|
US5437291A
(en)
|
1993-08-26 |
1995-08-01 |
Univ Johns Hopkins |
Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
|
|
US6974578B1
(en)
|
1993-12-28 |
2005-12-13 |
Allergan, Inc. |
Method for treating secretions and glands using botulinum toxin
|
|
US5766605A
(en)
|
1994-04-15 |
1998-06-16 |
Mount Sinai School Of Medicine Of The City University Of New York |
Treatment of autonomic nerve dysfunction with botulinum toxin
|
|
DK0758900T3
(da)
*
|
1994-05-09 |
2002-07-29 |
William J Binder |
Botulinumtoksin til reduktion af migræne-hovedpinesmerter
|
|
US5670484A
(en)
|
1994-05-09 |
1997-09-23 |
Binder; William J. |
Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders
|
|
US6063768A
(en)
|
1997-09-04 |
2000-05-16 |
First; Eric R. |
Application of botulinum toxin to the management of neurogenic inflammatory disorders
|
|
US6265379B1
(en)
|
1999-10-13 |
2001-07-24 |
Allergan Sales, Inc. |
Method for treating otic disorders
|
|
US6139845A
(en)
|
1999-12-07 |
2000-10-31 |
Allergan Sales, Inc. |
Method for treating cancer with a neurotoxin
|
|
US20030118598A1
(en)
*
|
2000-02-08 |
2003-06-26 |
Allergan, Inc. |
Clostridial toxin pharmaceutical compositions
|
|
US7780967B2
(en)
*
|
2000-02-08 |
2010-08-24 |
Allergan, Inc. |
Reduced toxicity Clostridial toxin pharmaceutical compositions
|
|
US20060269575A1
(en)
*
|
2000-02-08 |
2006-11-30 |
Allergan, Inc. |
Botulinum toxin pharmaceutical compositions formulated with recombinant albumin
|
|
US8632785B2
(en)
*
|
2000-02-08 |
2014-01-21 |
Allergan, Inc. |
Clostridial toxin pharmaceutical composition containing a gelatin fragment
|
|
US6464986B1
(en)
|
2000-04-14 |
2002-10-15 |
Allegan Sales, Inc. |
Method for treating pain by peripheral administration of a neurotoxin
|
|
US6299893B1
(en)
|
2000-04-17 |
2001-10-09 |
Marvin Schwartz |
Method to reduce hair loss and stimulate hair regrowth
|
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
|
US6423319B1
(en)
|
2000-10-04 |
2002-07-23 |
Allergan Sales, Inc. |
Methods for treating muscle injuries
|
|
EP1411978B1
(en)
|
2001-07-27 |
2008-09-03 |
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College |
Botulinum toxin in the treatment or prevention of acne
|
|
MXPA01011542A
(es)
*
|
2001-11-13 |
2003-05-22 |
Alcon Inc |
Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
|
|
US7691394B2
(en)
*
|
2002-05-28 |
2010-04-06 |
Botulinum Toxin Research Associates, Inc. |
High-potency botulinum toxin formulations
|
|
US7459164B2
(en)
|
2002-05-28 |
2008-12-02 |
Botulinum Toxin Research Associates, Inc. |
Composition for therapeutic and cosmetic botulinum toxin
|
|
AU2003231878A1
(en)
|
2002-05-31 |
2003-12-19 |
Solux Corporation |
Pharmaceutical preparation of botulinum neurotoxin, methods of synthesis and methods of clinical use
|
|
AU2003300666A1
(en)
*
|
2002-12-20 |
2004-07-29 |
Botulinum Toxin Research Associates, Inc. |
Pharmaceutical botulinum toxin compositions
|
|
US7396535B2
(en)
*
|
2003-04-25 |
2008-07-08 |
Ackerman Alan H |
Therapy for obsessive compulsive head banging
|
|
DE10333317A1
(de)
|
2003-07-22 |
2005-02-17 |
Biotecon Therapeutics Gmbh |
Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
|
|
US7160699B2
(en)
*
|
2003-09-25 |
2007-01-09 |
Allergan, Inc. |
Media for clostridium bacterium and processes for obtaining a clostridial toxin
|
|
US7354740B2
(en)
*
|
2003-09-25 |
2008-04-08 |
Allergan, Inc. |
Animal product free system and process for purifying a botulinum toxin
|
|
US9078892B2
(en)
*
|
2004-02-26 |
2015-07-14 |
Allergan, Inc. |
Methods for treating pain and for treating a medication overuse disorder
|
|
US20100266638A1
(en)
*
|
2004-02-26 |
2010-10-21 |
Allergan, Inc. |
Headache treatment method
|
|
US20050191321A1
(en)
*
|
2004-02-26 |
2005-09-01 |
Allergan, Inc. |
Methods for treating headache
|
|
GB2416122A
(en)
|
2004-07-12 |
2006-01-18 |
Ipsen Ltd |
Botulinum neurotoxin composition
|
|
BRPI0513850A
(pt)
*
|
2004-07-26 |
2008-05-20 |
Merz Pharma Gmbh & Co Kgaa |
composição terapêutica com uma neurotoxina botulìnica
|
|
EP3210620A1
(en)
*
|
2004-08-04 |
2017-08-30 |
Ipsen Biopharm Limited |
Pharmaceutical composition containing botulinum neurotoxin a2
|
|
US20060073208A1
(en)
*
|
2004-10-01 |
2006-04-06 |
Allergan, Inc. |
Cosmetic neurotoxin compositions and methods
|
|
US20090214466A1
(en)
*
|
2005-05-09 |
2009-08-27 |
Levin Bruce H |
Methods of Alleviating Disorders and Their Associated Pain
|
|
US8926991B2
(en)
*
|
2005-06-14 |
2015-01-06 |
Botulinum Toxin Research Associates, Inc. |
Botulinum toxin and the treatment of primary disorders of mood and affect
|
|
US8323666B2
(en)
*
|
2005-08-01 |
2012-12-04 |
Allergan, Inc. |
Botulinum toxin compositions
|
|
US7744904B1
(en)
*
|
2005-09-26 |
2010-06-29 |
B.B. Scientific L.L.C. |
Stabilization of Clostridium botulinum neurotoxin complex
|
|
US8137677B2
(en)
*
|
2005-10-06 |
2012-03-20 |
Allergan, Inc. |
Non-protein stabilized clostridial toxin pharmaceutical compositions
|
|
US8168206B1
(en)
*
|
2005-10-06 |
2012-05-01 |
Allergan, Inc. |
Animal protein-free pharmaceutical compositions
|
|
US20090324647A1
(en)
*
|
2005-10-11 |
2009-12-31 |
Borodic Gary E |
Albumin-Free Botulinum Toxin Based Pharmaceutical Compositions Containing a Hyaluronidase and Methods of Use
|
|
US9061025B2
(en)
*
|
2006-08-31 |
2015-06-23 |
Allergan, Inc. |
Methods for selecting headache patients responsive to botulinum toxin therapy
|
|
FR2910327B1
(fr)
|
2006-12-22 |
2013-04-26 |
Scras |
Utilisation d'au moins une neurotoxine botulique pour traiter la douleur induite par les traitements therapeutiques du virus du sida.
|
|
BRPI0813948B8
(pt)
*
|
2007-07-10 |
2021-05-25 |
Medy Tox Inc |
composição líquida farmacêutica de toxina botulínica com estabilidade melhorada
|
|
US9044477B2
(en)
*
|
2007-12-12 |
2015-06-02 |
Allergan, Inc. |
Botulinum toxin formulation
|
|
US9161970B2
(en)
*
|
2007-12-12 |
2015-10-20 |
Allergan, Inc. |
Dermal filler
|
|
EP2072039A1
(en)
*
|
2007-12-21 |
2009-06-24 |
Merz Pharma GmbH & Co.KGaA |
Use of a neurotoxic component of Clostridium botulinum toxin complex to reduce or prevent side effects
|
|
US9107815B2
(en)
*
|
2008-02-22 |
2015-08-18 |
Allergan, Inc. |
Sustained release poloxamer containing pharmaceutical compositions
|
|
US8617571B2
(en)
*
|
2008-04-03 |
2013-12-31 |
Allergan, Inc. |
Suture line administration technique using botulinum toxin
|
|
KR20090120222A
(ko)
*
|
2008-05-19 |
2009-11-24 |
(주)메디톡스 |
식물 유래 성분 함유 배지 및 가요성 폐쇄 용기를 이용하여클로스트리디움 보툴리눔 독소를 생산하는 방법
|
|
US8535276B2
(en)
*
|
2008-06-26 |
2013-09-17 |
Bellanovus Development Company Llc |
Syringe-attached topical anesthetic dispenser
|
|
WO2010096134A1
(en)
*
|
2008-12-04 |
2010-08-26 |
Botulinum Toxin Research Associates, Inc. |
Extended length botulinum toxin formulation for human or mammalian use
|
|
KR20110106346A
(ko)
|
2008-12-10 |
2011-09-28 |
알러간, 인코포레이티드 |
클로스트리디움 독소 약제학적 조성물
|
|
HUE037595T2
(hu)
*
|
2008-12-31 |
2018-09-28 |
Revance Therapeutics Inc |
Injektálható botulinum toxin készítmények
|
|
CA2749034C
(en)
|
2009-01-07 |
2019-01-15 |
Robert John Petrella |
Treatment of soft tissue injury using hyaluronic acid and botulinum toxin
|
|
EP2248518B1
(en)
*
|
2009-04-17 |
2013-01-16 |
Merz Pharma GmbH & Co. KGaA |
Formulation for stabilizing proteins, peptides or mixtures thereof.
|
|
CN104324378A
(zh)
|
2009-05-29 |
2015-02-04 |
盖尔德马研究及发展公司 |
用于减少注射引起的皮肤反应的肾上腺素能受体激动剂和填充剂的可注射组合物
|
|
MX366344B
(es)
*
|
2009-06-25 |
2019-07-05 |
Revance Therapeutics Inc |
Formulaciones de toxina botulinica libres de albumina.
|
|
CN102470096B
(zh)
*
|
2009-06-30 |
2013-12-18 |
株式会社爱茉莉太平洋 |
一种含有覆盆子提取物的改善皮肤皱纹用化妆品组合物
|
|
US8129139B2
(en)
*
|
2009-07-13 |
2012-03-06 |
Allergan, Inc. |
Process for obtaining botulinum neurotoxin
|
|
HRP20181869T1
(hr)
|
2009-10-21 |
2019-01-11 |
Revance Therapeutics, Inc. |
Metode i sustavi za pročišćavanje nekompleksiranog botulinskog neurotoksina
|
|
AU2010313529A1
(en)
*
|
2009-10-30 |
2012-04-12 |
Duoject Medical Systems, Inc. |
Device and method for topical application of therapeutics or cosmetic compositions
|
|
WO2011075623A1
(en)
*
|
2009-12-18 |
2011-06-23 |
Latitude Pharmaceuticals, Inc. |
One - phase gel compos ition compri s ing phos pholi pids
|
|
US8940308B2
(en)
*
|
2010-03-30 |
2015-01-27 |
Allergan, Inc. |
Methods for treating depression
|
|
WO2012048854A2
(en)
*
|
2010-10-12 |
2012-04-19 |
Merz Pharma Gmbh & Co. Kgaa |
Formulation suitable for stabilizing proteins, which is free of mammalian excipients
|
|
ES2636680T5
(es)
*
|
2011-03-31 |
2023-10-31 |
Medy Tox Inc |
Preparación liofilizada de toxina botulínica
|
|
KR20130022923A
(ko)
*
|
2011-08-26 |
2013-03-07 |
삼성전자주식회사 |
가상 시점 합성 예측을 이용한 부호화/복호화 장치 및 부호화/복호화 방법
|
|
PT3130347T
(pt)
*
|
2011-12-30 |
2019-12-10 |
Halozyme Inc |
Variantes de polipéptidos de ph20, suas formulações e utilizações
|
|
AU2013243954A1
(en)
*
|
2012-04-02 |
2014-10-30 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
|
US9480731B2
(en)
*
|
2013-12-12 |
2016-11-01 |
Medy-Tox, Inc. |
Long lasting effect of new botulinum toxin formulations
|
|
WO2015140943A1
(ja)
|
2014-03-18 |
2015-09-24 |
日立金属株式会社 |
導電性樹脂組成物及び感圧センサ
|
|
US9579502B2
(en)
*
|
2014-04-19 |
2017-02-28 |
Medtronic, Inc. |
Implantable medical leads, systems, and related methods for creating a high impedance within a conduction path in the presence of a magnetic field of a given strength
|
|
JP7120765B2
(ja)
*
|
2015-11-25 |
2022-08-17 |
レゴケム バイオサイエンシズ， インク． |
ペプチド基を含む複合体及びそれに関連する方法
|
|
TWI777955B
(zh)
|
2016-05-27 |
2022-09-21 |
英商益普生生物製藥有限公司 |
神經毒素調配物
|
|
WO2018038301A1
(en)
|
2016-08-26 |
2018-03-01 |
Hugel Inc. |
Stabilized liquid formulation of botulinum toxin and preparation method thereof
|
|
KR102463881B1
(ko)
*
|
2016-10-04 |
2022-11-07 |
(주)메디톡스 |
보툴리눔 독소 함유 용액으로부터 보툴리눔 독소를 분리하는 방법
|
|
KR102088104B1
(ko)
*
|
2018-06-29 |
2020-03-11 |
호서대학교 산학협력단 |
개망초 꽃 에센셜 오일을 포함하는 신경 근육 관련 질환 예방 및 치료용 조성물
|
|
JP2022500426A
(ja)
*
|
2018-09-13 |
2022-01-04 |
アラーガン、インコーポレイテッドAllergan, Incorporated |
クロストリジウム毒素−ヒアルロン酸組成物
|
|
KR101968873B1
(ko)
*
|
2018-09-21 |
2019-04-29 |
아이큐어 주식회사 |
세포 침투 효과가 우수한 보툴리늄 유래 펩타이드를 포함하는 화장료 조성물
|
|
UY38744A
(es)
|
2019-06-07 |
2020-12-31 |
Nestle Skin Health S A |
Tratamiento de líneas glabelares y líneas cantales laterales de moderadas a muy graves
|