BR112013014583A2 - composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrila - Google Patents
composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrilaInfo
- Publication number
- BR112013014583A2 BR112013014583A2 BR112013014583A BR112013014583A BR112013014583A2 BR 112013014583 A2 BR112013014583 A2 BR 112013014583A2 BR 112013014583 A BR112013014583 A BR 112013014583A BR 112013014583 A BR112013014583 A BR 112013014583A BR 112013014583 A2 BR112013014583 A2 BR 112013014583A2
- Authority
- BR
- Brazil
- Prior art keywords
- treating
- methanesulfonylpropionitrile
- preparing
- methods
- pharmaceutical composition
- Prior art date
Links
- LQFRYKBDZNPJSW-UHFFFAOYSA-N 3-methylsulfonylpropanenitrile Chemical compound CS(=O)(=O)CCC#N LQFRYKBDZNPJSW-UHFFFAOYSA-N 0.000 title 1
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/02—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C255/03—Mononitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42348510P | 2010-12-15 | 2010-12-15 | |
| PCT/US2011/064590 WO2012082718A2 (en) | 2010-12-15 | 2011-12-13 | 3-methanesulfonylpropionitrile for treating inflammation and pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013014583A2 true BR112013014583A2 (pt) | 2016-09-20 |
Family
ID=46235178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013014583A BR112013014583A2 (pt) | 2010-12-15 | 2011-12-13 | composição farmacêutica, e, métodos para o tratamento de inflamação, para o tratamento da dor, e para preparar 3-metanossulfonilpropionitrila |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US8476316B2 (https=) |
| EP (1) | EP2651407B1 (https=) |
| JP (1) | JP5932830B2 (https=) |
| KR (1) | KR101849813B1 (https=) |
| CN (1) | CN103260613B (https=) |
| AU (1) | AU2011344030B2 (https=) |
| BR (1) | BR112013014583A2 (https=) |
| CA (1) | CA2820625C (https=) |
| MX (1) | MX2013006708A (https=) |
| TW (1) | TWI522338B (https=) |
| WO (1) | WO2012082718A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6151723B2 (ja) | 2012-02-27 | 2017-06-21 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | ３−メチルスルホニルプロピオニトリルを調製するプロセス |
| CA2875052C (en) * | 2012-06-05 | 2020-07-14 | Olatec Industries Llc | Method for treating skin inflammatory diseases |
| JP6208751B2 (ja) * | 2012-06-05 | 2017-10-04 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | 炎症及び疼痛を治療するための医薬組成物 |
| US9481644B2 (en) | 2012-06-05 | 2016-11-01 | Olatec Therapeutics Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
| WO2013184703A1 (en) * | 2012-06-05 | 2013-12-12 | Olatec Industries Llc | Pharmaceutical composition for treating inflammation and pain |
| JP6228193B2 (ja) | 2012-06-11 | 2017-11-08 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | 炎症及び疼痛を治療するための化合物 |
| US9114122B2 (en) | 2012-06-14 | 2015-08-25 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| WO2013188314A1 (en) * | 2012-06-14 | 2013-12-19 | Olatec Industries Llc | Compounds for treating inflammation and pain |
| PL3369435T3 (pl) | 2013-07-18 | 2020-04-30 | Xalud Therapeutics, Inc. | Kompozycja do leczenia choroby zapalnej stawów |
| JP6461961B2 (ja) | 2013-08-20 | 2019-01-30 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | ジエチル（２−シアノエチル）ホスホネートの医薬組成物および使用 |
| WO2015048328A1 (en) * | 2013-09-26 | 2015-04-02 | Olatec Industries Llc | 3, 4-bis-benzylsulfonylbutanenitrile and its pharmaceutical use |
| US9440916B2 (en) | 2013-09-26 | 2016-09-13 | Olatec Therapeutics Llc | 3, 4-bis-benzylsulfonylbutyronitrile and its pharmaceutical use |
| US9999610B2 (en) | 2013-10-01 | 2018-06-19 | Olatec Therapeutics Llc | Pharmaceutical use of 3-benzylsulfonylpropionitrile |
| EP3052475B1 (en) * | 2013-10-01 | 2018-08-08 | Olatec Therapeutics LLC | Pharmaceutical use of 3-benzylsulfonylpropionitrile |
| US9522878B2 (en) | 2013-10-07 | 2016-12-20 | Olatec Therapeutics Llc | 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use |
| EP3055286A4 (en) * | 2013-10-07 | 2017-05-24 | Olatec Therapeutics LLC | 4-methylsulfonyl-2-butenenitrile and its pharmaceutical use |
| WO2015081188A1 (en) * | 2013-11-27 | 2015-06-04 | Olatec Industries Llc | Pharmaceutical composition comprising omega-(arylsulfonyl)alkylnitrile |
| EP3468530A4 (en) | 2016-06-10 | 2020-03-11 | Clarity Cosmetics Inc. | NON-COMEDOGEN FORMULA FOR HAIR AND SCALP CARE AND METHOD FOR USE |
| ES2970485T3 (es) | 2017-01-06 | 2024-05-29 | Olatec Therapeutics Llc | Composición farmacéutica para su uso en el tratamiento de enfermedades cardiovasculares |
| US10273203B2 (en) | 2017-04-11 | 2019-04-30 | Olatec Therapeutics Llc | Deuterated 3-methanesulfonylpropionitrile |
| WO2019032672A1 (en) * | 2017-08-11 | 2019-02-14 | Olatec Therapeutics Llc | METHOD OF TREATING SCHNITZLER SYNDROME |
| CA3087865A1 (en) | 2018-01-31 | 2019-08-08 | Olatec Therapeutics Llc | Method for preventing or treating alzheimer's disease |
| JP7229565B2 (ja) * | 2018-03-21 | 2023-02-28 | オラテック セラピューティクス リミティド ライアビリティ カンパニー | メラノーマを治療するための方法 |
| WO2020241809A1 (ja) * | 2019-05-31 | 2020-12-03 | 日本たばこ産業株式会社 | 幸福感の評価方法及び幸福感を評価するためのデータ取得方法 |
| AU2020296829B2 (en) * | 2019-06-17 | 2026-01-15 | Olatec Therapeutics Llc | Method for treating asthma |
| EP4045009A4 (en) | 2019-10-14 | 2023-11-01 | Olatec Therapeutics LLC | METHOD FOR TREATING BREAST CANCER |
| WO2022226495A1 (en) * | 2021-04-22 | 2022-10-27 | Olatec Therapeutics Llc | Method for treating spinal cord injury |
| CN118436631B (zh) * | 2024-05-08 | 2025-07-01 | 中国人民解放军军事科学院军事医学研究院 | 达泮舒腈在预防和/或治疗急性放射性肺损伤中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3041155A1 (de) * | 1980-10-31 | 1982-06-09 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von 2,3-dichlor-sulfonyl-acrylnitrilen |
| JPS58501722A (ja) * | 1981-10-16 | 1983-10-13 | アボツト ラボラトリ−ズ | 〔１↓−（２↓−ベンゾオキサゾリル）ヒドラジノ〕アルキルニトリル誘導体 |
| US5175192A (en) * | 1984-03-19 | 1992-12-29 | The Rockefeller University | Inhibitors of the advanced glycosylation of proteins and methods of use therefor |
| EP0355049A3 (en) | 1988-08-18 | 1990-06-13 | Zeneca Limited | Heterocyclic compounds |
| US5348838A (en) | 1991-07-31 | 1994-09-20 | Kabushiki Kaisha Toshiba | Photosensitive composition comprising alkali soluble binder and photoacid generator having sulfonyl group |
| KR100294084B1 (ko) * | 1998-06-02 | 2001-09-22 | 성재갑 | 비-스테로이드성소염진통제의경피흡수투여용조성물및이를포함하는경피흡수투여용제형 |
| WO1999039713A1 (en) | 1998-02-09 | 1999-08-12 | Chong Kun Dang Pharmaceutical Corp. | Piroxicam-containing hydroalcoholic gel composition |
| US6551615B1 (en) * | 2001-10-18 | 2003-04-22 | M/S. Strides Arcolab Limited | Dexibuprofen-containing soft gelatin capsules and process for preparing the same |
| CN1528284A (zh) * | 2003-10-06 | 2004-09-15 | 南昌弘益科技有限公司 | 蔊菜素滴丸及其制备方法 |
| US7423064B2 (en) | 2004-09-24 | 2008-09-09 | Olatec Industries, Llc | Composition for treating bacterial, viral, fungal diseases, inflammation and pain |
| PT1988779E (pt) * | 2006-02-16 | 2015-09-04 | Anacor Pharmaceuticals Inc | Moléculas pequenas contendo boro como agentes antiinflamatórios |
| BRPI0621416A2 (pt) * | 2006-03-20 | 2011-12-06 | Olatec Ind Llc | composição para o tratamento de doenças bacterianas, virais, fúngicas, inflamação e dor |
| US20100221337A1 (en) * | 2007-02-14 | 2010-09-02 | Logical Therapeutics, Inc. | Method of treating arthritis, pain or inflammation with naproxen 2(methanesulfonyl)ethyl ester and an h2 receptor antagonist |
| KR20150065941A (ko) * | 2008-03-06 | 2015-06-15 | 아나코르 파마슈티칼스 인코포레이티드 | 소염제로써 붕소가 함유된 소분자 |
| WO2010018814A1 (ja) | 2008-08-12 | 2010-02-18 | 宇部興産株式会社 | 非水電解液及びそれを用いたリチウム電池 |
| AU2010226794A1 (en) * | 2009-03-18 | 2011-10-27 | Olatec Industries Llc | Compounds for treating inflammation and pain |
-
2011
- 2011-12-13 EP EP11849401.2A patent/EP2651407B1/en active Active
- 2011-12-13 BR BR112013014583A patent/BR112013014583A2/pt not_active Application Discontinuation
- 2011-12-13 MX MX2013006708A patent/MX2013006708A/es active IP Right Grant
- 2011-12-13 AU AU2011344030A patent/AU2011344030B2/en active Active
- 2011-12-13 JP JP2013544685A patent/JP5932830B2/ja active Active
- 2011-12-13 CA CA2820625A patent/CA2820625C/en active Active
- 2011-12-13 US US13/324,777 patent/US8476316B2/en active Active
- 2011-12-13 KR KR1020137018100A patent/KR101849813B1/ko active Active
- 2011-12-13 CN CN201180060698.0A patent/CN103260613B/zh active Active
- 2011-12-13 WO PCT/US2011/064590 patent/WO2012082718A2/en not_active Ceased
- 2011-12-15 TW TW100146435A patent/TWI522338B/zh active
-
2013
- 2013-02-05 US US13/759,676 patent/US8829046B2/en active Active
-
2014
- 2014-03-17 US US14/216,664 patent/US8975297B2/en active Active
-
2015
- 2015-03-05 US US14/639,781 patent/US9492420B2/en active Active
-
2016
- 2016-11-11 US US15/349,161 patent/US9770428B2/en active Active
-
2017
- 2017-09-22 US US15/712,269 patent/US10080735B2/en active Active
-
2018
- 2018-09-24 US US16/139,351 patent/US10500184B2/en active Active
-
2019
- 2019-12-05 US US16/704,921 patent/US11229620B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |