JP2017501211A5 - - Google Patents
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- Publication number
- JP2017501211A5 JP2017501211A5 JP2016552481A JP2016552481A JP2017501211A5 JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5 JP 2016552481 A JP2016552481 A JP 2016552481A JP 2016552481 A JP2016552481 A JP 2016552481A JP 2017501211 A5 JP2017501211 A5 JP 2017501211A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- chain variable
- variable region
- antibody
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361900942P | 2013-11-06 | 2013-11-06 | |
| US61/900,942 | 2013-11-06 | ||
| US201462054324P | 2014-09-23 | 2014-09-23 | |
| US62/054,324 | 2014-09-23 | ||
| US201462064380P | 2014-10-15 | 2014-10-15 | |
| US62/064,380 | 2014-10-15 | ||
| PCT/US2014/064327 WO2015069880A1 (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Division JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017501211A JP2017501211A (ja) | 2017-01-12 |
| JP2017501211A5 true JP2017501211A5 (OSRAM) | 2017-11-24 |
Family
ID=53042071
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552481A Pending JP2017501211A (ja) | 2013-11-06 | 2014-11-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019212462A Pending JP2020048569A (ja) | 2013-11-06 | 2019-11-25 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2022003920A Active JP7277623B2 (ja) | 2013-11-06 | 2022-01-13 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
| JP2023000938A Pending JP2023052239A (ja) | 2013-11-06 | 2023-01-06 | 生体試料中で改善された性能を有するｉｇｆｂｐ７のためのアッセイ |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9822172B2 (OSRAM) |
| EP (2) | EP3066221A4 (OSRAM) |
| JP (4) | JP2017501211A (OSRAM) |
| KR (1) | KR102404285B1 (OSRAM) |
| CN (1) | CN105793439B (OSRAM) |
| AU (1) | AU2014346695B2 (OSRAM) |
| BR (1) | BR112016010106A2 (OSRAM) |
| CA (2) | CA2929547C (OSRAM) |
| EA (1) | EA201690731A1 (OSRAM) |
| HK (1) | HK1221490A1 (OSRAM) |
| MX (1) | MX375701B (OSRAM) |
| WO (1) | WO2015069880A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ628843A (en) | 2008-10-21 | 2016-02-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| WO2011162821A1 (en) | 2010-06-23 | 2011-12-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2013086359A1 (en) | 2011-12-08 | 2013-06-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA3158996C (en) | 2013-01-17 | 2024-06-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN105917229B (zh) | 2013-12-03 | 2019-04-26 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| WO2016164854A1 (en) | 2015-04-09 | 2016-10-13 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN108139409B (zh) * | 2015-10-08 | 2020-07-24 | 豪夫迈·罗氏有限公司 | 当在外科手术之前测量时用于预测aki的风险的igfbp7 |
| AU2017277305A1 (en) | 2016-06-06 | 2018-12-20 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN110709103B (zh) | 2017-04-05 | 2024-02-02 | 机敏医药股份有限公司 | 用于生物学样品中具有改善的性能的timp2的测定法 |
| CN112384807A (zh) | 2018-05-24 | 2021-02-19 | 雷尼布斯治疗公司 | 治疗有风险患有肾损伤和肾衰竭的患者的方法 |
| WO2020234482A1 (en) * | 2019-05-21 | 2020-11-26 | Universität Zürich | MAPKi RESISTANCE SIGNATURES |
| KR102533791B1 (ko) * | 2022-09-15 | 2023-05-18 | 경북대학교 산학협력단 | 비색법 신호형질 복합체, 이를 이용하는 신장질환 진단용 키트 및 진단법 |
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| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5939272A (en) | 1989-01-10 | 1999-08-17 | Biosite Diagnostics Incorporated | Non-competitive threshold ligand-receptor assays |
| US5028535A (en) | 1989-01-10 | 1991-07-02 | Biosite Diagnostics, Inc. | Threshold ligand-receptor assay |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| US5922615A (en) | 1990-03-12 | 1999-07-13 | Biosite Diagnostics Incorporated | Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network |
| US5166051A (en) | 1990-08-08 | 1992-11-24 | Genesis Labs, Inc. | Membranes, membrane overlays for exclusion of erythrocytes, and method for immunoassay of whole blood analytes |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
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| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| WO1992005282A1 (en) | 1990-09-14 | 1992-04-02 | Biosite Diagnostics, Inc. | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| GB9109645D0 (en) * | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| ATE177841T1 (de) | 1991-04-10 | 1999-04-15 | Biosite Diagnostics Inc | ''crosstalk''- oder übersprech-inhibitoren und ihre verwendung |
| EP0579767B1 (en) | 1991-04-11 | 2000-08-23 | Biosite Diagnostics Inc. | Novel conjugates and assays for simultaneous detection of multiple ligands |
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| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
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| US5824799A (en) | 1993-09-24 | 1998-10-20 | Biosite Diagnostics Incorporated | Hybrid phthalocyanine derivatives and their uses |
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| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
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| JP2008541017A (ja) | 2005-04-29 | 2008-11-20 | ベックマン コールター インコーポレイテッド | 側方流動蛍光免疫測定法 |
| WO2007008547A2 (en) | 2005-07-08 | 2007-01-18 | Biogen Idec Ma Inc. | Sp35 antibodies and uses thereof |
| PL2115477T3 (pl) * | 2007-01-25 | 2015-12-31 | Hoffmann La Roche | Zastosowanie IGFBP-7 do oceny niewydolności serca |
| CA2740134C (en) * | 2008-10-14 | 2021-10-26 | National Research Council Of Canada | Formulations targeting igfbp7 for diagnosis and therapy of cancer |
| JP2012525441A (ja) * | 2009-05-01 | 2012-10-22 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリンおよびこの使用 |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| DK2666872T3 (en) | 2010-02-05 | 2016-07-25 | Astute Medical Inc | Methods and compositions for the diagnosis and prognosis of renal injury and renal insufficiency |
| BR112013004776A2 (pt) * | 2010-08-27 | 2017-09-19 | Stem Centrx Inc | moduladores de proteína notum e métodos de uso |
| HK1201279A1 (en) * | 2011-11-03 | 2015-08-28 | Tolera Therapeutics Inc. | Antibody and methods for selective inhibition of t-cell responses |
-
2014
- 2014-11-06 MX MX2016005834A patent/MX375701B/es active IP Right Grant
- 2014-11-06 WO PCT/US2014/064327 patent/WO2015069880A1/en not_active Ceased
- 2014-11-06 HK HK16109610.3A patent/HK1221490A1/zh unknown
- 2014-11-06 EA EA201690731A patent/EA201690731A1/ru unknown
- 2014-11-06 BR BR112016010106A patent/BR112016010106A2/pt not_active Application Discontinuation
- 2014-11-06 CA CA2929547A patent/CA2929547C/en active Active
- 2014-11-06 EP EP14860878.9A patent/EP3066221A4/en not_active Withdrawn
- 2014-11-06 CN CN201480066318.8A patent/CN105793439B/zh active Active
- 2014-11-06 EP EP19158290.7A patent/EP3556863B1/en active Active
- 2014-11-06 KR KR1020167014700A patent/KR102404285B1/ko active Active
- 2014-11-06 US US15/035,205 patent/US9822172B2/en active Active
- 2014-11-06 JP JP2016552481A patent/JP2017501211A/ja active Pending
- 2014-11-06 CA CA3185700A patent/CA3185700A1/en active Pending
- 2014-11-06 AU AU2014346695A patent/AU2014346695B2/en active Active
-
2017
- 2017-11-20 US US15/818,669 patent/US10562961B2/en active Active
-
2019
- 2019-11-25 JP JP2019212462A patent/JP2020048569A/ja active Pending
-
2020
- 2020-01-17 US US16/745,781 patent/US20200247879A1/en not_active Abandoned
-
2022
- 2022-01-13 JP JP2022003920A patent/JP7277623B2/ja active Active
-
2023
- 2023-01-06 JP JP2023000938A patent/JP2023052239A/ja active Pending
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