JP2016528027A5 - - Google Patents

Download PDF

Info

Publication number
JP2016528027A5
JP2016528027A5 JP2016521890A JP2016521890A JP2016528027A5 JP 2016528027 A5 JP2016528027 A5 JP 2016528027A5 JP 2016521890 A JP2016521890 A JP 2016521890A JP 2016521890 A JP2016521890 A JP 2016521890A JP 2016528027 A5 JP2016528027 A5 JP 2016528027A5
Authority
JP
Japan
Prior art keywords
well
sample
containing fluid
fluid
passage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016521890A
Other languages
English (en)
Japanese (ja)
Other versions
JP6449266B2 (ja
JP2016528027A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/043715 external-priority patent/WO2014205447A2/en
Publication of JP2016528027A publication Critical patent/JP2016528027A/ja
Publication of JP2016528027A5 publication Critical patent/JP2016528027A5/ja
Application granted granted Critical
Publication of JP6449266B2 publication Critical patent/JP6449266B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016521890A 2013-06-21 2014-06-23 流体ピックアップを備えるマイクロ流体システム Active JP6449266B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361838063P 2013-06-21 2013-06-21
US61/838,063 2013-06-21
PCT/US2014/043715 WO2014205447A2 (en) 2013-06-21 2014-06-23 Microfluidic system with fluid pickups

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018228253A Division JP6790044B2 (ja) 2013-06-21 2018-12-05 流体ピックアップを備えるマイクロ流体システム

Publications (3)

Publication Number Publication Date
JP2016528027A JP2016528027A (ja) 2016-09-15
JP2016528027A5 true JP2016528027A5 (https=) 2017-07-27
JP6449266B2 JP6449266B2 (ja) 2019-01-09

Family

ID=52105551

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016521890A Active JP6449266B2 (ja) 2013-06-21 2014-06-23 流体ピックアップを備えるマイクロ流体システム
JP2018228253A Active JP6790044B2 (ja) 2013-06-21 2018-12-05 流体ピックアップを備えるマイクロ流体システム
JP2020184645A Active JP7110300B2 (ja) 2013-06-21 2020-11-04 流体ピックアップを備えるマイクロ流体システム

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018228253A Active JP6790044B2 (ja) 2013-06-21 2018-12-05 流体ピックアップを備えるマイクロ流体システム
JP2020184645A Active JP7110300B2 (ja) 2013-06-21 2020-11-04 流体ピックアップを備えるマイクロ流体システム

Country Status (7)

Country Link
US (3) US9409174B2 (https=)
EP (1) EP3011302B1 (https=)
JP (3) JP6449266B2 (https=)
CN (2) CN109738224B (https=)
AU (1) AU2014284148B2 (https=)
SG (1) SG11201510439PA (https=)
WO (1) WO2014205447A2 (https=)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040002147A1 (en) 1999-12-29 2004-01-01 Desantis Grace Nitrilases
EP2292784A3 (en) 2001-02-21 2011-06-22 Verenium Corporation Enzymes having alpha amylase activity and methods of use thereof
DK2327765T3 (en) 2001-06-21 2015-07-13 Basf Enzymes Llc nitrilases
US7226771B2 (en) 2002-04-19 2007-06-05 Diversa Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
PT1497418E (pt) 2002-04-19 2013-01-25 Dsm Ip Assets Bv Fosfolípases, ácidos nucleicos que as codificam e métodos para as preparar e utilizar
KR20080045764A (ko) 2002-06-14 2008-05-23 신젠타 파티서페이션즈 아게 자일라나제, 이를 암호화하는 핵산, 및 이의 제조 및 사용방법
CN102618564B (zh) 2003-03-06 2014-10-29 维莱尼姆公司 淀粉酶、编码它们的核酸及其制备和应用方法
HUE030493T2 (en) 2003-04-04 2017-05-29 Basf Enzymes Llc Pectate lyases, nucleic acids and processes encoding them for their production and use
US7960148B2 (en) 2003-07-02 2011-06-14 Verenium Corporation Glucanases, nucleic acids encoding them and methods for making and using them
CA2535526C (en) 2003-08-11 2015-09-29 Diversa Corporation Laccases, nucleic acids encoding them and methods for making and using them
AU2005264938B2 (en) 2004-06-16 2011-11-24 Verenium Corporation Compositions and methods for enzymatic decolorization of chlorophyll
EP2886658A1 (en) 2005-03-10 2015-06-24 BASF Enzymes LLC Lyase enzymes, nucleic acids encoding them and methods for making and using them
CA2611859C (en) 2005-03-15 2015-03-31 Verenium Corporation Cellulases, nucleic acids encoding them and methods for making and using them
NZ595497A (en) 2006-02-10 2013-09-27 Verenium Corp Cellulolytic enzymes, nucleic acids encoding them and methods for making and using them
TR201809912T4 (tr) 2006-02-14 2018-07-23 Bp Corp North America Inc Ksilanazlar, bunları kodlayan nükleik asitler ve bunları yapmak ve kullanmak için yöntemler.
AU2007223086B2 (en) 2006-03-07 2013-09-26 Basf Enzymes Llc Aldolases, nucleic acids encoding them and methods for making and using them
MX2008011477A (es) 2006-03-07 2008-09-23 Cargill Inc Aldolasas, acidos nucleicos que las codifican y metodos para hacerlas y usarlas.
DK2069389T3 (en) 2006-08-04 2015-01-12 Bp Corp North America Inc Glucanases, nucleic acids encoding them, and processes for their preparation and use
EP2057274B1 (en) 2006-09-21 2013-12-11 DSM IP Assets B.V. Phospholipases, nucleic acids encoding them and methods for making and using them
PL2479267T3 (pl) 2006-12-21 2017-06-30 Basf Enzymes Llc Amylazy i glukoamylazy, kwasy nukleinowe kodujące te związki oraz sposoby wytwarzania tych związków oraz stosowania ich
NZ598285A (en) 2007-01-30 2013-10-25 Syngenta Participations Ag Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them
DK2115153T3 (da) 2007-03-01 2013-09-08 Bp Corp North America Inc Nitrilaser, nucleinsyrer som koder for dem og fremgangsmåder til at fremstille og anvende disse
BRPI0817811A2 (pt) 2007-10-03 2014-10-14 Verenium Corp Xilanases, ácidos nucleicos que codificam as mesmas e métodos para fabricação e uso das mesmas.
CN104651381A (zh) 2008-01-03 2015-05-27 巴斯夫酶有限责任公司 转移酶和氧化还原酶、编码它们的核酸以及其制备和应用方法
UA109884C2 (uk) 2009-10-16 2015-10-26 Поліпептид, що має активність ферменту фосфатидилінозитол-специфічної фосфоліпази с, нуклеїнова кислота, що його кодує, та спосіб його виробництва і застосування
UA111708C2 (uk) 2009-10-16 2016-06-10 Бандж Ойлз, Інк. Спосіб рафінування олії
JP6449266B2 (ja) 2013-06-21 2019-01-09 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド 流体ピックアップを備えるマイクロ流体システム
EP3285928B1 (en) * 2015-04-22 2020-04-08 Stilla Technologies Contact-less priming method for loading a solution in a microfluidic device and associated system
KR102134953B1 (ko) 2015-05-29 2020-07-16 일루미나, 인코포레이티드 지정된 반응을 수행하기 위한 샘플 캐리어 및 검정 시스템
BR112018008629B1 (pt) * 2015-11-04 2020-11-17 Nitto Denko Corporation aparelho para ensaio de um biofluido, aparelho para contenção e dispensa de amostras de biofluido e sistema para dispensa e ensaio de biofluido
CN108700609A (zh) * 2015-12-30 2018-10-23 生物辐射实验室股份有限公司 具有自动校准的液滴测定系统
EP3420107A4 (en) 2016-02-22 2019-07-31 BioFire Defense, LLC RAPID PCR DEVICES AND METHODS
JP6622147B2 (ja) * 2016-06-16 2019-12-18 株式会社エンプラス エマルション生成部材、およびこれを用いたサンプル採取管、ならびに採血管
JP7010926B2 (ja) * 2016-07-28 2022-01-26 バイオファイア・ダイアグノスティクス,リミテッド・ライアビリティ・カンパニー 自己完結型の核酸処理
USD803173S1 (en) * 2016-09-07 2017-11-21 EMULATE, Inc. Perfusion module lid without pressure features
GB201617869D0 (en) * 2016-10-21 2016-12-07 Blacktrace Holdings Limited A microfluidic device
CN108148744A (zh) * 2016-12-06 2018-06-12 中山百慧生物科技有限公司 一种液滴数字pcr芯片及相应检测方法和检测系统
CN108148743A (zh) * 2016-12-06 2018-06-12 中山百慧生物科技有限公司 一种液滴数字pcr芯片及相应检测方法和检测系统
WO2018148693A1 (en) 2017-02-13 2018-08-16 Bio-Rad Laboratories, Inc. System, method, and device for forming an array of emulsions
CN106984370B (zh) * 2017-05-08 2019-09-20 北京旌准医疗科技有限公司 一种基于微流控芯片的自动进样系统
EP4435113B1 (en) 2017-05-18 2025-12-10 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10544413B2 (en) 2017-05-18 2020-01-28 10X Genomics, Inc. Methods and systems for sorting droplets and beads
GB2562762B (en) * 2017-05-24 2022-07-13 Univ Heriot Watt Microfluidic mixing
KR101951405B1 (ko) * 2017-06-28 2019-05-08 주식회사 파나진 시료 시약 반응 분석용 키트, 이를 이용한 표적 핵산 검출 장치 및 방법
US11499183B2 (en) * 2017-06-28 2022-11-15 Bio-Rad Laboratories, Inc. System and method for droplet detection
US10610865B2 (en) 2017-08-22 2020-04-07 10X Genomics, Inc. Droplet forming devices and system with differential surface properties
WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
US11045805B2 (en) 2017-11-01 2021-06-29 Bio-Rad Laboratories, Inc. Microfluidic system and method for arranging objects
CN111432726A (zh) 2017-11-02 2020-07-17 米密德诊断学有限公司 用于分析体液的卡盒及系统
JP6967427B2 (ja) * 2017-11-06 2021-11-17 Nok株式会社 ガスケットおよび密封構造
WO2019110591A1 (en) * 2017-12-06 2019-06-13 Samplix Aps A microfluidic device and a method for provision of emulsion droplets
KR101951670B1 (ko) 2017-12-13 2019-02-25 한국과학기술원 미세액적 내 유전자 검출을 위한 광학장치
EP3501651B1 (en) * 2017-12-22 2024-03-06 IMEC vzw Microfluidic routing
GB2572408B8 (en) * 2018-03-29 2022-06-22 Univ Heriot Watt Fluidic device
US20210031201A1 (en) * 2018-04-15 2021-02-04 Optofluidic Bioassay, Llc Differential pressure assisted drainage system
KR101891968B1 (ko) * 2018-05-30 2018-08-27 티엔에스(주) 하이브리드 유전자칩
KR101891558B1 (ko) * 2018-06-15 2018-08-27 티엔에스(주) 하이브리드 유전자칩용 유전자 분석 장치
WO2020030090A1 (en) * 2018-08-09 2020-02-13 Versitech Limited Systems for automated handling of fluid samples into microfluidic droplets for in vitro diagnostic
CN108728347A (zh) * 2018-08-27 2018-11-02 中国农业科学院农业质量标准与检测技术研究所 一种基因检测装置
CN109351369B (zh) * 2018-10-23 2021-01-26 深圳市博瑞生物科技有限公司 微流控液滴生成芯片
CN109351368B (zh) * 2018-10-23 2021-04-30 深圳市博瑞生物科技有限公司 微流控芯片
SG11202012943UA (en) * 2019-01-31 2021-01-28 Illumina Inc Thermoformed, injection molded, and/or overmolded microfluidic structures and techniques for making the same
US20220193678A1 (en) * 2019-04-08 2022-06-23 Technion Research And Development Foundation, Ltd. Multiplexed array of nanoliter droplet array device
EP4009055A4 (en) * 2019-08-01 2023-06-07 Nippon Chemiphar Co., Ltd. REAGENT CARTRIDGE
WO2021077087A1 (en) * 2019-10-18 2021-04-22 Morningbird Media Corporation Three-dimensional printer with multihead extruder and compositions for use therein
CN111304060A (zh) * 2020-03-30 2020-06-19 西安天隆科技有限公司 一种微液滴生成芯片
US20230122421A1 (en) * 2020-04-01 2023-04-20 Merck Patent Gmbh Emulsification device
CN111826273B (zh) * 2020-07-22 2023-03-21 上海逢伙泰企业管理有限公司 一种用于核酸检测的自动化全封闭微流控芯片
DE102020211697A1 (de) * 2020-09-18 2022-03-24 Robert Bosch Gesellschaft mit beschränkter Haftung Mikrofluidische Vorrichtung
WO2022060548A1 (en) * 2020-09-18 2022-03-24 Microgem International Plc Method and system for sample collection, storage, preparation and detection
US20250177973A1 (en) * 2022-02-25 2025-06-05 Redbud Labs, Inc. Sample tube connectors and methods for attaching a microfluidics device to a sample tube
CN114672412A (zh) * 2022-05-30 2022-06-28 季华实验室 一种微滴式数字聚合酶链反应芯片
EP4431185A1 (en) * 2023-03-17 2024-09-18 CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Développement Liquid handling cover for a microfluidic device

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US20020092767A1 (en) * 1997-09-19 2002-07-18 Aclara Biosciences, Inc. Multiple array microfluidic device units
US6902703B2 (en) * 1999-05-03 2005-06-07 Ljl Biosystems, Inc. Integrated sample-processing system
US20030215957A1 (en) 1998-02-20 2003-11-20 Tony Lemmo Multi-channel dispensing system
WO2000049382A2 (en) * 1999-02-16 2000-08-24 The Perkin-Elmer Corporation Bead dispensing system
US8709153B2 (en) 1999-06-28 2014-04-29 California Institute Of Technology Microfludic protein crystallography techniques
JP4119649B2 (ja) 1999-08-25 2008-07-16 カリパー・ライフ・サイエンシズ・インコーポレーテッド 単一真空源を有する高スループットシステムにおける稀釈
NL1017374C2 (nl) * 2001-02-15 2002-08-16 Univ Delft Tech Inrichting voor het uitvoeren van een reactie, alsmede een werkwijze voor het uitvoeren van een reactie in de inrichting.
WO2002072423A1 (en) * 2001-03-09 2002-09-19 Biomicro Systems, Inc. Microplate lid
US20020187557A1 (en) * 2001-06-07 2002-12-12 Hobbs Steven E. Systems and methods for introducing samples into microfluidic devices
US6877528B2 (en) * 2002-04-17 2005-04-12 Cytonome, Inc. Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US7445926B2 (en) 2002-12-30 2008-11-04 The Regents Of The University Of California Fluid control structures in microfluidic devices
JP2008539090A (ja) * 2005-04-26 2008-11-13 アビザ テクノロジー リミティド マイクロ流体構造およびその製造方法
US8257964B2 (en) * 2006-01-04 2012-09-04 Cell ASIC Microwell cell-culture device and fabrication method
US9410975B2 (en) * 2007-05-15 2016-08-09 Ael Mining Services Limited Pressure manifold to equalize pressure in integration PCR-CE microfluidic devices
ES2453107T3 (es) 2007-06-11 2014-04-04 Wako Pure Chemical Industries, Ltd. Procedimiento de amplificación de ácidos nucleicos usando una PCR sobre microchip con detección integrada de CE en tiempo real
EP4512526A3 (en) * 2008-09-23 2025-06-04 Bio-Rad Laboratories, Inc. Droplet-based assay system
US9157550B2 (en) * 2009-01-05 2015-10-13 The Board Of Trustees Of The University Of Illinois Microfluidic systems and methods
NL2002862C2 (en) * 2009-05-08 2010-11-09 Friesland Brands Bv Microfluidic apparatus and method for generating a dispersion.
WO2011002957A2 (en) * 2009-07-01 2011-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
FR2951153A1 (fr) * 2009-10-09 2011-04-15 Corning Inc Dispositif microfluidique
CA2767182C (en) * 2010-03-25 2020-03-24 Bio-Rad Laboratories, Inc. Droplet generation for droplet-based assays
WO2012007787A1 (en) * 2010-07-15 2012-01-19 Indian Statistical Institute Architectural layout for dilution with reduced wastage in digital microfluidic based lab-on-a-chip
DE102010047384B4 (de) * 2010-10-02 2012-06-28 Karlsruher Institut für Technologie Vorrichtung und Verfahren zur Erzeugung oder zur Ablage eines Fluidstroms aus Fluidsegmenten und ihre Verwendung
EP3574990B1 (en) * 2010-11-01 2022-04-06 Bio-Rad Laboratories, Inc. System for forming emulsions
CN102389730A (zh) * 2011-08-23 2012-03-28 东南大学 一种双重乳液制备芯片
EP2760578B1 (en) 2011-09-28 2020-08-26 President and Fellows of Harvard College Systems and methods for droplet production and/or fluidic manipulation
JP6449266B2 (ja) 2013-06-21 2019-01-09 バイオ−ラッド・ラボラトリーズ・インコーポレーテッド 流体ピックアップを備えるマイクロ流体システム

Similar Documents

Publication Publication Date Title
JP2016528027A5 (https=)
Wang et al. Microflow extraction: A review of recent development
WO2018126082A8 (en) Digital microfluidic devices and methods
JP6449266B2 (ja) 流体ピックアップを備えるマイクロ流体システム
JP2020515815A5 (https=)
USD822225S1 (en) Device for analysis of biological sample
JP2013524171A5 (https=)
WO2009054870A3 (en) Intergrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
JP2012503773A5 (https=)
JP2017518497A5 (https=)
RU2018121723A (ru) Аналитическое устройство
BR112017004191A2 (pt) dispositivo microfluídico, e, método para purificar um analito biológico ou químico.
WO2012159063A3 (en) Gravity flow fluidic device for nucleic acid extraction
WO2016128843A3 (en) Disposable cartridge for sample fluid analysis
CN106573185A8 (zh) 油水分离装置、排水系统
EP3270141A3 (en) Fluidic centripetal device
JP2014176306A5 (https=)
Kim et al. On-site extraction and purification of bacterial nucleic acids from blood samples using an unpowered microfluidic device
WO2019067319A3 (en) Microfluidic technique for detection of multi-contact miscibility
US20180043362A1 (en) Target constituent location and discharge
DE602007003324D1 (de) Zentrifugationsverfahren und Kammer zum Waschen und kontinuierlichen Trennen von Blutbestandteilen
JP2017514145A (ja) 血液などの流体混合物を分離するためのデバイスおよび方法
JP2021536583A5 (https=)
JP2016508025A5 (https=)
GB2568014A (en) Gas-liquid separator for collecting chromatographic fractions