JP2017500277A5 - - Google Patents

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JP2017500277A5
JP2017500277A5 JP2016519876A JP2016519876A JP2017500277A5 JP 2017500277 A5 JP2017500277 A5 JP 2017500277A5 JP 2016519876 A JP2016519876 A JP 2016519876A JP 2016519876 A JP2016519876 A JP 2016519876A JP 2017500277 A5 JP2017500277 A5 JP 2017500277A5
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JP
Japan
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strand
optionally
composition
nucleotides
nucleic acid
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JP2016519876A
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English (en)
Japanese (ja)
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JP2017500277A (ja
JP6694811B2 (ja
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Priority claimed from PCT/US2014/058705 external-priority patent/WO2015051045A2/en
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Publication of JP2017500277A5 publication Critical patent/JP2017500277A5/ja
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JP2016519876A 2013-10-04 2014-10-01 ＲＮＡ干渉に使用するためのＲＮＡｉ剤用の３’末端キャップ Active JP6694811B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361886739P 2013-10-04 2013-10-04
US61/886,739 2013-10-04
PCT/US2014/058705 WO2015051045A2 (en) 2013-10-04 2014-10-01 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE

Related Child Applications (1)

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JP2019053123A Division JP6841859B2 (ja) 2013-10-04 2019-03-20 ＲＮＡ干渉に使用するためのＲＮＡｉ剤用の３’末端キャップ

Publications (3)

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JP2017500277A JP2017500277A (ja) 2017-01-05
JP2017500277A5 true JP2017500277A5 (enExample) 2017-11-09
JP6694811B2 JP6694811B2 (ja) 2020-05-20

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JP2016519876A Active JP6694811B2 (ja) 2013-10-04 2014-10-01 ＲＮＡ干渉に使用するためのＲＮＡｉ剤用の３’末端キャップ
JP2019053123A Active JP6841859B2 (ja) 2013-10-04 2019-03-20 ＲＮＡ干渉に使用するためのＲＮＡｉ剤用の３’末端キャップ

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JP2019053123A Active JP6841859B2 (ja) 2013-10-04 2019-03-20 ＲＮＡ干渉に使用するためのＲＮＡｉ剤用の３’末端キャップ

Country Status (8)

Country Link
US (2) US10227588B2 (enExample)
EP (2) EP3052464B1 (enExample)
JP (2) JP6694811B2 (enExample)
KR (1) KR102298475B1 (enExample)
CN (1) CN105683163B (enExample)
AU (2) AU2014329560B2 (enExample)
CA (2) CA3188691A1 (enExample)
WO (1) WO2015051045A2 (enExample)

Families Citing this family (6)

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HK1221912A1 (zh) 2013-10-04 2017-06-16 Novartis Ag 用於治疗乙肝病毒的有机化合物
EP3052464B1 (en) 2013-10-04 2020-04-15 Novartis AG 3'end caps for rna-interferring agents for use in rna interference
WO2015051366A2 (en) 2013-10-04 2015-04-09 Novartis Ag Novel formats for organic compounds for use in rna interference
EP3325482B1 (en) * 2015-07-21 2020-06-24 ImmunoGen, Inc. Methods of preparing cytotoxic benzodiazepine derivatives
WO2017047807A1 (ja) * 2015-09-17 2017-03-23 国立大学法人大阪大学 トラン化合物
JP6792847B2 (ja) * 2016-12-27 2020-12-02 国立大学法人 東京大学 ｍＲＮＡの機能化方法

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CN107879960B (zh) 2013-03-08 2021-06-22 诺华股份有限公司 用于传递活性成分的脂质和脂质组合物
US9504747B2 (en) 2013-03-08 2016-11-29 Novartis Ag Lipids and lipid compositions for the delivery of active agents
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EP3052464B1 (en) 2013-10-04 2020-04-15 Novartis AG 3'end caps for rna-interferring agents for use in rna interference
WO2015051135A2 (en) 2013-10-04 2015-04-09 Novartis Ag Organic compositions to treat hepcidin-related diseases
HK1221912A1 (zh) 2013-10-04 2017-06-16 Novartis Ag 用於治疗乙肝病毒的有机化合物
US10426737B2 (en) 2013-12-19 2019-10-01 Novartis Ag Lipids and lipid compositions for the delivery of active agents
EP3083556B1 (en) 2013-12-19 2019-12-25 Novartis AG Lipids and lipid compositions for the delivery of active agents
CN106794141B (zh) 2014-07-16 2021-05-28 诺华股份有限公司 将核酸包封在脂质纳米粒主体中的方法
US10125092B2 (en) 2014-09-05 2018-11-13 Novartis Ag Lipids and lipid compositions for the delivery of active agents

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