MX2010012502A - Metodo para el tratamiento de insuficiencia cardiaca cronica. - Google Patents
Metodo para el tratamiento de insuficiencia cardiaca cronica.Info
- Publication number
- MX2010012502A MX2010012502A MX2010012502A MX2010012502A MX2010012502A MX 2010012502 A MX2010012502 A MX 2010012502A MX 2010012502 A MX2010012502 A MX 2010012502A MX 2010012502 A MX2010012502 A MX 2010012502A MX 2010012502 A MX2010012502 A MX 2010012502A
- Authority
- MX
- Mexico
- Prior art keywords
- relaxin
- heart failure
- subject
- administration
- human
- Prior art date
Links
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Endocrinology (AREA)
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- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| US12788908P | 2008-05-16 | 2008-05-16 | |
| US19054508P | 2008-08-28 | 2008-08-28 | |
| US20124008P | 2008-12-08 | 2008-12-08 | |
| PCT/US2009/044247 WO2009140657A2 (en) | 2008-05-16 | 2009-05-15 | Method of treating chronic heart failure |
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| MX2010012502A true MX2010012502A (es) | 2011-04-11 |
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| MX2010012502A MX2010012502A (es) | 2008-05-16 | 2009-05-15 | Metodo para el tratamiento de insuficiencia cardiaca cronica. |
| MX2012010249A MX336145B (es) | 2008-05-16 | 2009-05-15 | Metodo para el tratamiento de insuficiencia cardiaca cronica. |
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| Application Number | Title | Priority Date | Filing Date |
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| MX2012010249A MX336145B (es) | 2008-05-16 | 2009-05-15 | Metodo para el tratamiento de insuficiencia cardiaca cronica. |
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| Country | Link |
|---|---|
| US (3) | US20110144019A1 (https=) |
| EP (2) | EP2288366A4 (https=) |
| JP (3) | JP2011520917A (https=) |
| CN (2) | CN104815319A (https=) |
| AU (1) | AU2009246112B2 (https=) |
| BR (1) | BRPI0912559A2 (https=) |
| CA (1) | CA2724535A1 (https=) |
| MX (2) | MX2010012502A (https=) |
| RU (1) | RU2512933C2 (https=) |
| WO (1) | WO2009140657A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2724540C (en) | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
| EP2544706B1 (en) * | 2010-03-10 | 2015-06-17 | The University Of Melbourne | Modulating aquaporins with relaxin |
| EP2646572B1 (en) * | 2010-12-01 | 2017-02-15 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Diagnostic and treatment of chronic heart failure |
| KR20140039257A (ko) * | 2011-07-08 | 2014-04-01 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 릴랙신을 방출하는 융합 단백질 및 이의 용도 |
| JP6276690B2 (ja) * | 2011-08-04 | 2018-02-07 | ファリス バイオテック ゲーエムベーハー | ヒトリラキシン−２を調製する方法 |
| WO2013033324A2 (en) | 2011-08-31 | 2013-03-07 | University Of Florida Research Foundation, Inc. | Materials and methods for modulating activity of bone marrow derived cells |
| EP2795338A4 (en) * | 2011-12-21 | 2015-11-04 | Nuclea Biotechnologies Inc | BIOMARKERS OF CONGESTIVE HEART FAILURE |
| CA2864100A1 (en) | 2012-02-14 | 2013-08-22 | The Regents Of The University Of California | Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions |
| AP2015008624A0 (en) * | 2013-01-25 | 2015-07-31 | Cardiorentis Ltd | Methods of treating cardiovascular indications |
| CA2928754A1 (en) * | 2013-11-07 | 2015-05-14 | Shanghai Hengrui Pharmaceutical Co., Ltd. | Human relaxin analogue, pharmaceutical composition of same, and pharmaceutical application of same |
| US10500227B2 (en) * | 2014-12-03 | 2019-12-10 | University Of Cincinnati | Bioactive gas-encapsulated echogenic liposomes and methods for treating cardiovascular disease |
| PT3387019T (pt) | 2015-12-09 | 2022-01-14 | Scripps Research Inst | Proteínas de fusão de imunoglobulina de relaxina e métodos de uso |
| PE20191716A1 (es) | 2017-02-08 | 2019-12-05 | Bristol Myers Squibb Co | Polipeptidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos |
| CN107335051A (zh) * | 2017-08-18 | 2017-11-10 | 温州医科大学附属第医院 | 一种保护慢性心衰肾功能的药物组合物 |
| CN113692284A (zh) * | 2018-11-20 | 2021-11-23 | 海德堡大学 | 用于治疗和预防心力衰竭的松弛素受体1 |
| WO2021094626A1 (en) * | 2019-11-16 | 2021-05-20 | Relaxera Pharmazeutische Gmbh & Co. Kg | Medical composition for treating cardiac wasting and cachexia |
| EP4192580A4 (en) * | 2020-08-05 | 2025-06-18 | AskBio Inc. | Methods for treating heart disease and congestive heart failure and administration of AAV vectors |
| RU2748529C1 (ru) * | 2020-09-01 | 2021-05-26 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр кардиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ кардиологии" Минздрава России) | Способ определения этиологии хронической сердечной недостаточности |
| EP4630036A1 (en) * | 2022-12-09 | 2025-10-15 | Astrazeneca AB | Dosing regimens using heterodimeric relaxin fusions |
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| US5023321A (en) | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
| US5166191A (en) | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
| WO1995000645A2 (en) | 1993-06-21 | 1995-01-05 | Genentech, Inc. | Process for producing relaxin |
| US5811395A (en) | 1995-06-07 | 1998-09-22 | Medical University Of South Carolina | Relaxin analogs and derivatives methods and uses thereof |
| RU2213559C2 (ru) * | 2000-01-26 | 2003-10-10 | Тюменская государственная медицинская академия | Способ лечения больных хронической сердечной недостаточностью на фоне ишемической болезни сердца |
| DE10155843A1 (de) * | 2000-11-16 | 2003-01-30 | Immundiagnostik Ag | Verfahren zur Prognose und Diagnose von Herzinsuffizienz |
| US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
| EP1729817B1 (en) * | 2004-03-30 | 2014-03-05 | Industry-Academic Cooperation Foundation | Gene delivery system containing relaxin gene and pharmaceutical composition using relaxin |
| TW200800206A (en) * | 2005-07-11 | 2008-01-01 | Abbott Lab | Methods for determining how to treat congestive heart failure |
| WO2009007848A2 (en) | 2007-07-12 | 2009-01-15 | Compugen Ltd. | Bioactive peptides and method of using same |
| CA2724540C (en) * | 2008-05-16 | 2014-07-08 | Corthera, Inc. | Treating dyspnea associated with acute heart failure with relaxin |
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2009
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- 2009-05-15 MX MX2010012502A patent/MX2010012502A/es active IP Right Grant
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- 2009-05-15 AU AU2009246112A patent/AU2009246112B2/en not_active Ceased
- 2009-05-15 US US12/992,667 patent/US20110144019A1/en not_active Abandoned
- 2009-05-15 JP JP2011509781A patent/JP2011520917A/ja not_active Withdrawn
- 2009-05-15 RU RU2010151470/14A patent/RU2512933C2/ru not_active IP Right Cessation
- 2009-05-15 CN CN201510202983.1A patent/CN104815319A/zh active Pending
- 2009-05-15 CN CN2009801176516A patent/CN102026649A/zh active Pending
- 2009-05-15 EP EP16174665.6A patent/EP3150219A1/en not_active Withdrawn
- 2009-05-15 WO PCT/US2009/044247 patent/WO2009140657A2/en not_active Ceased
- 2009-05-15 CA CA2724535A patent/CA2724535A1/en not_active Abandoned
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2013
- 2013-07-11 US US13/939,648 patent/US20140005112A1/en not_active Abandoned
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2014
- 2014-06-25 JP JP2014129744A patent/JP2014237648A/ja not_active Withdrawn
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2016
- 2016-04-25 US US15/137,054 patent/US20160287672A1/en not_active Abandoned
- 2016-09-29 JP JP2016190522A patent/JP2017061453A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009246112B2 (en) | 2013-05-02 |
| US20110144019A1 (en) | 2011-06-16 |
| EP2288366A2 (en) | 2011-03-02 |
| US20140005112A1 (en) | 2014-01-02 |
| WO2009140657A2 (en) | 2009-11-19 |
| JP2017061453A (ja) | 2017-03-30 |
| RU2010151470A (ru) | 2012-06-27 |
| MX336145B (es) | 2016-01-08 |
| RU2512933C2 (ru) | 2014-04-10 |
| US20160287672A1 (en) | 2016-10-06 |
| EP2288366A4 (en) | 2012-05-02 |
| CN102026649A (zh) | 2011-04-20 |
| BRPI0912559A2 (pt) | 2015-10-13 |
| CA2724535A1 (en) | 2009-11-19 |
| CN104815319A (zh) | 2015-08-05 |
| JP2014237648A (ja) | 2014-12-18 |
| EP3150219A1 (en) | 2017-04-05 |
| JP2011520917A (ja) | 2011-07-21 |
| AU2009246112A1 (en) | 2009-11-19 |
| WO2009140657A3 (en) | 2010-01-07 |
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| HK1151229B (en) | Relaxin for use in treating of dyspnea associated with acute heart failure |
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| FG | Grant or registration |