JP2016524127A5 - - Google Patents
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- JP2016524127A5 JP2016524127A5 JP2016506385A JP2016506385A JP2016524127A5 JP 2016524127 A5 JP2016524127 A5 JP 2016524127A5 JP 2016506385 A JP2016506385 A JP 2016506385A JP 2016506385 A JP2016506385 A JP 2016506385A JP 2016524127 A5 JP2016524127 A5 JP 2016524127A5
- Authority
- JP
- Japan
- Prior art keywords
- neuraminidase
- sample
- buffer
- immunoassay
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000005348 Neuraminidase Human genes 0.000 claims 34
- 108010006232 Neuraminidase Proteins 0.000 claims 34
- 238000000034 method Methods 0.000 claims 26
- 238000003018 immunoassay Methods 0.000 claims 16
- 239000000872 buffer Substances 0.000 claims 14
- 230000000694 effects Effects 0.000 claims 12
- 238000003556 assay Methods 0.000 claims 11
- 239000011159 matrix material Substances 0.000 claims 11
- 150000001875 compounds Chemical class 0.000 claims 10
- 208000037797 influenza A Diseases 0.000 claims 9
- 208000037798 influenza B Diseases 0.000 claims 9
- 239000003153 chemical reaction reagent Substances 0.000 claims 8
- 241000712461 unidentified influenza virus Species 0.000 claims 8
- 230000005764 inhibitory process Effects 0.000 claims 7
- 102000004190 Enzymes Human genes 0.000 claims 5
- 108090000790 Enzymes Proteins 0.000 claims 5
- 238000001514 detection method Methods 0.000 claims 5
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 claims 4
- 239000012131 assay buffer Substances 0.000 claims 4
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 4
- 239000003443 antiviral agent Substances 0.000 claims 3
- 230000011664 signaling Effects 0.000 claims 3
- IGXWBGJHJZYPQS-SSDOTTSWSA-N D-Luciferin Chemical compound OC(=O)[C@H]1CSC(C=2SC3=CC=C(O)C=C3N=2)=N1 IGXWBGJHJZYPQS-SSDOTTSWSA-N 0.000 claims 2
- CYCGRDQQIOGCKX-UHFFFAOYSA-N Dehydro-luciferin Natural products OC(=O)C1=CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 CYCGRDQQIOGCKX-UHFFFAOYSA-N 0.000 claims 2
- BJGNCJDXODQBOB-UHFFFAOYSA-N Fivefly Luciferin Natural products OC(=O)C1CSC(C=2SC3=CC(O)=CC=C3N=2)=N1 BJGNCJDXODQBOB-UHFFFAOYSA-N 0.000 claims 2
- QNRRHYPPQFELSF-CNYIRLTGSA-N Laninamivir Chemical compound OC[C@@H](O)[C@@H](OC)[C@@H]1OC(C(O)=O)=C[C@H](N=C(N)N)[C@H]1NC(C)=O QNRRHYPPQFELSF-CNYIRLTGSA-N 0.000 claims 2
- 108060001084 Luciferase Proteins 0.000 claims 2
- 239000005089 Luciferase Substances 0.000 claims 2
- DDWFXDSYGUXRAY-UHFFFAOYSA-N Luciferin Natural products CCc1c(C)c(CC2NC(=O)C(=C2C=C)C)[nH]c1Cc3[nH]c4C(=C5/NC(CC(=O)O)C(C)C5CC(=O)O)CC(=O)c4c3C DDWFXDSYGUXRAY-UHFFFAOYSA-N 0.000 claims 2
- 241000701076 Macacine alphaherpesvirus 1 Species 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- VBZWSGALLODQNC-UHFFFAOYSA-N hexafluoroacetone Chemical compound FC(F)(F)C(=O)C(F)(F)F VBZWSGALLODQNC-UHFFFAOYSA-N 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- 238000007689 inspection Methods 0.000 claims 2
- 229950004244 laninamivir Drugs 0.000 claims 2
- VSZGPKBBMSAYNT-RRFJBIMHSA-N oseltamivir Chemical compound CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1 VSZGPKBBMSAYNT-RRFJBIMHSA-N 0.000 claims 2
- 229960003752 oseltamivir Drugs 0.000 claims 2
- XRQDFNLINLXZLB-CKIKVBCHSA-N peramivir Chemical compound CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@@H](C(O)=O)C[C@H]1NC(N)=N XRQDFNLINLXZLB-CKIKVBCHSA-N 0.000 claims 2
- 229960001084 peramivir Drugs 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 230000035945 sensitivity Effects 0.000 claims 2
- 229960001028 zanamivir Drugs 0.000 claims 2
- ARAIBEBZBOPLMB-UFGQHTETSA-N zanamivir Chemical compound CC(=O)N[C@@H]1[C@@H](N=C(N)N)C=C(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO ARAIBEBZBOPLMB-UFGQHTETSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 241000712431 Influenza A virus Species 0.000 claims 1
- 241000713196 Influenza B virus Species 0.000 claims 1
- 101000874347 Streptococcus agalactiae IgA FC receptor Proteins 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000000840 anti-viral effect Effects 0.000 claims 1
- 230000009977 dual effect Effects 0.000 claims 1
- 238000007824 enzymatic assay Methods 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 238000003239 susceptibility assay Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361807185P | 2013-04-01 | 2013-04-01 | |
| US61/807,185 | 2013-04-01 | ||
| PCT/US2014/032567 WO2014165536A1 (en) | 2013-04-01 | 2014-04-01 | Methods and kits for the diagnosis of influenza |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019169472A Division JP7096219B2 (ja) | 2013-04-01 | 2019-09-18 | インフルエンザ診断のための方法及びキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016524127A JP2016524127A (ja) | 2016-08-12 |
| JP2016524127A5 true JP2016524127A5 (enExample) | 2017-05-18 |
| JP6591398B2 JP6591398B2 (ja) | 2019-10-16 |
Family
ID=50625220
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506385A Active JP6591398B2 (ja) | 2013-04-01 | 2014-04-01 | インフルエンザ診断のための方法及びキット |
| JP2019169472A Active JP7096219B2 (ja) | 2013-04-01 | 2019-09-18 | インフルエンザ診断のための方法及びキット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019169472A Active JP7096219B2 (ja) | 2013-04-01 | 2019-09-18 | インフルエンザ診断のための方法及びキット |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10317404B2 (enExample) |
| EP (1) | EP2981618B1 (enExample) |
| JP (2) | JP6591398B2 (enExample) |
| KR (1) | KR102348484B1 (enExample) |
| CN (2) | CN105264086B (enExample) |
| AU (2) | AU2014248225B2 (enExample) |
| BR (1) | BR112015025042B1 (enExample) |
| CA (1) | CA2908028C (enExample) |
| ES (1) | ES2754402T3 (enExample) |
| RU (1) | RU2713112C2 (enExample) |
| WO (1) | WO2014165536A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6411740B2 (ja) * | 2013-01-15 | 2018-10-24 | 国立大学法人広島大学 | ノイラミニダーゼ活性阻害剤の有効性を判定するための組成物、キットおよびその利用 |
| JP6591398B2 (ja) | 2013-04-01 | 2019-10-16 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | インフルエンザ診断のための方法及びキット |
| US10520498B2 (en) | 2017-03-14 | 2019-12-31 | Becton, Dickinson And Company | Devices and techniques for oral fluid collection and seroprotection testing |
| CN110832083A (zh) * | 2017-07-04 | 2020-02-21 | 卡维迪有限公司 | 用于通过测量酶活性来评估病毒对治疗的敏感性的方法及其系统 |
| WO2019060275A1 (en) | 2017-09-21 | 2019-03-28 | Becton, Dickinson And Company | DEMARCATION TEMPLATE FOR DANGEROUS CONTAMINANT TEST |
| AU2018337030B2 (en) | 2017-09-21 | 2025-04-10 | Becton, Dickinson And Company | Hazardous contaminant collection kit and rapid testing |
| US11360001B2 (en) | 2017-09-21 | 2022-06-14 | Becton, Dickinson And Company | Reactive demarcation template for hazardous contaminant testing |
| CN209400540U (zh) | 2017-09-21 | 2019-09-17 | 贝克顿·迪金森公司 | 危险污染检测系统和收集装置 |
| WO2019060276A1 (en) | 2017-09-21 | 2019-03-28 | Becton, Dickinson And Company | INCREASED REALITY DEVICES FOR DANGEROUS CONTAMINANT TESTING |
| CN209400423U (zh) * | 2017-09-21 | 2019-09-17 | 贝克顿·迪金森公司 | 横向流测定物、测定物读取器装置和包括其的系统 |
| AU2018337028B2 (en) * | 2017-09-21 | 2025-05-08 | Becton, Dickinson And Company | Sampling systems and techniques to collect hazardous contaminants with high pickup and shedding efficiencies |
| CN111741951B (zh) * | 2018-03-02 | 2023-08-18 | 日本农药株式会社 | 酰胺化合物或其盐类、以及含有这些化合物的农业园艺用杀菌剂及其使用方法 |
| KR102129937B1 (ko) * | 2018-07-31 | 2020-07-03 | 재단법인 아산사회복지재단 | 종이기반 핵산검출용 키트 및 pcr 증폭산물을 분석하기 위한 방법 |
| EP3774841A1 (en) | 2018-08-27 | 2021-02-17 | Regeneron Pharmaceuticals, Inc. | Use of raman spectroscopy in downstream purification |
| CN212748381U (zh) | 2019-01-28 | 2021-03-19 | 贝克顿·迪金森公司 | 一种有害污染物检测系统和一种有害污染物收集装置 |
| JPWO2020196295A1 (enExample) * | 2019-03-25 | 2020-10-01 | ||
| KR20230048505A (ko) * | 2020-06-15 | 2023-04-11 | 뉴옴 펩타이즈 피티이. 엘티디. | 분석물의 검출을 위한 측면 유동 검정 장치 및 이의 검출 방법 |
| JP2022018768A (ja) * | 2020-07-16 | 2022-01-27 | デンカ株式会社 | 簡易鼻腔粘膜表面付着粘液の採取方法および該検体中の被検出物を検出するための検査キット |
| KR20220060269A (ko) | 2020-11-04 | 2022-05-11 | 인텔로스 주식회사 | 코로나 바이러스 감염증 및 인플루엔자 바이러스 감염증 동시 진단키트 |
| KR102265441B1 (ko) * | 2020-12-23 | 2021-06-15 | 충남대학교 산학협력단 | 화학 발광 기반의 조류 인플루엔자 바이러스 검출용 조성물 및 이의 용도 |
| CN115015541A (zh) | 2021-03-05 | 2022-09-06 | 全球诊断系统受益有限责任公司 | 带流体贮存器的诊断装置及相关方法和试剂盒 |
| JP2023016529A (ja) * | 2021-07-21 | 2023-02-02 | 東洋紡株式会社 | イムノクロマト試験片 |
| JP2023016530A (ja) * | 2021-07-21 | 2023-02-02 | 東洋紡株式会社 | イムノクロマト試験片 |
| US20250066867A1 (en) * | 2023-08-23 | 2025-02-27 | Vedabio, Inc. | Rapid detection of known and emerging influenza viruses |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4590169A (en) | 1983-11-18 | 1986-05-20 | Beckman Instruments, Inc. | Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations |
| US4810631A (en) | 1986-05-12 | 1989-03-07 | Becton, Dickinson And Company | Signal enhancement in immunoassay by modulation of chemical catalysis |
| US4835099A (en) | 1986-11-20 | 1989-05-30 | Becton, Dickinson And Company | Signal enhancement in immunoassay by modulation of enzymatic catalysis |
| US5017473A (en) | 1987-05-26 | 1991-05-21 | Becton, Dickinson And Company | Homogeneous chemiluminescence immunoassay using a light absorbing material |
| US4904583A (en) | 1987-05-26 | 1990-02-27 | Becton, Dickinson And Company | Cascade immunoassay by multiple binding reactions |
| CA2000678A1 (en) * | 1988-11-17 | 1990-05-17 | John E. Reardon | Chromogenic substrate for esterase and immunoassay using same |
| CA2072368C (en) | 1989-12-29 | 1998-06-30 | Gregory A. Turner | Methods for diagnosing human influenza and 4-position modified chromogenic n-acetylneuraminic acid substrates for use therein |
| US5314801A (en) | 1992-11-06 | 1994-05-24 | Becton, Dickinson And Company | Probes to Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium paratuberculosis |
| US5470723A (en) | 1993-05-05 | 1995-11-28 | Becton, Dickinson And Company | Detection of mycobacteria by multiplex nucleic acid amplification |
| US5457027A (en) | 1993-05-05 | 1995-10-10 | Becton, Dickinson And Company | Internal controls for isothermal nucleic acid amplification reactions |
| US5518884A (en) | 1994-02-28 | 1996-05-21 | Becton, Dickinson And Company | Nucleic acid sequences specific for mycbacterium kansasii |
| US5639428A (en) | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
| US5998221A (en) | 1996-09-25 | 1999-12-07 | Becton, Dickinson And Company | Non-instrumented assay with quantitative and qualitative results |
| US5719020A (en) * | 1996-09-25 | 1998-02-17 | Oklahoma Medical Research Foundation | 4,7-dialkoxy N-acetylneuraminic acid derivatives and methods for detection of influenza type A and B viruses in clinical specimens |
| US6194220B1 (en) | 1996-09-25 | 2001-02-27 | Becton, Dickinson And Company | Non-instrumented assay with quantitative and qualitative results |
| TR199901081T2 (xx) | 1996-11-14 | 1999-08-23 | Biota Scientific Management Pty.Ltd. | Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler. |
| CA2314431A1 (en) * | 1997-12-18 | 1999-06-24 | Sepracor Inc. | Screening assays for the detection and diagnosis of influenza virus |
| US6267722B1 (en) | 1998-02-03 | 2001-07-31 | Adeza Biomedical Corporation | Point of care diagnostic systems |
| US6394952B1 (en) | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
| US6303764B1 (en) | 1998-09-24 | 2001-10-16 | Zymetx, Inc. | Synthesis of 4,7-dialkyl chromogenic glycosides of N-acetylneuraminic acids |
| WO2000063423A2 (en) | 1999-04-16 | 2000-10-26 | Zymetx, Inc. | Viral detection method using viral encoded enzymes and chemiluminescent substrates |
| US6420552B1 (en) | 1999-09-10 | 2002-07-16 | Zymetx, Inc. | Syntheses of 4-alkyl chromogenic glycosides and 7-alkyl chromogenic glycosides of N-acetylneuraminic acids |
| EP1253203A1 (en) | 2001-04-25 | 2002-10-30 | Becton Dickinson and Company | Rapid resuscitation, growth, capture and detection of microorganisms |
| AU2004235349B2 (en) | 2003-04-25 | 2009-11-19 | Becton, Dickinson And Company | Detection of herpes simplex virus types 1 and 2 by nucleic acid amplification |
| US7595152B2 (en) | 2005-07-01 | 2009-09-29 | Arbor Vita Corporation | Detection of influenza virus |
| WO2007053487A2 (en) | 2005-10-28 | 2007-05-10 | Binax, Inc. | Methods and devices for detection of the strain of a pathogen |
| US8163237B2 (en) | 2006-05-08 | 2012-04-24 | Becton, Dickinson And Company | Vascular access device pathogenic status indication |
| US8007999B2 (en) * | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
| WO2007135099A1 (en) | 2006-05-18 | 2007-11-29 | Veterinärmedizinische Universität Wien | Detection method for influenza viruses |
| JP2008014751A (ja) | 2006-07-05 | 2008-01-24 | Denka Seiken Co Ltd | 着色ラテックス粒子を用いるメンブレンアッセイ法およびキット |
| JP5300200B2 (ja) * | 2006-08-31 | 2013-09-25 | 大阪府 | トリインフルエンザウイルスに特異的な迅速診断法 |
| CA2684998A1 (en) * | 2007-04-30 | 2009-01-29 | Nanogen, Inc. | Multianalyte assay |
| US7893272B2 (en) * | 2007-05-15 | 2011-02-22 | Cellex, Inc. | Reagents and kits for detection of influenza virus and the like |
| US8163474B2 (en) * | 2008-03-15 | 2012-04-24 | Arbor Vita Corporation | NS1-NP diagnostics of influenza virus infection |
| WO2010139047A1 (en) * | 2009-06-01 | 2010-12-09 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health | Reagents and methods for detecting influenza virus proteins |
| JP6591398B2 (ja) | 2013-04-01 | 2019-10-16 | ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ | インフルエンザ診断のための方法及びキット |
-
2014
- 2014-04-01 JP JP2016506385A patent/JP6591398B2/ja active Active
- 2014-04-01 WO PCT/US2014/032567 patent/WO2014165536A1/en not_active Ceased
- 2014-04-01 EP EP14720452.3A patent/EP2981618B1/en active Active
- 2014-04-01 KR KR1020157031383A patent/KR102348484B1/ko not_active Expired - Fee Related
- 2014-04-01 US US14/781,008 patent/US10317404B2/en active Active
- 2014-04-01 ES ES14720452T patent/ES2754402T3/es active Active
- 2014-04-01 CN CN201480031254.8A patent/CN105264086B/zh active Active
- 2014-04-01 BR BR112015025042-4A patent/BR112015025042B1/pt active IP Right Grant
- 2014-04-01 CA CA2908028A patent/CA2908028C/en active Active
- 2014-04-01 CN CN201810491986.5A patent/CN108663518B/zh active Active
- 2014-04-01 RU RU2015141509A patent/RU2713112C2/ru active
- 2014-04-01 AU AU2014248225A patent/AU2014248225B2/en active Active
-
2019
- 2019-04-15 US US16/384,020 patent/US11209433B2/en active Active
- 2019-09-18 JP JP2019169472A patent/JP7096219B2/ja active Active
-
2020
- 2020-08-31 AU AU2020227005A patent/AU2020227005B2/en active Active
-
2021
- 2021-11-16 US US17/527,524 patent/US12372525B2/en active Active
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