JP2016531878A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016531878A5 JP2016531878A5 JP2016518708A JP2016518708A JP2016531878A5 JP 2016531878 A5 JP2016531878 A5 JP 2016531878A5 JP 2016518708 A JP2016518708 A JP 2016518708A JP 2016518708 A JP2016518708 A JP 2016518708A JP 2016531878 A5 JP2016531878 A5 JP 2016531878A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- pain
- inflammation
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 206010061218 Inflammation Diseases 0.000 claims 5
- 208000002193 Pain Diseases 0.000 claims 5
- 230000004054 inflammatory process Effects 0.000 claims 5
- 201000004624 Dermatitis Diseases 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 claims 2
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims 1
- OLOSVFFOXWXCPF-UHFFFAOYSA-N 3-benzylsulfonylpropanenitrile Chemical compound N#CCCS(=O)(=O)CC1=CC=CC=C1 OLOSVFFOXWXCPF-UHFFFAOYSA-N 0.000 claims 1
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 1
- 206010006811 Bursitis Diseases 0.000 claims 1
- 206010008685 Chondritis Diseases 0.000 claims 1
- 208000034656 Contusions Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims 1
- 208000001640 Fibromyalgia Diseases 0.000 claims 1
- 201000005569 Gout Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 206010024453 Ligament sprain Diseases 0.000 claims 1
- 208000021642 Muscular disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010037779 Radiculopathy Diseases 0.000 claims 1
- 208000010040 Sprains and Strains Diseases 0.000 claims 1
- 235000019486 Sunflower oil Nutrition 0.000 claims 1
- 206010042674 Swelling Diseases 0.000 claims 1
- 208000000491 Tendinopathy Diseases 0.000 claims 1
- 208000023835 Tendon disease Diseases 0.000 claims 1
- 206010043255 Tendonitis Diseases 0.000 claims 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000010247 contact dermatitis Diseases 0.000 claims 1
- 230000009519 contusion Effects 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims 1
- QQQMUBLXDAFBRH-UHFFFAOYSA-N dodecyl 2-hydroxypropanoate Chemical compound CCCCCCCCCCCCOC(=O)C(C)O QQQMUBLXDAFBRH-UHFFFAOYSA-N 0.000 claims 1
- 239000003974 emollient agent Substances 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 210000003195 fascia Anatomy 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 210000001503 joint Anatomy 0.000 claims 1
- 150000003903 lactic acid esters Chemical class 0.000 claims 1
- 210000003041 ligament Anatomy 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 229960003921 octisalate Drugs 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 claims 1
- 229960001860 salicylate Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229940031439 squalene Drugs 0.000 claims 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims 1
- 239000002600 sunflower oil Substances 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 201000004415 tendinitis Diseases 0.000 claims 1
- 210000002435 tendon Anatomy 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical group CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361885428P | 2013-10-01 | 2013-10-01 | |
| US61/885,428 | 2013-10-01 | ||
| PCT/US2014/058347 WO2015050878A1 (en) | 2013-10-01 | 2014-09-30 | Pharmaceutical use of 3-benzylsulfonylpropionitrile |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016531878A JP2016531878A (ja) | 2016-10-13 |
| JP2016531878A5 true JP2016531878A5 (https=) | 2017-11-02 |
| JP6457502B2 JP6457502B2 (ja) | 2019-01-23 |
Family
ID=52779078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016518708A Active JP6457502B2 (ja) | 2013-10-01 | 2014-09-30 | ３−ベンジルスルホニルプロピオニトリルの医薬上の使用 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP3052475B1 (https=) |
| JP (1) | JP6457502B2 (https=) |
| CN (1) | CN105636935B (https=) |
| WO (1) | WO2015050878A1 (https=) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3437685A (en) * | 1964-07-14 | 1969-04-08 | Dow Chemical Co | Dihalosulfones |
| DE3041155A1 (de) * | 1980-10-31 | 1982-06-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2,3-dichlor-sulfonyl-acrylnitrilen |
| JPS58501722A (ja) * | 1981-10-16 | 1983-10-13 | アボツト ラボラトリ−ズ | 〔１↓−（２↓−ベンゾオキサゾリル）ヒドラジノ〕アルキルニトリル誘導体 |
| EP0905126B1 (en) * | 1994-01-22 | 2002-12-04 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
| US5902817A (en) * | 1997-04-09 | 1999-05-11 | Guilford Pharmaceuticals Inc. | Certain sulfoxide and sulfone derivatives |
| US20030212138A1 (en) * | 2002-01-14 | 2003-11-13 | Pharmacia Corporation | Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor |
| US7423064B2 (en) * | 2004-09-24 | 2008-09-09 | Olatec Industries, Llc | Composition for treating bacterial, viral, fungal diseases, inflammation and pain |
| US20100221337A1 (en) * | 2007-02-14 | 2010-09-02 | Logical Therapeutics, Inc. | Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and an h2 receptor antagonist |
| EP2651407B1 (en) * | 2010-12-15 | 2016-12-21 | Olatec Industries LLC | 3-methanesulfonylpropionitrile for treating inflammation and pain |
-
2014
- 2014-09-30 EP EP14851100.9A patent/EP3052475B1/en active Active
- 2014-09-30 CN CN201480054016.9A patent/CN105636935B/zh active Active
- 2014-09-30 WO PCT/US2014/058347 patent/WO2015050878A1/en not_active Ceased
- 2014-09-30 JP JP2016518708A patent/JP6457502B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014503533A5 (https=) | ||
| PH12017501029A1 (en) | Biaryl derivative as gpr120 agonist | |
| EA201800064A1 (ru) | 1,1,1-трифтор-3-гидроксипропан-2-ил карбаматные производные и 1,1,1-трифтор-4-гидроксибутан-2-ил карбаматные производные в качестве ингибиторов magl | |
| EA201270824A1 (ru) | Соединения для уменьшения продукции бета-амилоида | |
| CY1124710T1 (el) | Κετυλιωμενα λιπαρα οξεα, συστημα για την παρασκευη αυτων και χρηση αυτων | |
| JP2014218522A5 (https=) | ||
| MX378007B (es) | Derivados de biarilo como agonistas de gpr120. | |
| JP2016511753A5 (https=) | ||
| JP2017222722A5 (https=) | ||
| BR112013018298A2 (pt) | compostos para a redução da produção de beta-amiloides | |
| JP2017505809A5 (https=) | ||
| JP2013523623A5 (https=) | ||
| RU2016112257A (ru) | Композиция для лечения гипертензии и/или фиброза | |
| JP2016533331A5 (https=) | ||
| JP2016531878A5 (https=) | ||
| JP2016539179A5 (https=) | ||
| CY1117056T1 (el) | Ιβουπροφαινη για ενδοφλεβια εγχυση | |
| BR112014017544A2 (pt) | fitocomposição para o tratamento de dores relacionadas com doenças das articulações | |
| MX2014014817A (es) | Compuestos para el tratamiento de inflamacion y dolor. | |
| EA201491238A1 (ru) | Новая фармацевтическая композиция флурбипрофена и глюкозамина | |
| CA2798420A1 (en) | Combination of an nsaid and an amino acid | |
| MX2015010765A (es) | Metodos y composiciones para tratar y prevenir una lesion intestinal y enfermedades relacionadas a la disfuncion de las uniones estrechas. | |
| Mshvildadze et al. | Corrigendum to “Probiotics and prevention of necrotizing enterocolitis”[Early Human Development, 85 (2009) S71–S74] | |
| EA201592261A1 (ru) | Фармацевтические композиции, включающие агомелатин в форме сокристаллов агомелатина с органической кислотой | |
| PH12015502560A1 (en) | Use of a thiazolo pyrimidinone for the treatment of inflammatory bowel disease |