JP2017137323A5 - - Google Patents
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- Publication number
- JP2017137323A5 JP2017137323A5 JP2017037462A JP2017037462A JP2017137323A5 JP 2017137323 A5 JP2017137323 A5 JP 2017137323A5 JP 2017037462 A JP2017037462 A JP 2017037462A JP 2017037462 A JP2017037462 A JP 2017037462A JP 2017137323 A5 JP2017137323 A5 JP 2017137323A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- formula
- pharmaceutically acceptable
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000000217 alkyl group Chemical group 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000004193 piperazinyl group Chemical group 0.000 claims 2
- 125000003386 piperidinyl group Chemical group 0.000 claims 2
- 125000000719 pyrrolidinyl group Chemical group 0.000 claims 2
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical group C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 claims 1
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 0 *N(C(C(Nc1nc(*c2ccccc2)nc(*c2ccccc2)n1)N1)=O)C1=O Chemical compound *N(C(C(Nc1nc(*c2ccccc2)nc(*c2ccccc2)n1)N1)=O)C1=O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40726510P | 2010-10-27 | 2010-10-27 | |
| US61/407,265 | 2010-10-27 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535207A Division JP6184866B2 (ja) | 2010-10-27 | 2011-10-27 | 新規抗がん剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017137323A JP2017137323A (ja) | 2017-08-10 |
| JP2017137323A5 true JP2017137323A5 (OSRAM) | 2017-09-21 |
Family
ID=45992970
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535207A Expired - Fee Related JP6184866B2 (ja) | 2010-10-27 | 2011-10-27 | 新規抗がん剤 |
| JP2017037462A Pending JP2017137323A (ja) | 2010-10-27 | 2017-02-28 | 新規抗がん剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013535207A Expired - Fee Related JP6184866B2 (ja) | 2010-10-27 | 2011-10-27 | 新規抗がん剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US8835629B2 (OSRAM) |
| EP (1) | EP2632916B1 (OSRAM) |
| JP (2) | JP6184866B2 (OSRAM) |
| KR (1) | KR101896924B1 (OSRAM) |
| CN (1) | CN103476769B (OSRAM) |
| AU (1) | AU2011320024B2 (OSRAM) |
| CA (1) | CA2814120C (OSRAM) |
| ES (1) | ES2621932T3 (OSRAM) |
| HU (1) | HUE032522T2 (OSRAM) |
| NZ (1) | NZ609186A (OSRAM) |
| PL (1) | PL2632916T3 (OSRAM) |
| WO (1) | WO2012054978A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2814120C (en) * | 2010-10-27 | 2018-08-07 | The Walter And Eliza Hall Institute Of Medical Research | Novel anti-cancer agents |
| KR101853785B1 (ko) | 2013-11-20 | 2018-05-02 | 주식회사 만도 | 3상모터 제어장치 및 그의 고토크 유지 방법 |
| WO2016070241A1 (en) * | 2014-11-03 | 2016-05-12 | Ctxt Pty Ltd | Triazine compounds, compositions and synthesis |
| US20200128829A1 (en) * | 2017-06-08 | 2020-04-30 | University Of South Alabama | Antimicrobial Compounds |
| WO2019142126A1 (en) | 2018-01-17 | 2019-07-25 | Aurigene Discovery Technologies Limited | Substituted alkynylene compounds as anticancer agents |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1035771A (OSRAM) | ||||
| US2742466A (en) | 1956-04-17 | Chx n nhx c c | ||
| US3145203A (en) | 1961-11-30 | 1964-08-18 | Geigy Chem Corp | Hydrazones of 5-nitro-2-furaldehyde |
| JPS5277163A (en) | 1975-12-24 | 1977-06-29 | Asahi Chem Ind Co Ltd | Stabilized polyurethane composition |
| FR2524467A1 (fr) | 1982-03-30 | 1983-10-07 | Adir | Polymethylene-imines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| JPS62192474A (ja) | 1986-02-19 | 1987-08-24 | Canon Inc | 記録液 |
| US4932998A (en) | 1986-09-30 | 1990-06-12 | Idemitsu Kosan Company Limited | Triazine derivatives, and herbicides comprising the same as the effective ingredient |
| US4844731A (en) | 1986-12-27 | 1989-07-04 | Idemitsu Company Co., Ltd. | Triazine derivatives |
| US5187045A (en) | 1988-09-07 | 1993-02-16 | Minnesota Mining And Manufacturing Company | Halomethyl-1,3,5-triazines containing a sensitizer moiety |
| DK0411153T3 (OSRAM) | 1989-02-20 | 1997-02-10 | Idemitsu Kosan Co | |
| HUT69722A (en) | 1991-11-12 | 1995-09-28 | Pfizer | Triazine derivatives for enhancing antitumor activity |
| US5489591A (en) | 1992-02-28 | 1996-02-06 | Zenyaku Kogyo Kabushiki Kaisha | S-triazine derivative and remedy for estrogen-dependent disease containing said derivative as effective component |
| US5574057A (en) | 1993-02-03 | 1996-11-12 | University Of Utah Research Foundation | Naamidine A extracted from sea sponges and methods for its use as an anti-tumor agent |
| US6566384B1 (en) | 1996-08-07 | 2003-05-20 | Darwin Discovery Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
| FR2757056B1 (fr) | 1996-12-17 | 2003-03-14 | Oreal | Compositions comprenant un derive de dibenzoylmethane, un derive de 1,3,5-triazine et un compose amide et utilisations |
| FR2757057A1 (fr) | 1996-12-17 | 1998-06-19 | Oreal | Compositions comprenant un derive de dibenzoylmethane, un derive de 1,3,5-triazine et un derive silicie a fonction benzalmalonate et utilisations |
| EP0945447A1 (en) | 1998-03-27 | 1999-09-29 | Janssen Pharmaceutica N.V. | Trisubstituted 1,3,5-triazine derivatives for treatment of HIV infections |
| US6262053B1 (en) | 1999-06-23 | 2001-07-17 | Parker Hughes Institute | Melamine derivatives as potent anti-cancer agents |
| EP2404603A1 (en) | 2000-10-23 | 2012-01-11 | Glaxosmithkline LLC | Novel trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds for the treatment of CSBP/p38 kinase mediated diseases |
| US7173032B2 (en) * | 2001-09-21 | 2007-02-06 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| EP1441683A4 (en) * | 2001-10-12 | 2005-10-26 | Univ New York | TRISUBSTITUTED TRIAZIN COMPOUNDS AND METHOD FOR THE PREPARATION AND USE OF THE COMPOUNDS WITH ANTITUBULIN EFFECT |
| CN1697831A (zh) * | 2002-09-23 | 2005-11-16 | 雷迪美国治疗公司 | 新三嗪化合物的制备方法和组合物 |
| CA2814120C (en) * | 2010-10-27 | 2018-08-07 | The Walter And Eliza Hall Institute Of Medical Research | Novel anti-cancer agents |
-
2011
- 2011-10-27 CA CA2814120A patent/CA2814120C/en active Active
- 2011-10-27 CN CN201180059899.9A patent/CN103476769B/zh not_active Expired - Fee Related
- 2011-10-27 NZ NZ609186A patent/NZ609186A/en not_active IP Right Cessation
- 2011-10-27 WO PCT/AU2011/001376 patent/WO2012054978A1/en not_active Ceased
- 2011-10-27 JP JP2013535207A patent/JP6184866B2/ja not_active Expired - Fee Related
- 2011-10-27 AU AU2011320024A patent/AU2011320024B2/en not_active Ceased
- 2011-10-27 HU HUE11835350A patent/HUE032522T2/en unknown
- 2011-10-27 US US13/878,557 patent/US8835629B2/en active Active
- 2011-10-27 ES ES11835350.7T patent/ES2621932T3/es active Active
- 2011-10-27 PL PL11835350T patent/PL2632916T3/pl unknown
- 2011-10-27 EP EP11835350.7A patent/EP2632916B1/en not_active Not-in-force
- 2011-10-27 KR KR1020137013509A patent/KR101896924B1/ko not_active Expired - Fee Related
-
2014
- 2014-08-06 US US14/453,502 patent/US9221799B2/en active Active
-
2015
- 2015-11-19 US US14/946,368 patent/US20160145243A1/en not_active Abandoned
-
2017
- 2017-02-28 JP JP2017037462A patent/JP2017137323A/ja active Pending
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