JP2016530219A5 - - Google Patents
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- Publication number
- JP2016530219A5 JP2016530219A5 JP2016517990A JP2016517990A JP2016530219A5 JP 2016530219 A5 JP2016530219 A5 JP 2016530219A5 JP 2016517990 A JP2016517990 A JP 2016517990A JP 2016517990 A JP2016517990 A JP 2016517990A JP 2016530219 A5 JP2016530219 A5 JP 2016530219A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- gemcitabine
- vitamin
- agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361831515P | 2013-06-05 | 2013-06-05 | |
| US61/831,515 | 2013-06-05 | ||
| PCT/US2014/041063 WO2014197680A1 (en) | 2013-06-05 | 2014-06-05 | Vitamin d receptor agonists to treat diseases involving cxcl12 activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016530219A JP2016530219A (ja) | 2016-09-29 |
| JP2016530219A5 true JP2016530219A5 (https=) | 2017-07-13 |
Family
ID=52008582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016517990A Pending JP2016530219A (ja) | 2013-06-05 | 2014-06-05 | Ｃｘｃｌ１２活性に関与する疾患を処置するためのビタミンｄ受容体アゴニスト |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9895381B2 (https=) |
| EP (2) | EP3473299A1 (https=) |
| JP (1) | JP2016530219A (https=) |
| CN (1) | CN105451818A (https=) |
| AU (1) | AU2014274864B2 (https=) |
| BR (1) | BR112015030518A2 (https=) |
| CA (1) | CA2914487A1 (https=) |
| MX (1) | MX2015016715A (https=) |
| WO (1) | WO2014197680A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105473147A (zh) | 2013-04-24 | 2016-04-06 | 萨克生物研究学院 | 维生素d受体/smad基因组回路门纤维化反应 |
| CN109069426B (zh) | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| PL3393468T3 (pl) | 2015-12-22 | 2023-01-23 | X4 Pharmaceuticals, Inc. | Metody leczenia niedoboru odporności |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN106109476A (zh) * | 2016-06-13 | 2016-11-16 | 中山大学 | 骨化二醇作为吲哚胺2,3‑双加氧酶‑1抑制剂的用途 |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
| WO2017223243A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| WO2019023149A1 (en) | 2017-07-24 | 2019-01-31 | Salk Institute For Biological Studies | USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| JP7377486B2 (ja) * | 2018-09-10 | 2023-11-10 | 国立大学法人東京工業大学 | 多能性幹細胞から腸細胞の作製方法 |
| WO2020054659A1 (ja) * | 2018-09-10 | 2020-03-19 | 国立大学法人東京工業大学 | 多能性幹細胞から腸細胞の作製方法 |
| CN115515589A (zh) * | 2020-02-14 | 2022-12-23 | 萨克生物研究学院 | Ulk1/2抑制剂及其使用方法 |
| KR20220153582A (ko) | 2020-02-14 | 2022-11-18 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 마크로시클릭 ulk1/2 억제제 |
| CA3171250A1 (en) | 2020-03-10 | 2021-09-16 | E. Lynne KELLEY | Methods for treating neutropenia |
| CN113350362A (zh) * | 2021-06-11 | 2021-09-07 | 扬州大学附属医院 | 维生素d受体激动剂在制备预防和/或治疗急性胰腺炎的药物中的应用 |
| IL321943A (en) * | 2023-01-06 | 2025-09-01 | Adge Pharmaceuticals Inc | Method for treating metabolic syndrome |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| AUPO727097A0 (en) * | 1997-06-10 | 1997-07-03 | Unisearch Limited | Method of treatment of hepatoma and pharmaceutical compositions for use therein |
| US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
| US20030228689A1 (en) | 2002-05-31 | 2003-12-11 | Isis Pharmaceuticals Inc. | Antisense modulation of G protein-coupled receptor kinase 6 expression |
| CA2495962A1 (en) | 2002-08-19 | 2004-03-04 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
| WO2004047673A2 (en) | 2002-11-21 | 2004-06-10 | Novacea, Inc. | Treatment of liver disease with active vitamin d compounds |
| WO2004110380A2 (en) | 2003-06-11 | 2004-12-23 | Novacea, Inc. | Treatment of immune-mediated disorders with active vitamin d compounds alone or in combination with other therapeutic agents |
| US20050124591A1 (en) | 2003-07-29 | 2005-06-09 | Jin Tian | Use of vitamin Ds to treat kidney disease |
| US20050148557A1 (en) | 2003-07-29 | 2005-07-07 | Jin Tian | Use of Vitamin Ds to treat kidney disease |
| WO2005117542A2 (en) * | 2004-05-10 | 2005-12-15 | Novacea, Inc. | Treatment of pancreatic cancer with active vitamin d compounds in combination with other treatments |
| WO2006032299A1 (en) | 2004-09-24 | 2006-03-30 | Susanna Miettinen | Use of inhibitors of 24-hydroxylase in the treatment of cancer |
| US20060135610A1 (en) | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Cardiovascular compositions |
| US8968806B2 (en) | 2005-04-26 | 2015-03-03 | Sean Joseph Delaney | Method and system for creating and using a supplement to balance animal diets |
| CN101528309A (zh) | 2006-08-25 | 2009-09-09 | 库伽尔生物科技公司 | 包括给予维生素d化合物和另外的治疗剂的治疗癌症的方法 |
| TW200833345A (en) | 2006-11-01 | 2008-08-16 | Novacea Inc | Use of vitamin D compounds and mimics thereof to enhance delivery of therapeutics and oxygen to tumors and other tissues |
| EP2155769B1 (en) | 2007-05-04 | 2012-06-27 | Katholieke Universiteit Leuven KU Leuven Research & Development | Tissue degeneration protection |
| US8318708B2 (en) * | 2007-11-06 | 2012-11-27 | Salk Institute For Biological Studies | Use of vitamin D receptor agonists, ligands, and precursors to treat pancreatic fibrosis |
| CA2963341A1 (en) | 2007-11-06 | 2009-05-14 | University Of Sydney | Use of vitamin d receptor agonists and precursors to treat fibrosis |
| RU2537181C2 (ru) * | 2009-03-12 | 2014-12-27 | Нордик Байосайенс А/С | Лечение диабета и метаболического синдрома |
| PL388252A1 (pl) * | 2009-06-10 | 2010-12-20 | Instytut Farmaceutyczny | Terapia skojarzona raka jelita grubego |
| IT1397901B1 (it) * | 2010-01-26 | 2013-02-04 | Consiglio Nazionale Ricerche | Peptidi ciclici che legano il recettore cxcr4 e relativi usi in campo medico e diagnostico. |
| CA2797095A1 (en) * | 2010-05-13 | 2011-11-17 | Indiana University Research And Technology Corporation | Glucagon superfamily peptides exhibiting nuclear hormone receptor activity |
| WO2012127037A2 (en) | 2011-03-24 | 2012-09-27 | Leo Pharma A/S | A composition comprising lipid nanoparticles and a corticosteroid or vitamin d derivative |
| JP2013056834A (ja) | 2011-09-07 | 2013-03-28 | Okayama Univ | 線維化疾患治療剤 |
| CN102342914A (zh) | 2011-10-07 | 2012-02-08 | 南昌大学 | 卡泊三醇固体脂质纳米粒及其制备方法 |
-
2014
- 2014-06-05 WO PCT/US2014/041063 patent/WO2014197680A1/en not_active Ceased
- 2014-06-05 EP EP18206167.1A patent/EP3473299A1/en not_active Withdrawn
- 2014-06-05 MX MX2015016715A patent/MX2015016715A/es unknown
- 2014-06-05 JP JP2016517990A patent/JP2016530219A/ja active Pending
- 2014-06-05 BR BR112015030518A patent/BR112015030518A2/pt not_active IP Right Cessation
- 2014-06-05 AU AU2014274864A patent/AU2014274864B2/en not_active Ceased
- 2014-06-05 CN CN201480043580.0A patent/CN105451818A/zh active Pending
- 2014-06-05 CA CA2914487A patent/CA2914487A1/en not_active Abandoned
- 2014-06-05 EP EP14806812.5A patent/EP3003486A4/en not_active Withdrawn
-
2015
- 2015-12-04 US US14/959,105 patent/US9895381B2/en active Active
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