JP2016532643A5 - - Google Patents
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- Publication number
- JP2016532643A5 JP2016532643A5 JP2016520591A JP2016520591A JP2016532643A5 JP 2016532643 A5 JP2016532643 A5 JP 2016532643A5 JP 2016520591 A JP2016520591 A JP 2016520591A JP 2016520591 A JP2016520591 A JP 2016520591A JP 2016532643 A5 JP2016532643 A5 JP 2016532643A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery device
- transdermal delivery
- acid
- dexmedetomidine
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361887871P | 2013-10-07 | 2013-10-07 | |
| US61/887,871 | 2013-10-07 | ||
| PCT/US2014/059058 WO2015054063A1 (en) | 2013-10-07 | 2014-10-03 | Methods and compositions for treating withdrawal syndromes using non-sedative dexmedetomidine transdermal compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016532643A JP2016532643A (ja) | 2016-10-20 |
| JP2016532643A5 true JP2016532643A5 (https=) | 2017-09-28 |
| JP6231670B2 JP6231670B2 (ja) | 2017-11-15 |
Family
ID=52777130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016520591A Active JP6231670B2 (ja) | 2013-10-07 | 2014-10-03 | 非鎮静性デクスメデトミジン経皮組成物を用いる、離脱症候群の治療法及び組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20150098983A1 (https=) |
| EP (1) | EP3054934B1 (https=) |
| JP (1) | JP6231670B2 (https=) |
| KR (2) | KR101881791B1 (https=) |
| CN (1) | CN105682650B (https=) |
| CA (1) | CA2924190C (https=) |
| ES (1) | ES2983565T3 (https=) |
| FI (1) | FI3054934T3 (https=) |
| RU (1) | RU2648817C2 (https=) |
| TW (1) | TWI624278B (https=) |
| WO (1) | WO2015054063A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2924233C (en) * | 2013-10-07 | 2018-10-23 | Teikoku Pharma Usa, Inc. | Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions |
| GB201600918D0 (en) * | 2016-01-18 | 2016-03-02 | Buzzz Pharmaceuticals Ltd | Transdermal patch |
| BR112019006955A2 (pt) | 2016-10-31 | 2019-07-02 | Teikoku Pharma Usa Inc | métodos de controle da dor usando dispositivos de distribuição transdérmica de dexmedetomidina |
| IL267689B2 (en) | 2016-12-31 | 2025-05-01 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| CN111447927A (zh) * | 2017-12-08 | 2020-07-24 | 帝国制药美国公司 | 纳洛酮经皮给药装置及其使用方法 |
| EP3813828A4 (en) * | 2018-06-27 | 2022-03-30 | Bioxcel Therapeutics, Inc. | METHOD OF TREATMENT OF AGITATION WITH DEXMEDETOMIDIN HYDROCHLORIDE |
| BR112020026672A2 (pt) | 2018-06-27 | 2021-03-30 | Bioxcel Therapeutics, Inc. | Formulações de filme contendo dexmedetomidina e métodos para produzi-las |
| CN112996491A (zh) * | 2018-10-15 | 2021-06-18 | 阿姆农·瓦尔迪 | 缓释大麻素及其产品 |
| WO2020084065A1 (en) * | 2018-10-24 | 2020-04-30 | Saniona A/S | Transdermal tropane compositions and methods for using the same |
| CA3135552C (en) * | 2019-04-17 | 2023-09-26 | Lts Lohmann Therapie-Systeme Ag | Ketamine containing transdermal therapeutic system comprising free hydroxyl groups |
| BR112022000992A2 (pt) * | 2019-07-19 | 2022-06-14 | Arx Llc | Regimes de tratamento de dexmedetomidina não sedantes |
| JP7495989B2 (ja) | 2020-02-14 | 2024-06-05 | テイコク ファーマ ユーエスエー インコーポレーテッド | 局所用ナロキソン組成物およびそれを使用するための方法 |
| US20240024289A1 (en) * | 2020-10-08 | 2024-01-25 | Bioxcel Therapeutics, Inc. | Treatment of bipolar disorders and psychosis using dexmedetomidine hydrochloride |
| JP2024502082A (ja) * | 2021-01-04 | 2024-01-17 | バイオエクセル セラピューティクス，インコーポレイテッド | デクスメデトミジン治療レジメン |
| CN115227638B (zh) * | 2022-07-19 | 2025-03-18 | 广州新济生物医药研究院有限公司 | 一种盐酸右美托咪定可溶性微针及其制备方法 |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| AU2024253436A1 (en) * | 2023-04-04 | 2025-11-13 | Board Of Regents, The University Of Texas System | Combinations including methocinnamox |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5217718A (en) * | 1989-08-18 | 1993-06-08 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| US5124157A (en) * | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| GB9111732D0 (en) * | 1991-05-31 | 1991-07-24 | Orion Yhtymae Oy | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
| CN1188189C (zh) * | 1995-06-07 | 2005-02-09 | 奥瑟－麦内尔制药公司 | 基质层含有17－脱乙酰基诺孕酯的经皮贴片及基质的用途 |
| GB9521680D0 (en) * | 1995-10-23 | 1996-01-03 | Orion Yhtymo Oy | New use of imidazole derivatives |
| US5891868A (en) * | 1997-11-21 | 1999-04-06 | Kaiser Foundation Health Plan, Inc. | Methods for treating postmenopausal women using ultra-low doses of estrogen |
| MXPA01003310A (es) * | 1998-10-02 | 2003-05-15 | 3M Innovative Properties Co | Sistema de suministro de farmaco originados en mucosa y aplicaciones animales. |
| US20030170195A1 (en) * | 2000-01-10 | 2003-09-11 | Noven Pharmaceuticals, Inc. | Compositions and methods for drug delivery |
| TWI341735B (en) * | 2003-07-31 | 2011-05-11 | Hisamitsu Pharmaceutical Co | Adhesive preparations |
| EP2062575B1 (en) * | 2006-09-11 | 2012-02-15 | Sekisui Chemical Co., Ltd. | Adhesive preparation comprising desglymidodrine |
| EP2286814B1 (en) * | 2008-05-15 | 2013-10-16 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal preparation containing palonosetron |
| US20130072532A1 (en) | 2010-01-08 | 2013-03-21 | Recro Pharma, Inc. | Topical transdermal dexmedetomidine compositions and methods of use thereof |
| AU2011331511C1 (en) * | 2010-11-17 | 2018-01-18 | Hexal Ag | Transdermal therapeutic system comprising buprenorphine |
| WO2013072763A2 (en) * | 2011-11-16 | 2013-05-23 | Nometics Inc. | Non-sensitizing transdermal clonidine patch |
| WO2013090278A2 (en) * | 2011-12-11 | 2013-06-20 | Recro Pharma, Inc. | Intranasal dexmedetomidine compositions and methods of use thereof |
| US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
| HUE035312T2 (en) * | 2012-01-31 | 2018-05-02 | Gruenenthal Gmbh | Pharmaceutical patch (1R, 4R) -6'-fluoro-N, N-dimethyl-4-phenyl-4 ', 9'-dihydro-3'H-spiro [cyclohexane-1,1'-pyrano [3,4- b] for transdermal administration of indole] -4-amine |
-
2014
- 2014-10-03 KR KR1020187004780A patent/KR101881791B1/ko active Active
- 2014-10-03 TW TW103134526A patent/TWI624278B/zh active
- 2014-10-03 ES ES14852359T patent/ES2983565T3/es active Active
- 2014-10-03 EP EP14852359.0A patent/EP3054934B1/en active Active
- 2014-10-03 JP JP2016520591A patent/JP6231670B2/ja active Active
- 2014-10-03 FI FIEP14852359.0T patent/FI3054934T3/fi active
- 2014-10-03 US US14/505,943 patent/US20150098983A1/en not_active Abandoned
- 2014-10-03 WO PCT/US2014/059058 patent/WO2015054063A1/en not_active Ceased
- 2014-10-03 RU RU2016109632A patent/RU2648817C2/ru active
- 2014-10-03 KR KR1020167010340A patent/KR20160055934A/ko not_active Ceased
- 2014-10-03 CA CA2924190A patent/CA2924190C/en active Active
- 2014-10-03 CN CN201480058703.8A patent/CN105682650B/zh active Active
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