JP2014503533A5 - - Google Patents
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- Publication number
- JP2014503533A5 JP2014503533A5 JP2013544685A JP2013544685A JP2014503533A5 JP 2014503533 A5 JP2014503533 A5 JP 2014503533A5 JP 2013544685 A JP2013544685 A JP 2013544685A JP 2013544685 A JP2013544685 A JP 2013544685A JP 2014503533 A5 JP2014503533 A5 JP 2014503533A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- inflammation
- compound
- dermatitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 206010061218 Inflammation Diseases 0.000 claims 5
- 208000002193 Pain Diseases 0.000 claims 5
- 230000004054 inflammatory process Effects 0.000 claims 5
- 201000004624 Dermatitis Diseases 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 238000011200 topical administration Methods 0.000 claims 4
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- LQFRYKBDZNPJSW-UHFFFAOYSA-N 3-methylsulfonylpropanenitrile Chemical compound CS(=O)(=O)CCC#N LQFRYKBDZNPJSW-UHFFFAOYSA-N 0.000 claims 1
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 1
- 206010006811 Bursitis Diseases 0.000 claims 1
- 206010008685 Chondritis Diseases 0.000 claims 1
- 208000034656 Contusions Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010012442 Dermatitis contact Diseases 0.000 claims 1
- 208000001640 Fibromyalgia Diseases 0.000 claims 1
- 201000005569 Gout Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 208000029578 Muscle disease Diseases 0.000 claims 1
- 208000021642 Muscular disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010037779 Radiculopathy Diseases 0.000 claims 1
- 208000010040 Sprains and Strains Diseases 0.000 claims 1
- 206010042674 Swelling Diseases 0.000 claims 1
- 208000000491 Tendinopathy Diseases 0.000 claims 1
- 208000023835 Tendon disease Diseases 0.000 claims 1
- 206010043255 Tendonitis Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 208000010247 contact dermatitis Diseases 0.000 claims 1
- 230000009519 contusion Effects 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- XXJWXESWEXIICW-UHFFFAOYSA-N diethylene glycol monoethyl ether Chemical compound CCOCCOCCO XXJWXESWEXIICW-UHFFFAOYSA-N 0.000 claims 1
- 229940075557 diethylene glycol monoethyl ether Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 210000003195 fascia Anatomy 0.000 claims 1
- 239000004503 fine granule Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 229940102223 injectable solution Drugs 0.000 claims 1
- 210000001503 joint Anatomy 0.000 claims 1
- 210000003041 ligament Anatomy 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 238000007910 systemic administration Methods 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 201000004415 tendinitis Diseases 0.000 claims 1
- 210000002435 tendon Anatomy 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42348510P | 2010-12-15 | 2010-12-15 | |
| US61/423,485 | 2010-12-15 | ||
| PCT/US2011/064590 WO2012082718A2 (en) | 2010-12-15 | 2011-12-13 | 3-methanesulfonylpropionitrile for treating inflammation and pain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014503533A JP2014503533A (ja) | 2014-02-13 |
| JP2014503533A5 true JP2014503533A5 (https=) | 2015-01-08 |
| JP5932830B2 JP5932830B2 (ja) | 2016-06-08 |
Family
ID=46235178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013544685A Active JP5932830B2 (ja) | 2010-12-15 | 2011-12-13 | 炎症及び疼痛を処置するための３‐メタンスルホニルプロピオニトリル |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US8476316B2 (https=) |
| EP (1) | EP2651407B1 (https=) |
| JP (1) | JP5932830B2 (https=) |
| KR (1) | KR101849813B1 (https=) |
| CN (1) | CN103260613B (https=) |
| AU (1) | AU2011344030B2 (https=) |
| BR (1) | BR112013014583A2 (https=) |
| CA (1) | CA2820625C (https=) |
| MX (1) | MX2013006708A (https=) |
| TW (1) | TWI522338B (https=) |
| WO (1) | WO2012082718A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6151723B2 (ja) | 2012-02-27 | 2017-06-21 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | ３−メチルスルホニルプロピオニトリルを調製するプロセス |
| CA2875052C (en) * | 2012-06-05 | 2020-07-14 | Olatec Industries Llc | Method for treating skin inflammatory diseases |
| JP6208751B2 (ja) * | 2012-06-05 | 2017-10-04 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | 炎症及び疼痛を治療するための医薬組成物 |
| US9481644B2 (en) | 2012-06-05 | 2016-11-01 | Olatec Therapeutics Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
| WO2013184703A1 (en) * | 2012-06-05 | 2013-12-12 | Olatec Industries Llc | Pharmaceutical composition for treating inflammation and pain |
| JP6228193B2 (ja) | 2012-06-11 | 2017-11-08 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | 炎症及び疼痛を治療するための化合物 |
| US9114122B2 (en) | 2012-06-14 | 2015-08-25 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| WO2013188314A1 (en) * | 2012-06-14 | 2013-12-19 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| PL3369435T3 (pl) | 2013-07-18 | 2020-04-30 | Xalud Therapeutics, Inc. | Kompozycja do leczenia choroby zapalnej stawów |
| JP6461961B2 (ja) | 2013-08-20 | 2019-01-30 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | ジエチル（２−シアノエチル）ホスホネートの医薬組成物および使用 |
| WO2015048328A1 (en) * | 2013-09-26 | 2015-04-02 | Olatec Industries Llc | 3, 4-bis-benzylsulfonylbutanenitrile and its pharmaceutical use |
| US9440916B2 (en) | 2013-09-26 | 2016-09-13 | Olatec Therapeutics Llc | 3, 4-bis-benzylsulfonylbutyronitrile and its pharmaceutical use |
| US9999610B2 (en) | 2013-10-01 | 2018-06-19 | Olatec Therapeutics Llc | Pharmaceutical use of 3-benzylsulfonylpropionitrile |
| EP3052475B1 (en) * | 2013-10-01 | 2018-08-08 | Olatec Therapeutics LLC | Pharmaceutical use of 3-benzylsulfonylpropionitrile |
| US9522878B2 (en) | 2013-10-07 | 2016-12-20 | Olatec Therapeutics Llc | 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use |
| EP3055286A4 (en) * | 2013-10-07 | 2017-05-24 | Olatec Therapeutics LLC | 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use |
| WO2015081188A1 (en) * | 2013-11-27 | 2015-06-04 | Olatec Industries Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
| EP3468530A4 (en) | 2016-06-10 | 2020-03-11 | Clarity Cosmetics Inc. | NON-COMEDOGEN FORMULA FOR HAIR AND SCALP CARE AND METHOD FOR USE |
| ES2970485T3 (es) | 2017-01-06 | 2024-05-29 | Olatec Therapeutics Llc | Composición farmacéutica para su uso en el tratamiento de enfermedades cardiovasculares |
| US10273203B2 (en) | 2017-04-11 | 2019-04-30 | Olatec Therapeutics Llc | Deuterated 3-methanesulfonylpropionitrile |
| WO2019032672A1 (en) * | 2017-08-11 | 2019-02-14 | Olatec Therapeutics Llc | METHOD OF TREATING SCHNITZLER SYNDROME |
| CA3087865A1 (en) | 2018-01-31 | 2019-08-08 | Olatec Therapeutics Llc | Method for preventing or treating alzheimer's disease |
| JP7229565B2 (ja) * | 2018-03-21 | 2023-02-28 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | メラノーマを治療するための方法 |
| WO2020241809A1 (ja) * | 2019-05-31 | 2020-12-03 | 日本たばこ産業株式会社 | 幸福感の評価方法及び幸福感を評価するためのデータ取得方法 |
| AU2020296829B2 (en) * | 2019-06-17 | 2026-01-15 | Olatec Therapeutics Llc | Method for treating asthma |
| EP4045009A4 (en) | 2019-10-14 | 2023-11-01 | Olatec Therapeutics LLC | METHOD FOR TREATING BREAST CANCER |
| WO2022226495A1 (en) * | 2021-04-22 | 2022-10-27 | Olatec Therapeutics Llc | Method for treating spinal cord injury |
| CN118436631B (zh) * | 2024-05-08 | 2025-07-01 | 中国人民解放军军事科学院军事医学研究院 | 达泮舒腈在预防和/或治疗急性放射性肺损伤中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3041155A1 (de) * | 1980-10-31 | 1982-06-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2,3-dichlor-sulfonyl-acrylnitrilen |
| JPS58501722A (ja) * | 1981-10-16 | 1983-10-13 | アボツト ラボラトリ−ズ | 〔１↓−（２↓−ベンゾオキサゾリル）ヒドラジノ〕アルキルニトリル誘導体 |
| US5175192A (en) * | 1984-03-19 | 1992-12-29 | The Rockefeller University | Inhibitors of the advanced glycosylation of proteins and methods of use therefor |
| EP0355049A3 (en) | 1988-08-18 | 1990-06-13 | Zeneca Limited | Heterocyclic compounds |
| US5348838A (en) | 1991-07-31 | 1994-09-20 | Kabushiki Kaisha Toshiba | Photosensitive composition comprising alkali soluble binder and photoacid generator having sulfonyl group |
| KR100294084B1 (ko) * | 1998-06-02 | 2001-09-22 | 성재갑 | 비-스테로이드성소염진통제의경피흡수투여용조성물및이를포함하는경피흡수투여용제형 |
| WO1999039713A1 (en) | 1998-02-09 | 1999-08-12 | Chong Kun Dang Pharmaceutical Corp. | Piroxicam-containing hydroalcoholic gel composition |
| US6551615B1 (en) * | 2001-10-18 | 2003-04-22 | M/S. Strides Arcolab Limited | Dexibuprofen-containing soft gelatin capsules and process for preparing the same |
| CN1528284A (zh) * | 2003-10-06 | 2004-09-15 | 南昌弘益科技有限公司 | 蔊菜素滴丸及其制备方法 |
| US7423064B2 (en) | 2004-09-24 | 2008-09-09 | Olatec Industries, Llc | Composition for treating bacterial, viral, fungal diseases, inflammation and pain |
| PT1988779E (pt) * | 2006-02-16 | 2015-09-04 | Anacor Pharmaceuticals Inc | Moléculas pequenas contendo boro como agentes antiinflamatórios |
| BRPI0621416A2 (pt) * | 2006-03-20 | 2011-12-06 | Olatec Ind Llc | composição para o tratamento de doenças bacterianas, virais, fúngicas, inflamação e dor |
| US20100221337A1 (en) * | 2007-02-14 | 2010-09-02 | Logical Therapeutics, Inc. | Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and an h2 receptor antagonist |
| KR20150065941A (ko) * | 2008-03-06 | 2015-06-15 | 아나코르 파마슈티칼스 인코포레이티드 | 소염제로써 붕소가 함유된 소분자 |
| WO2010018814A1 (ja) | 2008-08-12 | 2010-02-18 | 宇部興産株式会社 | 非水電解液及びそれを用いたリチウム電池 |
| AU2010226794A1 (en) * | 2009-03-18 | 2011-10-27 | Olatec Industries Llc | Compounds for treating inflammation and pain |
-
2011
- 2011-12-13 EP EP11849401.2A patent/EP2651407B1/en active Active
- 2011-12-13 BR BR112013014583A patent/BR112013014583A2/pt not_active Application Discontinuation
- 2011-12-13 MX MX2013006708A patent/MX2013006708A/es active IP Right Grant
- 2011-12-13 AU AU2011344030A patent/AU2011344030B2/en active Active
- 2011-12-13 JP JP2013544685A patent/JP5932830B2/ja active Active
- 2011-12-13 CA CA2820625A patent/CA2820625C/en active Active
- 2011-12-13 US US13/324,777 patent/US8476316B2/en active Active
- 2011-12-13 KR KR1020137018100A patent/KR101849813B1/ko active Active
- 2011-12-13 CN CN201180060698.0A patent/CN103260613B/zh active Active
- 2011-12-13 WO PCT/US2011/064590 patent/WO2012082718A2/en not_active Ceased
- 2011-12-15 TW TW100146435A patent/TWI522338B/zh active
-
2013
- 2013-02-05 US US13/759,676 patent/US8829046B2/en active Active
-
2014
- 2014-03-17 US US14/216,664 patent/US8975297B2/en active Active
-
2015
- 2015-03-05 US US14/639,781 patent/US9492420B2/en active Active
-
2016
- 2016-11-11 US US15/349,161 patent/US9770428B2/en active Active
-
2017
- 2017-09-22 US US15/712,269 patent/US10080735B2/en active Active
-
2018
- 2018-09-24 US US16/139,351 patent/US10500184B2/en active Active
-
2019
- 2019-12-05 US US16/704,921 patent/US11229620B2/en active Active
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