JP2016520594A5 - - Google Patents

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Publication number
JP2016520594A5
JP2016520594A5 JP2016515131A JP2016515131A JP2016520594A5 JP 2016520594 A5 JP2016520594 A5 JP 2016520594A5 JP 2016515131 A JP2016515131 A JP 2016515131A JP 2016515131 A JP2016515131 A JP 2016515131A JP 2016520594 A5 JP2016520594 A5 JP 2016520594A5
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JP
Japan
Prior art keywords
antibody
fragment
composition
combination
disorder
Prior art date
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Application number
JP2016515131A
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English (en)
Japanese (ja)
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JP2016520594A (ja
JP6587609B2 (ja
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Priority claimed from PCT/US2014/039437 external-priority patent/WO2014190316A1/en
Publication of JP2016520594A publication Critical patent/JP2016520594A/ja
Publication of JP2016520594A5 publication Critical patent/JP2016520594A5/ja
Application granted granted Critical
Publication of JP6587609B2 publication Critical patent/JP6587609B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2016515131A 2013-05-23 2014-05-23 強皮症治療のための抗ccl2及び抗loxl2併用療法 Active JP6587609B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361826692P 2013-05-23 2013-05-23
US61/826,692 2013-05-23
PCT/US2014/039437 WO2014190316A1 (en) 2013-05-23 2014-05-23 Anti-ccl2 and anti-loxl2 combination therapy for treatment of scleroderma

Publications (3)

Publication Number Publication Date
JP2016520594A JP2016520594A (ja) 2016-07-14
JP2016520594A5 true JP2016520594A5 (https=) 2017-06-29
JP6587609B2 JP6587609B2 (ja) 2019-10-09

Family

ID=50983195

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016515131A Active JP6587609B2 (ja) 2013-05-23 2014-05-23 強皮症治療のための抗ccl2及び抗loxl2併用療法

Country Status (11)

Country Link
US (1) US11059906B2 (https=)
EP (1) EP2999484B1 (https=)
JP (1) JP6587609B2 (https=)
CN (1) CN105358175B (https=)
AU (2) AU2014268316B2 (https=)
BR (1) BR112015029300A2 (https=)
CA (1) CA2912443A1 (https=)
EA (1) EA201591993A1 (https=)
HK (1) HK1224174A1 (https=)
MX (1) MX371412B (https=)
WO (1) WO2014190316A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3458157A4 (en) * 2016-05-19 2020-05-27 Momenta Pharmaceuticals, Inc. METHOD FOR TREATING DISEASES RELATING TO FIBROSE AND SYSTEMIC Sclerosis
WO2018106945A1 (en) 2016-12-07 2018-06-14 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
EP3554541B1 (en) 2016-12-14 2023-06-07 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor
CN107794267B (zh) * 2017-03-14 2021-03-26 湖南大学 一种靶向pd1-pdl1的双特异性核酸适体及其衍生物
EP3883635A1 (en) 2018-11-19 2021-09-29 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
KR20210151945A (ko) 2019-04-12 2021-12-14 립타이드 바이오사이언스, 인코포레이티드 대식세포 활성을 조정하기 위한 방법
CN110767262B (zh) * 2019-09-18 2021-02-26 复旦大学 一种基于结构的核酸适配体优化设计方法
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
AU2020403913B2 (en) 2019-12-18 2024-10-10 F. Hoffmann-La Roche Ag Bispecific anti-CCL2 antibodies
AU2022295067A1 (en) * 2021-06-18 2023-12-21 F. Hoffmann-La Roche Ag Bispecific anti-ccl2 antibodies
WO2023097111A2 (en) * 2021-11-29 2023-06-01 Riptide Bioscience, Inc. Methods and compositions for treating calcinosis associated conditions

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US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5132405A (en) 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5091513A (en) 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
JPS6412935A (en) 1987-07-02 1989-01-17 Mitsubishi Electric Corp Constant-speed travel device for vehicle
US6010902A (en) 1988-04-04 2000-01-04 Bristol-Meyers Squibb Company Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
US5601819A (en) 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
DE3909708A1 (de) 1989-03-23 1990-09-27 Boehringer Mannheim Gmbh Verfahren zur herstellung bispezifischer antikoerper
EP0438803B1 (en) 1990-01-26 1997-03-12 Immunomedics, Inc. Vaccines against cancer and infectious diseases
DE4118120A1 (de) 1991-06-03 1992-12-10 Behringwerke Ag Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
US6004555A (en) 1992-03-05 1999-12-21 Board Of Regents, The University Of Texas System Methods for the specific coagulation of vasculature
WO1994008038A1 (en) 1992-10-02 1994-04-14 Trustees Of Dartmouth College Bispecific reagents for redirected targeting of low density lipoprotein
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US20020025317A1 (en) 2000-07-20 2002-02-28 Schering Ag Bispecific monoclonal antibodies to IL-12 and IL-18
AR037456A1 (es) * 2001-11-30 2004-11-10 Biogen Inc Anticuerpos contra proteinas quimiotacticas monocitarias
ES2700141T3 (es) * 2007-08-02 2019-02-14 Gilead Biologics Inc Anticuerpos inhibidores LOXL2 y usos de los mismos
EP2470671B1 (en) 2009-08-28 2014-12-24 Regeneron Pharmaceuticals, Inc. Antikine antibodies that bind to multiple cc chemokines
BR112012019693A2 (pt) * 2010-02-04 2017-06-20 Gilead Biologics Inc anticorpos que se ligam à lisil oxidase-like 2 (loxl2) e métodos de uso para eles.
US20150158942A1 (en) * 2012-05-22 2015-06-11 Shire Human Genetic Therapies, Inc. Anti-ccl2 antibodies for treatment of scleroderma

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