは、動脈内の異なる位置で取られた測定値を必要とし得る。これらのパラメータのための測定値を提供するために、本発明のシステム及び方法は、脈管構造内の機能的流れセンサの大2の位置に対する機能的流れセンサの第1の位置での圧力および流量を評価する。例えば、第1の位置は、検査下の血管のセグメントの遠位であり、第2の位置は、血管のこのセグメントの近位である。2つの位置に渡って得られた測定値は次に、1又は複数の閾値に対して評価され、この閾値は、閉塞が体管腔内に存在するかどうかを決定するために使用され得る。
特許、特許出願、特許公開、雑誌、書籍、論文、ウェブコンテンツのような、他の文献の参照及び引用が、本開示の全体にわたって成されている。全てのこのような文献は、全ての目的のためにそれらの全体が参照により本明細書に援用される。
本発明の様々な修正形態及びそれらの多くのさらなる実施形態は、本明細書に図示され且つ記載されたものに加えて、本明細書で引用される科学文献及び特許文献への参照を含む、この文書の全内容から当業者に明らかになるであろう。本明細書の主題は、様々な実施形態及びそれらの均等物における本発明の実施に適合されることができる重要な情報、例証及び手引きを含む。
Claims (52)
- 体管腔を評価するとともにそこに治療を加えるためのカテーテルシステムであって:
第1の管腔を画定するとともに遠位部分を有する細長いボディ;
前記第1の管腔の中への挿入のために構成される内側部材であって、治療エネルギを治療部位に供給するように構成されるエネルギ源を有する、内側部材;及び
前記細長いボディの前記遠位部分に位置するイメージングアセンブリ;を有する、
カテーテルシステム。 - 前記エネルギ源は、音響エネルギ源である、
請求項1に記載のカテーテルシステム。 - 前記治療エネルギは、超音波エネルギである、
請求項1に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で並進移動するように構成される、
請求項1に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で回転するように構成される、
請求項1に記載のカテーテルシステム。 - 前記細長いボディは、前記細長いボディの前記遠位部分上の開口と前記細長いボディの近位部分上のポートとの間に流体経路を提供する供給管腔を画定する、
請求項1に記載のカテーテルシステム。 - 前記供給管腔は、前記細長いボディの前記遠位部分に位置する複数の開口と流体連通する、
請求項6に記載のカテーテルシステム。 - 前記体管腔の中の機能的流れデータを受信するように構成されるデータ収集装置をさらに有する、
請求項1に記載のカテーテルシステム。 - 前記データ収集装置は、フローセンサ、圧力センサ、及びそれらの組み合わせからなるグループから選択される、
請求項8に記載のカテーテルシステム。 - 前記イメージングアセンブリは、光音響トランスデューサ及び超音波トランスデューサからなるグループから選択される、
請求項1に記載のカテーテルシステム。 - 前記超音波トランスデューサは、アレイベースのトランスデューサである、
請求項10に記載のカテーテルシステム。 - 前記超音波トランスデューサは、前方視トランスデューサである、
請求項10に記載のカテーテルシステム。 - 前記内側部材は、第2のイメージングアセンブリを有する、
請求項1に記載のカテーテルシステム。 - 血管を評価するための及びそこに治療を加えるための方法であって:
カテーテルシステムを提供するステップであって、
第1の管腔を画定するとともに遠位部分を有する細長いボディ;
前記第1の管腔の中に移動可能に配置される内側部材であって、治療エネルギを供給するように構成されるエネルギ源を有する、内側部材;及び
前記細長いボディの前記遠位部分に位置するイメージングアセンブリ;を有する、
カテーテルシステムを提供するステップ;
カテーテルシステムを血管の中に導入するステップ;
前記血管の中の生物学的材料を撮像するステップ;並びに
前記エネルギ源により、治療エネルギを前記生物学的材料に供給するステップ;を有する、
方法。 - 前記供給するステップの後に前記血管を撮像するステップをさらに有する、
請求項14に記載の方法。 - 前記生物学的材料に血栓溶解剤を供給するステップをさらに有する、
請求項14に記載の方法。 - 前記血栓溶解剤は、前記細長いボディの供給管腔を通って運ばれ、前記細長いボディの前記遠位部分上に位置する開口を通って前記生物学的材料に供給される、
請求項16に記載の方法。 - 前記カテーテルシステムは、前記細長いボディの前記遠位部分に位置するデータ収集装置をさらに有し、前記方法は、前記データ収集装置により、前記血管の中の機能的流れ測定値を得るステップをさらに有する、
請求項14に記載の方法。 - 前記データ収集装置は、フローセンサ、圧力センサ、又はそれらの組み合わせからなるグループから選択される、
請求項18に記載の方法。 - 前記エネルギ源は、音響エネルギ源である、
請求項14に記載の方法。 - 前記治療エネルギは、超音波エネルギである、
請求項14に記載の方法。 - 前記治療エネルギを供給しながら、前記細長いボディの前記第1の管腔の中で前記内側部材を並進移動させるステップをさらに有する、
請求項14に記載の方法。 - 前記治療エネルギを供給しながら、前記細長いボディの前記第1の管腔の中で前記内側部材を回転させるステップをさらに有する、
請求項14に記載の方法。 - 体管腔を評価するとともにそこに治療を加えるためのカテーテルシステムであって:
第1の管腔を画定するとともに遠位部分を有する細長いボディ;
前記第1の管腔の中への挿入のために構成される内側部材であって、治療エネルギを治療部位に供給するように構成されるエネルギ源を有する、内側部材;及び
前記細長いボディの前記遠位部分に位置する圧力センサ;を有する、
カテーテルシステム。 - 前記エネルギ源は、音響エネルギ源である、
請求項24に記載のカテーテルシステム。 - 前記治療エネルギは、超音波エネルギである、
請求項24に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で並進移動するように構成される、
請求項24に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で回転するように構成される、
請求項24に記載のカテーテルシステム。 - 前記細長いボディは、前記細長いボディの前記遠位部分に位置する開口と前記細長いボディの近位部分上のポートとの間に流体経路を提供する供給管腔を画定する、
請求項24に記載のカテーテルシステム。 - 前記供給管腔は、前記細長いボディの前記遠位部分で複数の開口と流体連通する、
請求項29に記載のカテーテルシステム。 - 前記圧力センサは、血流、血圧、又はそれらの組み合わせを測定するように構成される、
請求項24に記載のカテーテルシステム。 - 前記圧力センサは、機能的血流を測定するように構成される、
請求項31に記載のカテーテルシステム。 - 前記体管腔の表面を撮像するように構成されるイメージングアセンブリをさらに有する、
請求項24に記載のカテーテルシステム。 - 前記イメージングアセンブリは、光音響トランスデューサ及び超音波トランスデューサからなるグループから選択される、
請求項33に記載のカテーテルシステム。 - 前記超音波トランスデューサは、アレイベースのトランスデューサである、
請求項33に記載のカテーテルシステム。 - 前記超音波トランスデューサは、前方視トランスデューサである、
請求項33に記載のカテーテルシステム。 - 前記圧力センサは、微小電気機械(MEMS)圧力センサである、
請求項24に記載のカテーテルシステム。 - 前記細長いボディの前記遠位部分に位置するフローセンサをさらに有する、
請求項24に記載のカテーテルシステム。 - 体管腔を評価するとともにそこに治療を加えるためのカテーテルシステムであって:
第1の管腔を画定するとともに遠位部分を有する細長いボディ;
前記第1の管腔の中への挿入のために構成される内側部材であって、治療エネルギを治療部位に供給するように構成されるエネルギ源を有する、内側部材;及び
前記細長いボディの前記遠位部分に位置するフローセンサ;を有する、
カテーテルシステム。 - 前記エネルギ源は、音響エネルギ源である、
請求項39に記載のカテーテルシステム。 - 前記治療エネルギは、超音波エネルギである、
請求項39に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で並進移動するように構成される、
請求項39に記載のカテーテルシステム。 - 前記内側部材は、前記治療エネルギを供給しながら、前記細長いボディの中で回転するように構成される、
請求項39に記載のカテーテルシステム。 - 前記細長いボディは、前記細長いボディの前記遠位部分に位置する開口と前記細長いボディの近位部分上のポートとの間に流体経路を提供する供給管腔を画定する、
請求項39に記載のカテーテルシステム。 - 前記供給管腔は、前記細長いボディの前記遠位部分で複数の開口と流体連通する、
請求項44に記載のカテーテルシステム。 - 前記フローセンサは、ドップラフローセンサである、
請求項39に記載のカテーテルシステム。 - 前記フローセンサは、機能的血流を測定するように構成される、
請求項46に記載のカテーテルシステム。 - 前記体管腔の表面を撮像するように構成されるイメージングアセンブリをさらに有する、
請求項39に記載のカテーテルシステム。 - 前記イメージングアセンブリは、光音響トランスデューサ及び超音波トランスデューサからなるグループから選択される、
請求項48に記載のカテーテルシステム。 - 前記超音波トランスデューサは、アレイベースのトランスデューサである、
請求項48に記載のカテーテルシステム。 - 前記超音波トランスデューサは、前方視トランスデューサである、
請求項48に記載のカテーテルシステム。 - 前記フローセンサは、圧電トランスデューサを有する、
請求項39に記載のカテーテルシステム。
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EP3076881B1 (en) | 2022-01-05 |
EP3076881A4 (en) | 2017-01-04 |
WO2015074032A1 (en) | 2015-05-21 |
CN105744902A (zh) | 2016-07-06 |
JP6517832B2 (ja) | 2019-05-22 |
US11890025B2 (en) | 2024-02-06 |
EP3076881A1 (en) | 2016-10-12 |
US20160287278A1 (en) | 2016-10-06 |
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