JP2017502013A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017502013A5 JP2017502013A5 JP2016540553A JP2016540553A JP2017502013A5 JP 2017502013 A5 JP2017502013 A5 JP 2017502013A5 JP 2016540553 A JP2016540553 A JP 2016540553A JP 2016540553 A JP2016540553 A JP 2016540553A JP 2017502013 A5 JP2017502013 A5 JP 2017502013A5
- Authority
- JP
- Japan
- Prior art keywords
- cas number
- inhibitor
- delta
- cancer
- intellikine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919597P | 2013-12-20 | 2013-12-20 | |
| US61/919,597 | 2013-12-20 | ||
| PCT/US2014/071747 WO2015095840A1 (en) | 2013-12-20 | 2014-12-19 | Cancer treatments using combinations of cdk and erk inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017502013A JP2017502013A (ja) | 2017-01-19 |
| JP2017502013A5 true JP2017502013A5 (enExample) | 2018-02-01 |
| JP6678584B2 JP6678584B2 (ja) | 2020-04-22 |
Family
ID=53403797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540553A Active JP6678584B2 (ja) | 2013-12-20 | 2014-12-19 | Ｃｄｋ阻害剤およびｅｒｋ阻害剤の組み合わせを使用するがん処置 |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US11013743B2 (enExample) |
| EP (2) | EP4512480A3 (enExample) |
| JP (1) | JP6678584B2 (enExample) |
| AU (1) | AU2014368927B2 (enExample) |
| ES (1) | ES3033810T3 (enExample) |
| WO (1) | WO2015095840A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0906473A8 (pt) | 2008-01-04 | 2016-02-10 | Intellikine Inc | Certas entidades químicas, composições e métodos |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| EP3238722B1 (en) | 2011-01-10 | 2019-03-13 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinones |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| RU2702908C2 (ru) | 2012-11-01 | 2019-10-14 | Инфинити Фармасьютикалз, Инк. | Лечение злокачественных опухолей с использованием модуляторов изоформ pi3-киназы |
| WO2015160975A2 (en) | 2014-04-16 | 2015-10-22 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2017021177A1 (en) * | 2015-08-04 | 2017-02-09 | Universitat De Barcelona | Pharmaceutical combinations for use in the treatment of cancer |
| WO2017037574A1 (en) * | 2015-08-28 | 2017-03-09 | Novartis Ag | Combinations of the cdk4/6 inhibitor lee011 and the mek1/2 inhibitor trametinib, optionally further comprising the pi3k inhibitor byl719 to treat cancer |
| RU2749025C2 (ru) * | 2016-03-24 | 2021-06-03 | Трагара Фармасьютикалз, Инк. | Лечение рака при помощи tg02 |
| GB201605126D0 (en) * | 2016-03-24 | 2016-05-11 | Univ Nottingham | Inhibitors and their uses |
| EP3474856B1 (en) | 2016-06-24 | 2022-09-14 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| WO2018081204A1 (en) * | 2016-10-26 | 2018-05-03 | Li George Y | DEUTERATED N-(5-((4-ETHYLPIPERAZIN-1-YL)METHYL) PYRIDIN-2-YL)-5-FLUORO-4-(4-FLUORO-1-ISOPROPYL-2-METHYL-1H-BENZO[d]IMIDAZOL-6-YL)PYRIMIDIN-2-AMINE |
| WO2018213302A1 (en) * | 2017-05-16 | 2018-11-22 | Biomed Valley Discoveries, Inc. | Compositions and methods for treating cancer with atypical braf mutations |
| WO2018218633A1 (en) * | 2017-06-02 | 2018-12-06 | Beijing Percans Oncology Co. Ltd. | Combination therapies for treating cancers |
| JP2019116429A (ja) * | 2017-12-26 | 2019-07-18 | 国立大学法人名古屋大学 | 抗ウイルス薬 |
| WO2019136451A1 (en) | 2018-01-08 | 2019-07-11 | G1 Therapeutics, Inc. | G1t38 superior dosage regimes |
| CN111867586A (zh) * | 2018-03-13 | 2020-10-30 | 得克萨斯州大学系统董事会 | 用于治疗具有egfr激活突变的癌症的方法 |
| WO2019195959A1 (en) | 2018-04-08 | 2019-10-17 | Cothera Biosciences, Inc. | Combination therapy for cancers with braf mutation |
| WO2019199883A1 (en) * | 2018-04-09 | 2019-10-17 | G1 Therapeutics, Inc. | Treatment of cancers having driving oncogenic mutations |
| WO2020036852A1 (en) | 2018-08-13 | 2020-02-20 | Beijing Percans Oncology Co. Ltd. | Biomarkers for cancer therapy |
| US11066404B2 (en) | 2018-10-11 | 2021-07-20 | Incyte Corporation | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors |
| WO2020168197A1 (en) | 2019-02-15 | 2020-08-20 | Incyte Corporation | Pyrrolo[2,3-d]pyrimidinone compounds as cdk2 inhibitors |
| EA202192260A1 (ru) * | 2019-02-15 | 2021-12-17 | Инсайт Корпорейшн | Биомаркеры циклин-зависимой киназы 2 и их применение |
| TW202100520A (zh) | 2019-03-05 | 2021-01-01 | 美商英塞特公司 | 作為cdk2 抑制劑之吡唑基嘧啶基胺化合物 |
| US11919904B2 (en) | 2019-03-29 | 2024-03-05 | Incyte Corporation | Sulfonylamide compounds as CDK2 inhibitors |
| WO2020223558A1 (en) | 2019-05-01 | 2020-11-05 | Incyte Corporation | Tricyclic amine compounds as cdk2 inhibitors |
| WO2020223469A1 (en) | 2019-05-01 | 2020-11-05 | Incyte Corporation | N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer |
| WO2021030537A1 (en) | 2019-08-14 | 2021-02-18 | Incyte Corporation | Imidazolyl pyrimidinylamine compounds as cdk2 inhibitors |
| CR20220170A (es) | 2019-10-11 | 2022-10-10 | Incyte Corp | Aminas bicíclicas como inhibidoras de la cdk2 |
| US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
| US11976073B2 (en) | 2021-12-10 | 2024-05-07 | Incyte Corporation | Bicyclic amines as CDK2 inhibitors |
| CN117224679B (zh) * | 2023-07-21 | 2026-03-24 | 上海交通大学医学院附属瑞金医院 | 选择性cdk9调节剂在制备肾上腺皮质癌药物中的应用 |
| CN117224545A (zh) * | 2023-09-26 | 2023-12-15 | 中国人民解放军陆军军医大学第二附属医院 | Aminopurvalanol A在制备治疗肺腺癌的药物中的应用 |
| WO2025111447A1 (en) * | 2023-11-21 | 2025-05-30 | Florida Atlantic University Board Of Trustees | Treatment of cancer with drug combinations |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08507926A (ja) | 1993-03-19 | 1996-08-27 | シーケノム・インコーポレーテツド | エキソヌクレアーゼ分解を介した質量分析法によるｄｎａ配列決定 |
| US6140053A (en) | 1996-11-06 | 2000-10-31 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
| US7439016B1 (en) | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| NZ534069A (en) * | 2002-01-22 | 2007-03-30 | Warner Lambert Co | 2-(Pyridin-2-ylamino)-pyrido[2,3-d]pyrimidin-7-ones to be used to treat neurodegenerative disorders, viruses and cancer |
| US7119200B2 (en) * | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
| GB0320059D0 (en) | 2003-08-27 | 2003-10-01 | Solexa Ltd | A method of sequencing |
| ES2897422T3 (es) | 2004-05-14 | 2022-03-01 | Vertex Pharma | Compuestos pirroles como inhibidores de proteínas cinasas ERK y composiciones farmacéuticas que contienen esos compuestos |
| US7582623B2 (en) | 2004-05-20 | 2009-09-01 | The Regents Of The University Of California | Photoactive metal nitrosyls for blood pressure regulation and cancer therapy |
| US20060228721A1 (en) | 2005-04-12 | 2006-10-12 | Leamon John H | Methods for determining sequence variants using ultra-deep sequencing |
| AR068046A1 (es) * | 2007-06-05 | 2009-11-04 | Schering Corp | Derivados policiclicos de indazol y su uso como inhibidores de erk para el tratamiento del cancer |
| AU2009284098B2 (en) * | 2008-08-22 | 2012-03-29 | Astex Therapeutics Ltd. | Pyrrolopyrimidine compounds as CDK inhibitors |
| TWI419974B (zh) | 2008-10-27 | 2013-12-21 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
| KR20120046018A (ko) | 2010-10-04 | 2012-05-09 | 삼성테크윈 주식회사 | 단일 뉴클레오티드 다형성의 실시간 ｐｃｒ 검출 |
| WO2012125848A2 (en) | 2011-03-16 | 2012-09-20 | Baylor College Of Medicine | A method for comprehensive sequence analysis using deep sequencing technology |
-
2014
- 2014-12-19 US US15/105,924 patent/US11013743B2/en active Active
- 2014-12-19 EP EP24217401.9A patent/EP4512480A3/en active Pending
- 2014-12-19 ES ES14872163T patent/ES3033810T3/es active Active
- 2014-12-19 EP EP14872163.2A patent/EP3082423B1/en active Active
- 2014-12-19 JP JP2016540553A patent/JP6678584B2/ja active Active
- 2014-12-19 WO PCT/US2014/071747 patent/WO2015095840A1/en not_active Ceased
- 2014-12-19 AU AU2014368927A patent/AU2014368927B2/en active Active
-
2020
- 2020-04-23 US US16/856,849 patent/US11135225B2/en active Active
-
2021
- 2021-08-30 US US17/460,743 patent/US11679112B2/en active Active
-
2023
- 2023-05-01 US US18/310,034 patent/US12076324B2/en active Active
-
2024
- 2024-07-29 US US18/787,389 patent/US20240374604A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017502017A5 (enExample) | ||
| JP2017502016A5 (enExample) | ||
| JP2017500320A5 (enExample) | ||
| RU2016129287A (ru) | Лечение злокачественных опухолей с применением комбинаций ингибиторов erk и raf | |
| Nonnenmacher et al. | RIST: A potent new combination therapy for glioblastoma | |
| Linch et al. | Systemic treatment of soft-tissue sarcoma—gold standard and novel therapies | |
| Garcia del Muro et al. | A phase II trial of temozolomide as a 6‐week, continuous, oral schedule in patients with advanced soft tissue sarcoma: a study by the Spanish Group for Research on Sarcomas | |
| JP2017502014A5 (enExample) | ||
| Gutteridge et al. | Plk1 inhibitors in cancer therapy: from laboratory to clinics | |
| RU2717570C2 (ru) | Синергистические комбинации ауристана | |
| O’Sullivan | Overcoming endocrine resistance in hormone-receptor positive advanced breast cancer-the emerging role of CDK4/6 inhibitors | |
| Bailón-Moscoso et al. | Development of anticancer drugs based on the hallmarks of tumor cells | |
| EP3442529B1 (en) | Combination therapy with notch and cdk4/6 inhibitors for the treatment of lung cancer | |
| Efferth et al. | Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature | |
| Kirstein et al. | Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3‐kinase inhibitor BEZ235 and the PI3‐kinase inhibitor BKM120 in hepatocellular carcinoma | |
| EA201200560A1 (ru) | Специфическая терапия, использующая интегриновые лиганды для лечения рака | |
| JP2015526410A5 (enExample) | ||
| RU2017102319A (ru) | Прерывистое введение ингибитора mdm2 | |
| EA200900912A1 (ru) | Специфическая терапия и лекарственное средство на основе интегриновых лигандов для лечения рака | |
| MX2014002471A (es) | Combinaciones sinergicas de los inhibidores de p13k y mek. | |
| BR112014027010A2 (pt) | uso de laquinimod de alta dose para tratamento de esclerose múltipla | |
| EP4520398A3 (en) | Treatment of prostate cancer | |
| CA2939464A1 (en) | Use of anti-ccr5 antibodies in graft versus host disease | |
| Hicks et al. | Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo | |
| AU2012257833A1 (en) | Method for treatment of solid malignancies including advanced or metastatic solid malignancies |