JP2016520621A5 - - Google Patents

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Publication number
JP2016520621A5
JP2016520621A5 JP2016517067A JP2016517067A JP2016520621A5 JP 2016520621 A5 JP2016520621 A5 JP 2016520621A5 JP 2016517067 A JP2016517067 A JP 2016517067A JP 2016517067 A JP2016517067 A JP 2016517067A JP 2016520621 A5 JP2016520621 A5 JP 2016520621A5
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JP
Japan
Prior art keywords
alkyl
item
group
formula
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016517067A
Other languages
English (en)
Japanese (ja)
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JP2016520621A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/040387 external-priority patent/WO2014194292A1/en
Publication of JP2016520621A publication Critical patent/JP2016520621A/ja
Publication of JP2016520621A5 publication Critical patent/JP2016520621A5/ja
Pending legal-status Critical Current

Links

JP2016517067A 2013-05-31 2014-05-30 酸化ストレス障害の処置のためのカルボン酸誘導体 Pending JP2016520621A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361829886P 2013-05-31 2013-05-31
US61/829,886 2013-05-31
PCT/US2014/040387 WO2014194292A1 (en) 2013-05-31 2014-05-30 Carboxylic acid derivatives for treatment of oxidative stress disorders

Publications (2)

Publication Number Publication Date
JP2016520621A JP2016520621A (ja) 2016-07-14
JP2016520621A5 true JP2016520621A5 (enExample) 2017-07-06

Family

ID=50983236

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016517067A Pending JP2016520621A (ja) 2013-05-31 2014-05-30 酸化ストレス障害の処置のためのカルボン酸誘導体

Country Status (8)

Country Link
US (1) US20160115141A1 (enExample)
EP (1) EP3004071A1 (enExample)
JP (1) JP2016520621A (enExample)
AU (1) AU2014273891A1 (enExample)
CA (1) CA2912871A1 (enExample)
HK (1) HK1223369A1 (enExample)
MX (1) MX2015016014A (enExample)
WO (1) WO2014194292A1 (enExample)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
ES2714900T3 (es) 2005-06-01 2019-05-30 Bioelectron Tech Corp Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos
WO2007100652A2 (en) 2006-02-22 2007-09-07 Edison Pharmaceuticals, Inc. Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
SI3456707T1 (sl) 2007-11-06 2020-10-30 Ptc Therapeutics, Inc. Derivati 4-(P-kuinonil)-2-hidroksibutanamida za zdravljenje mitohondrijske bolezni
WO2009089224A1 (en) 2008-01-08 2009-07-16 Edison Pharmaceuticals, Inc. (HET) ARYL-p-QUINONE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES
JP2012502064A (ja) 2008-09-10 2012-01-26 エジソン ファーマシューティカルズ, インコーポレイテッド 酸化還元活性治療剤を用いての広汎性発達障害の処置
MY157119A (en) 2008-10-28 2016-05-13 Edison Pharmaceuticals Inc Process for the production of alpha-tocotrienol and derivatives
HUE037574T2 (hu) 2009-04-28 2018-09-28 Bioelectron Tech Corp Leber-féle örökletes optikus neuropátia és domináns optikus atrofia kezelése tokotrienol kinonokkal
WO2012174286A1 (en) 2011-06-14 2012-12-20 Edison Pharmaceuticals, Inc. Catechol derivatives for treatment of oxidative stress diseases
JP2014520894A (ja) 2011-07-19 2014-08-25 エジソン ファーマシューティカルズ, インコーポレイテッド 非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法
CA2883882A1 (en) 2012-09-07 2014-03-13 Edison Pharmaceuticals, Inc. Benzoquinone derivatives for treating oxidative stress disorders
US9670170B2 (en) 2013-03-15 2017-06-06 Bioelectron Technology Corporation Resorufin derivatives for treatment of oxidative stress disorders
CA2906145A1 (en) 2013-03-15 2014-09-18 Edison Pharmaceuticals, Inc. Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders
US9868711B2 (en) 2013-03-15 2018-01-16 Bioelectron Technology Corporation Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
WO2016100579A1 (en) 2014-12-16 2016-06-23 Edison Pharmaceuticals, Inc., Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
CN107708711A (zh) * 2015-05-22 2018-02-16 艾尔牛奶有限公司 β‑酪蛋白A2和抗氧化能力
WO2017060432A1 (en) * 2015-10-08 2017-04-13 Khondrion Ip B.V. Novel compounds for treating mitochondrial disease
JP7117241B2 (ja) 2015-12-16 2022-08-12 ピーティーシー セラピューティクス, インコーポレイテッド 混合されたトコール組成物からアルファ-トコトリエノールを富化するための改良された方法
EP3389646A1 (en) 2015-12-17 2018-10-24 BioElectron Technology Corporation Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
WO2018093957A1 (en) * 2016-11-15 2018-05-24 Bioelectron Technology Corporation 2-substituted amino-naphth[1,2-d]imidazol-5-one compounds or pharmaceutically acceptable salts thereof cross reference to related applications
JP2018083799A (ja) 2016-11-15 2018-05-31 バイオエレクトロン テクノロジー コーポレイション 2−置換アミノ−ナフト[1,2−d]イミダゾール−5−オン化合物またはその製薬学上許容される塩
KR102742339B1 (ko) 2017-04-21 2024-12-13 유니버시티 오브 타스마니아 치료 화합물 및 방법
JP7412177B2 (ja) * 2018-02-19 2024-01-12 國子 草間 バレロラクトン(Valerolactone)系新規化合物、及び、医薬
FI3866772T3 (fi) 2018-10-17 2024-01-11 Ptc Therapeutics Inc 2,3,5-trimetyyli-6-nonyylisykloheksa-2,5-dieeni-1,4-dioni alfa-synukleinopatioiden, tauopatioiden ja muiden häiriöiden estämiseen ja hoitoon
CN118175991A (zh) 2021-07-08 2024-06-11 Ptc医疗公司 包含2,3,5-三甲基-6-壬基环己-2,5-二烯-1,4-二酮的药物组合物

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
JPS5621021B2 (enExample) * 1973-12-19 1981-05-16
JPS5640651A (en) * 1979-09-12 1981-04-16 Takeda Chem Ind Ltd Quinone compound and its preparation
JPH07316049A (ja) * 1994-05-25 1995-12-05 Nippon Oil & Fats Co Ltd 細胞傷害防御剤
US6150402A (en) * 1994-08-15 2000-11-21 Loma Linda University Medical Center Natriuretic compounds
NZ513547A (en) 2001-08-13 2002-09-27 Antipodean Biotechnology Ltd Synthesis of triphenylphosphonium quinols (e.g. mitoquinol) and/or quinones (e.g. mitoquinone)
GB0204232D0 (en) 2002-02-22 2002-04-10 Isis Innovation Assay
DE60211875T2 (de) 2002-07-01 2006-10-26 Santhera Pharmaceuticals (Schweiz) Ag Screeningverfahren und Verbindungen zur Behandlung von Friedreich ataxia
ES2714900T3 (es) 2005-06-01 2019-05-30 Bioelectron Tech Corp Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos
CA2883882A1 (en) 2012-09-07 2014-03-13 Edison Pharmaceuticals, Inc. Benzoquinone derivatives for treating oxidative stress disorders

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