JP2017036288A5 - - Google Patents
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- JP2017036288A5 JP2017036288A5 JP2016175431A JP2016175431A JP2017036288A5 JP 2017036288 A5 JP2017036288 A5 JP 2017036288A5 JP 2016175431 A JP2016175431 A JP 2016175431A JP 2016175431 A JP2016175431 A JP 2016175431A JP 2017036288 A5 JP2017036288 A5 JP 2017036288A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- subject
- administered
- use according
- jak
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161480198P | 2011-04-28 | 2011-04-28 | |
| US61/480,198 | 2011-04-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508165A Division JP6363502B2 (ja) | 2011-04-28 | 2012-04-27 | Hsp90併用療法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018106047A Division JP2018153194A (ja) | 2011-04-28 | 2018-06-01 | Hsp90併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017036288A JP2017036288A (ja) | 2017-02-16 |
| JP2017036288A5 true JP2017036288A5 (https=) | 2017-07-13 |
| JP6375345B2 JP6375345B2 (ja) | 2018-08-15 |
Family
ID=47073116
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508165A Expired - Fee Related JP6363502B2 (ja) | 2011-04-28 | 2012-04-27 | Hsp90併用療法 |
| JP2016175431A Expired - Fee Related JP6375345B2 (ja) | 2011-04-28 | 2016-09-08 | Hsp90併用療法 |
| JP2018106047A Withdrawn JP2018153194A (ja) | 2011-04-28 | 2018-06-01 | Hsp90併用療法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014508165A Expired - Fee Related JP6363502B2 (ja) | 2011-04-28 | 2012-04-27 | Hsp90併用療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018106047A Withdrawn JP2018153194A (ja) | 2011-04-28 | 2018-06-01 | Hsp90併用療法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20140315929A1 (https=) |
| EP (1) | EP2701747A4 (https=) |
| JP (3) | JP6363502B2 (https=) |
| KR (2) | KR102027448B1 (https=) |
| CN (2) | CN109498812A (https=) |
| AU (3) | AU2012249322B2 (https=) |
| BR (1) | BR112013027448A2 (https=) |
| CA (1) | CA2833390A1 (https=) |
| EA (1) | EA201391587A1 (https=) |
| MX (1) | MX2013012183A (https=) |
| NZ (1) | NZ618062A (https=) |
| WO (1) | WO2012149493A2 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201490230A1 (ru) | 2011-07-08 | 2014-06-30 | Слоан-Кеттеринг Инститьют Фор Кэнсер Рисерч | Применение меченых ингибиторов hsp90 |
| US20140079636A1 (en) * | 2012-04-16 | 2014-03-20 | Dinesh U. Chimmanamada | Targeted therapeutics |
| DK2935222T3 (en) | 2012-12-21 | 2019-01-07 | Epizyme Inc | PRMT5 INHIBITORS AND APPLICATIONS THEREOF |
| US10071130B2 (en) | 2013-12-12 | 2018-09-11 | The University Of Chicago | Methods and compositions related to Hsp90 inhibitors and breast cancer |
| WO2015138039A1 (en) | 2013-12-23 | 2015-09-17 | Memorial Sloan-Kettering Cancer Center | Methods and reagents for radiolabeling |
| WO2015168599A1 (en) * | 2014-05-02 | 2015-11-05 | The Wistar Institute Of Anatomy And Biology | Combination therapies targeting mitochondria for cancer therapy |
| MX387627B (es) | 2014-09-17 | 2025-03-18 | Memorial Sloan Kettering Cancer Center | Formación de imágenes de inflamación e infección dirigida a hsp90 y terapia |
| US10409955B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions |
| US10346592B2 (en) | 2014-10-21 | 2019-07-09 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10073952B2 (en) | 2014-10-21 | 2018-09-11 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10793907B2 (en) | 2014-10-21 | 2020-10-06 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US9754080B2 (en) | 2014-10-21 | 2017-09-05 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cardiovascular disease conditions |
| US9710606B2 (en) | 2014-10-21 | 2017-07-18 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10388407B2 (en) | 2014-10-21 | 2019-08-20 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| US11783914B2 (en) | 2014-10-21 | 2023-10-10 | Psomagen, Inc. | Method and system for panel characterizations |
| US10366793B2 (en) | 2014-10-21 | 2019-07-30 | uBiome, Inc. | Method and system for characterizing microorganism-related conditions |
| US10357157B2 (en) | 2014-10-21 | 2019-07-23 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features |
| US9758839B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features |
| US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| WO2016065075A1 (en) | 2014-10-21 | 2016-04-28 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
| US10789334B2 (en) | 2014-10-21 | 2020-09-29 | Psomagen, Inc. | Method and system for microbial pharmacogenomics |
| US10265009B2 (en) | 2014-10-21 | 2019-04-23 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features |
| US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
| US10395777B2 (en) | 2014-10-21 | 2019-08-27 | uBiome, Inc. | Method and system for characterizing microorganism-associated sleep-related conditions |
| US10381112B2 (en) | 2014-10-21 | 2019-08-13 | uBiome, Inc. | Method and system for characterizing allergy-related conditions associated with microorganisms |
| US10777320B2 (en) | 2014-10-21 | 2020-09-15 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for mental health associated conditions |
| US9760676B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US10311973B2 (en) | 2014-10-21 | 2019-06-04 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10325685B2 (en) | 2014-10-21 | 2019-06-18 | uBiome, Inc. | Method and system for characterizing diet-related conditions |
| WO2016168344A1 (en) * | 2015-04-13 | 2016-10-20 | uBiome, Inc. | Method and system for microbiome-derived characterization, diaganostics and therapeutics for conditions associated with functional features |
| US10246753B2 (en) | 2015-04-13 | 2019-04-02 | uBiome, Inc. | Method and system for characterizing mouth-associated conditions |
| CN106265660B (zh) * | 2015-05-21 | 2019-08-02 | 中国科学院合肥物质科学研究院 | A674563在携带flt3突变型基因的急性白血病中的用途 |
| CN106349180B (zh) * | 2015-07-14 | 2020-05-19 | 上海翰森生物医药科技有限公司 | 4,5-二苯基异噁唑衍生物及其制备方法和应用 |
| JP7187035B2 (ja) * | 2016-08-03 | 2022-12-12 | アールイーエムディー バイオセラピューティクス,インコーポレイテッド | 癌を治療するためのグルカゴン受容体アンタゴニストとpi3k経路阻害剤との組み合わせ |
| EP3576794A1 (en) * | 2017-02-03 | 2019-12-11 | AI Therapeutics, Inc. | Methods for treating cancer using hsp90 inhibitors |
| CA3067572A1 (en) | 2017-06-20 | 2018-12-27 | Madrigal Pharmaceuticals, Inc. | Targeted therapeutics |
| KR20200016874A (ko) | 2017-06-20 | 2020-02-17 | 마드리갈 파마슈티칼스 인코포레이티드 | 표적화 치료제를 포함하는 병용 요법 |
| WO2020117715A1 (en) | 2018-12-03 | 2020-06-11 | Board Of Regents, The University Of Texas System | Oligo-benzamide analogs and their use in cancer treatment |
| CN109554343B (zh) * | 2018-12-29 | 2022-04-19 | 吉林大学 | 一种适于神经元粘附与存活的涂层材料及制备方法 |
| WO2020206608A1 (en) | 2019-04-09 | 2020-10-15 | Ranok Therapeutics (Hangzhou) Co., Ltd. | Methods and compositions for targeted protein degradation |
| CN111467472B (zh) * | 2020-04-21 | 2020-12-25 | 南京中医药大学 | 一种靶向肿瘤相关巨噬细胞的免疫调节微球制剂及其制备方法与应用 |
| US20230218577A1 (en) * | 2020-06-11 | 2023-07-13 | The Children's Medical Center Corporation | Use of heat shock protein inhibitors for the treatment of neurodevelopmental disorders |
| CN116390723B (zh) | 2020-09-09 | 2024-12-31 | 社会利益网络公司 | 用于将生物素递送至线粒体的方法和组合物 |
| MX2023004373A (es) * | 2020-10-14 | 2023-07-07 | Ranok Therapeutics Hangzhou Co Ltd | Metodos y composiciones para la degradacion dirigida de proteinas. |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6303652B1 (en) * | 1998-08-21 | 2001-10-16 | Hughes Institute | BTK inhibitors and methods for their identification and use |
| WO2007035963A2 (en) | 2005-09-23 | 2007-03-29 | Conforma Therapeutics Corporation | Anti-tumor methods using multi drug resistance independent synthetic hsp90 inhibitors |
| EP2073802A1 (en) * | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US20100069458A1 (en) * | 2007-02-15 | 2010-03-18 | Peter Wisdom Atadja | Combination of lbh589 with other therapeutic agents for treating cancer |
| WO2008114812A1 (ja) * | 2007-03-19 | 2008-09-25 | Kyowa Hakko Kirin Co., Ltd. | Jak阻害剤 |
| EA032294B1 (ru) * | 2007-07-30 | 2019-05-31 | Арди Байосайенсиз, Инк. | Способ получения полиморфной формы производного n-(ариламино)сульфонамида, фармацевтическая композиция, содержащая указанное производное, и способ лечения с помощью указанного производного |
| US20100310563A1 (en) * | 2007-11-30 | 2010-12-09 | Bumm Thomas G P | Methods for treating induced cellular proliferative disorders |
| US20110224223A1 (en) * | 2008-07-08 | 2011-09-15 | The Regents Of The University Of California, A California Corporation | MTOR Modulators and Uses Thereof |
| CN102216775B (zh) * | 2008-08-18 | 2014-04-16 | 马克斯·普朗克科学促进协会 | 对hsp90-抑制剂的易感性 |
| MA32934B1 (fr) * | 2008-11-28 | 2012-01-02 | Novartis Ag | Combinaisons inhibitrices hsp90 |
| US8669289B2 (en) * | 2009-04-24 | 2014-03-11 | The Jackson Laboratory | Methods and compositions relating to hematologic malignancies |
| WO2010147898A2 (en) * | 2009-06-15 | 2010-12-23 | Rigel Pharmaceuticals, Inc. | Small molecule inhibitors of spleen tyrosine kinase (syk) |
| NZ713361A (en) * | 2009-08-17 | 2017-06-30 | Memorial Sloan Kettering Cancer Center | Heat shock protein binding compounds, compositions, and methods for making and using same |
| AU2010319322A1 (en) * | 2009-11-13 | 2012-05-31 | Infinity Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
| CA3007787C (en) * | 2010-06-03 | 2020-03-10 | Pharmacyclics Llc | The use of inhibitors of bruton's tyrosine kinase (btk) |
| EP2714038A1 (en) * | 2011-05-24 | 2014-04-09 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitory compounds with mtor/pi3k inhibitors |
-
2012
- 2012-04-27 BR BR112013027448-4A patent/BR112013027448A2/pt not_active IP Right Cessation
- 2012-04-27 CN CN201811083946.3A patent/CN109498812A/zh active Pending
- 2012-04-27 CN CN201280030064.5A patent/CN103998935B/zh not_active Expired - Fee Related
- 2012-04-27 AU AU2012249322A patent/AU2012249322B2/en not_active Ceased
- 2012-04-27 US US14/113,779 patent/US20140315929A1/en not_active Abandoned
- 2012-04-27 JP JP2014508165A patent/JP6363502B2/ja not_active Expired - Fee Related
- 2012-04-27 EA EA201391587A patent/EA201391587A1/ru unknown
- 2012-04-27 NZ NZ618062A patent/NZ618062A/en not_active IP Right Cessation
- 2012-04-27 KR KR1020137031561A patent/KR102027448B1/ko not_active Expired - Fee Related
- 2012-04-27 CA CA2833390A patent/CA2833390A1/en not_active Abandoned
- 2012-04-27 KR KR1020197028143A patent/KR102196424B1/ko not_active Expired - Fee Related
- 2012-04-27 WO PCT/US2012/035690 patent/WO2012149493A2/en not_active Ceased
- 2012-04-27 EP EP12777773.8A patent/EP2701747A4/en not_active Withdrawn
- 2012-04-27 MX MX2013012183A patent/MX2013012183A/es unknown
-
2016
- 2016-09-08 JP JP2016175431A patent/JP6375345B2/ja not_active Expired - Fee Related
-
2017
- 2017-12-08 AU AU2017272303A patent/AU2017272303A1/en not_active Abandoned
-
2018
- 2018-06-01 JP JP2018106047A patent/JP2018153194A/ja not_active Withdrawn
-
2020
- 2020-01-14 AU AU2020200262A patent/AU2020200262A1/en not_active Abandoned
- 2020-08-28 US US17/006,359 patent/US20220074941A1/en not_active Abandoned
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