JP2017501198A5 - - Google Patents
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- JP2017501198A5 JP2017501198A5 JP2016543740A JP2016543740A JP2017501198A5 JP 2017501198 A5 JP2017501198 A5 JP 2017501198A5 JP 2016543740 A JP2016543740 A JP 2016543740A JP 2016543740 A JP2016543740 A JP 2016543740A JP 2017501198 A5 JP2017501198 A5 JP 2017501198A5
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- JP
- Japan
- Prior art keywords
- plant
- compound
- formula
- biosynthesis inhibitor
- sterol biosynthesis
- Prior art date
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- 239000000203 mixture Substances 0.000 claims description 53
- 230000000855 fungicidal effect Effects 0.000 claims description 49
- 150000001875 compounds Chemical class 0.000 claims description 28
- 239000000417 fungicide Substances 0.000 claims description 25
- 230000002195 synergetic effect Effects 0.000 claims description 24
- 241000209140 Triticum Species 0.000 claims description 21
- 235000021307 Triticum Nutrition 0.000 claims description 21
- 229930182558 Sterol Natural products 0.000 claims description 17
- 241001360088 Zymoseptoria tritici Species 0.000 claims description 17
- 230000015572 biosynthetic process Effects 0.000 claims description 17
- 239000003112 inhibitor Substances 0.000 claims description 17
- 150000003432 sterols Chemical class 0.000 claims description 17
- 235000003702 sterols Nutrition 0.000 claims description 17
- 244000053095 fungal pathogen Species 0.000 claims description 14
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims description 13
- 241000221785 Erysiphales Species 0.000 claims description 12
- 240000005979 Hordeum vulgare Species 0.000 claims description 12
- 235000007340 Hordeum vulgare Nutrition 0.000 claims description 12
- ZMYFCFLJBGAQRS-IRXDYDNUSA-N (2R,3S)-epoxiconazole Chemical compound C1=CC(F)=CC=C1[C@@]1(CN2N=CN=C2)[C@H](C=2C(=CC=CC=2)Cl)O1 ZMYFCFLJBGAQRS-IRXDYDNUSA-N 0.000 claims description 10
- MNHVNIJQQRJYDH-UHFFFAOYSA-N 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione Chemical group N1=CNC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl MNHVNIJQQRJYDH-UHFFFAOYSA-N 0.000 claims description 10
- 239000005767 Epoxiconazole Substances 0.000 claims description 10
- 239000005825 Prothioconazole Substances 0.000 claims description 10
- UFNOUKDBUJZYDE-UHFFFAOYSA-N 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical compound C1=NC=NN1CC(O)(C=1C=CC(Cl)=CC=1)C(C)C1CC1 UFNOUKDBUJZYDE-UHFFFAOYSA-N 0.000 claims description 9
- 239000005757 Cyproconazole Substances 0.000 claims description 9
- 239000005868 Metconazole Substances 0.000 claims description 9
- 239000005822 Propiconazole Substances 0.000 claims description 9
- 201000010099 disease Diseases 0.000 claims description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 9
- XWPZUHJBOLQNMN-UHFFFAOYSA-N metconazole Chemical compound C1=NC=NN1CC1(O)C(C)(C)CCC1CC1=CC=C(Cl)C=C1 XWPZUHJBOLQNMN-UHFFFAOYSA-N 0.000 claims description 9
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 claims description 9
- 239000005760 Difenoconazole Substances 0.000 claims description 8
- 241000510928 Erysiphe necator Species 0.000 claims description 8
- BQYJATMQXGBDHF-UHFFFAOYSA-N difenoconazole Chemical compound O1C(C)COC1(C=1C(=CC(OC=2C=CC(Cl)=CC=2)=CC=1)Cl)CN1N=CN=C1 BQYJATMQXGBDHF-UHFFFAOYSA-N 0.000 claims description 8
- 239000005785 Fluquinconazole Substances 0.000 claims description 7
- 206010039509 Scab Diseases 0.000 claims description 7
- IJJVMEJXYNJXOJ-UHFFFAOYSA-N fluquinconazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1N1C(=O)C2=CC(F)=CC=C2N=C1N1C=NC=N1 IJJVMEJXYNJXOJ-UHFFFAOYSA-N 0.000 claims description 7
- 241000219104 Cucurbitaceae Species 0.000 claims description 6
- 241000540505 Puccinia dispersa f. sp. tritici Species 0.000 claims description 6
- 241000213004 Alternaria solani Species 0.000 claims description 4
- 235000016068 Berberis vulgaris Nutrition 0.000 claims description 4
- 241000335053 Beta vulgaris Species 0.000 claims description 4
- 241000895523 Blumeria graminis f. sp. hordei Species 0.000 claims description 4
- 241000895502 Blumeria graminis f. sp. tritici Species 0.000 claims description 4
- 241000530549 Cercospora beticola Species 0.000 claims description 4
- 241000222235 Colletotrichum orbiculare Species 0.000 claims description 4
- 244000068988 Glycine max Species 0.000 claims description 4
- 235000010469 Glycine max Nutrition 0.000 claims description 4
- 241000896246 Golovinomyces cichoracearum Species 0.000 claims description 4
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims description 4
- 241001344131 Magnaporthe grisea Species 0.000 claims description 4
- 240000007594 Oryza sativa Species 0.000 claims description 4
- 235000007164 Oryza sativa Nutrition 0.000 claims description 4
- 241000736122 Parastagonospora nodorum Species 0.000 claims description 4
- 241000682645 Phakopsora pachyrhizi Species 0.000 claims description 4
- 241000415582 Puccinia striiformis f. sp. tritici Species 0.000 claims description 4
- 241000520648 Pyrenophora teres Species 0.000 claims description 4
- 241001515790 Rhynchosporium secalis Species 0.000 claims description 4
- 240000003768 Solanum lycopersicum Species 0.000 claims description 4
- 244000301083 Ustilago maydis Species 0.000 claims description 4
- 235000015919 Ustilago maydis Nutrition 0.000 claims description 4
- 241000228452 Venturia inaequalis Species 0.000 claims description 4
- 240000008042 Zea mays Species 0.000 claims description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 4
- -1 flucconconazole Chemical compound 0.000 claims description 4
- 235000009566 rice Nutrition 0.000 claims description 4
- 206010035148 Plague Diseases 0.000 claims description 3
- 241000607479 Yersinia pestis Species 0.000 claims description 3
- 239000002671 adjuvant Substances 0.000 claims description 3
- 241000196324 Embryophyta Species 0.000 claims 21
- 230000002538 fungal effect Effects 0.000 claims 5
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 2
- 235000005822 corn Nutrition 0.000 claims 2
- 239000002689 soil Substances 0.000 claims 2
- RYAUSSKQMZRMAI-ALOPSCKCSA-N (2S,6R)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine Chemical compound C=1C=C(C(C)(C)C)C=CC=1CC(C)CN1C[C@H](C)O[C@H](C)C1 RYAUSSKQMZRMAI-ALOPSCKCSA-N 0.000 claims 1
- PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 claims 1
- LQDARGUHUSPFNL-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(COC(F)(F)C(F)F)CN1C=NC=N1 LQDARGUHUSPFNL-UHFFFAOYSA-N 0.000 claims 1
- PZBPHYLKIMOZPR-FIYGWYQWSA-K 2-[4-[2-[[(2r)-1-[[(4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-4-[[(2r,3r)-1,3-dihydroxybutan-2-yl]carbamoyl]-7-[(1r)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl] Chemical compound [68Ga+3].C([C@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC(O)=CC=2)NC1=O)C(=O)N[C@H](CO)[C@H](O)C)NC(=O)CN1CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)C1=CC=CC=C1 PZBPHYLKIMOZPR-FIYGWYQWSA-K 0.000 claims 1
- RQDJADAKIFFEKQ-UHFFFAOYSA-N 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)butanenitrile Chemical compound C1=CC(Cl)=CC=C1CCC(C=1C=CC=CC=1)(C#N)CN1N=CN=C1 RQDJADAKIFFEKQ-UHFFFAOYSA-N 0.000 claims 1
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 claims 1
- 241001480061 Blumeria graminis Species 0.000 claims 1
- 239000005775 Fenbuconazole Substances 0.000 claims 1
- 239000005778 Fenpropimorph Substances 0.000 claims 1
- 206010061217 Infestation Diseases 0.000 claims 1
- 206010027146 Melanoderma Diseases 0.000 claims 1
- 239000005820 Prochloraz Substances 0.000 claims 1
- 241000221300 Puccinia Species 0.000 claims 1
- 239000005839 Tebuconazole Substances 0.000 claims 1
- 239000005840 Tetraconazole Substances 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- FQKUGOMFVDPBIZ-UHFFFAOYSA-N flusilazole Chemical compound C=1C=C(F)C=CC=1[Si](C=1C=CC(F)=CC=1)(C)CN1C=NC=N1 FQKUGOMFVDPBIZ-UHFFFAOYSA-N 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 claims 1
- 150000003536 tetrazoles Chemical class 0.000 claims 1
- 241000235349 Ascomycota Species 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 241001480060 Blumeria Species 0.000 description 2
- 241000221566 Ustilago Species 0.000 description 2
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 2
- 235000009973 maize Nutrition 0.000 description 2
- 241000233866 Fungi Species 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361922616P | 2013-12-31 | 2013-12-31 | |
| US201361922640P | 2013-12-31 | 2013-12-31 | |
| US201361922630P | 2013-12-31 | 2013-12-31 | |
| US61/922,640 | 2013-12-31 | ||
| US61/922,630 | 2013-12-31 | ||
| US61/922,616 | 2013-12-31 | ||
| PCT/US2014/072745 WO2015103259A1 (en) | 2013-12-31 | 2014-12-30 | Synergistic fungicidal mixtures for fungal control in cereals |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017501198A JP2017501198A (ja) | 2017-01-12 |
| JP2017501198A5 true JP2017501198A5 (cg-RX-API-DMAC7.html) | 2018-03-01 |
| JP6609257B2 JP6609257B2 (ja) | 2019-11-20 |
Family
ID=53480350
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016543745A Active JP6608366B2 (ja) | 2013-12-31 | 2014-12-30 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2016543740A Active JP6609257B2 (ja) | 2013-12-31 | 2014-12-30 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2016543731A Active JP6767868B2 (ja) | 2013-12-31 | 2014-12-30 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2020082014A Pending JP2020143097A (ja) | 2013-12-31 | 2020-05-07 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2022076711A Pending JP2022115995A (ja) | 2013-12-31 | 2022-05-06 | 穀類における真菌防除のための相乗的殺真菌性混合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016543745A Active JP6608366B2 (ja) | 2013-12-31 | 2014-12-30 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016543731A Active JP6767868B2 (ja) | 2013-12-31 | 2014-12-30 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2020082014A Pending JP2020143097A (ja) | 2013-12-31 | 2020-05-07 | 真菌防除のための相乗的殺真菌性混合物および組成物 |
| JP2022076711A Pending JP2022115995A (ja) | 2013-12-31 | 2022-05-06 | 穀類における真菌防除のための相乗的殺真菌性混合物 |
Country Status (32)
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2015131149A (ru) | 2012-12-28 | 2017-02-03 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | N-(замещенные)-5-фтор-4-имино-3-метил-2-оксо-3,4-дигидропиримидин-1(2н)-карбоксамидные производные |
| RU2638556C2 (ru) | 2012-12-28 | 2017-12-14 | Адама Мактешим Лтд. | Производные n-(замещенного)-5-фтор-4-имино-3-метил-2-оксо-3,4-дигидропиримидин-1(2н)-карбоксилата |
| RU2644014C2 (ru) | 2012-12-31 | 2018-02-07 | Адама Мактешим Лтд. | Производные 3-алкил-5-фтор-4-замещенного-имино-3,4-дигидропиримидин-2(н)-она в качестве фунгицидов |
| PH12016501285B1 (en) | 2013-12-31 | 2022-06-17 | Adama Makhteshim Ltd | Synergistic fungicidal mixtures for fungal control in cereals |
| UA122200C2 (uk) | 2013-12-31 | 2020-10-12 | Адама Махтешім Лтд. | 5-фтор-4-іміно-3-(алкіл/заміщений алкіл)-1-(арилсульфоніл)-3,4-дигідропіримідин-2(1h)-он і способи його одержання |
| MA41272A (fr) * | 2014-12-23 | 2017-10-31 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences |
| BR122019023756B1 (pt) | 2014-12-30 | 2022-01-25 | Dow Agrosciences Llc | Composição para controle de um patógeno fúngico, e método para controle e prevenção de ataque fúngico em uma planta |
| CN105191706A (zh) * | 2015-08-20 | 2015-12-30 | 贵阳中医学院 | 一种有效防治太子参叶斑病的方法 |
| UY36964A (es) * | 2015-10-27 | 2017-05-31 | Bayer Cropscience Ag | Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida |
| WO2017110864A1 (ja) * | 2015-12-25 | 2017-06-29 | 住友化学株式会社 | 植物病害防除組成物およびその用途 |
| JP6922272B2 (ja) * | 2016-03-11 | 2021-08-18 | 住友化学株式会社 | 植物病害防除組成物及び植物病害防除方法 |
| JP6862939B2 (ja) * | 2016-03-11 | 2021-04-21 | 住友化学株式会社 | 植物病害防除組成物及び植物病害防除方法 |
| GB201610264D0 (en) * | 2016-06-13 | 2016-07-27 | Syngenta Participations Ag | Pesticidal compositions |
| UA126523C2 (uk) * | 2017-03-07 | 2022-10-26 | Юпл Лтд | Фунгіцидні комбінації |
| CN107058529B (zh) * | 2017-03-23 | 2022-01-25 | 四川省农业科学院作物研究所 | 一种选育小麦条锈病持久抗性材料的方法 |
| TW201842851A (zh) * | 2017-05-02 | 2018-12-16 | 美商陶氏農業科學公司 | 用於穀類中的真菌防治之協同性混合物 |
| TWI774761B (zh) * | 2017-05-02 | 2022-08-21 | 美商科迪華農業科技有限責任公司 | 用於穀物中的真菌防治之協同性混合物 |
| TWI774760B (zh) * | 2017-05-02 | 2022-08-21 | 美商科迪華農業科技有限責任公司 | 用於蔬菜中的真菌防治之協同性混合物 |
| TW201902357A (zh) * | 2017-05-02 | 2019-01-16 | 美商陶氏農業科學公司 | 用作種子處理之無環吡啶醯胺 |
| IL309708B1 (en) | 2017-07-17 | 2025-10-01 | Adama Makhteshim Ltd | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-4,3-dihydropyrimidin-2-one |
| CN109384728A (zh) * | 2017-08-07 | 2019-02-26 | 华东理工大学 | 嘧菌酯通道型溶剂化物及其制备方法 |
| JP7701266B2 (ja) | 2018-11-05 | 2025-07-01 | アダマ・マクテシム・リミテッド | ５－フルオロ－４－イミノ－３－メチル－１－トシル－３，４－ジヒドロピリミジン－２－オンを含む混合物および組成物、ならびにそれらの使用方法 |
| UY38798A (es) * | 2019-07-22 | 2021-02-26 | Adama Makhteshim Ltd | Combinaciones, mezclas y composiciones fungicidas y usos de las mismas |
| TWI808347B (zh) | 2019-09-23 | 2023-07-11 | 以色列商亞當馬赫特希姆有限公司 | 用於製備5-氟-4-亞胺基-3-甲基-1-甲苯磺醯基-3,4-二氫嘧啶-2(1h)-酮及該化合物的衍生物之方法 |
| CN114554848A (zh) | 2019-10-18 | 2022-05-27 | 科迪华农业科技有限责任公司 | 用于合成吡啶酰胺的方法 |
| CR20220610A (es) * | 2020-05-04 | 2023-01-10 | Adama Makhteshim Ltd | Mezclas y composiciones que comprenden 5-fluoro-4-imino-3-metil-1-tosil-3,4-dihidropirimidin-2-ona, y métodos de uso de las mismas |
| CR20230077A (es) | 2020-07-08 | 2023-07-26 | Adama Makhteshim Ltd | Mezclas fungicidas |
| CA3206570A1 (en) | 2021-01-27 | 2022-08-04 | Alexandra ROSENMUND | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1 h)-one for controlling plant diseases |
| US20240237649A1 (en) | 2021-05-04 | 2024-07-18 | Adama Makhteshim Ltd. | Crystalline forms of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and mixtures, compositions and methods of use thereof |
| PE20241992A1 (es) * | 2022-01-12 | 2024-09-27 | Adama Makhteshim Ltd | Mezclas fungicidas que comprenden combinacion que contiene fungicidas de ftalimida |
| IL315414A (en) | 2022-03-03 | 2024-11-01 | Adama Makhteshim Ltd | Combinations, mixtures and preparations of fungicides, and their uses |
| CA3257550A1 (en) | 2022-05-26 | 2023-11-30 | Adama Makhteshim Ltd. | FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND THEIR USES |
| WO2024028812A1 (en) * | 2022-08-03 | 2024-02-08 | Adama Makhteshim Ltd. | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1h)-one for fungicide-resistant fungus |
| EP4608140A1 (en) * | 2022-10-26 | 2025-09-03 | Texas Crop Science, Inc. | Antifungal compositions and methods for their use |
| WO2024105097A1 (en) * | 2022-11-17 | 2024-05-23 | Upl Mauritius Limited | Method of controlling phytopathogenic fungi |
| CN120882310A (zh) * | 2023-03-09 | 2025-10-31 | 安道麦马克西姆有限公司 | 杀真菌组合、混合物及组合物以及其用途 |
| AU2024236967A1 (en) | 2023-03-14 | 2025-09-25 | Adama Makhteshim Ltd. | Liquid compositions containing 5-(fluoro-4-imino-3-methyl)-1-tosyl-3,4 dihydropyrimidine-(1h)-one and derivatives thereof and a uv absorber |
| CN116725037A (zh) * | 2023-06-19 | 2023-09-12 | 广西壮族自治区亚热带作物研究所（广西亚热带农产品加工研究所） | 一种防治火龙果溃疡病的杀菌剂组合物 |
| WO2025031845A1 (en) * | 2023-08-09 | 2025-02-13 | Basf Se | Fungicidal compositions comprising 5-fluoro-4-imino-3-methyl-1-(p-tolylsulfonyl)pyrimidin-2-one |
| WO2025031846A1 (en) * | 2023-08-09 | 2025-02-13 | Basf Se | Fungicidal ternary mixtures comprising 5-fluoro-4-imino-3-methyl-1-(p-tolylsulfonyl)pyrimidin-2-one |
| AR133680A1 (es) * | 2023-08-31 | 2025-10-22 | Adama Makhteshim Ltd | Combinaciones, mezclas y composiciones fungicidas y usos de las mismas |
| IL308593A (en) | 2023-11-15 | 2025-06-01 | Adama Makhteshim Ltd | Reducing environmental impact of fungicidal enhancement |
| WO2025114931A1 (en) | 2023-11-28 | 2025-06-05 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
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