JP2016540809A5 - - Google Patents
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- Publication number
- JP2016540809A5 JP2016540809A5 JP2016540677A JP2016540677A JP2016540809A5 JP 2016540809 A5 JP2016540809 A5 JP 2016540809A5 JP 2016540677 A JP2016540677 A JP 2016540677A JP 2016540677 A JP2016540677 A JP 2016540677A JP 2016540809 A5 JP2016540809 A5 JP 2016540809A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- pharmaceutical composition
- isoxazoline compound
- potable water
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 methoxyethyl Chemical group 0.000 claims 28
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 239000003651 drinking water Substances 0.000 claims 9
- 241001465754 Metazoa Species 0.000 claims 7
- 235000012206 bottled water Nutrition 0.000 claims 7
- 229920000136 polysorbate Polymers 0.000 claims 6
- 229950008882 polysorbate Drugs 0.000 claims 6
- 239000004094 surface-active agent Substances 0.000 claims 6
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 claims 5
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 5
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 150000002367 halogens Chemical class 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 3
- 230000009545 invasion Effects 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 3
- XEUCQOBUZPQUMQ-UHFFFAOYSA-N Glycolone Chemical compound COC1=C(CC=C(C)C)C(=O)NC2=C1C=CC=C2OC XEUCQOBUZPQUMQ-UHFFFAOYSA-N 0.000 claims 2
- 235000020188 drinking water Nutrition 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 125000005745 ethoxymethyl group Chemical group [H]C([H])([H])C([H])([H])OC([H])([H])* 0.000 claims 2
- 125000004970 halomethyl group Chemical group 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 claims 2
- 244000045947 parasite Species 0.000 claims 2
- 125000005767 propoxymethyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])[#8]C([H])([H])* 0.000 claims 2
- 206010061217 Infestation Diseases 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 239000002518 antifoaming agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000006255 cyclopropyl carbonyl group Chemical group [H]C1([H])C([H])([H])C1([H])C(*)=O 0.000 claims 1
- 238000007865 diluting Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000006260 ethylaminocarbonyl group Chemical group [H]N(C(*)=O)C([H])([H])C([H])([H])[H] 0.000 claims 1
- 125000004672 ethylcarbonyl group Chemical group [H]C([H])([H])C([H])([H])C(*)=O 0.000 claims 1
- 229920005555 halobutyl Polymers 0.000 claims 1
- 125000004968 halobutyl group Chemical group 0.000 claims 1
- 125000004969 haloethyl group Chemical group 0.000 claims 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 1
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229920000728 polyester Polymers 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 244000144977 poultry Species 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 125000004673 propylcarbonyl group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 claims 1
- 201000001064 tick infestation Diseases 0.000 claims 1
- 0 CC(C1)=NOC1(*)C1=C*(*=*)C=CC=C1 Chemical compound CC(C1)=NOC1(*)C1=C*(*=*)C=CC=C1 0.000 description 6
- XNTFQMKXUFFUQO-UHFFFAOYSA-N C[n]1nccc1CN Chemical compound C[n]1nccc1CN XNTFQMKXUFFUQO-UHFFFAOYSA-N 0.000 description 1
- QYOJSNPPGRBNJR-UHFFFAOYSA-N NC(C1)CS1(=O)=O Chemical compound NC(C1)CS1(=O)=O QYOJSNPPGRBNJR-UHFFFAOYSA-N 0.000 description 1
- OZGWIFFWPCEUEE-UHFFFAOYSA-N NC(C1)CS1=O Chemical compound NC(C1)CS1=O OZGWIFFWPCEUEE-UHFFFAOYSA-N 0.000 description 1
- YFEQTUUFQKDATK-UHFFFAOYSA-N NCc1c[s]cn1 Chemical compound NCc1c[s]cn1 YFEQTUUFQKDATK-UHFFFAOYSA-N 0.000 description 1
- WOXFMYVTSLAQMO-UHFFFAOYSA-N NCc1ccccn1 Chemical compound NCc1ccccn1 WOXFMYVTSLAQMO-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13199006 | 2013-12-20 | ||
| EP13199006.1 | 2013-12-20 | ||
| PCT/EP2014/078634 WO2015091898A1 (en) | 2013-12-20 | 2014-12-19 | Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016540809A JP2016540809A (ja) | 2016-12-28 |
| JP2016540809A5 true JP2016540809A5 (https=) | 2018-01-25 |
| JP6581586B2 JP6581586B2 (ja) | 2019-09-25 |
Family
ID=49880542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540677A Active JP6581586B2 (ja) | 2013-12-20 | 2014-12-19 | イソオキサゾリン組成物および動物における寄生虫侵襲の予防または処置におけるその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US10456358B2 (https=) |
| EP (2) | EP3082867B1 (https=) |
| JP (1) | JP6581586B2 (https=) |
| CN (2) | CN105813651B (https=) |
| ES (2) | ES3036365T3 (https=) |
| HU (2) | HUE066811T2 (https=) |
| MX (1) | MX373872B (https=) |
| PL (2) | PL4306168T3 (https=) |
| PT (1) | PT4306168T (https=) |
| RU (1) | RU2688919C1 (https=) |
| WO (1) | WO2015091898A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3082867B1 (en) | 2013-12-20 | 2024-01-17 | Intervet International B.V. | Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals |
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| EP3236960B1 (en) * | 2014-12-22 | 2025-01-29 | Intervet International B.V. | Fluralaner for use in the treatment of demodicosis |
| BR112017027855B1 (pt) | 2015-06-23 | 2022-11-16 | Intervet International B.V. | Composição farmacêutica, seu uso, água potável medicamentosa e método para sua preparação |
| WO2018039508A1 (en) * | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| JP2020503369A (ja) * | 2016-10-31 | 2020-01-30 | ザ・スクリップス・リサーチ・インスティテュート | 媒介体由来疾患伝染を予防する方法と組成物 |
| KR102694519B1 (ko) | 2017-11-07 | 2024-08-13 | 인터벳 인터내셔널 비.브이. | 큰 크기의 이속사졸린 입자를 제조하는 방법 |
| PE20201150A1 (es) * | 2017-11-07 | 2020-10-26 | Intervet Int Bv | Composiciones farmaceuticas inyectables de isoxazolina y usos de las mismas |
| WO2019118928A1 (en) | 2017-12-15 | 2019-06-20 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| WO2019121844A1 (en) * | 2017-12-20 | 2019-06-27 | Intervet International B.V. | System for external fish parasite monitoring in aquaculture |
| US12127535B2 (en) | 2017-12-20 | 2024-10-29 | Intervet Inc. | Method and system for external fish parasite monitoring in aquaculture |
| CN116034916B (zh) | 2017-12-20 | 2026-01-02 | 英特维特国际股份有限公司 | 用于水产养殖中的鱼外部寄生虫监测的方法和系统 |
| US11825814B2 (en) | 2017-12-20 | 2023-11-28 | Intervet Inc. | System for external fish parasite monitoring in aquaculture |
| CN111491508B (zh) * | 2017-12-20 | 2022-05-24 | 英特维特国际股份有限公司 | 用于水产养殖中的鱼外部寄生虫监测的系统 |
| KR102142916B1 (ko) * | 2018-08-17 | 2020-08-10 | 부산대학교 산학협력단 | 상향식 방법을 통한 난용성 약물을 포함하는 나노현탁액의 제조방법 및 이로 제조된 나노현탁액 |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| EP3986377A4 (en) * | 2019-06-19 | 2023-07-19 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| US20220249445A1 (en) * | 2019-06-19 | 2022-08-11 | Tarsus Pharmaceuticals, Inc. | Isoxazoline parasiticide formulations and methods for treating blepharitis |
| EP4077286A1 (en) | 2019-12-18 | 2022-10-26 | Elanco Tiergesundheit AG | Isoxazoline derivatives as pesticides |
| KR20230043904A (ko) | 2020-07-24 | 2023-03-31 | 엘랑코 유에스 인코포레이티드 | 이속사졸린 화합물 및 이의 중간체의 제조 공정 |
| CN116744917A (zh) | 2020-09-04 | 2023-09-12 | 礼蓝美国公司 | 适口调配物 |
| JP2024511956A (ja) * | 2021-03-11 | 2024-03-18 | イン ザ ボウル アニマル ヘルス，インコーポレーテッド | 経口のイヌ科動物の飼料およびイヌ科動物におけるダニの侵入を制御する方法 |
| CN114306231B (zh) * | 2021-12-29 | 2023-03-24 | 天津市中升挑战生物科技有限公司 | 一种氟雷拉纳杀虫剂及其制备方法和应用 |
| CN117064851B (zh) * | 2023-09-20 | 2026-02-17 | 中国农业大学 | 一种异噁唑啉类驱虫药制剂的制备方法 |
| PL449854A1 (pl) * | 2024-09-18 | 2026-03-23 | Okoniewski Piotr | Kompozycja farmaceutyczna, lecznicza woda pitna, ich zastosowanie i sposób wytwarzania leczniczej wody pitnej |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3727648A1 (de) | 1987-08-19 | 1989-03-02 | Bayer Ag | Neue avermectin derivate, verfahren zu ihrer herstellung und ihre verwendung |
| US6998131B2 (en) * | 1996-09-19 | 2006-02-14 | Merial Limited | Spot-on formulations for combating parasites |
| CN101768129B (zh) | 2004-03-05 | 2012-05-23 | 日产化学工业株式会社 | 异*唑啉取代苯甲酰胺化合物的制备中间体 |
| AU2006313007C1 (en) * | 2005-11-10 | 2019-10-03 | Elanco Australasia Pty Limited | Method of treating parasites |
| TW200803740A (en) | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| KR101769728B1 (ko) * | 2007-06-27 | 2017-08-18 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 동물 해충 방제 방법 |
| TWI556741B (zh) * | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
| TWI411395B (zh) | 2007-12-24 | 2013-10-11 | Syngenta Participations Ag | 殺蟲化合物 |
| CN102149695B (zh) | 2008-07-09 | 2015-02-04 | 日产化学工业株式会社 | 异*唑啉取代的苯甲酰胺化合物的制造方法 |
| CN102088856B (zh) * | 2008-07-09 | 2015-11-25 | 巴斯夫欧洲公司 | 包含异*唑啉化合物的杀虫活性混合物i |
| MY155497A (en) * | 2008-11-19 | 2015-10-30 | Merial Inc | Compositions comprising an aryl pyrazole and/or a formamidine, methods and use thereof |
| US8377942B2 (en) | 2008-12-18 | 2013-02-19 | Novartis Ag | Isoxazolines derivatives and their use as pesticide |
| HUE015568T4 (en) | 2008-12-19 | 2017-10-30 | Elanco Tiergesundheit Ag | Isoxazoline derivatives and their use as pesticides |
| CN102596968B (zh) | 2009-07-30 | 2015-05-06 | 梅里亚有限公司 | 杀虫的4-氨基-噻吩并[2,3-d]-嘧啶化合物及其使用方法 |
| AR081843A1 (es) | 2010-06-09 | 2012-10-24 | Syngenta Participations Ag | Mezclas pesticidas incluyendo derivados isoxazolina |
| DK178277B1 (da) | 2010-06-18 | 2015-10-26 | Novartis Tiergesundheit Ag | Diaryloxazolinforbindelser til bekæmpelse af fiskelus |
| JP6002148B2 (ja) | 2010-12-27 | 2016-10-05 | インターベット インターナショナル ベー． フェー． | 経表面局所イソオキサゾリン製剤 |
| NZ611474A (en) * | 2010-12-27 | 2015-08-28 | Intervet Int Bv | Topical localized isoxazoline formulation comprising glycofurol |
| JP2014505089A (ja) | 2011-02-10 | 2014-02-27 | ノバルティス アーゲー | 無脊椎有害動物を防除するためのイソオキサゾリン誘導体 |
| ME02412B (me) | 2011-03-10 | 2016-09-20 | Zoetis Services Llc | Spirociklični derivati izoksazolina kao antiparazitska sredstva |
| CN106045962A (zh) | 2011-08-25 | 2016-10-26 | 先正达参股股份有限公司 | 作为杀虫化合物的异噁唑啉衍生物 |
| WO2013026695A1 (en) | 2011-08-25 | 2013-02-28 | Syngenta Participations Ag | Isoxazoline derivatives as insecticidal compounds |
| RS58417B1 (sr) | 2011-09-12 | 2019-04-30 | Merial Inc | Paraziticidne kompozicije koje sadrže izoksazolinsko aktivno sredstvo, postupci i upotrebe povezane sa njima |
| WO2013050302A1 (en) | 2011-10-03 | 2013-04-11 | Syngenta Participations Ag | Isoxazoline derivatives as insecticidal compounds |
| WO2013150055A1 (en) | 2012-04-04 | 2013-10-10 | Intervet International B.V. | Solid oral pharmaceutical compositions for isoxazoline compounds |
| AU2014324837B2 (en) | 2013-09-30 | 2019-01-17 | Zoetis Services Llc | Long-acting spiro-isoxazoline formulations |
| EP3082806B1 (en) | 2013-12-20 | 2021-05-12 | Intervet International B.V. | Use of isoxazoline derivatives for the treatment or prevention of arthropod infestations in poultry |
| EP3082867B1 (en) | 2013-12-20 | 2024-01-17 | Intervet International B.V. | Isoxazoline compositions and use thereof in the prevention or treatment of parasite infestations in animals |
-
2014
- 2014-12-19 EP EP14815365.3A patent/EP3082867B1/en active Active
- 2014-12-19 RU RU2016129474A patent/RU2688919C1/ru active
- 2014-12-19 CN CN201480068585.9A patent/CN105813651B/zh active Active
- 2014-12-19 US US15/102,414 patent/US10456358B2/en active Active
- 2014-12-19 CN CN201910734505.3A patent/CN110327468B/zh active Active
- 2014-12-19 HU HUE14815365A patent/HUE066811T2/hu unknown
- 2014-12-19 ES ES23206906T patent/ES3036365T3/es active Active
- 2014-12-19 MX MX2016008118A patent/MX373872B/es active IP Right Grant
- 2014-12-19 JP JP2016540677A patent/JP6581586B2/ja active Active
- 2014-12-19 WO PCT/EP2014/078634 patent/WO2015091898A1/en not_active Ceased
- 2014-12-19 ES ES14815365T patent/ES2971061T3/es active Active
- 2014-12-19 EP EP23206906.2A patent/EP4306168B1/en active Active
- 2014-12-19 HU HUE23206906A patent/HUE072822T2/hu unknown
- 2014-12-19 PL PL23206906.2T patent/PL4306168T3/pl unknown
- 2014-12-19 PT PT232069062T patent/PT4306168T/pt unknown
- 2014-12-19 PL PL14815365.3T patent/PL3082867T3/pl unknown
-
2019
- 2019-09-13 US US16/570,633 patent/US20200000720A1/en not_active Abandoned
-
2021
- 2021-07-30 US US17/390,296 patent/US11883530B2/en active Active
-
2023
- 2023-12-06 US US18/530,282 patent/US20240122849A1/en not_active Abandoned
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