FI3556869T3 - Koostumuksia ja menetelmiä polynukleotidien sekvensointiin - Google Patents
Koostumuksia ja menetelmiä polynukleotidien sekvensointiin Download PDFInfo
- Publication number
- FI3556869T3 FI3556869T3 FIEP19161148.2T FI19161148T FI3556869T3 FI 3556869 T3 FI3556869 T3 FI 3556869T3 FI 19161148 T FI19161148 T FI 19161148T FI 3556869 T3 FI3556869 T3 FI 3556869T3
- Authority
- FI
- Finland
- Prior art keywords
- pore
- target polynucleotide
- helicase
- polynucleotide
- concentration
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361909316P | 2013-11-26 | 2013-11-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3556869T3 true FI3556869T3 (fi) | 2023-09-28 |
Family
ID=52424089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP19161148.2T FI3556869T3 (fi) | 2013-11-26 | 2014-11-26 | Koostumuksia ja menetelmiä polynukleotidien sekvensointiin |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US9689033B2 (https=) |
| EP (3) | EP4282983A3 (https=) |
| JP (4) | JP6800749B2 (https=) |
| CN (2) | CN105934522B (https=) |
| AU (3) | AU2014354726B2 (https=) |
| CA (2) | CA3157586C (https=) |
| DK (2) | DK3556869T3 (https=) |
| ES (2) | ES2958715T3 (https=) |
| FI (1) | FI3556869T3 (https=) |
| LT (1) | LT3074534T (https=) |
| SI (1) | SI3074534T1 (https=) |
| WO (2) | WO2015081211A2 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0905140D0 (en) | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| JP6457811B2 (ja) * | 2011-09-23 | 2019-01-23 | オックスフォード ナノポール テクノロジーズ リミテッド | ポリマー単位を含むポリマーの解析 |
| CN104321441B (zh) | 2012-02-16 | 2016-10-19 | 牛津楠路珀尔科技有限公司 | 聚合物的测量的分析 |
| KR102083695B1 (ko) | 2012-04-10 | 2020-03-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 리세닌 기공 |
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
| SI3074534T1 (sl) * | 2013-11-26 | 2019-08-30 | Illumina, Inc. | Postopki določanja zaporedja polinukleotidov |
| CN111534504B (zh) | 2014-01-22 | 2024-06-21 | 牛津纳米孔科技公开有限公司 | 将一个或多个多核苷酸结合蛋白连接到靶多核苷酸的方法 |
| US10359395B2 (en) * | 2014-02-19 | 2019-07-23 | University Of Washington | Nanopore-based analysis of protein characteristics |
| EP3137490B1 (en) | 2014-05-02 | 2021-01-27 | Oxford Nanopore Technologies Limited | Mutant pores |
| CA2959220A1 (en) | 2014-09-01 | 2016-03-10 | Vib Vzw | Mutant csgg pores |
| EP4397972A3 (en) | 2014-10-16 | 2024-10-09 | Oxford Nanopore Technologies PLC | Alignment mapping estimation |
| WO2017027518A1 (en) * | 2015-08-10 | 2017-02-16 | Stratos Genomics, Inc. | Single molecule nucleic acid sequencing with molecular sensor complexes |
| JP2018533010A (ja) * | 2015-10-21 | 2018-11-08 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ナノポアベースのｄｎａ配列決定のための脂質二重層形成を支援するための撥水性層としてのフルオロポリマーの使用 |
| CN116200476A (zh) | 2016-03-02 | 2023-06-02 | 牛津纳米孔科技公开有限公司 | 靶分析物测定方法、突变CsgG单体及其构筑体、及聚核苷酸和寡聚孔 |
| EP4397970A3 (en) | 2016-04-06 | 2024-10-09 | Oxford Nanopore Technologies PLC | Mutant pore |
| EP3442697A4 (en) | 2016-04-14 | 2020-03-18 | Lockheed Martin Corporation | SELECTIVE INTERFACE REDUCTION OF GRAPH DEFECTS |
| WO2017223515A1 (en) * | 2016-06-23 | 2017-12-28 | F. Hoffman-La Roche Ag | Formation and calibration of nanopore sequencing cells |
| WO2018029108A1 (en) | 2016-08-08 | 2018-02-15 | F. Hoffmann-La Roche Ag | Basecalling for stochastic sequencing processes |
| EP3529380B1 (en) | 2016-10-19 | 2022-06-29 | Illumina, Inc. | Methods for chemical ligation of nucleic acids |
| GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
| CN117106038B (zh) | 2017-06-30 | 2025-12-09 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
| WO2019055867A1 (en) * | 2017-09-15 | 2019-03-21 | Illumina, Inc. | SEQUENCE DETECTION SYSTEM |
| EP3682023B1 (en) * | 2017-09-15 | 2026-01-28 | Illumina, Inc. | Tuning and calibration features of a sequence-detection system |
| US10310959B2 (en) | 2017-11-07 | 2019-06-04 | Bank Of America Corporation | Pre-deployment validation system using intelligent databases |
| CN112292461B (zh) * | 2018-06-21 | 2024-05-17 | 豪夫迈·罗氏有限公司 | 用于测序的隧穿结 |
| US20190390268A1 (en) * | 2018-06-26 | 2019-12-26 | Electronic Biosciences, Inc. | Controlled nanopore translocation utilizing extremophilic replication proteins |
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| JP2020031557A (ja) * | 2018-08-28 | 2020-03-05 | 株式会社日立ハイテクノロジーズ | 生体分子分析装置 |
| WO2020084705A1 (ja) * | 2018-10-24 | 2020-04-30 | 株式会社日立ハイテク | 生体ポリマ分析デバイス及びそれを用いた分析装置、並びに分析方法 |
| GB201907244D0 (en) * | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| WO2021056598A1 (zh) | 2019-09-29 | 2021-04-01 | 北京齐碳科技有限公司 | 一种Mmup单体变体及其应用 |
| US20220412948A1 (en) * | 2019-11-19 | 2022-12-29 | Rijksuniversiteit Groningen | Artificial nanopores and uses and methods relating thereto |
| NL2024579B1 (en) * | 2019-12-24 | 2021-09-06 | Univ Delft Tech | Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes |
| CN114807317A (zh) * | 2021-01-22 | 2022-07-29 | 上海羿鸣生物科技有限公司 | 一种优化的dna线性扩增方法及试剂盒 |
| GB202107192D0 (en) * | 2021-05-19 | 2021-06-30 | Oxford Nanopore Tech Ltd | Method |
| CN113322180B (zh) * | 2021-05-31 | 2022-07-15 | 中国科学院物理研究所 | 基于纳米孔测序的力谱分析方法和分析装置 |
| US20230298693A1 (en) * | 2022-02-28 | 2023-09-21 | Rajant Health Incorporated | Alignment-free variant calling |
| KR20250116014A (ko) | 2022-10-28 | 2025-07-31 | 리엑스유니버시테이트 그로닝겐 | 나노기공-기반 단백질 분석 |
| EP4698646A2 (en) * | 2023-04-21 | 2026-02-25 | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 1475 North Scottsdale Road | Novel transmembrane sensors and method of characterization for lysis-free detection of intracellular targets |
| WO2026073207A1 (en) | 2024-09-30 | 2026-04-02 | Illumina, Inc. | Affinity-binder-based assay compositions and methods |
| CN119639558B (zh) * | 2024-12-13 | 2025-09-26 | 杭州海兰时生物科技有限责任公司 | 一种用于单细胞测序的液滴融合系统 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
| US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
| US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
| US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
| US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
| US5508179A (en) | 1994-03-18 | 1996-04-16 | Bio-Rad Laboratories, Inc. | Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions |
| US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
| EP2383776B1 (en) | 1999-06-22 | 2015-02-25 | President and Fellows of Harvard College | Solid state nanopore device for evaluating biopolymers |
| US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| DK1259643T3 (da) | 2000-02-07 | 2009-02-23 | Illumina Inc | Fremgangsmåde til detektion af nukleinsyre ved anvendelse af universel priming |
| US6913884B2 (en) | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
| GB0505971D0 (en) | 2005-03-23 | 2005-04-27 | Isis Innovation | Delivery of molecules to a lipid bilayer |
| US20110121840A1 (en) | 2007-02-20 | 2011-05-26 | Gurdial Singh Sanghera | Lipid Bilayer Sensor System |
| US20110229877A1 (en) * | 2008-07-07 | 2011-09-22 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
| CA2774710C (en) | 2008-09-22 | 2016-08-02 | University Of Washington | Msp nanopores and related methods |
| GB0905140D0 (en) * | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| WO2012033524A2 (en) * | 2010-09-07 | 2012-03-15 | The Regents Of The University Of California | Control of dna movement in a nanopore at one nucleotide precision by a processive enzyme |
| KR102023754B1 (ko) | 2011-07-27 | 2019-09-20 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 생체분자 특성규명용 나노포어 센서 |
| CN104039979B (zh) * | 2011-10-21 | 2016-08-24 | 牛津纳米孔技术公司 | 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法 |
| AU2012360244B2 (en) | 2011-12-29 | 2018-08-23 | Oxford Nanopore Technologies Limited | Enzyme method |
| US9617591B2 (en) | 2011-12-29 | 2017-04-11 | Oxford Nanopore Technologies Ltd. | Method for characterising a polynucleotide by using a XPD helicase |
| JP5809572B2 (ja) | 2012-01-30 | 2015-11-11 | ルネサスエレクトロニクス株式会社 | 半導体装置 |
| KR102083695B1 (ko) | 2012-04-10 | 2020-03-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 리세닌 기공 |
| GB2559073A (en) * | 2012-06-08 | 2018-07-25 | Pacific Biosciences California Inc | Modified base detection with nanopore sequencing |
| CA2879261C (en) * | 2012-07-19 | 2022-12-06 | Oxford Nanopore Technologies Limited | Modified helicases |
| SI3074534T1 (sl) * | 2013-11-26 | 2019-08-30 | Illumina, Inc. | Postopki določanja zaporedja polinukleotidov |
-
2014
- 2014-11-26 SI SI201431264T patent/SI3074534T1/sl unknown
- 2014-11-26 ES ES19161148T patent/ES2958715T3/es active Active
- 2014-11-26 CN CN201480064725.5A patent/CN105934522B/zh active Active
- 2014-11-26 CA CA3157586A patent/CA3157586C/en active Active
- 2014-11-26 DK DK19161148.2T patent/DK3556869T3/da active
- 2014-11-26 JP JP2016521718A patent/JP6800749B2/ja active Active
- 2014-11-26 CN CN202110859489.8A patent/CN113528632A/zh active Pending
- 2014-11-26 WO PCT/US2014/067639 patent/WO2015081211A2/en not_active Ceased
- 2014-11-26 EP EP23188555.9A patent/EP4282983A3/en active Pending
- 2014-11-26 ES ES14830903T patent/ES2735015T3/es active Active
- 2014-11-26 AU AU2014354726A patent/AU2014354726B2/en active Active
- 2014-11-26 CA CA2926871A patent/CA2926871C/en active Active
- 2014-11-26 WO PCT/US2014/067582 patent/WO2015081178A1/en not_active Ceased
- 2014-11-26 FI FIEP19161148.2T patent/FI3556869T3/fi active
- 2014-11-26 DK DK14830903.2T patent/DK3074534T3/da active
- 2014-11-26 US US14/554,741 patent/US9689033B2/en active Active
- 2014-11-26 EP EP14830903.2A patent/EP3074534B1/en active Active
- 2014-11-26 LT LTEP14830903.2T patent/LT3074534T/lt unknown
- 2014-11-26 EP EP19161148.2A patent/EP3556869B1/en active Active
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2017
- 2017-05-26 US US15/606,354 patent/US10364462B2/en active Active
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2019
- 2019-06-12 US US16/439,022 patent/US11041196B2/en active Active
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2020
- 2020-04-14 AU AU2020202489A patent/AU2020202489B2/en active Active
- 2020-11-25 JP JP2020195453A patent/JP7349972B2/ja active Active
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2021
- 2021-05-25 US US17/329,482 patent/US11879155B2/en active Active
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2022
- 2022-09-16 AU AU2022231786A patent/AU2022231786B2/en active Active
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2023
- 2023-05-30 JP JP2023088480A patent/JP2023116553A/ja active Pending
- 2023-12-08 US US18/533,863 patent/US20240167085A1/en active Pending
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2025
- 2025-02-05 JP JP2025017268A patent/JP2025072503A/ja active Pending
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