CA3185700A1 - Assays for igfbp7 having improved performance in biological samples - Google Patents
Assays for igfbp7 having improved performance in biological samplesInfo
- Publication number
- CA3185700A1 CA3185700A1 CA3185700A CA3185700A CA3185700A1 CA 3185700 A1 CA3185700 A1 CA 3185700A1 CA 3185700 A CA3185700 A CA 3185700A CA 3185700 A CA3185700 A CA 3185700A CA 3185700 A1 CA3185700 A1 CA 3185700A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- igfbp7
- human
- antibodies
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- XETCRXVKJHBPMK-MJSODCSWSA-N trehalose 6,6'-dimycolate Chemical compound C([C@@H]1[C@H]([C@H](O)[C@@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](COC(=O)C(CCCCCCCCCCC3C(C3)CCCCCCCCCCCCCCCCCC)C(O)CCCCCCCCCCCCCCCCCCCCCCCCC)O2)O)O1)O)OC(=O)C(C(O)CCCCCCCCCCCCCCCCCCCCCCCCC)CCCCCCCCCCC1CC1CCCCCCCCCCCCCCCCCC XETCRXVKJHBPMK-MJSODCSWSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 150000003673 urethanes Chemical class 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4745—Insulin-like growth factor binding protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361900942P | 2013-11-06 | 2013-11-06 | |
| US61/900,942 | 2013-11-06 | ||
| US201462054324P | 2014-09-23 | 2014-09-23 | |
| US62/054,324 | 2014-09-23 | ||
| US201462064380P | 2014-10-15 | 2014-10-15 | |
| US62/064,380 | 2014-10-15 | ||
| CA2929547A CA2929547C (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2929547A Division CA2929547C (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3185700A1 true CA3185700A1 (en) | 2015-05-14 |
Family
ID=53042071
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3185700A Pending CA3185700A1 (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
| CA2929547A Active CA2929547C (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2929547A Active CA2929547C (en) | 2013-11-06 | 2014-11-06 | Assays for igfbp7 having improved performance in biological samples |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US9822172B2 (OSRAM) |
| EP (2) | EP3556863B1 (OSRAM) |
| JP (4) | JP2017501211A (OSRAM) |
| KR (1) | KR102404285B1 (OSRAM) |
| CN (1) | CN105793439B (OSRAM) |
| AU (1) | AU2014346695B2 (OSRAM) |
| BR (1) | BR112016010106A2 (OSRAM) |
| CA (2) | CA3185700A1 (OSRAM) |
| EA (1) | EA201690731A1 (OSRAM) |
| HK (1) | HK1221490A1 (OSRAM) |
| MX (1) | MX375701B (OSRAM) |
| WO (1) | WO2015069880A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010048346A1 (en) | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| ES2818138T3 (es) | 2009-12-20 | 2021-04-09 | Astute Medical Inc | Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal |
| EP2585827A4 (en) | 2010-06-23 | 2013-12-04 | Astute Medical Inc | METHOD AND COMPOSITIONS FOR DIAGNOSIS AND FORECASTING kidney injury and kidney insufficiency |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| JP6681195B2 (ja) | 2013-01-17 | 2020-04-15 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| JP2016540759A (ja) | 2013-12-03 | 2016-12-28 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
| US11243202B2 (en) | 2015-04-09 | 2022-02-08 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN108139409B (zh) * | 2015-10-08 | 2020-07-24 | 豪夫迈·罗氏有限公司 | 当在外科手术之前测量时用于预测aki的风险的igfbp7 |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| CN110431422A (zh) | 2017-02-06 | 2019-11-08 | 机敏医药股份有限公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| US11718682B2 (en) | 2017-04-05 | 2023-08-08 | Astute Medical, Inc. | Assays for TIMP2 having improved performance in biological samples |
| CN112384807A (zh) | 2018-05-24 | 2021-02-19 | 雷尼布斯治疗公司 | 治疗有风险患有肾损伤和肾衰竭的患者的方法 |
| WO2020234482A1 (en) * | 2019-05-21 | 2020-11-26 | Universität Zürich | MAPKi RESISTANCE SIGNATURES |
| KR102533791B1 (ko) * | 2022-09-15 | 2023-05-18 | 경북대학교 산학협력단 | 비색법 신호형질 복합체, 이를 이용하는 신장질환 진단용 키트 및 진단법 |
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| DE3029579C2 (de) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
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| RU2013113638A (ru) * | 2010-08-27 | 2014-10-10 | Стем Сентркс, Инк. | МОДУЛЯТОРЫ БЕЛКА Notum И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| CN104870011A (zh) * | 2011-11-03 | 2015-08-26 | 托莱拉医疗股份有限公司 | 选择性抑制t细胞应答的抗体和方法 |
-
2014
- 2014-11-06 WO PCT/US2014/064327 patent/WO2015069880A1/en not_active Ceased
- 2014-11-06 CA CA3185700A patent/CA3185700A1/en active Pending
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- 2014-11-06 EP EP19158290.7A patent/EP3556863B1/en active Active
- 2014-11-06 BR BR112016010106A patent/BR112016010106A2/pt not_active Application Discontinuation
- 2014-11-06 HK HK16109610.3A patent/HK1221490A1/zh unknown
- 2014-11-06 KR KR1020167014700A patent/KR102404285B1/ko active Active
- 2014-11-06 EP EP14860878.9A patent/EP3066221A4/en not_active Withdrawn
- 2014-11-06 MX MX2016005834A patent/MX375701B/es active IP Right Grant
- 2014-11-06 JP JP2016552481A patent/JP2017501211A/ja active Pending
- 2014-11-06 EA EA201690731A patent/EA201690731A1/ru unknown
- 2014-11-06 CN CN201480066318.8A patent/CN105793439B/zh active Active
- 2014-11-06 CA CA2929547A patent/CA2929547C/en active Active
- 2014-11-06 AU AU2014346695A patent/AU2014346695B2/en active Active
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2017
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2019
- 2019-11-25 JP JP2019212462A patent/JP2020048569A/ja active Pending
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2020
- 2020-01-17 US US16/745,781 patent/US20200247879A1/en not_active Abandoned
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2022
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2023
- 2023-01-06 JP JP2023000938A patent/JP2023052239A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20160289308A1 (en) | 2016-10-06 |
| MX375701B (es) | 2025-03-06 |
| US20200247879A1 (en) | 2020-08-06 |
| US20180066045A1 (en) | 2018-03-08 |
| CN105793439A (zh) | 2016-07-20 |
| US9822172B2 (en) | 2017-11-21 |
| EP3066221A1 (en) | 2016-09-14 |
| HK1221490A1 (zh) | 2017-06-02 |
| JP2020048569A (ja) | 2020-04-02 |
| JP2023052239A (ja) | 2023-04-11 |
| CN105793439B (zh) | 2020-09-04 |
| KR102404285B1 (ko) | 2022-05-31 |
| KR20160068988A (ko) | 2016-06-15 |
| US10562961B2 (en) | 2020-02-18 |
| CA2929547A1 (en) | 2015-05-14 |
| JP2017501211A (ja) | 2017-01-12 |
| JP7277623B2 (ja) | 2023-05-19 |
| AU2014346695B2 (en) | 2020-10-15 |
| BR112016010106A2 (pt) | 2017-12-05 |
| EP3066221A4 (en) | 2017-09-20 |
| EP3556863A1 (en) | 2019-10-23 |
| WO2015069880A1 (en) | 2015-05-14 |
| AU2014346695A1 (en) | 2016-06-16 |
| CA2929547C (en) | 2023-02-28 |
| JP2022068143A (ja) | 2022-05-09 |
| EA201690731A1 (ru) | 2016-10-31 |
| MX2016005834A (es) | 2016-11-17 |
| EP3556863B1 (en) | 2024-09-18 |
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