JP2016536993A5 - - Google Patents

Download PDF

Info

Publication number
JP2016536993A5
JP2016536993A5 JP2016530177A JP2016530177A JP2016536993A5 JP 2016536993 A5 JP2016536993 A5 JP 2016536993A5 JP 2016530177 A JP2016530177 A JP 2016530177A JP 2016530177 A JP2016530177 A JP 2016530177A JP 2016536993 A5 JP2016536993 A5 JP 2016536993A5
Authority
JP
Japan
Prior art keywords
coli
strain
modified
mutation
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016530177A
Other languages
English (en)
Japanese (ja)
Other versions
JP6545676B2 (ja
JP2016536993A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/065545 external-priority patent/WO2015073720A1/en
Publication of JP2016536993A publication Critical patent/JP2016536993A/ja
Publication of JP2016536993A5 publication Critical patent/JP2016536993A5/ja
Application granted granted Critical
Publication of JP6545676B2 publication Critical patent/JP6545676B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016530177A 2013-11-14 2014-11-13 改善された代謝能力を有する細菌 Active JP6545676B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361904298P 2013-11-14 2013-11-14
US61/904,298 2013-11-14
PCT/US2014/065545 WO2015073720A1 (en) 2013-11-14 2014-11-13 Bacteria with improved metabolic capacity

Publications (3)

Publication Number Publication Date
JP2016536993A JP2016536993A (ja) 2016-12-01
JP2016536993A5 true JP2016536993A5 (enExample) 2017-12-28
JP6545676B2 JP6545676B2 (ja) 2019-07-17

Family

ID=53058029

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016530177A Active JP6545676B2 (ja) 2013-11-14 2014-11-13 改善された代謝能力を有する細菌

Country Status (4)

Country Link
US (2) US9902965B2 (enExample)
EP (1) EP3068887B1 (enExample)
JP (1) JP6545676B2 (enExample)
WO (1) WO2015073720A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121826088A (zh) * 2015-04-02 2026-04-10 斯卡拉布基因组有限责任公司 用于基因组减少的细菌的延长连续流发酵的材料和方法
IL316539B1 (en) 2016-03-15 2026-05-01 Rnaissance Ag Llc Methods and compositions for the enhanced production of double-stranded RNA
AU2018329671B2 (en) 2017-09-05 2023-12-07 Scarab Genomics, Llc Methods and compositions for improved expression of recombinant proteins
CN108587992B (zh) * 2018-04-10 2022-03-15 安徽大学 一种高效分泌表达抗VEGF-Fab抗体片段的高产菌株及其构建方法
CA3142362A1 (en) * 2019-05-30 2020-12-03 Rnaissance Ag Llc Improved methods and compositions for increased double stranded rna production
US20230167467A1 (en) * 2020-04-15 2023-06-01 University of Alaska Anchorage Methods and compositions for the production of isobutene
US12168679B2 (en) 2020-11-10 2024-12-17 Northwestern University Modified bacteria for enhanced bioproduction and methods of using the same
AU2024211834A1 (en) 2023-01-25 2025-08-07 Novel Biotechnology Usa Inc. Expression system for product manufacturing

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578464A (en) 1989-10-31 1996-11-26 Schering Corporation E. coli secretory strains
US5747662A (en) 1995-03-01 1998-05-05 Genentech, Inc. Methods and compositions for secretion of heterologous polypeptides
US6022952A (en) 1998-04-01 2000-02-08 University Of Alberta Compositions and methods for protein secretion
US8119365B2 (en) 2002-01-23 2012-02-21 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US6989265B2 (en) 2002-01-23 2006-01-24 Wisconsin Alumni Research Foundation Bacteria with reduced genome
US8039243B2 (en) 2002-01-23 2011-10-18 Wisconsin Alumni Research Foundation Insertion sequence-free bacteria
US7303906B2 (en) 2002-09-06 2007-12-04 Wisconsin Alumni Research Foundation Competent bacteria
US7300776B2 (en) * 2004-04-26 2007-11-27 Ajinomoto Co., Inc. L-amino acid-producing bacterium and a method for producing L-amino acid
BRPI0517908A (pt) 2004-11-26 2008-10-14 Kyowa Hakko Kogyo Kk cepa mutante de e. coli, e, método para produzir uma substáncia útil
CA2626900C (en) 2005-08-20 2013-07-23 Scarab Genomics, Llc Reduced genome e. coli
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc L−アミノ酸を生産する微生物及びl−アミノ酸の製造法
WO2007140816A1 (en) * 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
HUE025524T2 (en) * 2008-02-22 2016-05-30 Scarab Genomics Llc Preparations and Methods for Biosynthesis of Amino Acid
EP2298880A4 (en) 2008-03-18 2012-02-08 Kyowa Hakko Kirin Co Ltd INDUSTRIALLY USEFUL MICROORGANISM
CA2808140A1 (en) * 2010-08-27 2012-03-01 Metabolic Explorer Improved glycolic acid fermentative production with a modified microorganism
AU2012325917B2 (en) 2011-10-20 2018-04-12 Scarab Genomics, Llc Reduced genome bacteria with improved genetic stability
WO2015134402A1 (en) * 2014-03-03 2015-09-11 Scarab Genomics, Llc Enhanced production of recombinant crm197 in e. coli

Similar Documents

Publication Publication Date Title
MX2022003994A (es) Produccion de oligosacaridos de leche humana en huespedes microbianos con importacion/exportacion dise?ada.
CY1123815T1 (el) Υποκατεστημενες ινδαζολες, διαδικασια για την παρασκευη τους, φαρμακευτικα παρασκευασματα, τα οποια τις περιεχουν, καθως και η χρηση τους για την παρασκευη φαρμακευτικων μεσων
Piñero-Lambea et al. Mycoplasma pneumoniae genome editing based on oligo recombineering and Cas9-mediated counterselection
CY1120493T1 (el) Πρωτεϊνη συντηξης που περιλαμβανει ιντερλευκινη 4 και ιντερλευκινη 10
ZA202001294B (en) Multispecific antibody
GB2574769A (en) RNA Targeting of mutations via suppressor tRNAs and deaminases
BR112012033699A2 (pt) polipeptídeo tendo atividade beta-glicosidase e seus usos
JP2014530625A5 (enExample)
EA201691990A1 (ru) Получение библиотек вариантов белков, экспрессированных в эукариотических клетках, и применение их для отбора связывающих молекул
JP2017169582A5 (enExample)
MX2020002674A (es) Produccion de xilitol a partir de glucosa mediante una cepa recombinante.
MX359953B (es) Ácido nucleico que comprende o que codifica un tallo-rizo de histona y una secuencia poli (a) o una señal de poliadenilación para incrementar la expresión de una proteína terapéutica codificada.
EA201791343A1 (ru) Композиции и способы для конструирования вирусного генома in vitro
JP2014000092A5 (enExample)
Obuchowski et al. Duplicate divergence of two bacterial small heat shock proteins reduces the demand for Hsp70 in refolding of substrates
HK1207111A1 (en) Methods and compositions for controlling gene expression by rna processing
MX357484B (es) Cepa con deficit de amilasa.
MX346663B (es) Lineas de celulas de bajo nivel de fucosa y usos de las mismas.
MY176331A (en) Carbohydrate degrading polypeptide and uses thereof
MX2022015112A (es) Inductor haploide.
MY185246A (en) Optimized method for producing methacrolein
MX2024013590A (es) Adnc del antagonista del receptor de interleucina-1
WO2015199387A3 (ko) 가용성 단백질 발현량 및 활성이 증대된 헬리코박터 파일로리 유래 α-1,3 푸코실 전달효소의 유전자와 단백질 및 α-1,3 푸코실올리고당 생산에의 응용
BR112016020517A2 (pt) método de produção de lipídeo através da utilização de ss-cetoacil-acp sintase
MX2015015274A (es) Ruta de ácido organico novedosa.