JP2016516072A - 低z原子による腸管ct造影材料 - Google Patents
低z原子による腸管ct造影材料 Download PDFInfo
- Publication number
- JP2016516072A JP2016516072A JP2016503369A JP2016503369A JP2016516072A JP 2016516072 A JP2016516072 A JP 2016516072A JP 2016503369 A JP2016503369 A JP 2016503369A JP 2016503369 A JP2016503369 A JP 2016503369A JP 2016516072 A JP2016516072 A JP 2016516072A
- Authority
- JP
- Japan
- Prior art keywords
- contrast
- contrast medium
- enteric
- formulation
- intestinal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
- A61K49/0414—Particles, beads, capsules or spheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
- A61K49/0414—Particles, beads, capsules or spheres
- A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- High Energy & Nuclear Physics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790734P | 2013-03-15 | 2013-03-15 | |
| US201361798392P | 2013-03-15 | 2013-03-15 | |
| US61/798,392 | 2013-03-15 | ||
| US61/790,734 | 2013-03-15 | ||
| PCT/US2014/030295 WO2014145509A1 (en) | 2013-03-15 | 2014-03-17 | Enteric ct contrast material based on low-z atoms |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018038401A Division JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低z原子による腸管ct造影材料 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016516072A true JP2016516072A (ja) | 2016-06-02 |
| JP2016516072A5 JP2016516072A5 (enExample) | 2017-04-20 |
Family
ID=51530440
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016503369A Pending JP2016516072A (ja) | 2013-03-15 | 2014-03-17 | 低z原子による腸管ct造影材料 |
| JP2018038401A Active JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低z原子による腸管ct造影材料 |
| JP2020144080A Pending JP2020193223A (ja) | 2013-03-15 | 2020-08-28 | 低z原子による腸管ct造影材料 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018038401A Active JP6843787B2 (ja) | 2013-03-15 | 2018-03-05 | 低z原子による腸管ct造影材料 |
| JP2020144080A Pending JP2020193223A (ja) | 2013-03-15 | 2020-08-28 | 低z原子による腸管ct造影材料 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11033640B2 (enExample) |
| EP (2) | EP3984560A1 (enExample) |
| JP (3) | JP2016516072A (enExample) |
| CN (2) | CN105142680A (enExample) |
| ES (1) | ES2897624T3 (enExample) |
| WO (1) | WO2014145509A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11033640B2 (en) | 2013-03-15 | 2021-06-15 | The Regents Of The University Of California | Enteric CT contrast material based on low-z atoms |
| CN107847445B (zh) | 2015-04-20 | 2021-07-20 | 加利福尼亚大学董事会 | 包封的气体或部分真空ct造影材料 |
| US20200179539A1 (en) * | 2016-06-22 | 2020-06-11 | Board Of Regents, The University Of Texas System | Contrast Agents and Methods of Making the Same for Spectral CT That Exhibit Cloaking and Auto-Segmentation |
| US11590225B2 (en) | 2016-12-08 | 2023-02-28 | The Brigham And Women's Hospital, Inc. | Bismuth-gadolinium nanoparticles |
| CN109100775B (zh) * | 2018-07-06 | 2020-05-29 | 郑州云海信息技术有限公司 | 一种双层探测器的能量谱校正方法与装置 |
| JP2020103571A (ja) * | 2018-12-27 | 2020-07-09 | キヤノンメディカルシステムズ株式会社 | 医用処理装置及びx線診断システム |
| JP2024518164A (ja) * | 2021-05-05 | 2024-04-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 低x線減弱度変化ハードシェル経口造影材料 |
| WO2024086131A1 (en) * | 2022-10-18 | 2024-04-25 | The Johns Hopkins University | Systems and methods for angiography using multi-energy detectors |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592185A (en) * | 1967-04-18 | 1971-07-13 | Yeda Res & Dev | Ferromagnetic contrast media and method of use |
| JPS63255237A (ja) * | 1987-03-24 | 1988-10-21 | シリカ・ゲル・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・アドゾルプチオンス‐テヒニーク・アパラーテバウ | 生理学的に認容される超常磁性液体組成物,その製造方法並びにそれよりなる画像形成nmr,x線及び超音波診断剤 |
| JPH07509716A (ja) * | 1992-08-07 | 1995-10-26 | ユニヴァーシティ オブ フロリダ | アーティファクトの無い画像コントラスト増強剤 |
| JP2003160512A (ja) * | 1991-04-05 | 2003-06-03 | Imarx Pharmaceut Corp | 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用 |
| US20070258907A1 (en) * | 2006-04-24 | 2007-11-08 | Davis Mark E | Polymer-coated paramagnetic particles |
| EP2127682A1 (en) * | 2008-05-28 | 2009-12-02 | Deutsches Krebsforschungszentrum | X-ray contrast agent based on bismuth oxide-nanoparticles |
| WO2012080260A1 (en) * | 2010-12-13 | 2012-06-21 | Novartis Ag | Dimeric iap inhibitors |
| WO2012101524A2 (en) * | 2011-01-28 | 2012-08-02 | Dalhousie University | Radiopaque embolic particles |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4615879A (en) * | 1983-11-14 | 1986-10-07 | Vanderbilt University | Particulate NMR contrast agents for gastrointestinal application |
| JPS6238172A (ja) | 1985-08-12 | 1987-02-19 | 株式会社 高研 | 抗血栓性医用材料の製造方法 |
| IL82834A (en) | 1987-06-09 | 1990-11-05 | Yissum Res Dev Co | Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom |
| GB9006671D0 (en) | 1990-03-24 | 1990-05-23 | Univ Manchester | Diagnostic method and compositions |
| SE9101709L (sv) * | 1991-06-03 | 1992-12-04 | Karlshamns Lipidteknik Ab | Lipidderivat som diagnostikum eller kontrastmedel |
| US5472682A (en) | 1993-03-31 | 1995-12-05 | Sterling Winthrop Inc. | Compositions of iodophenyl esters and iodophenyl sulfonates and pharmaceutically acceptable clays for visualization of the gastrointestinal tract |
| US5318769A (en) | 1993-03-31 | 1994-06-07 | Sterling Winthrop Inc. | Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract |
| WO1995022995A1 (en) | 1994-02-25 | 1995-08-31 | Nycomed Imaging A/S | X-ray contrast compositions containing cellulose derivatives |
| CN1147206A (zh) | 1994-04-21 | 1997-04-09 | 耐克麦德英梅金公司 | 含有药用粘土的x-射线造影组合物 |
| US5736121A (en) | 1994-05-23 | 1998-04-07 | Imarx Pharmaceutical Corp. | Stabilized homogenous suspensions as computed tomography contrast agents |
| US6818199B1 (en) * | 1994-07-29 | 2004-11-16 | James F. Hainfeld | Media and methods for enhanced medical imaging |
| US5580579A (en) * | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
| GB9603547D0 (en) | 1996-02-20 | 1996-04-17 | Nycomed Imaging As | Contrast media |
| CN1221250C (zh) * | 1998-04-09 | 2005-10-05 | 阿莫萨姆保健公司 | 微粒造影剂在研究生理参数的诊断成像中的应用 |
| NO20052429D0 (no) * | 2005-05-20 | 2005-05-20 | Amersham Health As | Konstrastmidler |
| GB0519391D0 (en) | 2005-09-22 | 2005-11-02 | Aion Diagnostics Ltd | Imaging agents |
| EP2651456A1 (en) | 2010-12-15 | 2013-10-23 | General Electric Company | Nanoparticle composition and associated methods thereof |
| US10071174B2 (en) | 2011-06-06 | 2018-09-11 | Portland State University | Bismuth particle X-ray contrast agents |
| WO2013184061A1 (en) | 2012-06-04 | 2013-12-12 | Migrata U.K. Limited | Medical use of particles of titanium and/or titanium oxide |
| US11033640B2 (en) | 2013-03-15 | 2021-06-15 | The Regents Of The University Of California | Enteric CT contrast material based on low-z atoms |
| CN117018234A (zh) * | 2013-08-16 | 2023-11-10 | 加利福尼亚大学董事会 | 硅酮基肠道ct对比材料 |
-
2014
- 2014-03-17 US US14/215,827 patent/US11033640B2/en active Active
- 2014-03-17 ES ES14764088T patent/ES2897624T3/es active Active
- 2014-03-17 WO PCT/US2014/030295 patent/WO2014145509A1/en not_active Ceased
- 2014-03-17 CN CN201480022822.8A patent/CN105142680A/zh active Pending
- 2014-03-17 EP EP21190284.6A patent/EP3984560A1/en active Pending
- 2014-03-17 EP EP14764088.2A patent/EP2968619B1/en active Active
- 2014-03-17 CN CN201810611475.2A patent/CN108743976B/zh active Active
- 2014-03-17 JP JP2016503369A patent/JP2016516072A/ja active Pending
-
2018
- 2018-03-05 JP JP2018038401A patent/JP6843787B2/ja active Active
-
2020
- 2020-08-28 JP JP2020144080A patent/JP2020193223A/ja active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3592185A (en) * | 1967-04-18 | 1971-07-13 | Yeda Res & Dev | Ferromagnetic contrast media and method of use |
| JPS63255237A (ja) * | 1987-03-24 | 1988-10-21 | シリカ・ゲル・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング・アドゾルプチオンス‐テヒニーク・アパラーテバウ | 生理学的に認容される超常磁性液体組成物,その製造方法並びにそれよりなる画像形成nmr,x線及び超音波診断剤 |
| JP2003160512A (ja) * | 1991-04-05 | 2003-06-03 | Imarx Pharmaceut Corp | 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用 |
| JPH07509716A (ja) * | 1992-08-07 | 1995-10-26 | ユニヴァーシティ オブ フロリダ | アーティファクトの無い画像コントラスト増強剤 |
| US20070258907A1 (en) * | 2006-04-24 | 2007-11-08 | Davis Mark E | Polymer-coated paramagnetic particles |
| EP2127682A1 (en) * | 2008-05-28 | 2009-12-02 | Deutsches Krebsforschungszentrum | X-ray contrast agent based on bismuth oxide-nanoparticles |
| WO2012080260A1 (en) * | 2010-12-13 | 2012-06-21 | Novartis Ag | Dimeric iap inhibitors |
| WO2012101524A2 (en) * | 2011-01-28 | 2012-08-02 | Dalhousie University | Radiopaque embolic particles |
Non-Patent Citations (2)
| Title |
|---|
| GAMARRA L F: "Characterization of superparamagnetic iron oxide coated with silicone used as contrast agent for mag", JOURNAL OF NANOSCIENCE AND NANOTECHNO,,20100201,VOL: 10, NR: 2, PAGE(S): 1153 - 1158,, JPN6017034342, 2010, ISSN: 0003811297 * |
| KATHRYN E. DEKRAFFT: "Zr- and Hf-based nanoscale metal?organic frameworks as contrast agents for computed tomography", JOURNAL OF MATERIALS CHEMISTRY, (2012 JAN 01) VOL. 22, NO. 35, PP. 18139-18144., JPN6017034344, 2012, ISSN: 0003811298 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2897624T3 (es) | 2022-03-02 |
| US20140276021A1 (en) | 2014-09-18 |
| JP6843787B2 (ja) | 2021-03-17 |
| EP2968619A1 (en) | 2016-01-20 |
| CN105142680A (zh) | 2015-12-09 |
| CN108743976B (zh) | 2021-10-29 |
| EP2968619A4 (en) | 2016-11-02 |
| JP2020193223A (ja) | 2020-12-03 |
| JP2018090624A (ja) | 2018-06-14 |
| US11033640B2 (en) | 2021-06-15 |
| EP2968619B1 (en) | 2021-08-11 |
| WO2014145509A1 (en) | 2014-09-18 |
| CN108743976A (zh) | 2018-11-06 |
| EP3984560A1 (en) | 2022-04-20 |
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| Vet—QV08BA02 | Uses and Administration |
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