JP2017061453A5 - - Google Patents
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- Publication number
- JP2017061453A5 JP2017061453A5 JP2016190522A JP2016190522A JP2017061453A5 JP 2017061453 A5 JP2017061453 A5 JP 2017061453A5 JP 2016190522 A JP2016190522 A JP 2016190522A JP 2016190522 A JP2016190522 A JP 2016190522A JP 2017061453 A5 JP2017061453 A5 JP 2017061453A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- administration
- composition according
- relaxin
- heart failure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12788908P | 2008-05-16 | 2008-05-16 | |
| US61/127,889 | 2008-05-16 | ||
| US19054508P | 2008-08-28 | 2008-08-28 | |
| US61/190,545 | 2008-08-28 | ||
| US20124008P | 2008-12-08 | 2008-12-08 | |
| US61/201,240 | 2008-12-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014129744A Division JP2014237648A (ja) | 2008-05-16 | 2014-06-25 | 慢性心不全の治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017061453A JP2017061453A (ja) | 2017-03-30 |
| JP2017061453A5 true JP2017061453A5 (https=) | 2017-07-13 |
Family
ID=41319370
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509781A Withdrawn JP2011520917A (ja) | 2008-05-16 | 2009-05-15 | 慢性心不全の治療方法 |
| JP2014129744A Withdrawn JP2014237648A (ja) | 2008-05-16 | 2014-06-25 | 慢性心不全の治療方法 |
| JP2016190522A Pending JP2017061453A (ja) | 2008-05-16 | 2016-09-29 | 慢性心不全の治療方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509781A Withdrawn JP2011520917A (ja) | 2008-05-16 | 2009-05-15 | 慢性心不全の治療方法 |
| JP2014129744A Withdrawn JP2014237648A (ja) | 2008-05-16 | 2014-06-25 | 慢性心不全の治療方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20110144019A1 (https=) |
| EP (2) | EP2288366A4 (https=) |
| JP (3) | JP2011520917A (https=) |
| CN (2) | CN104815319A (https=) |
| AU (1) | AU2009246112B2 (https=) |
| BR (1) | BRPI0912559A2 (https=) |
| CA (1) | CA2724535A1 (https=) |
| MX (2) | MX2010012502A (https=) |
| RU (1) | RU2512933C2 (https=) |
| WO (1) | WO2009140657A2 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2724540C (en) | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
| EP2544706B1 (en) * | 2010-03-10 | 2015-06-17 | The University Of Melbourne | Modulating aquaporins with relaxin |
| EP2646572B1 (en) * | 2010-12-01 | 2017-02-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Diagnostic and treatment of chronic heart failure |
| KR20140039257A (ko) * | 2011-07-08 | 2014-04-01 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 릴랙신을 방출하는 융합 단백질 및 이의 용도 |
| JP6276690B2 (ja) * | 2011-08-04 | 2018-02-07 | ファリス バイオテック ゲーエムベーハー | ヒトリラキシン−２を調製する方法 |
| WO2013033324A2 (en) | 2011-08-31 | 2013-03-07 | University Of Florida Research Foundation, Inc. | Materials and methods for modulating activity of bone marrow derived cells |
| EP2795338A4 (en) * | 2011-12-21 | 2015-11-04 | Nuclea Biotechnologies Inc | BIOMARKERS OF CONGESTIVE HEART FAILURE |
| CA2864100A1 (en) | 2012-02-14 | 2013-08-22 | The Regents Of The University Of California | Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions |
| AP2015008624A0 (en) * | 2013-01-25 | 2015-07-31 | Cardiorentis Ltd | Methods of treating cardiovascular indications |
| CA2928754A1 (en) * | 2013-11-07 | 2015-05-14 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Human relaxin analogue, pharmaceutical composition of same, and pharmaceutical application of same |
| US10500227B2 (en) * | 2014-12-03 | 2019-12-10 | University Of Cincinnati | Bioactive gas-encapsulated echogenic liposomes and methods for treating cardiovascular disease |
| PT3387019T (pt) | 2015-12-09 | 2022-01-14 | Scripps Research Inst | Proteínas de fusão de imunoglobulina de relaxina e métodos de uso |
| PE20191716A1 (es) | 2017-02-08 | 2019-12-05 | Bristol Myers Squibb Co | Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos |
| CN107335051A (zh) * | 2017-08-18 | 2017-11-10 | 温州医科大学附属第医院 | 一种保护慢性心衰肾功能的药物组合物 |
| CN113692284A (zh) * | 2018-11-20 | 2021-11-23 | 海德堡大学 | 用于治疗和预防心力衰竭的松弛素受体1 |
| WO2021094626A1 (en) * | 2019-11-16 | 2021-05-20 | Relaxera Pharmazeutische Gmbh & Co. Kg | Medical composition for treating cardiac wasting and cachexia |
| EP4192580A4 (en) * | 2020-08-05 | 2025-06-18 | AskBio Inc. | Methods for treating heart disease and congestive heart failure and administration of AAV vectors |
| RU2748529C1 (ru) * | 2020-09-01 | 2021-05-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ определения этиологии хронической сердечной недостаточности |
| EP4630036A1 (en) * | 2022-12-09 | 2025-10-15 | Astrazeneca AB | Dosing regimens using heterodimeric relaxin fusions |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
| US5166191A (en) | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
| WO1995000645A2 (en) | 1993-06-21 | 1995-01-05 | Genentech, Inc. | Process for producing relaxin |
| US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
| RU2213559C2 (ru) * | 2000-01-26 | 2003-10-10 | Тюменская государственная медицинская академия | Способ лечения больных хронической сердечной недостаточностью на фоне ишемической болезни сердца |
| DE10155843A1 (de) * | 2000-11-16 | 2003-01-30 | Immundiagnostik Ag | Verfahren zur Prognose und Diagnose von Herzinsuffizienz |
| US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
| EP1729817B1 (en) * | 2004-03-30 | 2014-03-05 | Industry-Academic Cooperation Foundation | Gene delivery system containing relaxin gene and pharmaceutical composition using relaxin |
| TW200800206A (en) * | 2005-07-11 | 2008-01-01 | Abbott Lab | Methods for determining how to treat congestive heart failure |
| WO2009007848A2 (en) | 2007-07-12 | 2009-01-15 | Compugen Ltd. | Bioactive peptides and method of using same |
| CA2724540C (en) * | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
-
2009
- 2009-05-15 BR BRPI0912559A patent/BRPI0912559A2/pt not_active Application Discontinuation
- 2009-05-15 MX MX2010012502A patent/MX2010012502A/es active IP Right Grant
- 2009-05-15 EP EP09747738A patent/EP2288366A4/en not_active Ceased
- 2009-05-15 MX MX2012010249A patent/MX336145B/es unknown
- 2009-05-15 AU AU2009246112A patent/AU2009246112B2/en not_active Ceased
- 2009-05-15 US US12/992,667 patent/US20110144019A1/en not_active Abandoned
- 2009-05-15 JP JP2011509781A patent/JP2011520917A/ja not_active Withdrawn
- 2009-05-15 RU RU2010151470/14A patent/RU2512933C2/ru not_active IP Right Cessation
- 2009-05-15 CN CN201510202983.1A patent/CN104815319A/zh active Pending
- 2009-05-15 CN CN2009801176516A patent/CN102026649A/zh active Pending
- 2009-05-15 EP EP16174665.6A patent/EP3150219A1/en not_active Withdrawn
- 2009-05-15 WO PCT/US2009/044247 patent/WO2009140657A2/en not_active Ceased
- 2009-05-15 CA CA2724535A patent/CA2724535A1/en not_active Abandoned
-
2013
- 2013-07-11 US US13/939,648 patent/US20140005112A1/en not_active Abandoned
-
2014
- 2014-06-25 JP JP2014129744A patent/JP2014237648A/ja not_active Withdrawn
-
2016
- 2016-04-25 US US15/137,054 patent/US20160287672A1/en not_active Abandoned
- 2016-09-29 JP JP2016190522A patent/JP2017061453A/ja active Pending
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