JP2016531927A - 癌治療でのパパイヤモザイクウイルス及びウイルス様粒子 - Google Patents
癌治療でのパパイヤモザイクウイルス及びウイルス様粒子 Download PDFInfo
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- JP2016531927A JP2016531927A JP2016543278A JP2016543278A JP2016531927A JP 2016531927 A JP2016531927 A JP 2016531927A JP 2016543278 A JP2016543278 A JP 2016543278A JP 2016543278 A JP2016543278 A JP 2016543278A JP 2016531927 A JP2016531927 A JP 2016531927A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- A—HUMAN NECESSITIES
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- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A61K2239/57—Skin; melanoma
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A61K35/66—Microorganisms or materials therefrom
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals
- A61K9/5184—Virus capsids or envelopes enclosing drugs
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- C12N2770/40011—Tymoviridae
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- C12N2770/40011—Tymoviridae
- C12N2770/40023—Virus like particles [VLP]
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/40011—Tymoviridae
- C12N2770/40033—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2770/00011—Details
- C12N2770/40011—Tymoviridae
- C12N2770/40034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/40011—Tymoviridae
- C12N2770/40041—Use of virus, viral particle or viral elements as a vector
- C12N2770/40042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361880156P | 2013-09-19 | 2013-09-19 | |
| US61/880,156 | 2013-09-19 | ||
| US201361886481P | 2013-10-03 | 2013-10-03 | |
| US61/886,481 | 2013-10-03 | ||
| PCT/CA2014/050908 WO2015039255A1 (en) | 2013-09-19 | 2014-09-19 | Papaya mosaic virus and virus-like particles in cancer therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016531927A true JP2016531927A (ja) | 2016-10-13 |
| JP2016531927A5 JP2016531927A5 (enExample) | 2017-10-26 |
Family
ID=52688058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016543278A Pending JP2016531927A (ja) | 2013-09-19 | 2014-09-19 | 癌治療でのパパイヤモザイクウイルス及びウイルス様粒子 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20160228541A1 (enExample) |
| EP (1) | EP3046565A4 (enExample) |
| JP (1) | JP2016531927A (enExample) |
| CN (1) | CN105899217A (enExample) |
| CA (1) | CA2924819A1 (enExample) |
| MX (1) | MX2016003653A (enExample) |
| WO (1) | WO2015039255A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2906260B1 (en) | 2012-10-09 | 2019-06-26 | Case Western Reserve University | Rod-shaped plant virus nanoparticles as imaging agent platforms |
| US11193111B2 (en) | 2013-01-17 | 2021-12-07 | Case Western Reserve University | Viral nanoparticle multimers |
| US9925281B2 (en) | 2014-08-05 | 2018-03-27 | Case Western Reserve University | Coated plant virus imaging agents |
| EP3215520B1 (en) | 2014-11-07 | 2022-01-05 | Case Western Reserve University | Cancer immunotherapy using virus particles |
| WO2017004123A1 (en) | 2015-06-29 | 2017-01-05 | Case Western Reserve University | Anticancer drug-containing plant virus particles |
| EP3322485B1 (en) | 2015-07-16 | 2020-07-01 | Case Western Reserve University | Plant virus particles for delivery of antimitotic agents |
| EP3487527A4 (en) | 2016-07-21 | 2020-03-11 | Case Western Reserve University | Plant virus or virus-like particle constructs |
| CA3042695A1 (en) | 2016-11-03 | 2018-05-11 | Case Western Reserve University | Melt processed viral nanoparticle constructs |
| US12433840B2 (en) | 2016-11-03 | 2025-10-07 | Case Western Reserve University | Melt processed viral nanoparticle constructs |
| US11590183B2 (en) | 2017-03-10 | 2023-02-28 | Case Western Reserve University | Cancer immunotherapy using virus particles |
| WO2018213587A1 (en) | 2017-05-17 | 2018-11-22 | Case Western Reserve University | Anticancer trail-targeted plant virus particles |
| US11739301B2 (en) | 2017-10-27 | 2023-08-29 | Case Western Reserve University | Tymovirus virus and virus-like particles as nanocarriers for imaging and therapeutic agents |
| US11390853B2 (en) | 2019-04-26 | 2022-07-19 | Case Western Reserve University | Freeze dried viral nanoparticle constructs |
| US11896676B2 (en) | 2019-08-07 | 2024-02-13 | Case Western Reserve University | Targeting cancer cells and tissue using filamentous plant virus particles |
| US11529430B2 (en) | 2019-12-20 | 2022-12-20 | Case Western Reserve University | Polydopamine decorated tobacco mosaic theranostic virus nanoparticles |
| US12203073B2 (en) | 2019-12-20 | 2025-01-21 | Case Western Reserve University | Plant viral RNA delivery nanoparticles and uses thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012155261A1 (en) * | 2011-05-13 | 2012-11-22 | Folia Biotech Inc. | Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1665528B (zh) * | 2002-07-05 | 2013-05-15 | 弗利亚生物技术公司 | 佐剂病毒颗粒 |
| US8101189B2 (en) * | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
-
2014
- 2014-09-19 WO PCT/CA2014/050908 patent/WO2015039255A1/en not_active Ceased
- 2014-09-19 CA CA2924819A patent/CA2924819A1/en not_active Abandoned
- 2014-09-19 JP JP2016543278A patent/JP2016531927A/ja active Pending
- 2014-09-19 US US15/022,907 patent/US20160228541A1/en not_active Abandoned
- 2014-09-19 EP EP14846668.3A patent/EP3046565A4/en not_active Withdrawn
- 2014-09-19 CN CN201480057495.XA patent/CN105899217A/zh active Pending
- 2014-09-19 MX MX2016003653A patent/MX2016003653A/es unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012155261A1 (en) * | 2011-05-13 | 2012-11-22 | Folia Biotech Inc. | Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response |
| WO2012155262A1 (en) * | 2011-05-13 | 2012-11-22 | Folia Biotech Inc. | Virus-like particles and process for preparing same |
Non-Patent Citations (3)
| Title |
|---|
| IMMUNOLOGY, vol. 124, JPN6018020133, 2007, pages 186 - 197, ISSN: 0003808407 * |
| NEW 薬理学(改訂第6版), JPN6018020130, 5 April 2011 (2011-04-05), pages 449, ISSN: 0003977781 * |
| VIROLOGY, vol. 199, JPN6016008091, 1994, pages 238 - 242, ISSN: 0003977782 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015039255A1 (en) | 2015-03-26 |
| CN105899217A (zh) | 2016-08-24 |
| MX2016003653A (es) | 2016-08-11 |
| CA2924819A1 (en) | 2015-03-26 |
| EP3046565A4 (en) | 2017-06-28 |
| US20160228541A1 (en) | 2016-08-11 |
| EP3046565A1 (en) | 2016-07-27 |
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