JP2016521747A - 貧血治療のための組成物及び方法 - Google Patents

貧血治療のための組成物及び方法 Download PDF

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Publication number
JP2016521747A
JP2016521747A JP2016519543A JP2016519543A JP2016521747A JP 2016521747 A JP2016521747 A JP 2016521747A JP 2016519543 A JP2016519543 A JP 2016519543A JP 2016519543 A JP2016519543 A JP 2016519543A JP 2016521747 A JP2016521747 A JP 2016521747A
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compound
formula
anemia
patient
level
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JP2016519543A
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Japanese (ja)
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JP2016521747A5 (enExample
Inventor
シャルウィツ ロバート
シャルウィツ ロバート
ハートマン シャルロッテ
ハートマン シャルロッテ
ブク アクシャイ
ブク アクシャイ
シャルウィツ イサイア
シャルウィツ イサイア
ジャヌスズ ジョン
ジャヌスズ ジョン
ガードナー ジョセフ
ガードナー ジョセフ
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Akebia Therapeutics Inc
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Akebia Therapeutics Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52022903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2016521747(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akebia Therapeutics Inc filed Critical Akebia Therapeutics Inc
Publication of JP2016521747A publication Critical patent/JP2016521747A/ja
Publication of JP2016521747A5 publication Critical patent/JP2016521747A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2016519543A 2013-06-13 2014-06-04 貧血治療のための組成物及び方法 Pending JP2016521747A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361834808P 2013-06-13 2013-06-13
US61/834,808 2013-06-13
US201361889478P 2013-10-10 2013-10-10
US61/889,478 2013-10-10
US201361898890P 2013-11-01 2013-11-01
US201361898885P 2013-11-01 2013-11-01
US61/898,885 2013-11-01
US61/898,890 2013-11-01
US201361912185P 2013-12-05 2013-12-05
US61/912,185 2013-12-05
PCT/US2014/040889 WO2014200773A2 (en) 2013-06-13 2014-06-04 Compositions and methods for treating anemia

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019091113A Division JP6612479B2 (ja) 2013-06-13 2019-05-14 貧血治療のための組成物及び方法

Publications (2)

Publication Number Publication Date
JP2016521747A true JP2016521747A (ja) 2016-07-25
JP2016521747A5 JP2016521747A5 (enExample) 2018-11-22

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Family Applications (6)

Application Number Title Priority Date Filing Date
JP2016519543A Pending JP2016521747A (ja) 2013-06-13 2014-06-04 貧血治療のための組成物及び方法
JP2019091113A Active JP6612479B2 (ja) 2013-06-13 2019-05-14 貧血治療のための組成物及び方法
JP2019197138A Active JP6937812B2 (ja) 2013-06-13 2019-10-30 貧血治療のための組成物及び方法
JP2021140772A Active JP7328291B2 (ja) 2013-06-13 2021-08-31 貧血治療のための組成物及び方法
JP2023127201A Active JP7672455B2 (ja) 2013-06-13 2023-08-03 貧血治療のための組成物及び方法
JP2025070412A Pending JP2025114609A (ja) 2013-06-13 2025-04-22 貧血治療のための組成物及び方法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2019091113A Active JP6612479B2 (ja) 2013-06-13 2019-05-14 貧血治療のための組成物及び方法
JP2019197138A Active JP6937812B2 (ja) 2013-06-13 2019-10-30 貧血治療のための組成物及び方法
JP2021140772A Active JP7328291B2 (ja) 2013-06-13 2021-08-31 貧血治療のための組成物及び方法
JP2023127201A Active JP7672455B2 (ja) 2013-06-13 2023-08-03 貧血治療のための組成物及び方法
JP2025070412A Pending JP2025114609A (ja) 2013-06-13 2025-04-22 貧血治療のための組成物及び方法

Country Status (37)

Country Link
US (2) US11857543B2 (enExample)
EP (2) EP3007695B1 (enExample)
JP (6) JP2016521747A (enExample)
KR (4) KR102461176B1 (enExample)
CN (3) CN114404413A (enExample)
AU (4) AU2014278543B2 (enExample)
BR (1) BR112015031027A2 (enExample)
CA (2) CA3151685A1 (enExample)
CL (2) CL2015003602A1 (enExample)
CY (2) CY1126699T1 (enExample)
DK (1) DK3007695T3 (enExample)
DO (1) DOP2015000297A (enExample)
EC (1) ECSP20058592A (enExample)
ES (1) ES2974273T3 (enExample)
FI (2) FI3007695T3 (enExample)
FR (1) FR24C1025I2 (enExample)
HR (1) HRP20240319T1 (enExample)
HU (2) HUE066123T2 (enExample)
IL (3) IL243047B (enExample)
LT (2) LT3007695T (enExample)
MX (3) MX378150B (enExample)
MY (1) MY204336A (enExample)
NL (1) NL301278I2 (enExample)
NO (1) NO2024025I1 (enExample)
NZ (3) NZ753904A (enExample)
PE (2) PE20201496A1 (enExample)
PH (2) PH12015502738B1 (enExample)
PL (1) PL3007695T3 (enExample)
PT (1) PT3007695T (enExample)
RS (1) RS65341B1 (enExample)
RU (2) RU2019134558A (enExample)
SG (2) SG11201509998WA (enExample)
SI (1) SI3007695T1 (enExample)
SM (1) SMT202400092T1 (enExample)
TW (5) TWI856464B (enExample)
WO (1) WO2014200773A2 (enExample)
ZA (1) ZA201509024B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023518392A (ja) * 2020-03-17 2023-05-01 ザイダス ライフサイエンシズ リミティド Ｈｉｆプロリルヒドロキシラーゼ阻害剤を含む製剤組成物
JP2024503377A (ja) * 2021-01-08 2024-01-25 アケビア セラピューティクス インコーポレイテッド バダデュスタットを使用した治療方法

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ATE485264T1 (de) 2006-06-26 2010-11-15 Warner Chilcott Co Llc Prolylhydroxylase-hemmer und verfahren zu ihrer anwendung
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WO2014170832A1 (en) 2013-04-16 2014-10-23 Koninklijke Philips N.V. System and method for biventricular pacemaker pulse detection in surface ecg
HUE066123T2 (hu) 2013-06-13 2024-07-28 Akebia Therapeutics Inc Készítmények és módszerek anémia kezelésére
AU2014348523B2 (en) 2013-11-15 2019-01-03 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
CA2974691A1 (en) 2015-01-23 2016-07-28 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
MX374909B (es) * 2015-04-01 2025-03-06 Akebia Therapeutics Inc El uso del inhibidor de propil hidrolasa del factor inducible de hipoxia (hif) para el tratamiento o prevención de la anemia.
CN108401429A (zh) * 2016-12-06 2018-08-14 深圳市塔吉瑞生物医药有限公司 一种取代的杂芳基酰胺化合物及包含该化合物的组合物及其用途
WO2019028150A1 (en) * 2017-08-01 2019-02-07 Akebia Therapeutics, Inc. COMPOSITIONS FOR USE IN METHODS OF TREATING HEMOGLOBINOPATHIES
IL278533B1 (en) 2018-05-09 2025-10-01 Akebia Therapeutics Inc Process for the preparation of 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
PH12022551040A1 (en) * 2019-10-31 2023-05-29 Akebia Therapeutics Inc Therapeutic methods using vadadustat
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid
AU2021263829A1 (en) * 2020-04-29 2022-12-15 BioAge Labs, Inc. Hypoxia-inducible factor prolyl hydroxylase inhibitors for treating aging-related conditions
JP2023530452A (ja) 2020-06-19 2023-07-18 アケビア セラピューティクス インコーポレイテッド バダデュスタットの薬物間相互作用の調節
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
IL305487A (en) 2021-03-01 2023-10-01 Akebia Therapeutics Inc Modulation of drug-drug interactions by VADADUSTAT

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