JP2016539083A5 - - Google Patents
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- Publication number
- JP2016539083A5 JP2016539083A5 JP2016519326A JP2016519326A JP2016539083A5 JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5 JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016519326 A JP2016519326 A JP 2016519326A JP 2016539083 A5 JP2016539083 A5 JP 2016539083A5
- Authority
- JP
- Japan
- Prior art keywords
- αvβ6
- her2
- inhibitor
- binding agent
- targeted binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361885302P | 2013-10-01 | 2013-10-01 | |
| US61/885,302 | 2013-10-01 | ||
| PCT/EP2014/071028 WO2015049280A1 (en) | 2013-10-01 | 2014-10-01 | Methods of treating and diagnosing alpha-v-beta-6 overexpressing cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019052035A Division JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539083A JP2016539083A (ja) | 2016-12-15 |
| JP2016539083A5 true JP2016539083A5 (https=) | 2017-11-09 |
| JP6527508B2 JP6527508B2 (ja) | 2019-06-05 |
Family
ID=51655742
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016519326A Active JP6527508B2 (ja) | 2013-10-01 | 2014-10-01 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
| JP2019052035A Pending JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019052035A Pending JP2019142876A (ja) | 2013-10-01 | 2019-03-20 | αＶβ６を過剰発現する癌を治療及び診断する方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20160319032A1 (https=) |
| EP (1) | EP3052523B1 (https=) |
| JP (2) | JP6527508B2 (https=) |
| CN (1) | CN106232625B (https=) |
| AU (1) | AU2014331118B2 (https=) |
| CA (1) | CA2925057A1 (https=) |
| WO (1) | WO2015049280A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015109391A1 (en) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| AU2016366515A1 (en) * | 2015-12-11 | 2018-06-21 | Ruprecht-Karls-Universität Heidelberg | Combined preparations of PKM2 modulators and HMGB1 |
| AU2017269335B2 (en) | 2016-05-26 | 2021-07-01 | Recurium Ip Holdings, Llc | EGFR inhibitor compounds |
| IL263272B2 (en) * | 2016-06-14 | 2025-07-01 | Merck Sharp & Dohme | Antibodies to coagulation factor xi |
| ES2928773T3 (es) | 2017-01-17 | 2022-11-22 | Heparegenix Gmbh | Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos |
| CN106950371B (zh) * | 2017-02-17 | 2019-03-08 | 张灏 | Pd-l1、cdk5和ctla4中的至少一种在制备肿瘤诊断试剂盒中的用途 |
| EP4353318A3 (en) * | 2017-03-31 | 2024-07-17 | The Regents of the University of California | Compositions and methods for targeting and killing alpha-v beta-3-positive cancer stem cells (cscs) and treating drug resistant cancers |
| CN109265551B (zh) * | 2018-09-25 | 2020-09-15 | 华东师范大学 | Cd38抗体、嵌合抗原受体和药物 |
| WO2020092736A1 (en) | 2018-10-31 | 2020-05-07 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| US12264189B2 (en) | 2018-10-31 | 2025-04-01 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| CA3143952A1 (en) * | 2019-02-22 | 2020-08-27 | Candel Therapeutics, Inc. | Gmci and ddri combination therapy for treating cancer |
| KR20220110231A (ko) * | 2019-12-05 | 2022-08-05 | 씨젠 인크. | 항-αvβ6 항체 및 항체-약물 접합체 |
| US11579085B2 (en) * | 2020-07-17 | 2023-02-14 | Robert Bosch Gmbh | Sensing devices |
| CN114195893A (zh) * | 2020-09-17 | 2022-03-18 | 百奥泰生物制药股份有限公司 | 抗整联蛋白抗体或抗原结合片段及其应用 |
| CN118440187A (zh) * | 2023-01-05 | 2024-08-06 | 郴州市第一人民医院 | 一种抗SARS-like冠状病毒和/或新冠突变株的广谱抗体及其应用 |
| CN117603348B (zh) * | 2023-11-24 | 2024-08-09 | 优睿赛思(武汉)生物科技有限公司 | 抗新型冠状病毒s蛋白的全人源化抗体及其应用 |
| EP4595981A1 (en) * | 2024-02-01 | 2025-08-06 | Jack Elands | Antibody-drug conjugates comprising an anti-integrin v 6 binding antibody |
| WO2025163120A1 (en) | 2024-02-01 | 2025-08-07 | Adcytherix Sas | ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-INTEGRIN ΑVβ6 BINDING ANTIBODY |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1646160A (zh) * | 2002-03-13 | 2005-07-27 | 拜奥根Idec马萨诸塞公司 | 抗αvβ6抗体 |
| CN102875681A (zh) * | 2005-07-08 | 2013-01-16 | 拜奥根Idec马萨诸塞公司 | 抗-αvβ6抗体及其用途 |
| TW200815474A (en) * | 2006-08-03 | 2008-04-01 | Astrazeneca Ab | Antibodies alphaVbeta6 and uses thereof |
| CN104220094A (zh) * | 2012-02-17 | 2014-12-17 | 西雅图基因公司 | 针对整联蛋白αvβ6的抗体和使用该抗体治疗癌症 |
-
2014
- 2014-10-01 AU AU2014331118A patent/AU2014331118B2/en active Active
- 2014-10-01 JP JP2016519326A patent/JP6527508B2/ja active Active
- 2014-10-01 EP EP14777632.2A patent/EP3052523B1/en not_active Not-in-force
- 2014-10-01 US US15/026,350 patent/US20160319032A1/en not_active Abandoned
- 2014-10-01 CN CN201480065738.4A patent/CN106232625B/zh active Active
- 2014-10-01 WO PCT/EP2014/071028 patent/WO2015049280A1/en not_active Ceased
- 2014-10-01 CA CA2925057A patent/CA2925057A1/en not_active Abandoned
-
2018
- 2018-11-06 US US16/181,907 patent/US20190389967A1/en not_active Abandoned
-
2019
- 2019-03-20 JP JP2019052035A patent/JP2019142876A/ja active Pending
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