JP2017503473A5 - - Google Patents
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- JP2017503473A5 JP2017503473A5 JP2016521718A JP2016521718A JP2017503473A5 JP 2017503473 A5 JP2017503473 A5 JP 2017503473A5 JP 2016521718 A JP2016521718 A JP 2016521718A JP 2016521718 A JP2016521718 A JP 2016521718A JP 2017503473 A5 JP2017503473 A5 JP 2017503473A5
- Authority
- JP
- Japan
- Prior art keywords
- pore
- target polynucleotide
- polynucleotide
- fractional
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020195453A JP7349972B2 (ja) | 2013-11-26 | 2020-11-25 | ポリヌクレオチド配列決定のための組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361909316P | 2013-11-26 | 2013-11-26 | |
| US61/909,316 | 2013-11-26 | ||
| PCT/US2014/067582 WO2015081178A1 (en) | 2013-11-26 | 2014-11-26 | Compositions and methods for polynucleotide sequencing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020195453A Division JP7349972B2 (ja) | 2013-11-26 | 2020-11-25 | ポリヌクレオチド配列決定のための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017503473A JP2017503473A (ja) | 2017-02-02 |
| JP2017503473A5 true JP2017503473A5 (https=) | 2020-07-16 |
| JP6800749B2 JP6800749B2 (ja) | 2020-12-23 |
Family
ID=52424089
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016521718A Active JP6800749B2 (ja) | 2013-11-26 | 2014-11-26 | ポリヌクレオチド配列決定のための組成物及び方法 |
| JP2020195453A Active JP7349972B2 (ja) | 2013-11-26 | 2020-11-25 | ポリヌクレオチド配列決定のための組成物及び方法 |
| JP2023088480A Pending JP2023116553A (ja) | 2013-11-26 | 2023-05-30 | ポリヌクレオチド配列決定のための組成物及び方法 |
| JP2025017268A Pending JP2025072503A (ja) | 2013-11-26 | 2025-02-05 | ポリヌクレオチド配列決定のための組成物及び方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020195453A Active JP7349972B2 (ja) | 2013-11-26 | 2020-11-25 | ポリヌクレオチド配列決定のための組成物及び方法 |
| JP2023088480A Pending JP2023116553A (ja) | 2013-11-26 | 2023-05-30 | ポリヌクレオチド配列決定のための組成物及び方法 |
| JP2025017268A Pending JP2025072503A (ja) | 2013-11-26 | 2025-02-05 | ポリヌクレオチド配列決定のための組成物及び方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US9689033B2 (https=) |
| EP (3) | EP3556869B1 (https=) |
| JP (4) | JP6800749B2 (https=) |
| CN (2) | CN113528632A (https=) |
| AU (3) | AU2014354726B2 (https=) |
| CA (2) | CA2926871C (https=) |
| DK (2) | DK3074534T3 (https=) |
| ES (2) | ES2958715T3 (https=) |
| FI (1) | FI3556869T3 (https=) |
| LT (1) | LT3074534T (https=) |
| SI (1) | SI3074534T1 (https=) |
| WO (2) | WO2015081178A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0905140D0 (en) | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| EP3663412B1 (en) | 2011-09-23 | 2022-03-09 | Oxford Nanopore Technologies PLC | Analysis of a polymer comprising polymer units by means of translocation through a nanopore |
| BR112014020211A2 (pt) | 2012-02-16 | 2017-07-04 | Oxford Nanopore Tech Ltd | métodos para analisar uma série ordenada por tempo de medições de um polímero, para estimar a presença, ausência ou quantidade de um polímero alvo, e para determinar uma alteração em um polímero, programa de computador, e, dispositivos de análise e de diagnóstico |
| JP6271505B2 (ja) | 2012-04-10 | 2018-01-31 | オックスフォード ナノポール テクノロジーズ リミテッド | 変異体ライセニンポア |
| US10213746B2 (en) | 2016-04-14 | 2019-02-26 | Lockheed Martin Corporation | Selective interfacial mitigation of graphene defects |
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
| EP3556869B1 (en) * | 2013-11-26 | 2023-08-02 | Illumina Inc. | Compositions and methods for polynucleotide sequencing |
| JP6749243B2 (ja) | 2014-01-22 | 2020-09-02 | オックスフォード ナノポール テクノロジーズ リミテッド | 1つまたは複数のポリヌクレオチド結合タンパク質を標的ポリヌクレオチドに付着させる方法 |
| ES3035698T3 (en) * | 2014-02-19 | 2025-09-08 | Univ Washington | Nanopore-based analysis of protein characteristics |
| US10443097B2 (en) | 2014-05-02 | 2019-10-15 | Oxford Nanopore Technologies Ltd. | Method of improving the movement of a target polynucleotide with respect to a transmembrane pore |
| US10400014B2 (en) | 2014-09-01 | 2019-09-03 | Oxford Nanopore Technologies Ltd. | Mutant CsgG pores |
| EP3971300B1 (en) * | 2014-10-16 | 2024-06-05 | Oxford Nanopore Technologies plc | Sorting of polymers |
| EP3334840A1 (en) * | 2015-08-10 | 2018-06-20 | Stratos Genomics, Inc. | Single molecule nucleic acid sequencing with molecular sensor complexes |
| JP2018533010A (ja) * | 2015-10-21 | 2018-11-08 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | ナノポアベースのdna配列決定のための脂質二重層形成を支援するための撥水性層としてのフルオロポリマーの使用 |
| AU2017225374B2 (en) | 2016-03-02 | 2020-03-05 | Oxford Nanopore Technologies Limited | Mutant pore |
| WO2017174990A1 (en) | 2016-04-06 | 2017-10-12 | Oxford Nanopore Technologies Limited | Mutant pore |
| EP3475447B1 (en) * | 2016-06-23 | 2021-04-21 | F. Hoffmann-La Roche AG | Formation and calibration of nanopore sequencing cells |
| WO2018029108A1 (en) | 2016-08-08 | 2018-02-15 | F. Hoffmann-La Roche Ag | Basecalling for stochastic sequencing processes |
| US20180127816A1 (en) | 2016-10-19 | 2018-05-10 | Illumina, Inc. | Methods for chemical ligation of nucleic acids |
| GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
| WO2019002893A1 (en) | 2017-06-30 | 2019-01-03 | Vib Vzw | NEW PROTEIN PORES |
| CA3067230A1 (en) * | 2017-09-15 | 2019-03-21 | Illumina, Inc. | Tuning and calibration features of a sequence-detection system |
| JP2020530257A (ja) * | 2017-09-15 | 2020-10-22 | イルミナ インコーポレイテッド | 配列検出システム |
| US10310959B2 (en) | 2017-11-07 | 2019-06-04 | Bank Of America Corporation | Pre-deployment validation system using intelligent databases |
| JP7377222B2 (ja) * | 2018-06-21 | 2023-11-09 | エフ. ホフマン-ラ ロシュ アーゲー | 配列決定のためのトンネル接合部 |
| EP3814529A1 (en) * | 2018-06-26 | 2021-05-05 | Electronic Biosciences Inc. | Controlled nanopore translocation utilizing extremophilic replication proteins |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| JP2020031557A (ja) * | 2018-08-28 | 2020-03-05 | 株式会社日立ハイテクノロジーズ | 生体分子分析装置 |
| WO2020084705A1 (ja) * | 2018-10-24 | 2020-04-30 | 株式会社日立ハイテク | 生体ポリマ分析デバイス及びそれを用いた分析装置、並びに分析方法 |
| GB201907244D0 (en) * | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| WO2021056598A1 (zh) | 2019-09-29 | 2021-04-01 | 北京齐碳科技有限公司 | 一种Mmup单体变体及其应用 |
| EP4061965A1 (en) * | 2019-11-19 | 2022-09-28 | Rijksuniversiteit Groningen | Artificial nanopores and uses and methods relating thereto |
| NL2024579B1 (en) * | 2019-12-24 | 2021-09-06 | Univ Delft Tech | Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes |
| CN114807317A (zh) * | 2021-01-22 | 2022-07-29 | 上海羿鸣生物科技有限公司 | 一种优化的dna线性扩增方法及试剂盒 |
| GB202107192D0 (en) * | 2021-05-19 | 2021-06-30 | Oxford Nanopore Tech Ltd | Method |
| CN113322180B (zh) * | 2021-05-31 | 2022-07-15 | 中国科学院物理研究所 | 基于纳米孔测序的力谱分析方法和分析装置 |
| WO2023164728A2 (en) * | 2022-02-28 | 2023-08-31 | Rajant Health Incorporated | Systems and methods for alignment-free variant calling |
| IL320502A (en) | 2022-10-28 | 2025-06-01 | Univ Groningen | Nanopore-based protein efflux |
| EP4698646A2 (en) * | 2023-04-21 | 2026-02-25 | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 1475 North Scottsdale Road | Novel transmembrane sensors and method of characterization for lysis-free detection of intracellular targets |
| WO2026073207A1 (en) | 2024-09-30 | 2026-04-02 | Illumina, Inc. | Affinity-binder-based assay compositions and methods |
| CN119639558B (zh) * | 2024-12-13 | 2025-09-26 | 杭州海兰时生物科技有限责任公司 | 一种用于单细胞测序的液滴融合系统 |
Family Cites Families (32)
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| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5508179A (en) | 1994-03-18 | 1996-04-16 | Bio-Rad Laboratories, Inc. | Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions |
| US5795782A (en) * | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| JP2003502166A (ja) | 1999-06-22 | 2003-01-21 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 固体状態の次元的特徴の制御 |
| US6913884B2 (en) | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
| EP1990428B1 (en) | 2000-02-07 | 2010-12-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
| WO2008102120A1 (en) | 2007-02-20 | 2008-08-28 | Oxford Nanopore Technologies Limited | Lipid bilayer sensor system |
| WO2010004265A1 (en) * | 2008-07-07 | 2010-01-14 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
| CA3092369C (en) | 2008-09-22 | 2025-09-23 | University Of Washington | MSP NANOPORES AND ASSOCIATED PROCESSES |
| GB0905140D0 (en) * | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| EP2614156B1 (en) * | 2010-09-07 | 2018-08-01 | The Regents of The University of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
| EP3385992B1 (en) | 2011-07-27 | 2024-09-04 | The Board of Trustees of the University of Illinois | Nanopore sensors for biomolecular characterization |
| JP6226869B2 (ja) * | 2011-10-21 | 2017-11-08 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素法 |
| US9617591B2 (en) | 2011-12-29 | 2017-04-11 | Oxford Nanopore Technologies Ltd. | Method for characterising a polynucleotide by using a XPD helicase |
| BR112014016112B8 (pt) | 2011-12-29 | 2022-12-27 | Oxford Nanopore Tech Ltd | Método e aparelho para caracterizar um polinucleotídeo alvo, kit, e, uso de uma helicase |
| JP5809572B2 (ja) | 2012-01-30 | 2015-11-11 | ルネサスエレクトロニクス株式会社 | 半導体装置 |
| JP6271505B2 (ja) | 2012-04-10 | 2018-01-31 | オックスフォード ナノポール テクノロジーズ リミテッド | 変異体ライセニンポア |
| US9116118B2 (en) * | 2012-06-08 | 2015-08-25 | Pacific Biosciences Of California, Inc. | Modified base detection with nanopore sequencing |
| EP2875128B8 (en) * | 2012-07-19 | 2020-06-24 | Oxford Nanopore Technologies Limited | Modified helicases |
| EP3556869B1 (en) * | 2013-11-26 | 2023-08-02 | Illumina Inc. | Compositions and methods for polynucleotide sequencing |
-
2014
- 2014-11-26 EP EP19161148.2A patent/EP3556869B1/en active Active
- 2014-11-26 US US14/554,741 patent/US9689033B2/en active Active
- 2014-11-26 AU AU2014354726A patent/AU2014354726B2/en active Active
- 2014-11-26 FI FIEP19161148.2T patent/FI3556869T3/fi active
- 2014-11-26 CN CN202110859489.8A patent/CN113528632A/zh active Pending
- 2014-11-26 EP EP14830903.2A patent/EP3074534B1/en active Active
- 2014-11-26 DK DK14830903.2T patent/DK3074534T3/da active
- 2014-11-26 CN CN201480064725.5A patent/CN105934522B/zh active Active
- 2014-11-26 EP EP23188555.9A patent/EP4282983A3/en active Pending
- 2014-11-26 WO PCT/US2014/067582 patent/WO2015081178A1/en not_active Ceased
- 2014-11-26 WO PCT/US2014/067639 patent/WO2015081211A2/en not_active Ceased
- 2014-11-26 ES ES19161148T patent/ES2958715T3/es active Active
- 2014-11-26 SI SI201431264T patent/SI3074534T1/sl unknown
- 2014-11-26 ES ES14830903T patent/ES2735015T3/es active Active
- 2014-11-26 CA CA2926871A patent/CA2926871C/en active Active
- 2014-11-26 LT LTEP14830903.2T patent/LT3074534T/lt unknown
- 2014-11-26 JP JP2016521718A patent/JP6800749B2/ja active Active
- 2014-11-26 DK DK19161148.2T patent/DK3556869T3/da active
- 2014-11-26 CA CA3157586A patent/CA3157586C/en active Active
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2017
- 2017-05-26 US US15/606,354 patent/US10364462B2/en active Active
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2019
- 2019-06-12 US US16/439,022 patent/US11041196B2/en active Active
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2020
- 2020-04-14 AU AU2020202489A patent/AU2020202489B2/en active Active
- 2020-11-25 JP JP2020195453A patent/JP7349972B2/ja active Active
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2021
- 2021-05-25 US US17/329,482 patent/US11879155B2/en active Active
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2022
- 2022-09-16 AU AU2022231786A patent/AU2022231786B2/en active Active
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2023
- 2023-05-30 JP JP2023088480A patent/JP2023116553A/ja active Pending
- 2023-12-08 US US18/533,863 patent/US20240167085A1/en active Pending
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2025
- 2025-02-05 JP JP2025017268A patent/JP2025072503A/ja active Pending
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