JP2016539131A5 - - Google Patents
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- Publication number
- JP2016539131A5 JP2016539131A5 JP2016535210A JP2016535210A JP2016539131A5 JP 2016539131 A5 JP2016539131 A5 JP 2016539131A5 JP 2016535210 A JP2016535210 A JP 2016535210A JP 2016535210 A JP2016535210 A JP 2016535210A JP 2016539131 A5 JP2016539131 A5 JP 2016539131A5
- Authority
- JP
- Japan
- Prior art keywords
- salt
- arachidylamide
- cholan
- dihydroxy
- amine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361911478P | 2013-12-04 | 2013-12-04 | |
| US61/911,478 | 2013-12-04 | ||
| PCT/IL2014/051052 WO2015083164A1 (en) | 2013-12-04 | 2014-12-04 | Aramchol salts |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020040825A Division JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539131A JP2016539131A (ja) | 2016-12-15 |
| JP2016539131A5 true JP2016539131A5 (enExample) | 2018-01-18 |
| JP6675310B2 JP6675310B2 (ja) | 2020-04-01 |
Family
ID=53272986
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535210A Active JP6675310B2 (ja) | 2013-12-04 | 2014-12-04 | アラムコール塩 |
| JP2020040825A Pending JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020040825A Pending JP2020111584A (ja) | 2013-12-04 | 2020-03-10 | アラムコール塩 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20160304553A1 (enExample) |
| EP (1) | EP3077047B1 (enExample) |
| JP (2) | JP6675310B2 (enExample) |
| KR (1) | KR102320191B1 (enExample) |
| CN (2) | CN110437298A (enExample) |
| AU (2) | AU2014358668B2 (enExample) |
| BR (1) | BR112016012465B1 (enExample) |
| CA (1) | CA2930232C (enExample) |
| CY (1) | CY1121736T1 (enExample) |
| DK (1) | DK3077047T3 (enExample) |
| ES (1) | ES2732845T3 (enExample) |
| HR (1) | HRP20191023T1 (enExample) |
| HU (1) | HUE045209T2 (enExample) |
| LT (1) | LT3077047T (enExample) |
| PL (1) | PL3077047T3 (enExample) |
| PT (1) | PT3077047T (enExample) |
| RS (1) | RS59067B1 (enExample) |
| SI (1) | SI3077047T1 (enExample) |
| SM (1) | SMT201900363T1 (enExample) |
| TR (1) | TR201909447T4 (enExample) |
| WO (1) | WO2015083164A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL227890A0 (en) * | 2013-08-08 | 2014-01-30 | Galderm Therapeutics Ltd | Antiaging compounds containing bile acid and fatty acid conjugates |
| WO2016199137A1 (en) | 2015-06-10 | 2016-12-15 | Galmed Research And Development Ltd. | Low dose compositions of aramchol salts |
| HUE045209T2 (hu) * | 2013-12-04 | 2019-12-30 | Galmed Res & Development Ltd | Aramchol-sók |
| NZ739679A (en) * | 2015-07-12 | 2022-02-25 | Cfso Gmbh | Cholecalciferol sulfate salts and their use for the treatment of vitamin d deficiency |
| WO2017017677A1 (en) * | 2015-07-27 | 2017-02-02 | Galmed Research And Development Ltd. | Combination treatment for liver disease |
| IL243707A0 (en) | 2016-01-20 | 2016-05-01 | Galmed Res And Dev Ltd | Treatment to regulate the microbiota in the intestine |
| FR3050112B1 (fr) | 2016-04-15 | 2020-09-04 | Soc Civ Immobiliere Gecinq | Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques |
| US10588880B2 (en) * | 2016-09-28 | 2020-03-17 | Eiger Biopharmaceuticals, Inc. | Methods and pharmaceutical compositions for the treatment of non-alcoholic steatohepatitis |
| MA46786A (fr) * | 2016-11-10 | 2019-09-18 | Galmed Res And Development Ltd | Inhibition de la fibrose chez des patients atteints d'une stéatose hépatique non alcoolique |
| US11197870B2 (en) | 2016-11-10 | 2021-12-14 | Galmed Research And Development Ltd | Treatment for hepatic fibrosis |
| WO2018223836A1 (zh) * | 2017-06-07 | 2018-12-13 | 苏州科睿思制药有限公司 | 一种脂肪酸胆汁酸偶合物的晶型及其制备方法和用途 |
| IL273078B2 (en) | 2017-09-13 | 2025-06-01 | Emmyon Inc | Ursolic acid morpholine and diethanolamine salts |
| WO2019125913A1 (en) * | 2017-12-20 | 2019-06-27 | Michael Guarnieri | Nutritional bolus for animals |
| JP6612004B1 (ja) * | 2018-07-31 | 2019-11-27 | 株式会社親広産業 | グルコース消費促進剤および解糖系促進剤 |
| WO2020026471A1 (ja) * | 2018-07-31 | 2020-02-06 | 株式会社親広産業 | グルコース消費促進剤および解糖系促進剤 |
| KR20240032679A (ko) * | 2022-09-02 | 2024-03-12 | 주식회사 렉스팜텍 | 신규 벤포티아민 콜린염 |
| US12090151B1 (en) | 2023-05-12 | 2024-09-17 | Michael Guarnieri | Injectable sustained release buprenorphine formulation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2252863A (en) * | 1941-02-03 | 1941-08-19 | Searle & Co | Quaternary ammonium salts |
| GB1532413A (en) * | 1974-12-23 | 1978-11-15 | Union International Co Ltd | Chenodeoxycholic acid |
| IL123998A (en) * | 1998-04-08 | 2004-09-27 | Galmed Int Ltd | Conjugates of bile salts and pharmaceutical preparations containing them |
| IL142650A (en) * | 1998-04-08 | 2007-06-03 | Galmed Int Ltd | Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes |
| US7098196B1 (en) * | 1999-10-13 | 2006-08-29 | Johns Hopkins University School Of Medicine | Regulators of the hedgehog pathway, compositions and uses related thereto |
| US8975246B2 (en) * | 2001-04-17 | 2015-03-10 | Galmed Research And Development Ltd. | Bile acid or bile salt fatty acid conjugates |
| EP1742631A4 (en) * | 2004-04-28 | 2009-11-11 | Merck & Co Inc | FLUORATED 4-AZASTEROIDS AS ANDROGEN RECEPTOR MODULATORS |
| ITMI20061735A1 (it) * | 2006-09-12 | 2008-03-13 | Dipharma Spa | Procedimento per la preparazione di acidi colanici |
| DE102007032507A1 (de) * | 2007-07-12 | 2009-04-02 | Merck Patent Gmbh | Pyridazinonderivate |
| WO2010086864A1 (en) * | 2009-02-02 | 2010-08-05 | Galmed International Ltd. | Methods and compositions for treating alzheimer's disease |
| CN102656181A (zh) * | 2009-12-15 | 2012-09-05 | 明治制果药业株式会社 | 三萜衍生物及用于预防或治疗c型慢性肝炎的药剂 |
| CN102115486B (zh) * | 2009-12-30 | 2015-06-03 | 上海特化医药科技有限公司 | 一种3-β-花生酰胺基-7α,12α,5β-胆烷-24-羧酸的制备方法 |
| BR112012018913A2 (pt) * | 2010-01-28 | 2017-06-20 | Merck Sharp & Dohme | "composição farmacêutica, e, uso da composição" |
| PT2531501E (pt) * | 2010-02-03 | 2014-02-17 | Takeda Pharmaceutical | Inibidores da cinase de regulação do sinal de apoptose 1 |
| HRP20180970T1 (hr) * | 2010-12-07 | 2018-08-10 | Amira Pharmaceuticals, Inc. | Policiklični lpa1 antagonist i njegove primjene |
| HUE045209T2 (hu) * | 2013-12-04 | 2019-12-30 | Galmed Res & Development Ltd | Aramchol-sók |
-
2014
- 2014-12-04 HU HUE14868582A patent/HUE045209T2/hu unknown
- 2014-12-04 EP EP14868582.9A patent/EP3077047B1/en active Active
- 2014-12-04 LT LTEP14868582.9T patent/LT3077047T/lt unknown
- 2014-12-04 AU AU2014358668A patent/AU2014358668B2/en active Active
- 2014-12-04 CN CN201910687060.8A patent/CN110437298A/zh active Pending
- 2014-12-04 RS RS20190787A patent/RS59067B1/sr unknown
- 2014-12-04 JP JP2016535210A patent/JP6675310B2/ja active Active
- 2014-12-04 CA CA2930232A patent/CA2930232C/en active Active
- 2014-12-04 TR TR2019/09447T patent/TR201909447T4/tr unknown
- 2014-12-04 US US15/100,993 patent/US20160304553A1/en not_active Abandoned
- 2014-12-04 PT PT14868582T patent/PT3077047T/pt unknown
- 2014-12-04 BR BR112016012465-0A patent/BR112016012465B1/pt active IP Right Grant
- 2014-12-04 CN CN201480064913.8A patent/CN105848718B/zh active Active
- 2014-12-04 PL PL14868582T patent/PL3077047T3/pl unknown
- 2014-12-04 WO PCT/IL2014/051052 patent/WO2015083164A1/en not_active Ceased
- 2014-12-04 SI SI201431253T patent/SI3077047T1/sl unknown
- 2014-12-04 HR HRP20191023TT patent/HRP20191023T1/hr unknown
- 2014-12-04 DK DK14868582.9T patent/DK3077047T3/da active
- 2014-12-04 ES ES14868582T patent/ES2732845T3/es active Active
- 2014-12-04 SM SM20190363T patent/SMT201900363T1/it unknown
- 2014-12-04 KR KR1020167017460A patent/KR102320191B1/ko active Active
-
2019
- 2019-07-01 CY CY20191100688T patent/CY1121736T1/el unknown
- 2019-12-06 AU AU2019275638A patent/AU2019275638B2/en active Active
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2020
- 2020-03-10 JP JP2020040825A patent/JP2020111584A/ja active Pending